CN106164665A - 用于毛细管电泳的光学系统 - Google Patents

用于毛细管电泳的光学系统 Download PDF

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Publication number
CN106164665A
CN106164665A CN201580017012.8A CN201580017012A CN106164665A CN 106164665 A CN106164665 A CN 106164665A CN 201580017012 A CN201580017012 A CN 201580017012A CN 106164665 A CN106164665 A CN 106164665A
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China
Prior art keywords
capillary
capillaries
output beams
array
beams
Prior art date
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Pending
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CN201580017012.8A
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English (en)
Chinese (zh)
Inventor
凯文·马赫尔
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Life Technologies Corp
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Life Technologies Corp
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Priority to CN202211196912.1A priority Critical patent/CN115389599B/zh
Publication of CN106164665A publication Critical patent/CN106164665A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201580017012.8A 2014-03-07 2015-03-06 用于毛细管电泳的光学系统 Pending CN106164665A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211196912.1A CN115389599B (zh) 2014-03-07 2015-03-06 用于毛细管电泳的光学系统

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461949914P 2014-03-07 2014-03-07
US201461949961P 2014-03-07 2014-03-07
US61/949,914 2014-03-07
US61/949,961 2014-03-07
PCT/US2015/019280 WO2015134925A1 (en) 2014-03-07 2015-03-06 Optical system for capillary electrophoresis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202211196912.1A Division CN115389599B (zh) 2014-03-07 2015-03-06 用于毛细管电泳的光学系统

Publications (1)

Publication Number Publication Date
CN106164665A true CN106164665A (zh) 2016-11-23

Family

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Family Applications (2)

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CN201580017012.8A Pending CN106164665A (zh) 2014-03-07 2015-03-06 用于毛细管电泳的光学系统
CN202211196912.1A Active CN115389599B (zh) 2014-03-07 2015-03-06 用于毛细管电泳的光学系统

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Country Status (5)

Country Link
US (2) US11280759B2 (https=)
EP (2) EP4517318A3 (https=)
JP (1) JP6755188B2 (https=)
CN (2) CN106164665A (https=)
WO (1) WO2015134925A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105548325A (zh) * 2016-01-30 2016-05-04 福州大学 毛细管电泳转轴式液滴进样装置及其进样方法
CN110520721A (zh) * 2017-02-24 2019-11-29 生命技术公司 用于样品分离的光学系统和方法
CN114450586A (zh) * 2019-08-07 2022-05-06 生命技术公司 用于毛细管电泳的多毛细管光学检测系统
CN114460156A (zh) * 2017-02-24 2022-05-10 生命技术公司 毛细管电泳系统、相关装置和相关方法

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EP4517318A3 (en) * 2014-03-07 2025-03-26 Life Technologies Corporation Optical system for capillary electrophoresis
WO2015179098A1 (en) 2014-05-21 2015-11-26 Integenx Inc. Fluidic cartridge with valve mechanism
US10690627B2 (en) 2014-10-22 2020-06-23 IntegenX, Inc. Systems and methods for sample preparation, processing and analysis
CN105973859B (zh) * 2016-06-29 2019-01-29 山东科立森生物股份有限公司 一种毛细管电泳检测系统及检测方法
CN105973860B (zh) * 2016-06-29 2019-07-30 山东科立森生物股份有限公司 一种毛细管电泳检测系统及检测方法
CA3033203C (en) 2016-08-15 2025-02-04 University Of Tasmania SYSTEMS AND METHODS FOR DETECTION OF INORGANIC IONS
JP6685965B2 (ja) 2017-03-29 2020-04-22 株式会社日立ハイテク キャピラリ電気泳動装置および恒温槽
US10302295B2 (en) * 2017-10-18 2019-05-28 Rite-Hite Holding Corporation Illuminating fans for loading docks
US11222779B2 (en) * 2018-05-17 2022-01-11 GMJ Technologies, Inc. Apparatuses for optical and mass spectrometry detection
JP6971409B2 (ja) * 2018-09-03 2021-11-24 株式会社日立ハイテク キャピラリアレイユニット
WO2020190969A1 (en) * 2019-03-18 2020-09-24 Life Technologies Corporation Multi-capillary optical detection system
WO2022024368A1 (ja) * 2020-07-31 2022-02-03 株式会社日立ハイテク キャピラリ電気泳動装置
WO2022153571A1 (ja) * 2021-01-15 2022-07-21 エースバイオアナリシス株式会社 走査ユニット、システムおよび方法、ならびにマイクロカラム
US11733156B2 (en) * 2021-02-23 2023-08-22 Joseph R. Demers Semiconductor package for free-space coupling of radiation and method

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US20060176481A1 (en) * 2005-02-10 2006-08-10 Massachusetts Institute Of Technology End-column fluorescence detection for capillary array electrophoresis
US20070065344A1 (en) * 2001-12-19 2007-03-22 3M Innovative Properties Company And Applera Corporation Analytical device with lightguide illumination of capillary and microgroove arrays
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CN101105455A (zh) * 2007-07-04 2008-01-16 四川大学 激光诱导荧光检测器
JP2010078559A (ja) * 2008-09-29 2010-04-08 Sumitomo Electric Ind Ltd 蛍光分析装置および方法
CN102023146A (zh) * 2010-09-28 2011-04-20 上海理工大学 一种光学检测的电泳芯片及其电泳装置

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105548325A (zh) * 2016-01-30 2016-05-04 福州大学 毛细管电泳转轴式液滴进样装置及其进样方法
CN110520721A (zh) * 2017-02-24 2019-11-29 生命技术公司 用于样品分离的光学系统和方法
CN114460156A (zh) * 2017-02-24 2022-05-10 生命技术公司 毛细管电泳系统、相关装置和相关方法
US11860122B2 (en) 2017-02-24 2024-01-02 Life Technologies Corporation Optical systems and methods for sample separation
CN114450586A (zh) * 2019-08-07 2022-05-06 生命技术公司 用于毛细管电泳的多毛细管光学检测系统
US12209954B2 (en) 2019-08-07 2025-01-28 Life Technologies Corporation Multi-capillary optical detection system

Also Published As

Publication number Publication date
EP4517318A3 (en) 2025-03-26
JP6755188B2 (ja) 2020-09-16
US11280759B2 (en) 2022-03-22
US20220244218A1 (en) 2022-08-04
EP3114469A1 (en) 2017-01-11
US20170016853A1 (en) 2017-01-19
CN115389599A (zh) 2022-11-25
WO2015134925A1 (en) 2015-09-11
JP2017507342A (ja) 2017-03-16
EP3114469B1 (en) 2024-11-20
CN115389599B (zh) 2025-10-28
EP4517318A2 (en) 2025-03-05

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