CN106177513A - 一种治疗心脏病引起下肢水肿的中药组合物 - Google Patents
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Abstract
本发明提供一种治疗心脏病引起下肢水肿的中药组合物，按重量百分比，包括以下组份：丹参5‑10份，小血藤6‑12份，益母草11‑16份，生黄芪8‑13份，川芎7‑14份，葛根素5‑10份，天麻3‑5份，三七3‑6份。本发明中药组合物通过科学配伍，相辅相成，共凑具有治疗心脏病、通畅气血、消除水肿的功效，且无毒副作用。并且其组分药源广、配制简便、无毒副作用。
Description
技术领域
本发明涉及中医药领域，尤其涉及一种治疗心脏病引起下肢水肿的中药组合物。
背景技术
由于老年人身体脏器功能衰退，血液循环不畅，当心脏功能减退，下肢静脉栓塞、静脉血回流出现问题时，就可能表现为脚变大。另外，老人营养不良，易产生低蛋白血症。身体水分难于排出体外，堆积在下肢，造成下肢肿大的现象。
发明内容
为了解决以上技术问题，本发明人在整体观及辨证论治理论指导下，吸取传统医学理论精华，结合多年的临床经验及现代理论，提供了一种疗效显著，针对心脏病引起下肢水肿标本兼治的中药组合物。按重量百分比，包括以下组份：丹参5-10份，小血藤6-12份，益母草11-16份，生黄芪8-13份，川芎7-14份， 葛根素5-10份，天麻3-5份，三七3-6份。
本发明采用以上技术方案，其优点在于，小血藤行气活血、散瘀止痛 ，丹参活血祛瘀、通经止痛，小血藤：辛，温。功能主治：行气，止痛，活血，散瘀。治跌打损伤，风湿麻木；筋骨；黄芪，有益气固表、利水消肿、脱毒、生肌的功效，适用于自汗、盗汗、血痹、浮肿、痈疽不溃或溃久不敛、等症。现代医学证明，黄芪具有降低血液黏稠度、减少血栓形成、降低血压、保护心脏、双向调节血糖、抗自由基损伤、抗衰老、抗缺氧、抗肿瘤、增强机体免疫力作用，可用来治疗心脏病、高血压、糖尿病等症。黄芪还能扩张血管，改善皮肤血液循环和营养状况，故对慢性溃疡久不愈合者有效。其还能消除肾炎患者的蛋白尿，保护肝脏，防止肝糖原减少。天麻能增加脑血流量，降低脑血管阻力，轻度收缩脑血管，增加冠状血管流量。三七具有散瘀止血，消肿定痛之功效。主治咯血，吐血，衄血，便血，崩漏，外伤出血，胸腹刺痛，跌仆肿痛。《本草纲目》云：“三七止血，散血，定痛。”《玉揪药解》云：“三七和营止血，通脉行瘀，行瘀血而敛新血。”川芎活血行气祛风止痛，益母草活血调经，利尿消肿。用于月经不调，痛经，经闭，恶露不尽，水肿尿少;急性肾炎水肿。葛根素能扩张脑血管，增加脑血流量，改善椎基底动脉供血不足等。葛根素能够改善心肌缺血，葛根素对去甲肾上腺素作用下对主动脉有促进和抑制收缩的双向作用。
优选的，其制成汤剂、散剂、丸剂、颗粒剂、口服液、片剂、胶囊剂、糖浆中的一种或多种。
其中，所述中成药经过常规中药加工工艺，制成的丸、散或汤剂。
用量及用法：服用本发明的中药汤剂，每日一剂，15 天为一疗程，一般2-3 个疗程即可治愈。
本发明的有益效果：本发明中药组合物通过科学配伍，相辅相成，共凑具有治疗心脏病、通畅气血、消除水肿的功效，且无毒副作用。并且其组分药源广、配制简便、无毒副作用。
具体实施方式
下面对本发明的较优的实施例作进一步的详细说明：
实施例1
李某某，女，45 岁，下肢出现水肿症状半年，肿处按之凹陷，抬高肢体后，水肿可减退，患者变现有肺水肿、咯血和右心衰竭的症状；经过医生的检查诊断后发现，患者患有心脏病；
药用：丹参5克，小血藤6克，益母草11克，生黄芪8克，川芎7克，葛根5克，天麻3克，三七3克。
服用本发明的中药汤剂，每日一剂，服用两个疗程后，水肿明显消肿，继续服用一个疗程，水肿消失，治愈，2年后随访无复发。
实施例2
张某某，男，43 岁，患者下肢水肿数月，伴有眩晕耳鸣、形体消瘦、失眠多梦等症状，舌淡苔薄，脉沉弦，在医院检查后发现，患者患有风湿性心脏病；
药用：丹参8克，小血藤9克，益母草13克，生黄芪9克，川芎14克，葛根5克，天麻5克，三七4克。
服用本发明的中药汤剂，每日一剂，连服 十余剂，水肿明显好转，其他症状消失，继续服用两个疗程，水肿痊愈，2年后随访无复发。
实施例3
周某某，女，60 岁，下肢水肿一年，严重时影响行走，局部红肿、疼痛，淋巴结肿大，有压痛，常伴有突发性高热，患者患风湿性心脏病、联合瓣膜病，心功能四级，有腹水，睡眠不好，使用过多种药物治疗，未见起色；
药用：丹参7克，小血藤8克，益母草13克，生黄芪11克，川芎12克，葛根9克，天麻4克，三七5克。
每日一剂，连服两个疗程，水肿明显减轻，继续服用一个疗程，水肿痊愈，2年后随访无复发。
实施例4
张某，男，59岁。患者变现有肺水肿、咯血和右心衰竭的症状，患者劳动或上楼梯时经常出现呼吸困难的症状，日常失眠、疲乏、食欲减退；去医院就诊，诊断为风湿性心脏病，在进行了一段时间的治疗后，患者的病情好转，但时常会出现反复。
药用：丹参8克，小血藤10克，益母草13克，生黄芪10克，川芎11克，葛根8克，天麻4克，三七5克。
患者开始服用中药制剂，在服用了4个疗程后，患者的症状得到了有效的控制，坚持服用9个疗程后，患者的症状消失，，2年后随访无复发。
实施例5
李某，女，57岁。患者在躯干或四肢的内侧皮肤可见淡红色环形红斑，中央苍白；在大关节伸侧，尤其是肘、膝及腕关节，枕骨区或胸、腰椎棘突等部位可见2～5mm的皮下小结，无压痛，不与皮肤粘连，可移动。在医院检查后发现，患者患有风湿性心脏病。
药用：丹参6克，小血藤8克，益母草13克，生黄芪10克，川芎9克，葛根8克，天麻5克，三七5克。
在服用了3个疗程后患者的症状感到缓解减轻，坚持服用8个疗程后患者的症状基本消失，2年后随访无复发。
实施例6
临床资料
申请人选取了70例病例进行临床试验，随机分为治疗组和对照组，每组35例。其中治疗组男性15例，女性20例；平均年龄55±4，平均病程3 .5±1 .0年。对照组男性17例，女性18例；平均年龄55±4年，平均病程3 .2±1 .2。两组患者的年龄、性别、体重、患病时间、发病症状等基线资料经统计学分析，差异无统计学意义( P＞0 .05 )，具有可比性。
诊断标准：
患者均具备以下症状表现：心慌气短、乏力、咳嗽、下肢水肿等。
治疗方法：
治疗组患者服用本发明中的中药制剂进行治疗，每日1剂，15剂为1疗程。对照组中患者治疗使用洋地黄制剂，利尿剂和血管扩张剂。
疗效标准：
治愈：患者的心慌气短、乏力、咳嗽、下肢水肿、咳粉红色泡沫痰等症状消失。
显效：患者的心慌气短、乏力、咳嗽、下肢水肿、咳粉红色泡沫痰等症状得到缓解。
有效：患者的心慌气短、乏力、咳嗽、下肢水肿、咳粉红色泡沫痰等症状减轻。
无效：患者的心慌气短、乏力、咳嗽、下肢水肿、咳粉红色泡沫痰等临床表现与治疗
前无明显变化或者加重。
疗效结果：
治疗组中治愈15例，显效13例，有效7例，无效0例，总有效率为100％；对照组中治愈10例，显效8例，有效7例，无效5例，总有效率为81 .6％。
由此，我们可以发现，本发明中的中药制剂疗效明显优于以往的治疗方法，能够安全快速的心脏病引起下肢水肿的中药组合物及其引起的各种症状。
以上内容是结合具体的优选实施方式对本发明所作的进一步详细说明，不能认定本发明的具体实施只局限于这些说明。对于本发明所属技术领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干简单推演或替换，都应当视为属于本发明的保护范围。
Claims (3)
1.一种治疗心脏病引起下肢水肿的中药组合物，其特征在于，按重量百分比，包括以下组份：丹参5-10份，小血藤6-12份，益母草11-16份，生黄芪8-13份，川芎7-14份， 葛根素5-10份，天麻3-5份，三七3-6份。
2.如权利要求1所述的治疗心脏病引起下肢水肿的中药组合物，其特征在于，其制成汤剂、散剂、丸剂、颗粒剂、口服液、片剂、胶囊剂、糖浆中的一种或多种。
3.一种治疗心脏病引起下肢水肿的中药组合物，其特征在于，所述中成药为由权利要求1所述的中药组合物，经过常规中药加工工艺，制成的丸、散或汤剂。
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