CN106119109A - A kind of pharmaceutical cell culture system - Google Patents
A kind of pharmaceutical cell culture system Download PDFInfo
- Publication number
- CN106119109A CN106119109A CN201610499261.1A CN201610499261A CN106119109A CN 106119109 A CN106119109 A CN 106119109A CN 201610499261 A CN201610499261 A CN 201610499261A CN 106119109 A CN106119109 A CN 106119109A
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- Prior art keywords
- casing
- shutter
- cell culture
- plate device
- thermal insulation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/58—Reaction vessels connected in series or in parallel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/04—Seals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of pharmaceutical cell culture system, including cultivating casing, vertical column fixing device, column, add thermoelectric plate device, heating wire, shutter, shutter motor unit, culture medium, culture chamber, rotating mechanism, thermal insulation board.Beneficial effects of the present invention is to be divided into different cultivation regions by cultivating casing, maximally utilize the volume of casing, by the drive mechanism arranged, easily cell culture environment can be adjusted, the blinds apparatus arranged, can uniformly add thermoelectric plate device transmit heat and air quantity, thus avoid heat overheated or air quantity concentrate growth of microorganism is had adverse effect on.
Description
Technical field
The present invention relates to field of biological pharmacy, a kind of pharmaceutical cell culture system.
Background technology
Biological culture technigue is always a key areas of bio-pharmaceuticals, and microbial cultivation device is a kind of in microorganism
The wide variety of equipment in field such as, bio-pharmaceuticals and biomedicine.The biological object cultivated in microbial cultivation device
Difference, corresponding culture environment is the most different, and the control to culture apparatus requires the most different certainly.Train in microorganism
During Yanging, temperature is the deciding factor of growth of microorganism, is only in, when temperature, the tolerance model that optimum temperature is the narrowest
When enclosing interior, can be only achieved the most preferable and strong cell growth.The temperature-controlled process of existing microbiological incubator uses height
The conventional thermal switching technology of Low Temperature Wet wet heating testing case, i.e. beyond the mode such as active force forced air supply hot blast or cold wind are sent to
In culture medium, to reach cell culture medium refrigeration or the purpose heated.Forced air supply is often by growth on cell culture medium
Cell blows off, and cell growth has adverse effect on.Additionally for different microorganisms, the temperature strip that its growth needs is different
Part, the cultivation temperature in culture medium is the most different, if it is possible to realize being capable of different temperatures in a culture medium
Regulate simultaneously, will can be greatly increased the utilization rate of cell culture medium, at utmost utilize the volume of culture medium.
Summary of the invention
In order to make up the deficiencies in the prior art, the invention provides a kind of pharmaceutical cell culture system, that it changes
Heat-supplying mode in conventional cell base, by cell culture medium is divided into different cultivation modules, thus at utmost utilizes training
Support the volume of base.
The technical solution adopted for the present invention to solve the technical problems is: a kind of pharmaceutical cell culture system, including
Cultivate casing, vertical column fixing device, column, add thermoelectric plate device, heating wire, shutter, shutter motor unit, cultivate
Base, culture chamber, rotating mechanism, thermal insulation board.Described cultivation casing is for fully sealing structure, and its top is provided with the fixing dress of column
Putting, centre is provided with column, column is provided with and adds thermoelectric plate device, adds thermoelectric plate device and is fixed on cultivation casing, heating
Electroplax device lower end is provided with shutter, and shutter is fixed with cultivating casing by shutter motor unit, and hundred
Leaf window construction lower end is provided with culture medium, and culture medium is provided with culture chamber, and culture medium is fixed on rotating mechanism, drive mechanism
Being arranged on cultivation casing, drive mechanism lower end is provided with thermal insulation board, and thermal insulation board is fixed on cultivation casing.
As preferred technical scheme, the described thermoelectric plate device that adds is substantially sector structure, is divided into six parts, each
It is provided with the heating wire of different capacity in part, thus produces the heat of different requirement.
As preferred technical scheme, described shutter motor unit drives shutter to rotate, the BAIYE of rotation
Window homogenization can add the heat that thermoelectric plate device transmits.
As preferred technical scheme, described culture medium is fixed on rotating mechanism, and drive mechanism can turn around column
Dynamic, thus the heating wire of culture medium correspondence different capacity that will arrange on it, thus meet the different microorganisms requirement to temperature.
As preferred technical scheme, a kind of heat-barrier material of described thermal insulation board, it is possible to by whole cultivation casing
Being divided into different heating regions, being allowed to work alone is independent of each other.
As preferred technical scheme, described column is fixed on cultivation casing by vertical column fixing device, and passes through
Wear whole cultivation casing.
As preferred technical scheme, described cultivation casing can be divided into different region of cultivating by thermal insulation board, thus
Big degree utilizes the volume cultivating casing.
The invention have the benefit that and be divided into different cultivation regions by cultivating casing, maximally utilize the volume of casing,
By the drive mechanism arranged, in that context it may be convenient to cell culture environment is adjusted, the blinds apparatus of setting, it is possible to uniformly
Add thermoelectric plate device transmit heat and air quantity, thus avoid heat overheated or air quantity concentrate to growth of microorganism produce disadvantageous
Impact.
Accompanying drawing explanation
The present invention is further described with embodiment below in conjunction with the accompanying drawings.
Fig. 1 is the structural representation of the present invention;
Fig. 2 be the present invention add thermoelectric plate apparatus structure schematic diagram;
Fig. 3 is the structural representation of the culture chamber of the present invention;
In figure: 1. cultivate casing, 2. vertical column fixing device, 3. column, 4. add thermoelectric plate device, 5. heating wire, 6. BAIYE
Window construction, 7. shutter motor unit, 8. culture medium, 9. culture chamber, 10. rotating mechanism, 11 thermal insulation boards.
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and be easy to understand with effect, below knot
Conjunction is specifically illustrating, and the present invention is expanded on further.
As shown in Figure 1, Figure 2, Figure 3 shows, a kind of pharmaceutical cell culture system of the present invention, including cultivating casing 1,
Vertical column fixing device 2, column 3, add thermoelectric plate device 4, heating wire 5, shutter 6, shutter motor unit 7, culture medium
8, culture chamber 9, rotating mechanism 10, thermal insulation board 11.Described cultivation casing 1 is for fully sealing structure, and its top is provided with column
Fixing device 2, centre is provided with column 3, column 3 is provided with and adds thermoelectric plate device 4, adds thermoelectric plate device 4 and is fixed on cultivation
On casing 1, add thermoelectric plate device 4 lower end and be provided with shutter 6, shutter 6 by shutter motor unit 7 with
Cultivating casing 1 to fix, shutter 6 lower end is provided with culture medium 8, and culture medium 8 is provided with culture chamber 9, and culture medium 8 is solid
Being scheduled on rotating mechanism 10, drive mechanism 10 is arranged on cultivation casing 1, and drive mechanism 10 lower end is provided with thermal insulation board 11, every
Hot plate 11 is fixed on cultivation casing 1.
As preferred technical scheme, described adds thermoelectric plate device 4 substantially sector structure, is divided into six parts, often
It is provided with the heating wire 5 of different capacity in individual part, thus produces the heat of different requirement.
As preferred technical scheme, described shutter motor unit 7 drives shutter 6 to rotate, the hundred of rotation
Leaf window 6 homogenization can add the heat that thermoelectric plate device 4 transmits.
As preferred technical scheme, described culture medium 8 is fixed on rotating mechanism 10, and drive mechanism 10 can be around vertical
Post 3 rotates, thus by the heating wire 5 of corresponding for the culture medium 8 that arranges on it different capacity, thus meet different microorganisms to temperature
Requirement.
As preferred technical scheme, described a kind of heat-barrier material of thermal insulation board 11, it is possible to by whole incubator
Body 1 is divided into different heating regions, and being allowed to work alone is independent of each other.
As preferred technical scheme, described column 2 is fixed on cultivation casing 1 by vertical column fixing device 2, and
Run through whole cultivation casing 1.
As preferred technical scheme, described cultivation casing 1 can be divided into different region of cultivating by thermal insulation board 11, thus
At utmost utilize the volume cultivating casing 1.
Claims (4)
1. a pharmaceutical cell culture system, is primarily characterized in that: include cultivate casing, vertical column fixing device, column,
Add thermoelectric plate device, heating wire, shutter, shutter motor unit, culture medium, culture chamber, rotating mechanism, thermal insulation board.
Described cultivation casing is for fully sealing structure, and its top is provided with vertical column fixing device, and centre is provided with column, and column sets
It is equipped with and adds thermoelectric plate device, add thermoelectric plate device and be fixed on cultivation casing, add thermoelectric plate device lower end and be provided with shutter knot
Structure, shutter is fixed with cultivating casing by shutter motor unit, and shutter lower end is provided with culture medium, training
Supporting and be provided with culture chamber on base, culture medium is fixed on rotating mechanism, and drive mechanism is arranged on cultivation casing, under drive mechanism
End is provided with thermal insulation board, and thermal insulation board is fixed on cultivation casing.
A kind of pharmaceutical cell culture system the most according to claim 1, is primarily characterized in that: described adds thermoelectricity
Panel assembly is substantially sector structure, is divided into six parts, each part is provided with the heating wire of different capacity.
A kind of pharmaceutical cell culture system the most according to claim 1, is primarily characterized in that: described thermal insulation board
A kind of heat-barrier material, it is possible to whole cultivation casing is divided into different heating regions.
A kind of pharmaceutical cell culture system the most according to claim 1, is primarily characterized in that: described column leads to
Cross vertical column fixing device to be fixed on cultivation casing, and run through whole cultivation casing.
Priority Applications (1)
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CN201610499261.1A CN106119109A (en) | 2016-06-29 | 2016-06-29 | A kind of pharmaceutical cell culture system |
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CN201610499261.1A CN106119109A (en) | 2016-06-29 | 2016-06-29 | A kind of pharmaceutical cell culture system |
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CN106119109A true CN106119109A (en) | 2016-11-16 |
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CN201610499261.1A Pending CN106119109A (en) | 2016-06-29 | 2016-06-29 | A kind of pharmaceutical cell culture system |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106085816A (en) * | 2016-06-29 | 2016-11-09 | 安徽三彩工贸有限责任公司 | A kind of Portable cell incubator |
CN108485943A (en) * | 2018-03-19 | 2018-09-04 | 吴娜 | A kind of cancer related gene mutation high-sensitivity detecting method |
Citations (8)
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CN2523496Y (en) * | 2001-09-12 | 2002-12-04 | 顺德市顺达电脑厂有限公司 | Incubators |
US20030186429A1 (en) * | 2002-03-26 | 2003-10-02 | Becton Dickinson And Company | Reversible petri dish |
CN201678666U (en) * | 2010-04-15 | 2010-12-22 | 浙江理工大学 | Drawer type microorganism incubator |
CN202610230U (en) * | 2012-05-29 | 2012-12-19 | 陕西科技大学 | Culture dish with separable culture area |
CN103374522A (en) * | 2012-04-16 | 2013-10-30 | 北京华慧天行科技有限公司 | Temperature and humidity guaranteeing device of biological culture box |
CN203866304U (en) * | 2014-05-07 | 2014-10-08 | 深圳市安美信生物医药科技有限公司 | Microbiological incubator |
CN204111761U (en) * | 2014-07-11 | 2015-01-21 | 陈康 | A kind of medical science incubator |
CN106085816A (en) * | 2016-06-29 | 2016-11-09 | 安徽三彩工贸有限责任公司 | A kind of Portable cell incubator |
-
2016
- 2016-06-29 CN CN201610499261.1A patent/CN106119109A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2523496Y (en) * | 2001-09-12 | 2002-12-04 | 顺德市顺达电脑厂有限公司 | Incubators |
US20030186429A1 (en) * | 2002-03-26 | 2003-10-02 | Becton Dickinson And Company | Reversible petri dish |
CN201678666U (en) * | 2010-04-15 | 2010-12-22 | 浙江理工大学 | Drawer type microorganism incubator |
CN103374522A (en) * | 2012-04-16 | 2013-10-30 | 北京华慧天行科技有限公司 | Temperature and humidity guaranteeing device of biological culture box |
CN202610230U (en) * | 2012-05-29 | 2012-12-19 | 陕西科技大学 | Culture dish with separable culture area |
CN203866304U (en) * | 2014-05-07 | 2014-10-08 | 深圳市安美信生物医药科技有限公司 | Microbiological incubator |
CN204111761U (en) * | 2014-07-11 | 2015-01-21 | 陈康 | A kind of medical science incubator |
CN106085816A (en) * | 2016-06-29 | 2016-11-09 | 安徽三彩工贸有限责任公司 | A kind of Portable cell incubator |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106085816A (en) * | 2016-06-29 | 2016-11-09 | 安徽三彩工贸有限责任公司 | A kind of Portable cell incubator |
CN108485943A (en) * | 2018-03-19 | 2018-09-04 | 吴娜 | A kind of cancer related gene mutation high-sensitivity detecting method |
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Application publication date: 20161116 |