CN106140347B - A kind of water-bath for preparing NMR water mould detection sample - Google Patents

A kind of water-bath for preparing NMR water mould detection sample Download PDF

Info

Publication number
CN106140347B
CN106140347B CN201610620981.9A CN201610620981A CN106140347B CN 106140347 B CN106140347 B CN 106140347B CN 201610620981 A CN201610620981 A CN 201610620981A CN 106140347 B CN106140347 B CN 106140347B
Authority
CN
China
Prior art keywords
bath
water
temperature
relay
inner bag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610620981.9A
Other languages
Chinese (zh)
Other versions
CN106140347A (en
Inventor
李晓南
刘国强
李士强
夏正武
张超
李艳红
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Electrical Engineering of CAS
Original Assignee
Institute of Electrical Engineering of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Electrical Engineering of CAS filed Critical Institute of Electrical Engineering of CAS
Priority to CN201610620981.9A priority Critical patent/CN106140347B/en
Publication of CN106140347A publication Critical patent/CN106140347A/en
Application granted granted Critical
Publication of CN106140347B publication Critical patent/CN106140347B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/02Water baths; Sand baths; Air baths
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00Mixers with rotating receptacles
    • B01F29/30Mixing the contents of individual packages or containers, e.g. by rotating tins or bottles
    • B01F29/32Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor
    • B01F29/321Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor of test-tubes or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F35/92Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/50Clamping means, tongs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44Sample treatment involving radiation, e.g. heat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F2035/99Heating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

A kind of water-bath for preparing NMR water mould detection sample, its inner bag (10) and Resistant heating band (7) are located in water-bath (1), and Resistant heating band (7) is enclosed in the outer surface of inner bag (10).Bottom in inner bag (10) is equipped with temperature sensor (3) and temperature control instrument (4), described temperature sensor (3) is arranged on inner bag (10) bottom, is connected with temperature control instrument (4);Relay (5), motor (8) and DC power source adapter (6) are installed in water-bath;Temperature control instrument (4) is connected with the main switching control of relay (5);The both ends of relay (5) sub-control switch are connected with DC power source adapter (6) and Resistant heating band (7) respectively;Clip (9) clamping detects the test tube (2) of sample built with nuclear-magnetism, and the bottom of test tube (2) is inserted vertically into the water-bath liquid of inner bag (10) loading;The output end of motor (8) is connected with clip (9).

Description

A kind of water-bath for preparing NMR water mould detection sample
Technical field
The present invention relates to a kind of water-bath prepared for nuclear magnetic resonance sample.
Background technology
At present, known water-bath is for heating detected solution sample, promoting what the solute in solution fully dissolved.Often Accelerate solute dissolving or have to the method that sample stirs:A magnetic particle is put into the solution, and mixer puts burning The chassis interior of cup includes coil, and passing to alternating current makes magnetic particle rotation, so as to drive liquid to do eddying motion, reaches solute and stirs Mix uniform purpose.But some solution examples may corrode or pollute magnetic particle, cleaning, the maintenance of magnetic particle are influenceed And follow-up use.
The content of the invention
In order to overcome the shortcomings that solute inconvenience sometimes is put into magnetic particle in existing water-bath sample dissolution, the present invention proposes one Kind prepares the water-bath of nuclear magnetic resonance sample.The present invention, may be dirty without cleaning without toward foreign object is put into sample solution The magnetic particle or other function sundries of dye.Compared with current shaking table class water-bath, the present invention can make the dissolved efficiency of solute more It is high.
Water-bath of the present invention includes inner bag, Resistant heating band and clamping device.
Described inner bag and Resistant heating band are located in water-bath, and Resistant heating band is enclosed in the outer surface of inner bag. The bottom of water-bath inner bag is equipped with temperature sensor.One relay is installed, relay includes one among the bottom of water-bath Individual main switching control and a sub-control switch, control the turn-on and turn-off of heated current.The bottom of water-bath is also equipped with one Individual temperature control instrument, the temperature control instrument are connected with the main switching control of relay, output main control signal to relay. The opening or closure of the main control signal control sub-control switch, i.e. sub-control switch are same with the action of main switching control Step acts, and main switching control is opened sub-control switch and opened, and main switching control closure then drives sub-control switch also to close.It is described The both ends of relay sub-control switch are connected with DC power source adapter and Resistant heating band respectively.Resistant heating band, after Electrical equipment and DC power source adapter form a series loop.
The clamping device includes the clip and motor of holding test tubes.The clip of holding test tubes is clamped in the interposition of test tube Put, test tube is inserted vertically into the bath solution of water-bath inner bag loading built with copper sulfate solution, the bottom of the test tube.Electricity The output end of machine is connected with clip.Motor and DC power source adapter are located in water-bath, and relay also is located in water-bath.
The temperature sensor is mounted in the bottom of water-bath inner bag, measures the temperature of bath solution in inner bag, temperature in real time Control instrument is connected with temperature sensor.When solution temperature is less than design temperature, at such as 40 degrees Celsius, temperature control instrument output One switching signal to relay, relay main switching control is closed so that sub-control switch is also closed, then dc source is adapted to Device is connected with Resistant heating band, and heating tape starts to the bath solution heating in inner bag, solution heating.When temperature sensor is examined When measuring bath solution temperature higher than 40 degrees Celsius, temperature value is reached temperature control instrument, temperature control instrument stops output Switching signal, relay main switching control disconnect, and sub-control switch also disconnects, DC power source adapter and Resistant heating band it Between path be disconnected, heating tape stops giving inner bag heating, bath solution continues and surrounding environment does energy exchange and at a temperature of Drop.When temperature 40 degree Celsius of the temperature again below setting, in temperature sensor, temperature control instrument, relay, direct current Under the interaction of source adapter and heating tape, retriggered heated water bath solution.In whole nuclear magnetic resonance sample preparation process In, heating and temperature-fall period go round and begin again.When preparing NMR water apperance product, clip clamping is equipped with the nuclear-magnetism not being completely dissolved Detection sample copper sulfate solution test tube be placed in the bath solution of water-bath inner bag, test tube by clamping device motor driven Spin is done to rotate.As the nuclear-magnetism detection sample copper sulfate solution in test tube is heated to specified temp, then solution bottom Copper sulphate precipitate also accelerate to dissolve.
Water-bath of the present invention is connected after 220V AC powers, and the motor of clamping device starts running, and is driven on water-bath The clip of side makes clamped test tube spin motion.Bath solution is pure water.While connecting mains supply, the temperature passes The temperature of bath solution in sensor detection water-bath, when the temperature of bath solution is less than the temperature set, such as 40 degrees Celsius, Temperature control instrument outputs signal to relay, and relay main switching control and sub-control switch sequentially turn on, the direct current of series connection Power supply adaptor forms loop with heating tape and started working, and heating tape starts to warm up, and is heated to bath solution in pot, and then give Test tube kernel Magnetic testi sample heats, i.e., copper-bath heats.When fluid temperature is higher than 40 degrees Celsius in water-bath, temperature Sensor exports actual temperature signal to temperature control instrument in real time, and the temperature control instrument exports a signal to relay again Device, relay shut-off, heating tape disconnect with DC power source adapter, stop heating.
The present invention can avoid the foreign objects such as stirring magnetic particle from being placed in solution, be compared with shaking table class shaking bath pot, the present invention Dissolved efficiency it is higher.
Brief description of the drawings
The structure chart of Fig. 1 instant water-baths of nuclear magnetic resonance spin formula solute of the present invention.
In figure:1 water-bath, 2 test tubes, 3 temperature sensors, 4 temperature control instruments, 5 relays, 6 DC power source adapters, 7 Resistant heating bands, 8 motors, 9 clips, 10 inner bags.
Embodiment
The present invention is further described with reference to the accompanying drawings and examples.
As shown in figure 1, water-bath 1 of the present invention is built with inner bag 10 and Resistant heating band 7.Inner bag 10 is located at water-bath 1 Inside, Resistant heating band 7 is enclosed in the outer surface of inner bag 10.The bottom of inner bag 10 is equipped with temperature sensor 3.Water-bath 1 Bottom among a relay 5 is installed, relay 5 includes a main switching control and a sub-control switch, control plus The turn-on and turn-off of thermocurrent.The bottom of water-bath is also equipped with a temperature control instrument 4, the temperature control instrument 4 and after The main switching control of electrical equipment 5 is connected, output main control signal to relay 5.The main control signal control sub-control switch Open or closure, i.e. sub-control switch with the action of main switching control synchronization action, main switching control is opened sub-control and opened Close and open, main switching control closure then drives sub-control switch also to close.The relay sub-control switch is fitted with dc source Orchestration is connected with Resistant heating band 7.Resistant heating band 7, relay 5 and power supply adaptor 6 form a series loop.Folder Holding mechanism includes the clip 9 and motor 8 of holding test tubes 2, and clip 9 is clamped in the centre position of test tube 2, and motor 8 is located at water-bath The interior, side of Resistant heating band 7, the output end of motor 8 are connected with clip 9.
Water-bath 1 is connected after 220V AC powers, and motor 8 starts running, and drives the clip 9 of top holding test tubes dynamic Make, clip 9 accordingly drives and carries out spin motion by folder test tube.While switching on power, the temperature sensor 3 detects water-bath The temperature of water-bath liquid in 1, when less than 40 degrees Celsius of the temperature of setting, temperature control instrument 4 exports a signal to relay Device 5, relay 5 turn on, and power supply adaptor 6 and the tandem working of Resistant heating band 7, Resistant heating band 7 start to warm up, and feed water Water-bath liquid heats in bath 1, and then gives the detection sample copper sulfate solution heating of invisible spectro nuclear-magnetism.When liquid in water-bath 1 When temperature is higher than 40 degrees Celsius, temperature sensor 3 exports a heat alarm to temperature control instrument 4, the temperature control Instrument 4 exports a signal to relay 5, relay 5 and turned off again, and Resistant heating band 7 disconnects with DC power source adapter, stops Only heat.
The magnetic resonance detection sample is copper sulfate solution.In order to effectively facilitate copper sulphate solute in water it is uniformly fast Dissolve fastly, carrying nuclear-magnetism detection sample test tube be inserted vertically into water-bath water-bath after, under the drive of clamping device, institute State test tube and do at the uniform velocity spin and rotate, after continuing for some time, under heated and centripetal motion collective effect, reach dissolving, The purpose of nuclear magnetic resonance experiment sample preparation.

Claims (3)

1. a kind of water-bath for preparing NMR water mould detection sample, described water-bath (1) include inner bag (10), resistance wire Heating tape (7), described inner bag (10) and Resistant heating band (7) are located in water-bath (1), it is characterised in that:Described water Bath (1) also includes clamping device;
Described Resistant heating band (7) is enclosed in the outer surface of inner bag (10);Bottom in inner bag (10) is equipped with TEMP Device (3);Relay (5) is installed, relay (5) includes a main switching control and a secondary control among the bottom in water-bath System switch, control the turn-on and turn-off of heated current;The bottom of water-bath (1) is also equipped with temperature control instrument (4), the temperature Control instrument (4) is connected with the main switching control of relay (5), output main control signal to relay (5);The relay (5) both ends of sub-control switch are connected with DC power source adapter (6) and Resistant heating band (7) respectively, Resistant heating Band (7), relay (5) and DC power source adapter (6) form a series loop;Described temperature sensor (3) is arranged on Inner bag (10) bottom, is connected with temperature control instrument (4);
The clamping device includes the clip (9) and motor (8) of holding test tubes;Clip (9) is clamped in the interposition of test tube (2) Put, test tube (2) detects sample copper sulfate solution built with nuclear-magnetism;The bottom of the test tube (2) is inserted vertically into water-bath inner bag (10) in the water-bath liquid loaded;The output end of motor (8) is connected with clip (9);Motor (8) and DC power source adapter (6) In water-bath (1).
2. according to the water-bath for preparing NMR water mould detection sample described in claim 1, it is characterised in that:Described examination Pipe (2) is inserted vertically into the water-bath liquid of water-bath (1), and under the drive of clamping device, the test tube (2) does at the uniform velocity spinning It is dynamic.
3. according to the water-bath for preparing NMR water mould detection sample described in claim 1, it is characterised in that:Described temperature Spend the temperature that sensor (3) measures bath solution in inner bag (10) in real time;When solution temperature is less than design temperature, temperature control Instrument (4) exports a switching signal to relay (5), the main switching control of relay (5) and closed so that sub-control switchs Closure, DC power source adapter (6) are connected with Resistant heating band (7), and Resistant heating band (7) starts in inner bag (10) Bath solution heats, solution heating;When temperature sensor (3) detects that bath solution temperature is higher than design temperature, temperature Value, which is transmitted to temperature control instrument (4), temperature control instrument (4), stops output switching signal, the main switching control of relay (5) Disconnect, sub-control switch is also disconnected, and the path between DC power source adapter (6) and Resistant heating band (7) is disconnected, resistance Silk heating tape (7) stops heating to inner bag (10), and bath solution continues and surrounding environment does energy exchange and temperature declines;In temperature Spend under sensor, temperature control instrument, relay, DC power source adapter and the interaction of heating tape, retriggered heating Bath solution;In whole nuclear magnetic resonance sample preparation process, heating and temperature-fall period go round and begin again.
CN201610620981.9A 2016-08-01 2016-08-01 A kind of water-bath for preparing NMR water mould detection sample Active CN106140347B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610620981.9A CN106140347B (en) 2016-08-01 2016-08-01 A kind of water-bath for preparing NMR water mould detection sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610620981.9A CN106140347B (en) 2016-08-01 2016-08-01 A kind of water-bath for preparing NMR water mould detection sample

Publications (2)

Publication Number Publication Date
CN106140347A CN106140347A (en) 2016-11-23
CN106140347B true CN106140347B (en) 2017-12-15

Family

ID=57327842

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610620981.9A Active CN106140347B (en) 2016-08-01 2016-08-01 A kind of water-bath for preparing NMR water mould detection sample

Country Status (1)

Country Link
CN (1) CN106140347B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108254239A (en) * 2018-03-20 2018-07-06 苏州铭恒金属科技有限公司 A kind of thermostat and processing method for the detection of aluminium alloy macrostructure
CN110346192B (en) * 2019-06-27 2020-04-17 青岛海洋地质研究所 Pretreatment method for testing volatile elements in marine combustible ice sediment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101184360B1 (en) * 2010-10-01 2012-09-20 한일과학산업 주식회사 Stirring apparatus of thermostat
CN201897559U (en) * 2010-11-30 2011-07-13 常州豪邦纳米科技涂料有限公司 Constant-temperature rotary viscosimeter
CN202570226U (en) * 2012-05-22 2012-12-05 刘庆祥 Thermostatic water bath
CN204220178U (en) * 2014-11-17 2015-03-25 郑志凌 A kind of rotatable alternating temperature rack for test tube
CN204865893U (en) * 2015-08-13 2015-12-16 宁波大学 Liftable rotatory test tube water bath device
CN204952941U (en) * 2015-09-14 2016-01-13 苏州众人健身器材有限公司 Modular stirring vibration constant temperature heating water bath device

Also Published As

Publication number Publication date
CN106140347A (en) 2016-11-23

Similar Documents

Publication Publication Date Title
CN106140347B (en) A kind of water-bath for preparing NMR water mould detection sample
CN205539196U (en) Resistance measuring device
CN201978764U (en) Thermostatic water bath kettle
CN110052188A (en) A kind of pharmacy solid reagent dissolver
CN205749358U (en) Oil bath experimental provision
CN208742396U (en) Mixing device is used in a kind of processing of electromagnetic type dairy products
CN204347654U (en) Scientific research and testing Intelligent Constant Temperature Controlling System
CN104862156A (en) Soap making machine and soap making method
CN208389941U (en) A kind of medicament agitating device
EP2361686A2 (en) Dissolution testing apparatus for pharmaceutical preparations
CN201969382U (en) Transformer oil separation device
CN107684461A (en) A kind of Orthopedic operation clamp cleaning equipment
CN208721523U (en) A kind of precoated sand collapsibility detection device
CN203782128U (en) Full-automatic soapmaking device
CN208405453U (en) A kind of clinical laboratory's equipment cleaning sterilizing device
CN208334008U (en) A kind of intelligence quick sample processing instrument
CN206793708U (en) A kind of intelligent visual constant water bath box
CN208984123U (en) A kind of storage-type electric water heater security appliance performance experimental rig
CN207764220U (en) A kind of medical inspection section test detecting equipment
CN208293003U (en) cell recovery device
CN207494923U (en) Motor pulls out shaft device to wheel and belt pulley electric heating
CN206627348U (en) A kind of oil bath digestion instrument
CN206270145U (en) A kind of laboratory lubricating oil oil sample Preparation equipment
CN110694532A (en) Mixed heating device for pharmacology experiments
CN109521297A (en) A kind of welding electrical contact heat-resisting quantity test device

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant