CN106138242A - Medicine for the treatment of hysteromyoma and preparation method thereof - Google Patents
Medicine for the treatment of hysteromyoma and preparation method thereof Download PDFInfo
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- CN106138242A CN106138242A CN201610711670.3A CN201610711670A CN106138242A CN 106138242 A CN106138242 A CN 106138242A CN 201610711670 A CN201610711670 A CN 201610711670A CN 106138242 A CN106138242 A CN 106138242A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The present invention relates to a kind of medicine treating hysteromyoma and preparation method thereof, raw material components by weight, including: polygonaceae plant raw material 30 80 parts and Herba Euphorbiae Humifusae 10 30 parts；Wherein, described polygonaceae plant raw material is leaf or the aerial stem of plant or leaf and the mixture of the aerial stem of plant.The preparation method of the medicine for the treatment of hysteromyoma, comprises the following steps: mixed with other components by polygonaceae plant raw material, puts into and soak 30 80 minutes in decocting medicine pot；Said medicine component after soaking makes to boil with high heat again the heating of exchange of notes fire；Product after being heated by described slow fire filters, it is thus achieved that the medicine soup for the treatment of hysteromyoma.Medicine for the treatment of hysteromyoma that the present invention provides and preparation method thereof, can effectively reduce the estrogen level of patient, reduce the volume of hysteromyoma；Meanwhile, the medicine property of medicine of the treatment hysteromyoma that the present invention provides is gentle, it is not necessary to distinguishes drug component according to strict indication, has general applicability.
Description
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of medicine treating hysteromyoma and preparation method thereof.
Background technology
Hysteromyoma is the multiple disease of gynecological, is the modal benign tumor of female reproductive system, shows as abdominal part pain more
Bitterly, abdominal mass and metrorrhagia, more serious causing is infertile, secondary anemia, habitual abortion and premature labor etc..Provide according to statistics
Material shows, the prevalence of Female in child bearing period hysteromyoma reaches 25%.Currently mainly treatment means is still based on operative therapy, but by
In operation itself traumatic, the ultimacy of total hysterectomy, myomectomy can recurrent etc. make patient at heart, physiology
All suffer pressure, have impact on the physical and mental health of women, because hysteromyoma TCM Therapy receives the extensive concern of medical circle.
And data according to statistics, the incidence rate the most about 1/300 that cancerates of hysteromyoma, the most not necessarily will excision.Meeting the tendency and
In raw Drug therapy, treat the common medicine mifepristone of hysteromyoma at present, it is possible to reduce estrogen content in the patient,
Promote tumor body to reduce, but this medicine has many untoward reaction, and this medicine of life-time service can damage hepatic and renal function.Other tradition
Chinese medicine also has the curative effect of certain treatment hysteromyoma, but such Chinese medicine needs strict determining according to patient's indication
Add that medicine, such as such Chinese medicine to need to distinguish menstrual phase and usual phase；Or need differentiation mass formed by blood stasis severe one, the stagnation of QI tight
Severe one, cold coagulation person, heat in blood person or insufficiency of vital energy and blood person etc.；Thus cause the differentiation of symptoms and signs for classification of syndrome of such Chinese medicine and treatment standard less
Unified, medication classification difference is relatively big, and the most objective tightly, this leverages its scientific and reliability, and then affects it
Promote and use.
Summary of the invention
For defect of the prior art, the invention provides a kind of medicine treating hysteromyoma and preparation method thereof,
Effectively to reduce the estrogen level of patient, reduce the volume of hysteromyoma；Meanwhile, the treatment hysteromyoma that the present invention provides
The medicine property of medicine is gentle, it is not necessary to distinguishes drug component according to strict indication, has general applicability.
First aspect, the present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including knotweed
Section's plant material 30-80 part and Herba Euphorbiae Humifusae 10-30 part；Wherein, described polygonaceae plant raw material be leaf or the aerial stem of plant or leaf and
The mixture of the aerial stem of plant.
By the polygonaceae plant raw material of 30-80 part and the Herba Euphorbiae Humifusae of 10-30 part with the use of, wherein, polygonaceae plant raw material is
Leaf or the aerial stem of plant or leaf and the mixture of the aerial stem of plant, can effectively reduce the estrogen level of patient, reduce hysteromyoma
Volume；Herba Euphorbiae Humifusae is based on its abundant chemical composition, such as flavonoid, triterpenes, Coumarins, sterols, tannin and phenolic acid
The compounds such as class have multiple pharmacological effect, and they are many is used for treating dermatosis, bacillary dysentery, enteritis, viral as antifungal drug
In the diseases such as hepatitis；But in the present invention, by the polygonaceae plant raw material of the Herba Euphorbiae Humifusae of 10-30 part and 30-80 part with the use of, can
To be efficiently used for the medicine of preparation treatment hysteromyoma, this medicine is used for treating hysteromyoma, can effectively reduce patient's
Estrogen level and reduce the volume of hysteromyoma.And, compared with the medicine being traditionally used for treatment hysteromyoma, traditional drugs
Thing needs to distinguish menstrual phase and usual phase；Or need to distinguish mass formed by blood stasis severe one, stagnation of QI severe patient, cold coagulation person, heat in blood person or QI and blood not
Foot person etc.；Thus causing the differentiation of symptoms and signs for classification of syndrome of such Chinese medicine and treatment standard the most unified, medication classification difference is relatively big, and not
Enough the most objective tightly this leverages its scientific and reliability, and then affects it and promote and use.And the present invention by 10-
What the polygonaceae plant raw material of the Herba Euphorbiae Humifusae of 30 parts and 30-80 part formed is used for treating the medicine of hysteromyoma in use,
The property of medicine is gentle, it is not necessary to distinguishes drug component according to strict indication, has general applicability.
In the further embodiment of the present invention, raw material components by weight, also includes: Rhizoma Curcumae 15-25 part, Ramulus Cinnamomi
5-8 part, Flos Carthami 5-10 part, Radix Salviae Miltiorrhizae 8-15 part；Rhizoma Sparganii 8-10 part, Radix Paeoniae Rubra 3-10 part and Sargassum 2-8 part.
In the further embodiment of the present invention, raw material components is by weight, preferred: polygonaceae plant raw material 50
Part, Herba Euphorbiae Humifusae 15 parts, Rhizoma Curcumae 18 parts, Ramulus Cinnamomi 6 parts, 8 parts of Flos Carthami, Radix Salviae Miltiorrhizae 12 parts, Rhizoma Sparganii 9 parts, Radix Paeoniae Rubra 7 parts and Sargassum 5 parts.
In the further embodiment of the present invention, raw material components is by weight, preferred: polygonaceae plant raw material 35
Part, Herba Euphorbiae Humifusae 25 parts, Rhizoma Curcumae 21 parts, Ramulus Cinnamomi 7 parts, 6 parts of Flos Carthami, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Sparganii 8 parts, Radix Paeoniae Rubra 5 parts and Sargassum 8 parts.
In the further embodiment of the present invention, described polygonaceae plant raw material is Pteroxygonum giraldii, convolution knotweed, tooth wing knotweed, Corii Bovis seu Bubali
Disappear one or more in knotweed, Radix Polygoni aubertii, arrow leaf knotweed or Herba Polygoni cymosi.
Second aspect, the present invention provides the preparation method of a kind of medicine treating hysteromyoma, comprises the following steps: take every
The polygonaceae plant raw material that year lunar calendar gathers in mid-July to mid-August, cleans, dries rear cutting to 3-30 mesh；According to claim
The component ratio of medicine of the treatment hysteromyoma of any one of 1 to claim 5, by the polygonaceae plant raw material after above-mentioned cutting with
Other components mix, and put into and soak in decocting medicine pot 30-80 minute；Said medicine component after soaking makes to boil with high heat
5-8 minute, then exchange of notes fire heat 30-50 minute；Product after being heated by described slow fire filters, it is thus achieved that the medicine for the treatment of hysteromyoma
Soup.
Take the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, and only choose the leaf of polygonaceae plant raw material
And the aerial stem of plant, it is impossible to include rhizome；Then leaf and the aerial stem of plant of the polygonaceae plant raw material chosen are removed earth, after clear water is cleaned
Dry；The leaf of the polygonaceae plant raw material after drying and aerial stem of plant cutting, to 3-30 mesh, form polygonaceae plant raw material；Then will power
1-weighs the component ratio of the medicine of the treatment hysteromyoma of 5 any one, by the polygonaceae plant raw material after above-mentioned cutting and other groups
Divide mixing, put into and decocting medicine pot is soaked 30-80 minute, so that the effective ingredient in each raw material components leaches；Soak time
More than 80 minutes, the active substance in raw material components can be caused oxidized, and soak time was less than 30 minutes, can cause in raw material
Active component can not fully leach；Said medicine component after soaking makes to boil the heating of rear exchange of notes fire with high heat, first uses force
Fire boils 5-8 minute, i.e. promotes the dissolubility of each raw material components to increase under conditions of heating up rapidly, promotes more effectively group
Divide dissolution；Then exchange of notes fire heats 30-50 minute, slow fire, the most weak fire, fireless fire, and temperature rises relatively slow, and moisture evaporates
The slowest, thus be more beneficial for the fried of effective ingredient in each raw material components；Product after being heated by slow fire filters, and removes medicine soup.
The preparation method of the medicine of the treatment hysteromyoma of present invention offer is provided, efficiency can be prepared and reduce the estrogen water of patient
Flat and reduce the medicine of hysteromyoma of volume of hysteromyoma；And the medicine property of medicine gentleness prepared, it is not necessary to according to strict
Indication distinguishes drug component, has general applicability.
In the further embodiment of the present invention, after the heating of described exchange of notes fire, described by after the heating of described slow fire
Product also includes before filtering: the product cooling after being heated by described slow fire.
In the further embodiment of the present invention, by the leaf of polygonaceae plant raw material and aerial stem of plant cutting to 25 mesh.
In the further embodiment of the present invention, the time that described intense fire boils is 6 minutes.
In the further embodiment of the present invention, the time of described slow fire heating is 38 minutes.
Accompanying drawing explanation
Fig. 1 is the flow chart of the preparation method of the medicine of the treatment hysteromyoma in the embodiment of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the embodiment of technical solution of the present invention is described in detail.Following example are only used for
Technical scheme is more clearly described, is therefore only used as example, and the protection model of the present invention can not be limited with this
Enclose.
The present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including polygonaceae plant raw material
30-80 part, Herba Euphorbiae Humifusae 10-30 part；Wherein, described polygonaceae plant raw material is leaf or the aerial stem of plant, or leaf and the aerial stem of plant is mixed
Compound.By the polygonaceae plant raw material of 30-80 part and the Herba Euphorbiae Humifusae of 10-30 part with the use of, can effectively reduce the female of patient and swash
Element level, reduces the volume of hysteromyoma；Herba Euphorbiae Humifusae is based on its abundant chemical composition, such as flavonoid, triterpenes, coumarin
The compounds such as class, sterols, tannin and phenolic acids have multiple pharmacological effect, and how it is used for treating skin as antifungal drug
In the diseases such as disease, bacillary dysentery, enteritis, viral hepatitis；But in the present invention, by the Polygonaceae of the Herba Euphorbiae Humifusae of 10-30 part Yu 30-80 part
The leaf of plant material and the aerial stem of plant with the use of, the medicine of preparation treatment hysteromyoma can be efficiently used for, this medicine is used for
Treatment hysteromyoma, can effectively reduce the estrogen level of patient and reduce the volume of hysteromyoma.And, with traditional use
Medicine in treatment hysteromyoma is compared, and conventional medicament needs to distinguish menstrual phase and usual phase；Or need to distinguish mass formed by blood stasis severe one, gas
Stagnant severe patient, cold coagulation person, heat in blood person or insufficiency of vital energy and blood person etc.；Thus cause differentiation of symptoms and signs for classification of syndrome and the treatment standard of such Chinese medicine
The most unified, medication classification difference is relatively big, and the most objective tightly, this leverages its scientific and reliability, Jin Erying
Ring it promote and use.And the present invention by the leaf of the Herba Euphorbiae Humifusae of 10-30 part and the polygonaceae plant raw material of 30-80 part and the aerial stem of plant
Composition for treating the medicine of hysteromyoma in use, the property of medicine is gentle, it is not necessary to distinguish medicine according to strict indication
Thing component, has general applicability.
Preferably, raw material components by weight, also includes: Rhizoma Curcumae 15-25 part, Ramulus Cinnamomi 5-8 part, Flos Carthami 5-10 part, red
Ginseng 8-15 part；Rhizoma Sparganii 8-10 part, Radix Paeoniae Rubra 3-10 part and Sargassum 2-8 part.Rhizoma Curcumae can be regulated the flow of vital energy promoting the circulation of blood, and blood circulation promoting and blood stasis dispelling, Ramulus Cinnamomi can activate yang
Cold expelling, temperatureization aqueous vapor, gas in tonification, pancake is rushed inverse, and the logical stasis of blood is invigorated blood circulation；Flos Carthami can regulating menstruation, can invigorate blood circulation latus rectum, eliminating stasis to stop pain；Invigorate blood circulation
Blood stasis dispelling, regulating QI to relieve pain；Radix Salviae Miltiorrhizae energy blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, removing heat from blood is subsided a swelling；Rhizoma Sparganii can be regulated the flow of vital energy promoting the circulation of blood, blood circulation promoting and blood stasis dispelling；Radix Paeoniae Rubra energy
Clearing away heat and cooling blood, eliminating stasis to stop pain；Sargassum can be reduced phlegm detumescence, hard masses softening and resolving；Inventor finds through lot of experiments: pressed by above medicine
The medicine prepared after the mixing of weight portion compatibility is than being used alone the leaf of polygonaceae plant raw material and the aerial stem of plant and Herba Euphorbiae Humifusae obtains
Medicine has more preferable effect in terms for the treatment of hysteromyoma, can more effectively reduce the estrogen level of patient and reduce uterus
The volume of muscular tumor.
Preferably, polygonaceae plant raw material is Pteroxygonum giraldii, convolution knotweed, tooth wing knotweed, cynanchum auriculatum Royle ex Wight knotweed, Radix Polygoni aubertii, arrow leaf knotweed or thick stick plate
One or more in returning.
It addition, the medicine of the treatment hysteromyoma for the present invention, the treatment of the specialized designs of the present invention preparation present invention
The preparation method of the medicine of hysteromyoma:
Fig. 1 is the flow chart of the preparation method of the medicine of the treatment hysteromyoma in the embodiment of the present invention, as it is shown in figure 1,
The preparation method of the medicine of the treatment hysteromyoma that the present invention provides, comprises the following steps:
S101: take the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, cleans, dries rear cutting to 3-
30 mesh.
Take leaf or the aerial stem of plant of the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, or leaf and ground
The mixture of upper stem, and only choose the aerial stem of plant of polygonaceae plant, it is impossible to include rhizome；Then by the polygonaceae plant raw material chosen
Leaf and the aerial stem of plant remove earth, and clear water dries after cleaning；The leaf of the polygonaceae plant raw material after drying and aerial stem of plant chopping；By knotweed
The leaf of section's plant material and aerial stem of plant cutting are to 3-30 mesh, and in raw material components, the decocting rate of effective ingredient has with the degree of cutting
The biggest relation, only when by the leaf of polygonaceae plant raw material and aerial stem of plant cutting to 3-30 mesh, could be maximally effective and as far as possible
Effective ingredient in many leaves by polygonaceae plant raw material and the aerial stem of plant leaches.
S102: according to the component ratio of the medicine treating hysteromyoma of any one of claim 1 to claim 5, will
Polygonaceae plant raw material after above-mentioned cutting mixes with other components, puts into and soaks in decocting medicine pot 30-80 minute.At decocting medicine pot
In soak 30-80 minute so that effective ingredient in each raw material components leaches, soak time, more than 80 minutes, can cause
Active substance in raw material components is oxidized, and soak time was less than 30 minutes, and the active component in raw material can be caused not fill
Sub-dip goes out.
S103: the said medicine component after soaking makes to boil with high heat 5-8 minute, then exchange of notes fire heats 30-50 minute.
Said medicine component after soaking makes to boil with high heat the heating of rear exchange of notes fire, first boils 5-8 minute with high heat, i.e.
Promote the dissolubility of each raw material components to increase under conditions of heating up rapidly, promote more active component dissolution；Then the exchange of notes
Fire heating, slow fire, the most weak fire, fireless fire, temperature rises relatively slow, and moisture evaporates the slowest, thus is more beneficial for each former
In material component, effective ingredient is fried；The time keeping intense fire to boil is 5-8 minute, it is ensured that the hysteromyoma medicine prepared
Thing drug effect is higher；Boil laggard style of writing fire heating in 5-8 minute at intense fire, and the time keeping slow fire to heat is 30-50 minute, can
So that the effective ingredient in raw material components is the most fried, so that the medicine of the treatment hysteromyoma prepared more effectively drops
The estrogen level of low patient and reduce the medicine of hysteromyoma of volume of hysteromyoma.Product after being heated by slow fire is cold
But, the effective ingredient in raw material components can be made further to leach, further ensure that drug effect.
S104: the product after being heated by described slow fire filters, it is thus achieved that the medicine soup for the treatment of hysteromyoma.Described slow fire is heated
After product filter, remove medicinal residues, medicine soup part be obtain treatment hysteromyoma medicine.
Illustrate below in conjunction with detailed description of the invention:
Embodiment one
The present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including polygonaceae plant raw material
50 parts and Herba Euphorbiae Humifusae 15 parts.
By above-mentioned raw materials component, use the preparation method of the medicine of the treatment hysteromyoma of present invention offer, preparation treatment
The medicine of hysteromyoma:
Take leaf and the aerial stem of plant of the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, after cleaning, drying
Cutting is to 5 mesh；50 parts of polygonaceae plant raw materials and 15 parts of Herba Euphorbiae Humifusaes are put into and soaked 50 minutes in decocting medicine pot；By described immersion
Drug component after 50 minutes makes to boil 6 minutes with high heat；Then heat 30 minutes with slow fire；Product after described slow fire is heated
Thing filters, it is thus achieved that the medicine soup for the treatment of hysteromyoma.
Embodiment two
The present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including polygonaceae plant raw material
50 parts, Herba Euphorbiae Humifusae 15 parts, Rhizoma Curcumae 18 parts, Ramulus Cinnamomi 6 parts, 8 parts of Flos Carthami, Radix Salviae Miltiorrhizae 12 parts；Rhizoma Sparganii 9 parts, Radix Paeoniae Rubra 7 parts and Sargassum 5 parts.
By above-mentioned raw materials component, use the preparation method of the medicine of the treatment hysteromyoma of present invention offer, preparation treatment
The medicine of hysteromyoma:
Take leaf and the aerial stem of plant of the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, after cleaning, drying
Cutting is to 25 mesh；By 50 parts of polygonaceae plant raw materials, 15 parts of Herba Euphorbiae Humifusaes, 18 parts of Rhizoma Curcumae, 6 parts of Ramulus Cinnamomi, 8 parts of Flos Carthamis, 12 parts of Radix Salviae Miltiorrhizaes；9
Part Rhizoma Sparganii, 7 parts of Radix Paeoniae Rubra and 5 portions of Sargassums are put into and are soaked 50 minutes in decocting medicine pot；By the medicine group after described immersion 50 minutes
Divide and make to boil 6 minutes with high heat；Then heat 38 minutes with slow fire；Product after being heated by described slow fire filters, it is thus achieved that treatment
The medicine soup of hysteromyoma.
Embodiment three
The present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including polygonaceae plant raw material
35 parts, Herba Euphorbiae Humifusae 25 parts, Rhizoma Curcumae 21 parts, Ramulus Cinnamomi 7 parts, 6 parts of Flos Carthami, Radix Salviae Miltiorrhizae 10 parts；Rhizoma Sparganii 8 parts, Radix Paeoniae Rubra 5 parts and Sargassum 8 parts.
By above-mentioned raw materials component, use the preparation method of the medicine of the treatment hysteromyoma of present invention offer, preparation treatment
The medicine of hysteromyoma:
Take leaf and the aerial stem of plant of the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, after cleaning, drying
Cutting is to 25 mesh；By 35 parts of polygonaceae plant raw materials, 25 parts of Herba Euphorbiae Humifusaes, 21 parts of Rhizoma Curcumae, 7 parts of Ramulus Cinnamomi, 6 parts of Flos Carthamis, 10 parts of Radix Salviae Miltiorrhizaes；8
Part Rhizoma Sparganii, 5 parts of Radix Paeoniae Rubra and 8 portions of Sargassums are put into and are soaked 50 minutes in decocting medicine pot；By the medicine group after described immersion 50 minutes
Divide and make to boil 6 minutes with high heat；Then heat 38 minutes with slow fire；Product after being heated by described slow fire filters, it is thus achieved that treatment
The medicine soup of hysteromyoma.
Embodiment four
The present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including polygonaceae plant raw material
30 parts, Herba Euphorbiae Humifusae 10 parts, Rhizoma Curcumae 15 parts, Ramulus Cinnamomi 5 parts, 5 parts of Flos Carthami, Radix Salviae Miltiorrhizae 8 parts；Rhizoma Sparganii 9 parts, Radix Paeoniae Rubra 3 parts and Sargassum 2 parts.
By above-mentioned raw materials component, use the preparation method of the medicine of the treatment hysteromyoma of present invention offer, preparation treatment
The medicine of hysteromyoma:
Take leaf and the aerial stem of plant of the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, after cleaning, drying
Cutting is to 30 mesh；By 30 parts of polygonaceae plant raw materials, 10 parts of Herba Euphorbiae Humifusaes, 15 parts of Rhizoma Curcumae, 5 parts of Ramulus Cinnamomi, 5 parts of Flos Carthamis, 8 Radix Salviae Miltiorrhizaes；9 part three
Rib, 3 parts of Radix Paeoniae Rubra and 2 portions of Sargassums are put into and are soaked 30 minutes in decocting medicine pot；Drug component after described immersion 30 minutes is made
Boil 5 minutes with high heat；Then heat 50 minutes with slow fire；Product after being heated by described slow fire filters, it is thus achieved that treatment uterus
The medicine soup of muscular tumor.
Embodiment five
The present invention provides a kind of medicine treating hysteromyoma, raw material components by weight, including polygonaceae plant raw material
80 parts, Herba Euphorbiae Humifusae 30 parts, Rhizoma Curcumae 25 parts, Ramulus Cinnamomi 8 parts, 10 parts of Flos Carthami, Radix Salviae Miltiorrhizae 15 parts；Rhizoma Sparganii 10 parts, Radix Paeoniae Rubra 10 parts and Sargassum 8
Part.
By above-mentioned raw materials component, use the preparation method of the medicine of the treatment hysteromyoma of present invention offer, preparation treatment
The medicine of hysteromyoma:
Take leaf and the aerial stem of plant of the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, after cleaning, drying
Cutting is to 20 mesh；By 80 parts of polygonaceae plant raw materials, 30 parts of Herba Euphorbiae Humifusaes, 25 parts of Rhizoma Curcumae, 8 parts of Ramulus Cinnamomi, 10 parts of Flos Carthamis, 15 parts of Radix Salviae Miltiorrhizaes；9
Part Rhizoma Sparganii, 3 parts of Radix Paeoniae Rubra and 2 portions of Sargassums are put into and are soaked 80 minutes in decocting medicine pot；By the medicine group after described immersion 80 minutes
Divide and make to boil 8 minutes with high heat；Then heat 45 minutes with slow fire；Product cooling after slow fire is heated；Then after cooling down
Product filter, it is thus achieved that treatment hysteromyoma medicine soup.
The medicine soup embodiment of the present invention one to embodiment five obtained, the situation for treating hysteromyoma carries out system and comments
Valency:
Mode of specifically taking is: the medicine soup embodiment of the present invention one to embodiment five obtained, and point morning, noon and afternoon take for three times,
200ml to 300ml, three months courses for the treatment of, is applied particularly to 500 patients with uterin leiomyoma patients every time；Experiment finds, this Drug therapy
The effective percentage of hysteromyoma is up to 93%, and all has no side effect.
One, the detection of hysteromyoma volume
Observing clinical therapeutic efficacy, evaluate according to muscular tumor volume-diminished degree, concrete condition is as shown in table 1:
Effective: ultrasound diagnosis display hysteromyoma disappears, or volume-diminished more than 50%；Take a turn for the better: muscular tumor volume-diminished
25%～50%；Invalid: within muscular tumor volume-diminished 25%, patients symptomatic improves inconspicuous.Wherein, total effective rate=obvious effective rate
+ improvement rate.
Table 1 uses the mutation analysis of hysteromyoma volume after the Drug therapy of the present invention
Two, Hormone traits detection
Measure the hormonal readiness after patient treatment, with estradiol (E2), lutropin (LH), follicle stimulating hormone) (FSH) be
Representing, concrete condition is as shown in table 2.
Because clinical research shows, hysteromyoma has hormonal dependent, and increasing of estrogen is to cause hysteromyoma
The basic reason of continued propagation, estrogen in patient's muscular tumor tissue, progesterone level are apparently higher than its hetero-organization；Therefore, suffer from
In person's body, the minimizing of such estrogen content, can promote reducing of hysteromyoma；Therefore commonly use the detection case of these several hormones
Evaluation criterion as treatment hysteromyoma:
Table 2 uses the Hormone traits situation of the Drug therapy of the present invention
Certainly, situation about enumerating except embodiment one to embodiment five, the parts by weight of other raw material components, intense fire boil
Time, slow fire heating time, other mesh numbers of chopping are also possible.Simply enumerate in embodiment one to embodiment five
In the case of, it is more that the estrogen level of patient reduces, and it is more that the volume of hysteromyoma also reduces.And, applicant passes through
Substantial amounts of experiment finds, uses the special parameter in embodiment two and the weight portion compatibility of embodiment three and preparation process, preparation
The effective percentage of the hysteromyoma medicine gone out is higher, and it is more that the estrogen level of patient reduces, and the volume of hysteromyoma also reduces
More.
In the medicine of traditional treatment hysteromyoma, the effective percentage of GUIZHI FULING JIAONANG is about 85%；Therefore, the controlling of the present invention
The medicine effective percentage treating hysteromyoma is higher than conventional GUIZHI FULING JIAONANG, and in terms of hormone reduction, the hormone water of the present invention
Low more of pancake, i.e. effect is better than GUIZHI FULING JIAONANG.
Additionally, the polygonaceae plant raw material that the present invention provides, it is also possible to directly take after mixing it with hot water, take half a year more than, it is possible to
To reduce the estrogen level of patient, reduce the volume of hysteromyoma.
Medicine for the treatment of hysteromyoma of the present invention and preparation method thereof, can effectively reduce the estrogen level of patient, contracting
The volume of little hysteromyoma；Meanwhile, the medicine property of medicine of the treatment hysteromyoma that the present invention provides is gentle, it is not necessary to fit according to strict
Answer disease to distinguish drug component, there is general applicability.
In the description of this specification, reference term " embodiment ", " some embodiments ", " example ", " specifically show
Example " or the description of " some examples " etc. means to combine this embodiment or example describes specific features, structure, material or spy
Point is contained at least one embodiment or the example of the present invention.In this manual, to the schematic representation of above-mentioned term not
Identical embodiment or example must be directed to.And, the specific features of description, structure, material or feature can be in office
One or more embodiments or example combine in an appropriate manner.Additionally, in the case of the most conflicting, the skill of this area
The feature of the different embodiments described in this specification or example and different embodiment or example can be tied by art personnel
Close and combination.
Although above it has been shown and described that embodiments of the invention, it is to be understood that above-described embodiment is example
Property, it is impossible to being interpreted as limitation of the present invention, those of ordinary skill in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, revises, replaces and modification.
Claims (10)
1. the medicine treating hysteromyoma, it is characterised in that raw material components by weight, including:
Polygonaceae plant raw material 30-80 part and Herba Euphorbiae Humifusae 10-30 part；
Wherein, described polygonaceae plant raw material is leaf or the aerial stem of plant, or leaf and the mixture of the aerial stem of plant.
The medicine for the treatment of hysteromyoma the most according to claim 1, it is characterised in that raw material components by weight, is gone back
Including:
Rhizoma Curcumae 15-25 part, Ramulus Cinnamomi 5-8 part, Flos Carthami 5-10 part, Radix Salviae Miltiorrhizae 8-15 part, Rhizoma Sparganii 8-10 part, Radix Paeoniae Rubra 3-10 part and Sargassum 2-
8 parts.
The medicine for the treatment of hysteromyoma the most according to claim 2, it is characterised in that raw material components by weight, wraps
Include:
Polygonaceae plant raw material 50 parts, Herba Euphorbiae Humifusae 15 parts, Rhizoma Curcumae 18 parts, Ramulus Cinnamomi 6 parts, 8 parts of Flos Carthami, Radix Salviae Miltiorrhizae 12 parts, Rhizoma Sparganii 9 parts, red
Chinese herbaceous peony 7 parts and Sargassum 5 parts.
The medicine for the treatment of hysteromyoma the most according to claim 2, it is characterised in that raw material components by weight, wraps
Include:
Polygonaceae plant raw material 35 parts, Herba Euphorbiae Humifusae 25 parts, Rhizoma Curcumae 21 parts, Ramulus Cinnamomi 7 parts, 6 parts of Flos Carthami, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Sparganii 8 parts, red
Chinese herbaceous peony 5 parts and Sargassum 8 parts.
5. according to the medicine of the treatment hysteromyoma described in any one of claim 1-4, it is characterised in that
Described polygonaceae plant raw material is in Pteroxygonum giraldii, convolution knotweed, tooth wing knotweed, cynanchum auriculatum Royle ex Wight knotweed, Radix Polygoni aubertii, arrow leaf knotweed and Herba Polygoni cymosi
Plant or multiple.
6. the preparation method of the medicine treating hysteromyoma, it is characterised in that comprise the following steps:
Take the polygonaceae plant raw material that annual lunar calendar gathers in mid-July to mid-August, clean, dry rear cutting to 3-30 mesh；
According to the component ratio of the medicine treating hysteromyoma of any one of claim 1 to claim 5, after above-mentioned cutting
Polygonaceae plant raw material mix with other components, put into and decocting medicine pot soaked 30-80 minute；
Said medicine component after soaking makes to boil with high heat 5-8 minute, then exchange of notes fire heats 30-50 minute；
Product after being heated by described slow fire filters, it is thus achieved that the medicine soup for the treatment of hysteromyoma.
The preparation method of the medicine for the treatment of hysteromyoma the most according to claim 6, it is characterised in that:
The described exchange of notes fire heating after, described by described slow fire heat after product filter before further comprise the steps of: described literary composition
Product cooling after fire heating.
The preparation method of the medicine for the treatment of hysteromyoma the most according to claim 6, it is characterised in that:
By the leaf of polygonaceae plant raw material and aerial stem of plant cutting to 25 mesh.
The preparation method of the medicine for the treatment of hysteromyoma the most according to claim 6, it is characterised in that:
The time soaked is 50 minutes.
The preparation method of the medicine for the treatment of hysteromyoma the most according to claim 6, it is characterised in that:
The time that described intense fire boils is 6 minutes；The time of described slow fire heating is 38 minutes.
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| CN113082185A (en) * | 2021-04-22 | 2021-07-09 | 胡巧生 | Oral product for relieving swelling and preventing cancer and preparation method thereof |
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