CN106176911A - A kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING - Google Patents
A kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING Download PDFInfo
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- CN106176911A CN106176911A CN201610705282.4A CN201610705282A CN106176911A CN 106176911 A CN106176911 A CN 106176911A CN 201610705282 A CN201610705282 A CN 201610705282A CN 106176911 A CN106176911 A CN 106176911A
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- Prior art keywords
- radix glycyrrhizae
- lijunjing
- poultry
- compound medicine
- poultry compound
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
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- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
- Fodder In General (AREA)
Abstract
The present invention relates to a kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING, be made up of LIJUNJING and Radix Glycyrrhizae, the weight ratio of LIJUNJING and Radix Glycyrrhizae is 1:1 1:5.The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.The present invention possesses and provides the benefit that: proving through experimental study, LIJUNJING is used in combination with specific part by weight with Radix Glycyrrhizae, has synergism obvious, and curative effect is fast, low cost and other advantages.
Description
Technical field
The invention belongs to poultry compound medicine technical field, particularly relate to a kind of poultry containing Radix Glycyrrhizae and LIJUNJING with multiple
Side's medicine, the disease caused for treating poultry to be infected by colon bacillus.
Background technology
Radix Glycyrrhizae is pulse family Glycyrrhiza perennial herb, and the root and rhizome of Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, eliminates the phlegm
Many effects such as cough-relieving, relieving spasm to stop pain, the mediation property of medicine, raising animal body immunity.At present, the root and rhizome of Radix Glycyrrhizae frequently as in
Medical herbs feed additive, medicine source is enriched, is had no side effect in animal body, almost without residual, does not the most produce drug resistance, collects nutrition
Keep healthy, prevent disease, seasoning flavouring, promote Production of Livestock and Poultry and improve animal meat quality in one.Radix Glycyrrhizae root and rhizome is raised poultry
Feed additives not only has stimulating appetite, strengthening digestion, improve local flavor, function that growth promotion is fattened, and there is prevention and control
Treating the function of multiple livestock and poultry, research shows, adds Radix Glycyrrhizae and can promote growth of animals or poultry, eat for a long time in additive for farm animal feed
With making poultry fur light, domestic animal gets fat soon, and poultry egg laying is many.Radix Glycyrrhizae adds in the Chinese medicine fodder of prevention and treatment common diseases of chickens
When adding in agent application, have that prophylactic treatment is effective, without any side effects, raw material is easy to get, cheap advantage.Additionally,
Radix Glycyrrhizae root and rhizome can be additionally used in the poisoning of piglet furazolidone, domestic animal eats the poisoning of the animal such as toxic plant poisoning, pig mouldy cron poisoning by mistake
Rescue, rescued effect is preferable.Radix Glycyrrhizae root and rhizome can be used for the treatment and prevention of multiple livestock and poultry as veterinary medicine, and obtains
Extraordinary treatment and prevention effect.
After poultry are infected by colon bacillus, the multiple locations such as acute sepsis, peritonitis, hepatitis, pneumonia, enteritis can be caused
Severe infections, causes huge economic loss to livestock and poultry cultivation.LIJUNJING, norfloxacin, florfenicol etc. are to prevent and treat this type of disease
Sick conventional Western medicine, along with medication is more and more spread unchecked, its Resistant strain is the most, and drug cost is the most increasing, but controls
Therapeutic effect and drug resistance situation are not taken a turn for the better, and go from bad to worse on the contrary.
Through retrieval, do not inquire Radix Glycyrrhizae and LIJUNJING are combined for treat poultry by colon bacillus infect cause
The relevant report of disease.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING, and it is worked in coordination with
Effect is substantially, it is possible to eliminate the colon bacillus drug resistance to LIJUNJING, improves therapeutic effect.
For solving above technical problem, the present invention by the following technical solutions: a kind of poultry containing Radix Glycyrrhizae and LIJUNJING are used
Compound medicine, is made up of LIJUNJING and Radix Glycyrrhizae, and the weight ratio of LIJUNJING and Radix Glycyrrhizae is 1:1-1:5.
The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.
The present invention possesses and provides the benefit that: proving through experimental study, LIJUNJING joins with specific part by weight with Radix Glycyrrhizae
Closing and use, have synergism obvious, curative effect is fast, low cost and other advantages.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme and beneficial effect are described further, except Special Statement
Outward, Radix Glycyrrhizae weight of the present invention is the dry weight of Radix Glycyrrhizae.
One, the Radix Glycyrrhizae mensuration to the drug resistance elimination effect of LIJUNJING
1. assay method
It is the mixing medicine that 1:1,1:3,1:5,1:10,1:30,1:50 prepare Radix Glycyrrhizae and various Western medicine respectively according to weight ratio
Liquid；Choose the bacterial strain to Western medicine drug resistance as subjects, utilize plate dilution method to carry out Secondary Culture, measure each process medicinal liquid
MIC situation of change to Resistant strain；Set the Western medicine being not added with Radix Glycyrrhizae to compare as sun, if it is right as the moon to be not added with Radix Glycyrrhizae and Western medicine simultaneously
According to.
Above-mentioned process was cultivated for 4 generations the most continuously.
2. result of the test
After cultivating for 4 generations continuously, the process flat board of cloudy comparison is long bacterium, and other each medicaments and admixing medical solutions are for large intestine angstrom
The result statistics of the MIC of uncommon Salmonella is as shown in table 1:
As seen from the above table, when the weight ratio of LIJUNJING Yu Radix Glycyrrhizae is 1:1,1:3 and 1:5, LIJUNJING is to drug resistance large intestine angstrom
The minimal inhibitory concentration of uncommon Salmonella all reduces more than 32 times, it is seen then that drug resistance colon bacillus is obvious to the drug resistance of LIJUNJING
Reduce.
And when the weight ratio of LIJUNJING Yu Radix Glycyrrhizae is 1:10,1:30 and 1:50, LIJUNJING is to drug resistance colon bacillus
Minimal inhibitory concentration be not added with Radix Glycyrrhizae sun comparison compared with, there is no significant change.
Two, the experiment in vitro that LIJUNJING and Radix Glycyrrhizae are used in combination
It is 1:5 mixing by LIJUNJING and Radix Glycyrrhizae (powder) according to weight ratio, makes powder, as test group；Separately set LIJUNJING
Single dose and Radix Glycyrrhizae single dose as a control group 1 and matched group 2.
Subjects is the chicken group making a definite diagnosis and having infected E.coli from chickens disease.
Morbidity chicken group is divided into 3 groups of administrations.Test group is administered according to the addition of 1g/kg feedstuff, and matched group 1 uses LIJUNJING
Single dose is administered according to the addition of 0.2g/kg feedstuff, and matched group 2 Radix Glycyrrhizae single dose is administered according to the addition of 1g/kg feedstuff；Respectively
Organize equal SM 5 days.
Result of the test: the sick chicken feed intake of test group increased, without dead, after using 5 days, chicken group can fully recover；Comparison
Chicken group's great majority still wan of group 1, has the sick chicken death of 3%；Chicken group's great majority of matched group 2 are also still wans, have
The sick chicken death of 12%.
Claims (2)
1. one kind contains Radix Glycyrrhizae and the poultry compound medicine of LIJUNJING, it is characterised in that be made up of LIJUNJING and Radix Glycyrrhizae, LIJUNJING
It is 1:1-1:5 with the weight ratio of Radix Glycyrrhizae.
2. by the compound preparation become prepared by the poultry compound medicine described in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610705282.4A CN106176911A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610705282.4A CN106176911A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106176911A true CN106176911A (en) | 2016-12-07 |
Family
ID=57524216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610705282.4A Withdrawn CN106176911A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Radix Glycyrrhizae and LIJUNJING |
Country Status (1)
| Country | Link |
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| CN (1) | CN106176911A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961421A (en) * | 2014-05-14 | 2014-08-06 | 广西大学 | Compound medicine containing radix paeoniae rubra and mequindox for livestock and poultry |
| CN104367601A (en) * | 2014-11-12 | 2015-02-25 | 广西大学 | Compound medicine containing herba pteridis multifidae and mequindox for livestock and poultry |
| CN104435038A (en) * | 2014-11-07 | 2015-03-25 | 广西大学 | Balsamiferou blumea herb and mequindox containing compound medicine for livestock and poultry |
-
2016
- 2016-08-22 CN CN201610705282.4A patent/CN106176911A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961421A (en) * | 2014-05-14 | 2014-08-06 | 广西大学 | Compound medicine containing radix paeoniae rubra and mequindox for livestock and poultry |
| CN104435038A (en) * | 2014-11-07 | 2015-03-25 | 广西大学 | Balsamiferou blumea herb and mequindox containing compound medicine for livestock and poultry |
| CN104367601A (en) * | 2014-11-12 | 2015-02-25 | 广西大学 | Compound medicine containing herba pteridis multifidae and mequindox for livestock and poultry |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161207 |
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| WW01 | Invention patent application withdrawn after publication |