CN106177250A - A kind of Chinese medicine composition treating chronic nephritis - Google Patents
A kind of Chinese medicine composition treating chronic nephritis Download PDFInfo
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- CN106177250A CN106177250A CN201610746287.1A CN201610746287A CN106177250A CN 106177250 A CN106177250 A CN 106177250A CN 201610746287 A CN201610746287 A CN 201610746287A CN 106177250 A CN106177250 A CN 106177250A
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- 239000003814 drug Substances 0.000 title claims abstract description 41
- 239000000203 mixture Substances 0.000 title claims abstract description 38
- 206010018367 Glomerulonephritis chronic Diseases 0.000 title claims abstract description 33
- 241000222640 Polyporus Species 0.000 claims abstract description 17
- 238000003860 storage Methods 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 238000002360 preparation method Methods 0.000 claims description 13
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The invention discloses a kind of Chinese medicine composition treating chronic nephritis, it is characterised in that this Chinese medicine composition includes following raw medicinal material: Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus.This traditional Chinese medicinal composition raw materials material source is wide, cheap and easy to get, and formula is reasonable, and treatment chronic nephritis is evident in efficacy.
Description
Technical field
The invention belongs to Chinese medicine formulation art, be specifically related to a kind of Chinese medicine composition treating chronic nephritis.
Background technology
Chronic nephritis is the abbreviation of chronic glomerulonephritis, is a kind of common and the chronic kidney disease of refractory.Clinical with
Edema, albuminuria, hematuria, hypertension are characterized, and primary disease is multiple is born in person between twenty and fifty, are to send out after hemolytic streptococcus is infected by body
Raw allergic disease, pathological changes may often be such that bilateral renal diffusivity pathological changes.Mainly being presented with of chronic nephropathy: (1) edema；
(2) hypertension；(3) pain over renal region and renal colic；(4) urinary irritation symptoms (i.e. urgent micturition, dysurea, frequent micturition)；(5) paruria (bag
Include hypourocrinia, albuminuria, hematuria, cylinderuria, leukocyturia, pyuria and bacteriuria, the kidney function test positive etc..Chronic nephropathy is such as
Fail timely and effective treatment, the progress that causes that sb.'s illness took a turn for the worse, then to delay with the course of disease, Patients with Chronic Renal Disease will develop into chronic renal merit
Can not entirely, renal failure, ultimately form uremia.
The at present doctor trained in Western medicine therapy such as conventional dialysis and renal transplantation clinically, dialysis can only sustain life, and produce dependency and
Dialysis syndrome, renal transplantation success rate is low, and rejection is also difficult to solve for the moment, and hormonotherapy side effect is obvious, and easily multiple
Sending out, the somewhat expensive of dialysis and renal transplantation often makes numerous patients be difficult to bear in addition.
Chronic nephritis had the longest a period of time before developing into renal failure, this stage active treatment, used Chinese medicine to carry out
Conditioning, the most economical, moreover it is possible to obtain the more preferable curative effect of relative doctor trained in Western medicine, it may be said that Chinese medicine is very to treatment chronic nephritis
Have superiority.
Chinese traditional treatment chronic nephritis uses righting with the eliminating evil and eliminating evil principle being treatment with peace just two big rules.Chronic nephritis
Generation, recurrence, protracted course of disease, relevant with some antibacterial or virus infection.Therefore, efficiently controlling infection is to promote the state of an illness to fully recover
With the key of prevention of recurrence, the Chinese herbal medicine of antipyretic and antidotal type has stronger anti-infectious function.So, tcm clinical practice treatment is chronic
During nephritis, on the basis of tonifying speen and tonifying kidney, often add some heat-clearing and toxic substances removing or activating blood circulation to dissipate blood stasis medicine, to improve clinical efficacy.
Summary of the invention
It is desirable to provide a kind of Chinese medicine composition treating chronic nephritis.
For achieving the above object, a kind of Chinese medicine composition treating chronic nephritis of the present invention, specific embodiments is:
A kind of Chinese medicine composition treating chronic nephritis of the present invention, it is characterised in that this Chinese medicine composition includes the most former
Material medical material: Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus.
A kind of Chinese medicine composition treating chronic nephritis of the present invention, these Chinese medicine composition prescription parts by weight are calculated as:
Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong each 10-20 part, stores 5-15 part, Herba Pyrolae, Herba Poae Sphondylodis each 15-30 part, Polyporus 20-40 part.
A kind of Chinese medicine composition treating chronic nephritis of the present invention, these Chinese medicine composition prescription parts by weight are calculated as:
Each 15 parts of Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, stores 10 parts, each 20 parts of Herba Pyrolae, Herba Poae Sphondylodis, Polyporus 25 parts.
A kind of Chinese medicine composition treating chronic nephritis of the present invention, this Chinese medicinal composition preparation preparation method include with
Lower step:
1) weigh ingredients respectively by Chinese prescription, wash away impurity, pulverize the most respectively, cross 60-80 mesh sieve, standby；
2) take Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus coarse powder, add medical material total amount 5-10 times
The water soaking of amount 1-3 hour, then decocts 1-4 time, each 1-2 hour, filters and retain filtering residue, merging filtrate, filter vacuum
Being evaporated under the conditions of 60 DEG C survey relative density is the concentrated solution of 1.05-1.15, obtains water extracting liquid；
3) toward step 2) in filtering residue in add medical material total amount 5-10 times amount volume fraction be the ethanol of 60-80%, reflux, extract, 2-
3 times, filtering, merging filtrate, it is the concentrated solution of 1.05-1.15 that filter vacuum is evaporated under the conditions of 60 DEG C survey relative density,
Obtain alcohol extraction concentrated solution；
4) combining step 2) and 3) concentrated solution, it is dried, extractum is pulverized, preparation.
A kind of Chinese medicine composition treating chronic nephritis of the present invention, this Chinese medicinal composition preparation can be granule,
Tablet, capsule, patch, pill.
A kind of Chinese medicine composition treating chronic nephritis of the present invention, this Chinese medicinal composition preparation is in treatment chronic nephritis
In application.
A kind of Chinese medicine composition treating chronic nephritis of the present invention, this Chinese medicinal composition preparation primary raw material medicine is being controlled
Treat the application in chronic nephritis.
The each component analysis of the present invention:
Radix Salviae Miltiorrhizae: bitter, is slightly cold.GUIXIN, pericardium, Liver Channel.Health-care effect: blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle, mind tranquilizing and the heart calming.
Herba Leonuri: pungent, bitter, is slightly cold.GUIXIN, liver, bladder warp.Blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema.
Radix Angelicae Sinensis: sweet, pungent, temperature.Return liver, the heart, spleen channel.Promoting blood circulation and stopping pain, tonifying blood and regulating menstruation, loosening bowel to relieve constipation.
Rhizoma Chuanxiong: pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.
Store: bitter, be slightly cold.Return bladder warp.Relieving stranguria by diuresis, killing parasites for relieving itching.
Herba Pyrolae: micro-sweet, temperature.Enter liver, kidney, lung meridian.Nourishing liver, invigorating kidney, bone and muscle strengthening, dispel the wind, dehumidifying, hemostasis.
Herba Poae Sphondylodis: sweet light, flat.Enter spleen, bladder two warp, heat-clearing and toxic substances removing, diuresis, pain relieving.
Polyporus: sweet, flat.Enter kidney, bladder warp.Promoting diuresis to eliminate damp pathogen.
Prescription analysis of the present invention:
The present invention selects Radix Salviae Miltiorrhizae, Herba Pyrolae nourishing the liver and kidney, selects Herba Poae Sphondylodis, stores removing toxic substances, selects Radix Angelicae Sinensis, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling,
Herba Leonuri, Polyporus promoting diuresis to eliminate damp pathogen, antiinflammatory, Chinese medicine preparation of the present invention has effect of nourishing the liver and kidney, blood circulation promoting and blood stasis dispelling, is that treatment is chronic
The for oral administration pure Chinese herbal medicine composition preparation of nephritis.By Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus
Deng monarch in crude drug, minister, help, be allowed between synergism, bring out the best in each other, so that patient's toxin is effectively got rid of, thus reach
To letting out turbid heat-clearing and toxic substances removing, purging FU-organs rushes down turbid, diuretic, effect of enriching yin and nourishing kidney.
Detailed description of the invention
Example below, only for further illustrating the present invention, limits the scope of the invention the most in any form.
Embodiment 1
Prescription: each 15 parts of Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, stores 10 parts, each 20 parts of Herba Pyrolae, Herba Poae Sphondylodis, Polyporus 25 parts.
Embodiment 2
Prescription: each 20 parts of Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, stores 18 parts, each 15 parts of Herba Pyrolae, Herba Poae Sphondylodis, Polyporus 20 parts.
Embodiment 3
Prescription: each 15 parts of Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, stores 20 parts, each 18 parts of Herba Pyrolae, Herba Poae Sphondylodis, Polyporus 15 parts.
Embodiment 4
Prescription: each 15 parts of Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, stores 15 parts, each 20 parts of Herba Pyrolae, Herba Poae Sphondylodis, Polyporus 30 parts.
Embodiment 1-4 formulation preparation method:
1) weigh ingredients respectively by Chinese prescription, wash away impurity, pulverize the most respectively, cross 60-80 mesh sieve, standby；
2) take Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus coarse powder, add medical material total amount 8 times amount
Water soaking 2 hours, then decocts 2 times, each 1-2 hour, filters and retain filtering residue, merging filtrate, filter vacuum concentrating under reduced pressure
Surveying relative density under the conditions of 60 DEG C is the concentrated solution of 1.05-1.15, obtains water extracting liquid；
3) toward step 2) in filtering residue in add medical material total amount 6 times amount volume fraction be the ethanol of 60-80%, reflux, extract, 2 times,
Filtering, merging filtrate, it is the concentrated solution of 1.05-1.15 that filter vacuum is evaporated under the conditions of 60 DEG C survey relative density, obtains alcohol
Carry concentrated solution；
4) combining step 2) and 3) concentrated solution, it is dried, extractum is pulverized, preparation (granule, tablet, capsule, patch, ball
Agent).
Clinical data:
Randomly drawing clinical chronic nephritis case 100 example, the age, from 25-65,40 years old mean age, takes the present invention and implements
Example 1 granule, once a bag, three times on the one, 15 days be a course for the treatment of.
Curative effect diagnostic criteria:
Cure: the symptoms such as edema, oliguria, hematuria, hypertension disappear entirely；Effective: the symptoms such as edema, oliguria, hematuria, hypertension show
Work alleviates；Effective: the symptoms such as edema, oliguria, hematuria, hypertension are improved, and serum urea nitrogen, creatinine clearance rate are stable, routine urinalysis
At normal range value；Invalid: symptom, sign have no and be obviously improved, and even deteriorate or turn operative treatment.
After above-mentioned patient takes 5-8 the course for the treatment of of granule of the present invention, curing 5, effective 28, effective 41, invalid 26, the present invention is to controlling
Treat chronic nephritis total effective rate 74%.
Claims (7)
1. the Chinese medicine composition treating chronic nephritis, it is characterised in that this Chinese medicine composition includes following raw medicinal material: red
Ginseng, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus.
A kind of Chinese medicine composition treating chronic nephritis, it is characterised in that at this Chinese medicine composition
Side's parts by weight are calculated as: Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong each 10-20 part, store 5-15 part, Herba Pyrolae, each 15-30 of Herba Poae Sphondylodis
Part, Polyporus 20-40 part.
A kind of Chinese medicine composition treating chronic nephritis, it is characterised in that at this Chinese medicine composition
Side's parts by weight are calculated as: each 15 parts of Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, store 10 parts, each 20 parts of Herba Pyrolae, Herba Poae Sphondylodis, Polyporus
25 parts.
A kind of Chinese medicine composition treating chronic nephritis, it is characterised in that this Chinese medicine composition system
Agent preparation method comprises the following steps:
1) weigh ingredients respectively by Chinese prescription, wash away impurity, pulverize the most respectively, cross 60-80 mesh sieve, standby；
2) take Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, storage, Herba Pyrolae, Herba Poae Sphondylodis, Polyporus coarse powder, add medical material total amount 5-10 times
The water soaking of amount 1-3 hour, then decocts 1-4 time, each 1-2 hour, filters and retain filtering residue, merging filtrate, filter vacuum
Being evaporated under the conditions of 60 DEG C survey relative density is the concentrated solution of 1.05-1.15, obtains water extracting liquid；
3) toward step 2) in filtering residue in add medical material total amount 5-10 times amount volume fraction be the ethanol of 60-80%, reflux, extract, 2-
3 times, filtering, merging filtrate, it is the concentrated solution of 1.05-1.15 that filter vacuum is evaporated under the conditions of 60 DEG C survey relative density,
Obtain alcohol extraction concentrated solution；
4) combining step 2) and 3) concentrated solution, it is dried, extractum is pulverized, preparation.
5. according to the Chinese medicine composition treating chronic nephritis a kind of described in any one of claim 1-5, it is characterised in that this Chinese medicine
Composite preparation can be granule, tablet, capsule, patch, pill.
A kind of Chinese medicine composition treating chronic nephritis, it is characterised in that this Chinese medicine composition system
Agent application in treatment chronic nephritis.
A kind of Chinese medicine composition treating chronic nephritis, it is characterised in that this Chinese medicine composition system
The application in treatment chronic nephritis of the agent primary raw material medicine.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111686008A (en) * | 2020-07-20 | 2020-09-22 | 温州海鹤药业有限公司 | Mixed-decocting traditional Chinese medicine phosphorus removal process |
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| CN101066293A (en) * | 2007-05-23 | 2007-11-07 | 陈江 | Red sage root and angelica water |
| CN103083398A (en) * | 2012-12-24 | 2013-05-08 | 林学荣 | Drug for treating chronic nephritis and preparation method of drug |
| CN104043080A (en) * | 2014-06-13 | 2014-09-17 | 陈镇刚 | Traditional Chinese medicine composition capable of treating nephritis and preparation method thereof |
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| CN101066293A (en) * | 2007-05-23 | 2007-11-07 | 陈江 | Red sage root and angelica water |
| CN103083398A (en) * | 2012-12-24 | 2013-05-08 | 林学荣 | Drug for treating chronic nephritis and preparation method of drug |
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