CN106177849A - A kind of Chinese medicine composition treating osteoarthritis, neck prolapse of lumbar intervertebral disc and preparation method thereof - Google Patents

A kind of Chinese medicine composition treating osteoarthritis, neck prolapse of lumbar intervertebral disc and preparation method thereof Download PDF

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CN106177849A
CN106177849A CN201610670483.5A CN201610670483A CN106177849A CN 106177849 A CN106177849 A CN 106177849A CN 201610670483 A CN201610670483 A CN 201610670483A CN 106177849 A CN106177849 A CN 106177849A
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radix
rhizoma
medicine composition
chinese medicine
herba
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王信东
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Abstract

The invention belongs to technical field of Chinese medicines, it is specifically related to one and treats osteoarthritis, Chinese medicine composition of neck prolapse of lumbar intervertebral disc and preparation method thereof, this Chinese medicine composition is to consist of following crude drug: Radix Saposhnikoviae, Rhizoma Chuanxiong, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Herba Asari, Olibanum, Cortex schizophragmatis integrifolii radicis, Herba Schizonepetae, Myrrha, Rhizoma Homalomenae, Pericarpium Citri Reticulatae Viride, Herba Ephedrae, the Radix Angelicae Dahuricae, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, sand, Cortex Cinnamomi, Semen Momordicae, Flos Carthami, Radix Angelicae Sinensis, fresh Mulberry Chinese scholartree, Ramulus Salicis Babylonicae, Plumbum preparatium, Oleum sesami, the Chinese medicine composition that the present invention provides can promoting tissue regeneration by removing blood stasis, cold expelling is supported sliding, channels sootheing and network vessel quickening, expelling wind and removing dampness, treating both the principal and secondary aspects of a disease, for damp of having a cold, strain, the neck prolapse of lumbar intervertebral disc that wound causes, osteoarthritis, old stasis of blood trouble etc. are evident in efficacy, non-relapse after healing, and drug safety is convenient, have no side effect.

Description

A kind of treat osteoarthritis, the Chinese medicine composition of neck prolapse of lumbar intervertebral disc and preparation thereof Method
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of treat osteoarthritis, the Chinese medicine of neck prolapse of lumbar intervertebral disc Compositions and preparation method thereof.
Background technology
Osteoarthritis, neck prolapse of lumbar intervertebral disc are owing to wound, strain, wind-cold damp pathogen invade caused so that local bone glues Film is impaired, accumulates over a long period and causes arthralgia, swelling, deformation, for a long time, clinic over the course for the treatment of, oral medicine, Western medicine etc. Administering mode can not directly play a role at diseased region, and toxic and side effects is big, human body causes a certain degree of damage and reaches Curative effect less than hope.Unguentum therapy is one of outer treating method that tcm clinical practice is conventional, existing treatment neck prolapse of lumbar intervertebral disc More etc. the unguentum of disease, but cure rate is low, and relapse rate is high, and effect is the most notable.
Summary of the invention
The problem existed for prior art, the invention provides and a kind of treat osteoarthritis, neck prolapse of lumbar intervertebral disc Chinese medicine composition, this Chinese medicine composition is easy to use, cure rate is high, has no side effect.
Present invention also offers the preparation method of a kind of Chinese medicine composition treating osteoarthritis, neck prolapse of lumbar intervertebral disc, The method is the most efficient.
The technical scheme that the present invention is used to achieve these goals is:
The invention provides and a kind of treat osteoarthritis, the Chinese medicine composition of neck prolapse of lumbar intervertebral disc, be former by following weight Material medicine composition: Radix Saposhnikoviae 12g, Rhizoma Chuanxiong 12g, Radix Aconiti 12g, Radix Aconiti Kusnezoffii 12g, Scorpio 12g, Herba Asari 12g, Olibanum 12g, Cortex schizophragmatis integrifolii radicis 12g, Herba Schizonepetae 12g, Myrrha 12g, Rhizoma Homalomenae 12g, Pericarpium Citri Reticulatae Viride 12g, Herba Ephedrae 12g, Radix Angelicae Dahuricae 10g, Rhizoma Zingiberis 10g, Rhizoma Et Radix Notopterygii 10g, sand 10g, Cortex Cinnamomi 10g, Semen Momordicae 10g, Flos Carthami 20g, Radix Angelicae Sinensis 20g, fresh Mulberry Chinese scholartree 1 chi, Ramulus Salicis Babylonicae 1 chi, Plumbum preparatium 650g, Oleum sesami 1250g.
Further, the dosage form of Chinese medicine composition provided by the present invention is unguentum.
Present invention also offers the preparation method of a kind of Chinese medicine composition treating osteoarthritis, neck prolapse of lumbar intervertebral disc, Comprise the following steps:
(1) by Radix Saposhnikoviae, Rhizoma Chuanxiong, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Herba Asari, Cortex schizophragmatis integrifolii radicis, Herba Schizonepetae, Rhizoma Homalomenae, Pericarpium Citri Reticulatae Viride, Herba Ephedrae, the Radix Angelicae Dahuricae, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, sand, Cortex Cinnamomi, Semen Momordicae, Flos Carthami, Radix Angelicae Sinensis, fresh Mulberry Chinese scholartree, Ramulus Salicis Babylonicae are simultaneously introduced heating in pot, add after 10 minutes Olibanum, Myrrha, stirs, standby；
(2) Oleum sesami is placed in pot, adds crude drug heated in step (1), within fried 30 minutes, to shrivelled, filter, obtain medicine Oil；
(3) being refined 15-25 minute by medicine oil, add Plumbum preparatium, continuation refining medicine oil droplet, to entering indiffusion in water, obtains red oil mixing Thing；
(4) pellet oil mixture is poured in cold water 20 minutes, obtain ointment, ointment is placed in cloth central authorities, when drying in the air to surface solidification Alignment folds.
Above medical material formula is according to clinical testing data, obtains through scientific method screening, to different situations patient, Such as patients whose symptoms were less severe, symptom very severe patient or the patient of different age group, for reaching same effect, ensureing that each raw material is joined Under conditions of constant, dose can be increased and decreased accordingly, but dose amplitude of fluctuation is unsuitable excessive, is not to be exceeded dose 15%.
The invention have the benefit that Chinese medicine composition that the present invention provides promoting tissue regeneration by removing blood stasis, cold expelling can be supported sliding, relaxing muscles and tendons and lead to Network, expelling wind and removing dampness, treating both the principal and secondary aspects of a disease, the neck prolapse of lumbar intervertebral disc that damp of having a cold, strain, wound are caused, osteoarthritis, old Old property stasis of blood trouble etc. are evident in efficacy, non-relapse after healing, and drug safety facilitates, has no side effect.
Detailed description of the invention
In order to be more fully understood that the essence of the present invention, below by specific embodiment and clinical testing data to the present invention's Technical scheme is further elaborated.
Embodiment 1
A kind for the treatment of osteoarthritis, the Chinese medicine composition of neck prolapse of lumbar intervertebral disc, formula is: Radix Saposhnikoviae 12g, Rhizoma Chuanxiong 12g, Radix Aconiti 12g, Radix Aconiti Kusnezoffii 12g, Scorpio 12g, Herba Asari 12g, Olibanum 12g, Cortex schizophragmatis integrifolii radicis 12g, Herba Schizonepetae 12g, Myrrha 12g, Rhizoma Homalomenae 12g, Pericarpium Citri Reticulatae Viride 12g, Herba Ephedrae 12g, Radix Angelicae Dahuricae 10g, Rhizoma Zingiberis 10g, Rhizoma Et Radix Notopterygii 10g, sand 10g, Cortex Cinnamomi 10g, Semen Momordicae 10g, Flos Carthami 20g, Radix Angelicae Sinensis 20g, fresh Mulberry Chinese scholartree 1 chi, Ramulus Salicis Babylonicae 1 chi, Plumbum preparatium 650g, Oleum sesami 1250g；
Concrete preparation method is as follows:
(1) by Radix Saposhnikoviae, Rhizoma Chuanxiong, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Herba Asari, Cortex schizophragmatis integrifolii radicis, Herba Schizonepetae, Rhizoma Homalomenae, Pericarpium Citri Reticulatae Viride, Herba Ephedrae, the Radix Angelicae Dahuricae, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, sand, Cortex Cinnamomi, Semen Momordicae, Flos Carthami, Radix Angelicae Sinensis, fresh Mulberry Chinese scholartree, Ramulus Salicis Babylonicae are simultaneously introduced slight fever in pot, are subsequently adding after 10 minutes Olibanum, Myrrha；
(2) Oleum sesami is placed in pot, adds crude drug heated in step (1), within fried 30 minutes, to shrivelled, filter, obtain medicine Oil；
(3) medicine oil is refined 20 minutes, add Plumbum preparatium, continue refining medicine oil droplet and enter indiffusion in water, obtain red oil mixture；
(4) pellet oil mixture is poured in cold water 20 minutes, obtain ointment, ointment is placed in cloth central authorities, when drying in the air to surface solidification Alignment folds, and the dose often forced on is 20g.
Embodiment 2
A kind for the treatment of osteoarthritis, the Chinese medicine composition of neck prolapse of lumbar intervertebral disc, formula is with embodiment 1；
Concrete preparation method is as follows:
(1) Oleum sesami is placed in pot, adds other crude drug in addition to Plumbum preparatium, within fried 30 minutes, to shrivelled, filter, obtain medicine oil；
(2) medicine oil is refined 20 minutes, add Plumbum preparatium, continue refining medicine oil droplet and enter indiffusion in water, obtain red oil mixture；
(3) pellet oil mixture is poured in cold water 20 minutes, obtain ointment, ointment is placed in cloth central authorities, when drying in the air to surface solidification Alignment folds, and the dose often forced on is 20g.
Clinical testing data:
Case: total patient 117 example, wherein, osteoarthritis patient 48 example, male 20 example, women 28 example；Prolapse of cervical intervertebral disc is suffered from Person 20 example, male 13 example, women 7 example；Lumbar intervertebral disc patient 49 example, male 40 example, women 9 example；Patient medical history is 2-18,
Using method: unguentum prepared by the embodiment of the present invention 1 is applied to site of disease, 30 days-60 days 1 patches, 90 days are a treatment Journey, external application 2 course for the treatment of.
Criterion of therapeutical effect:
Recovery from illness: symptom all disappears, functional activity recovers normal, and main doctor trained in Western medicine physico-chemical examination is normal；
Effective: symptomatology disappears or cardinal symptom disappears, and functional activity recovers substantially, normal work or physical labor can be participated in； Physico-chemical examination is normal；
Effective: cardinal symptom disappears substantially, major function activity substantially recovers or has made marked progress, and life can take care of oneself, work Having recovered with work capacity, main physico-chemical examination has improvement；
Invalid: to compare with before treatment, each side is all without progressive.
Concrete therapeutic outcome is shown in Table 1.
Table 1
During use, application site, without the generation of the untoward reaction such as edema, blister, erythra, has no anaphylaxis to patient.
Inventor, by when the plaster of preparation carries out clinical trial in embodiment 2, finds that cure rate is about 38%, and always has The scheme that efficiency provides compared with embodiment 1 reduces 12%.
Model case:
1, Wang, man, 56 years old, Fu Laishan town, Juxian County, Shandong Province rang wave head Wang Cun, tractor driver, and the right hand can not be praised, neck shoulder pain Bitterly, hospital is cervical spondylosis through physics and chemistry checkout and diagnosis, and through many places, treatment is had no result, the unguentum that in August, 15 begins to use the present invention to provide, Applying ointment or plaster and fully recover after 20d, follow up a case by regular visits to 1 year not recur, period does not has any discomfort symptom to occur.
2, thin certain, man, 62 years old, Bao Jia shop village, Yinan County, carpenter, for many years, hospital diagnosis is prolapse of lumbar intervertebral disc to lumbago, The unguentum that the present invention that applies ointment or plaster provides, fully recovers after 3 months, follows up a case by regular visits to 1 year not recur, and period does not has any discomfort symptom to occur.
3, Korea Spro, man, 55 years old, Han Jia vegetable garden village, Chengyang town, Juxian County, Shandong Province, double knee joint swelling are ached, it is impossible to bending, and ill 6 Year, the unguentum that the present invention that starts in by the end of October, 15 to apply ointment or plaster provides, two patch rehabilitations after 4 months, within 1 year, to follow up a case by regular visits to not recur, period does not has Any discomfort symptom occurs.
4, money, man, 65 years old, Qian Jiatun village, Chengyang town, Juxian County, pain in the lumbar region 16 years, through hospital, Physico-chemical tests was diagnosed as between lumbar vertebra Dish highlights, Multiple Hospitalization, recurrence, the unguentum that in August, 15 begins to use the present invention to provide, and after the first note 1 month, symptom alleviates, even Rehabilitation after continuous half a year of applying ointment or plaster, follows up a case by regular visits to 1 year not recur.
5, Ma, man, 45 years old, Juxian County, Shandong Province Liu Guanzhuanzhen, hospital was scapulohumeral periarthritis through physics and chemistry checkout and diagnosis, and the right hand is praised Limited, pain is hard to bear, the present invention that applies ointment or plaster provide unguentum after, rehabilitation after 1 month, follow up a case by regular visits to 1 year not recur, period do not have any not Suitable symptom occurs.

Claims (3)

1. treat osteoarthritis, the Chinese medicine composition of neck prolapse of lumbar intervertebral disc for one kind, it is characterised in that be former by following weight Material medicine composition: Radix Saposhnikoviae 12g, Rhizoma Chuanxiong 12g, Radix Aconiti 12g, Radix Aconiti Kusnezoffii 12g, Scorpio 12g, Herba Asari 12g, Olibanum 12g, Cortex schizophragmatis integrifolii radicis 12g, Herba Schizonepetae 12g, Myrrha 12g, Rhizoma Homalomenae 12g, Pericarpium Citri Reticulatae Viride 12g, Herba Ephedrae 12g, Radix Angelicae Dahuricae 10g, Rhizoma Zingiberis 10g, Rhizoma Et Radix Notopterygii 10g, sand 10g, Cortex Cinnamomi 10g, Semen Momordicae 10g, Flos Carthami 20g, Radix Angelicae Sinensis 20g, fresh Mulberry Chinese scholartree 1 chi, Ramulus Salicis Babylonicae 1 chi, Plumbum preparatium 650g, Oleum sesami 1250g.
Chinese medicine composition the most according to claim 1, it is characterised in that the dosage form of described Chinese medicine composition is unguentum.
3. the preparation method of a Chinese medicine composition as claimed in claim 1, it is characterised in that comprise the following steps:
(1) by Radix Saposhnikoviae, Rhizoma Chuanxiong, Radix Aconiti, Radix Aconiti Kusnezoffii, Scorpio, Herba Asari, Cortex schizophragmatis integrifolii radicis, Herba Schizonepetae, Rhizoma Homalomenae, Pericarpium Citri Reticulatae Viride, Herba Ephedrae, the Radix Angelicae Dahuricae, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, sand, Cortex Cinnamomi, Semen Momordicae, Flos Carthami, Radix Angelicae Sinensis, fresh Mulberry Chinese scholartree, Ramulus Salicis Babylonicae are simultaneously introduced heating in pot, add after 10 minutes Olibanum, Myrrha, stirs, standby；
(2) Oleum sesami is placed in pot, adds crude drug heated in step (1), within fried 30 minutes, to shrivelled, filter, obtain medicine Oil；
(3) being refined 15-25 minute by medicine oil, add Plumbum preparatium, continuation refining medicine oil droplet, to entering indiffusion in water, obtains red oil mixing Thing；
(4) pellet oil mixture is poured in cold water 20 minutes, obtain ointment, ointment is placed in cloth central authorities, when drying in the air to surface solidification Alignment folds.
CN201610670483.5A 2016-08-16 2016-08-16 A kind of Chinese medicine composition treating osteoarthritis, neck prolapse of lumbar intervertebral disc and preparation method thereof Pending CN106177849A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1391943A (en) * 2002-06-10 2003-01-22 郭好建 Chinese medicine paste for curing osteoarthropathy and preparing method
CN101181615A (en) * 2007-11-28 2008-05-21 吴公河 Plaster for curing neck shoulder waist leg pain affection as well as preparation method
CN101244252A (en) * 2008-03-13 2008-08-20 张金星 Chinese medicine label for eliminating ache and preparation thereof
CN102266541A (en) * 2011-07-11 2011-12-07 谢书芳 Chinese medicinal plaster for treating hyperosteogeny or hyperosteogeny pain

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1391943A (en) * 2002-06-10 2003-01-22 郭好建 Chinese medicine paste for curing osteoarthropathy and preparing method
CN101181615A (en) * 2007-11-28 2008-05-21 吴公河 Plaster for curing neck shoulder waist leg pain affection as well as preparation method
CN101244252A (en) * 2008-03-13 2008-08-20 张金星 Chinese medicine label for eliminating ache and preparation thereof
CN102266541A (en) * 2011-07-11 2011-12-07 谢书芳 Chinese medicinal plaster for treating hyperosteogeny or hyperosteogeny pain

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田三强: ""自制消痛散外敷为主综合治疗颈椎病疗效观察"", 《中医正骨》 *

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Application publication date: 20161207