CN106177158A - 一种治疗过敏性鼻炎的丸剂药物及其制备方法 - Google Patents

一种治疗过敏性鼻炎的丸剂药物及其制备方法 Download PDF

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CN106177158A
CN106177158A CN201610830603.3A CN201610830603A CN106177158A CN 106177158 A CN106177158 A CN 106177158A CN 201610830603 A CN201610830603 A CN 201610830603A CN 106177158 A CN106177158 A CN 106177158A
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Abstract

本发明属于中医药技术领域，目的是根据中医对过敏性鼻炎的认识机理而提供的一种治疗过敏性鼻炎的丸剂药物，所述药物的各个组分及其质量份比如下：黄芪9～32g、茯苓10～16g、白术8～16g、防风5～12g、紫苏梗5～12g、银柴胡5～10g、乌梅4～8g、玄参15～25g、五味子3～16g、蝉蜕3～8g、辛夷5～15g、苍耳子8～16g、白芷3～12g、桔梗3～12g、细辛2～6g、白蒺藜6～12g、薄荷3～7g，蜂蜜适量；本发明提供的药物是一个标本兼治的中药组方。

Description

一种治疗过敏性鼻炎的丸剂药物及其制备方法
技术领域
本发明涉及中医药技术领域，具体涉及一种治疗过敏性鼻炎的丸剂药物，特别是供过敏性鼻炎患者使用的丸剂药物及其制备方法的领域。
背景技术
医者认为：过敏性鼻炎即变应性鼻炎，是指特应性个体接触变应原后，主要由IgE介导的介质（主要是组胺）释放，并有多种免疫活性细胞和细胞因子等参与的鼻黏膜非感染性炎性疾病。其发生的必要条件有三个：a、特异性抗原即引起机体免疫反应的物质；b、特应性个体即所谓个体差异、过敏体质；c、特异性抗原与特应型个体二者相遇。变应性鼻炎是一个全球性健康问题，可导致许多疾病和劳动力丧失。
那么，就如何找到一种可有效治疗过敏性鼻炎的药物，是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗过敏性鼻炎上，人们逐渐意识到了中医治疗上述过敏性鼻炎的优点，且在治疗过程中毒副作用小、费用低等优势，针对现有西医治疗上述过敏性鼻炎的现状，本发明的目的是在于提供一种治疗过敏性鼻炎的丸剂药物，以解决过敏性鼻炎患者早日恢复健康的问题。该药物是以常见的中药为原料，具有见效快、疗效显著等特点，并可有效治疗上述过敏性鼻炎。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗过敏性鼻炎的丸剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪9～32g、茯苓10～16g、白术8～16g、防风5～12g、紫苏梗5～12g、银柴胡5～10g、乌梅4～8g、玄参15～25g、五味子3～16g、蝉蜕3～8g、辛夷5～15g、苍耳子8～16g、白芷3～12g、桔梗3～12g、细辛2～6g、白蒺藜6～12g、薄荷3～7g，蜂蜜适量。
一种治疗过敏性鼻炎的丸剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪15～28g、茯苓11～14g、白术10～14g、防风8～11g、紫苏梗8～11g、银柴胡7～9g、乌梅5～7g、玄参18～22g、五味子8～14g、蝉蜕5～7g、辛夷8～13g、苍耳子10～14g、白芷8～11g、桔梗8～11g、细辛3～5.5g、白蒺藜8～11g、薄荷4～6g，蜂蜜适量。
一种治疗过敏性鼻炎的丸剂药物及其制备方法，其特征在于，所述“最佳方案”的药物的各个组分及其质量份比如下所示：
黄芪25g、茯苓13g、白术13g、防风10g、紫苏梗10g、银柴胡8g、乌梅6g、玄参20g、五味子13g、蝉蜕6g、辛夷12g、苍耳子13g、白芷10g、桔梗10g、细辛5g、白蒺藜10g、薄荷5g，蜂蜜适量。
一种治疗过敏性鼻炎的丸剂药物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、除蜂蜜外，将其它原料中药拣去杂质和粉尘后，按照质量份比共研为极细末待用；
B、按照传统制备中药蜜丸剂的方法，将研磨好的极细末药物过筛后，放入无菌室中的专用药器中拌均，然后制备成蜜丸剂（其水蜜丸的粒度为：5.0mm-5.1mm），继而晒干，瓶装密封备用。
一种治疗过敏性鼻炎的丸剂药物及其制备方法，其特征在于，所述服用方法为：将制备好的蜜丸剂药物以每日三次服用，早中晚各服一次，给药量5g /次（小儿酌减），饭前服，服药7-15天，诸症消失，病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
黄芪，性味：甘、温，具有补气固表、利尿消肿、托毒排脓、敛疮生肌、生肌之功效，用于治疗气虚乏力、食少便溏、中气下陷、久泻脱肛、便血崩漏、表虚自汗、气虚水肿、痈疽难溃、久溃不敛、血虚痿黄、内热消渴，慢性肾炎蛋白尿、糖尿病；
茯苓，性味：甘、淡、平，具有利水药、渗湿利尿药之功效，用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊；
白术，性味：味苦、甘、性温，具有健脾益气、燥湿利水、止汗、安胎之功效，用于治疗脾气虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气虚自汗、胎动不安；
防风，性味：味辛、甘、性微温，具有祛风解表、胜湿止痛、止痉定搐之功效，用于治疗外感表证、风疹瘙痒、风湿痹痛、破伤风等病症；
紫苏梗，性味：味辛、性温，具有理气宽中、安胎、和血之功效，用于治疗脾胃气滞、脘腹痞满、胎气不和、水肿脚气、咯血吐衄；
银柴胡，性味：甘、性微寒，具有清虚热、除疳热之功效，用于治疗阴虚发热、骨蒸劳热、小儿疳积发热；
乌梅，性味：味酸、性平，具有敛肺止咳、涩肠止泻、止血、生津、安蛔之功效，用于治疗久咳、虚热烦渴、久疟、久泻、痢疾、便血、尿血、血崩、蛔厥腹痛、呕吐、钩虫病；
玄参，性味：苦咸、凉，具有滋阴，降火，除烦，解毒之功效，用于治疗热病伤阴、舌绎烦渴、发斑、骨蒸劳热、夜寐不宁、自汗盗汗、津伤便秘、吐血衄血、咽喉肿痛、痈肿、瘰疬、温毒发斑、目赤、白喉、疮毒等病症；
五味子，性味：酸、甘、温，具有收敛固涩、益气生津、补肾宁心之功效，用于治疗久泻不止、久咳虚喘、心悸、失眠、多梦、自汗、盗汗、津伤口渴、消渴、遗精、滑精；
蝉蜕，性味：味甘、咸、性凉，具有宣散风热、透疹利咽、退翳明目、祛风止痉之功效，用于治疗风热感冒、咽喉肿痛、咳嗽音哑、单板机疹不透、风疹瘙痒、目赤翳障、惊痫抽搐、破伤风；
辛夷，性味：辛、温，具有祛风，通窍之功效，用于治疗头痛、鼻渊、鼻塞不通、齿痛；
苍耳子，性味：甘、温，有毒，具有散风、止痛、祛湿，杀虫之功效，用于治疗风寒头痛、鼻渊、齿痛、风寒湿痹、四肢挛痛、疥癞、瘙痒；
白芷，性味：性温、味辛、气芳香、微苦，具有祛风湿、活血排脓、生肌止痛之功效，用于治疗头痛、牙痛、鼻渊、肠风痔漏、赤白带下、痈疽疮疡、皮肤瘙痒；
桔梗，性味：味苦、辛、性平，具有宣肺、祛痰、利咽、排脓之功效，用于治疗咳嗽痰多、咽喉肿痛、肺痈吐脓、胞满胁痛、痢疾腹痛、小便癃闭；
细辛，性味：辛、温，具有祛风，散寒，行水，开窍之功效，用于治疗风冷头痛、鼻渊、齿痛、痰饮咳逆、风湿痹痛；
白蒺藜，性味：苦、辛、平，具有平肝解郁、祛风明目之功效，用于治疗肝阳眩晕头痛、肝郁胁痛、风热头痛、目赤肿痛、皮肤瘙痒等症；
薄荷，性味：味辛、性凉，具有散风热、清头目、利咽喉、透疹、解郁之功效，用于治疗风热表证、头痛目赤、咽喉肿痛、麻疹不透、陷疹瘙痒、肝郁胁痛等症。
本发明药物是基于中医治疗过敏性鼻炎的辨病与辨证相结合的原则，从药理作用及其作用机制认为：就过敏性鼻炎一证，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述过敏性鼻炎的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个标本兼治的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗过敏性鼻炎的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪25g、茯苓13g、白术13g、防风10g、紫苏梗10g、银柴胡8g、乌梅6g、玄参20g、五味子13g、蝉蜕6g、辛夷12g、苍耳子13g、白芷10g、桔梗10g、细辛5g、白蒺藜10g、薄荷5g，蜂蜜适量。
实施例2：
一种治疗过敏性鼻炎的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪28g、茯苓14g、白术14g、防风11g、紫苏梗11g、银柴胡9g、乌梅7g、玄参22g、五味子14g、蝉蜕7g、辛夷13g、苍耳子14g、白芷11g、桔梗11g、细辛5.5g、白蒺藜11g、薄荷6g，蜂蜜适量。
实施例3：
一种治疗过敏性鼻炎的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪32g、茯苓16g、白术16g、防风12g、紫苏梗12g、银柴胡10g、乌梅8g、玄参25g、五味子16g、蝉蜕8g、辛夷15g、苍耳子16g、白芷12g、桔梗12g、细辛6g、白蒺藜12g、薄荷7g，蜂蜜适量。典型病例：
经临床诊断治疗过敏性鼻炎的患者共150例，年龄为7岁以上的80例，只有70例为7岁以下。150例患者中痊愈的143例，显效的7例，总有效率达100%。经治疗后，诸症消失，病获痊愈。

Claims (3)

1.一种治疗过敏性鼻炎的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪9～32g、茯苓10～16g、白术8～16g、防风5～12g、紫苏梗5～12g、银柴胡5～10g、乌梅4～8g、玄参15～25g、五味子3～16g、蝉蜕3～8g、辛夷5～15g、苍耳子8～16g、白芷3～12g、桔梗3～12g、细辛2～6g、白蒺藜6～12g、薄荷3～7g，蜂蜜适量。
2.根据权利要求1所述的治疗过敏性鼻炎的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪15～28g、茯苓11～14g、白术10～14g、防风8～11g、紫苏梗8～11g、银柴胡7～9g、乌梅5～7g、玄参18～22g、五味子8～14g、蝉蜕5～7g、辛夷8～13g、苍耳子10～14g、白芷8～11g、桔梗8～11g、细辛3～5.5g、白蒺藜8～11g、薄荷4～6g，蜂蜜适量。
3.根据权利要求1至2所述的治疗过敏性鼻炎的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄芪25g、茯苓13g、白术13g、防风10g、紫苏梗10g、银柴胡8g、乌梅6g、玄参20g、五味子13g、蝉蜕6g、辛夷12g、苍耳子13g、白芷10g、桔梗10g、细辛5g、白蒺藜10g、薄荷5g，蜂蜜适量。
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090318399A1 (en) * 2008-06-20 2009-12-24 Sinphar Pharmaceutical Co., Ltd. Pharmaceutical composition and extract of poria for treating a disease induced from immune disorder
CN105770405A (zh) * 2016-05-28 2016-07-20 成都风靡生物科技有限公司 一种用于治疗过敏性鼻炎的中药组合物及制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090318399A1 (en) * 2008-06-20 2009-12-24 Sinphar Pharmaceutical Co., Ltd. Pharmaceutical composition and extract of poria for treating a disease induced from immune disorder
CN105770405A (zh) * 2016-05-28 2016-07-20 成都风靡生物科技有限公司 一种用于治疗过敏性鼻炎的中药组合物及制备方法

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