CN106075152A - A kind of fatigue alleviating, the maca composition of raising energy - Google Patents

A kind of fatigue alleviating, the maca composition of raising energy Download PDF

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CN106075152A
CN106075152A CN201610621307.2A CN201610621307A CN106075152A CN 106075152 A CN106075152 A CN 106075152A CN 201610621307 A CN201610621307 A CN 201610621307A CN 106075152 A CN106075152 A CN 106075152A
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fatigue
rhizoma polygonati
adjuvant
maca composition
raw material
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代鹏飞
陈雪敏
余元涛
张超
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WUHAN HUASHITE INDUSTRIAL BIOTECHNOLOGY DEVELOPMENT Co Ltd
Beijing Tianwu Four Biological Technology Co Ltd
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WUHAN HUASHITE INDUSTRIAL BIOTECHNOLOGY DEVELOPMENT Co Ltd
Beijing Tianwu Four Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention discloses a kind of fatigue alleviating, the maca composition of raising energy, being made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 30 ~ 60%, Radix Ginseng 1 ~ 6%, Rhizoma Polygonati 3 ~ 15%, Rhizoma Polygonati Odorati 1 ~ 10%, Fructus Rubi 3 ~ 12%, Poria 2 ~ 10%, Fructus Gardeniae 0.5 ~ 5%, green tea 0.5 ~ 6%, Herba Lophatheri 0.5 ~ 7%, Radix Glycyrrhizae 1 ~ 12%, surplus is adjuvant.Mutual compatibility between each raw material components of the present invention, it is possible to fatigue alleviating, improves energy, enhancing body motion function, has warm nature conditioning, positive element QI invigorating, replenishing QI to invigorate the spleen, effect of nourishing the liver and kidney.The beneficial effects of the present invention is: the fatigue causing a variety of causes and sub-health population have obvious resisting fatigue effect;Simple process is easy, and production cost is low, it is simple to industrialized production;Can make multiple dosage form, taking convenience as required, the property of medicine is gentle, and raw material is natural food materials, has no side effect.

Description

A kind of fatigue alleviating, the maca composition of raising energy
Technical field
The invention belongs to field of health care products, be specifically related to a kind of Lepidinm meyenii Walp combination with fatigue alleviating, raising energy effect Thing.
Background technology
In modern society, along with rhythm of life is gradually accelerated, the stress of people, psychological burden are more and more heavier, thus The muscle power overdraw brought, falls, and causes physical fatigue, tired mind, hypomnesis, work efficiency drop, loses Dormancy dreaminess, immunity degradation etc., modern medicine is referred to as chronic fatigue syndrome.Strenuous exercise or short-term are not had enough sleep The fatigue caused belongs to acute fatigue, if acute fatigue can not eliminate after occurring in time, it will gradually accumulate, ultimately resulted in Degree fatigue, affects endocrine and immunity, and then produces a series of subhealth symptom.Research shows, tired and male's sexual Go down and also have close relationship, owing to muscle is the most tired out, or because the mental property caused by melancholy, uneasiness, anxiety, anxiety etc. is tired Exhausted, body can be upset and run system normally, disturb physiological function, suppress the nervus centralis relevant to physiological function, reduce and hang down The promoting sexual gland hormone of body and the secretory volume of androgen;Meanwhile, fatigue can produce lipid peroxide, and this lipid can be direct Cause biomembranous damage, in the course of time, physiological system is caused irreversible pathological lesion, ultimately results in sexual dysfunction Occur.
Along with the reinforcement of people's health care consciousness, various anti-fatigue products arise at the historic moment, wherein Chinese medicine series products natural with it, The advantage such as safe and free of toxic and side effects, is increasingly subject to the concern of people.It is flooded with various, uneven in the market Anti-fatigue medicament, effect is different, but most of curative effect is inconspicuous, takes effect slowly, cures the symptoms, not the disease, it is impossible to fundamentally solve Problem.
Summary of the invention
For above-mentioned weak point of the prior art, it is an object of the invention to provide one to alleviate for people tired Labor, improves energy, enhancing body motion function, has warm nature conditioning, positive element QI invigorating, replenishing QI to invigorate the spleen, the agate of nourishing the liver and kidney effect Coffee compositions.
The above-mentioned purpose of the present invention is achieved by the following technical programs.
A kind of fatigue alleviating, improve the maca composition of energy, including the raw material of following percentage by weight: Lepidinm meyenii Walp 30 ~ 60%, Radix Ginseng 1 ~ 6%, Rhizoma Polygonati 3 ~ 15%, Rhizoma Polygonati Odorati 1 ~ 10%, Fructus Rubi 3 ~ 12%, Poria 2 ~ 10%, Fructus Gardeniae 0.5 ~ 5%, green tea 0.5 ~ 6%, Herba Lophatheri 0.5 ~ 7%, Radix Glycyrrhizae 1 ~ 12%, surplus is adjuvant.
Modern Chinese medicine is thought, fatigue is a name of disease, has its etiology and pathogenesis, is commonly encountered diseases, frequently-occurring disease clinically, is necessary The new sick kind paid attention to, is attributed to subhealth state category, relates to the vital organs of the human body, mainly based on spleen, liver, kidney.Its disease QI and blood deficiency tired, Weakness of the spleen and stomach, deficiency of kidney-essence, yin asthenia generating intrinsic heat, control suitable qi and blood tonifying, invigorating the spleen and regulating the stomach, kidney tonifying, essence replenishing, nourishing YIN and clearing away heat.The present invention according to The medicine foods such as theory of Chinese medical science reasonable compatibility Lepidinm meyenii Walp, Radix Ginseng, Rhizoma Polygonati, Rhizoma Polygonati Odorati, Fructus Rubi, Poria, Fructus Gardeniae, green tea, Herba Lophatheri, Radix Glycyrrhizae are same Source medical material, energy is with mending, and significantly enhances Lepidinm meyenii Walp resisting fatigue, effect of raising energy.Lepidinm meyenii Walp, Radix Ginseng kidney tonifying in the present invention Controlling nocturnal emission with astringent drugs, strongly invigorating primordial QI, promote the production of body fluid Gu de-, and Fructus Alpiniae Oxyphyllae of calming the nerves is monarch drug;Rhizoma Polygonati, Rhizoma Polygonati Odorati, Fructus Rubi, Poria nourishing kidney yin are ministerial drug;Cape jasmine Son, green tea, Herba Lophatheri are adjuvant drug, break through warm-dryness syndrome;Radix Glycyrrhizae for making medicine, coordinating the actions of various ingredients in a prescription, play benefiting QI for activating blood circulation altogether, invigorating the liver and kidney effect, use In fatigue alleviating, improve energy.Only above-mentioned each component is rationally compounded according to percentage by weight of the present invention, ability Reach the purpose of mutual Synergistic.
Lepidinm meyenii Walp (Maca), has another name called Maca, originates in the mountain area, Andean, South America of height above sea level 3500 ~ 4500 m, is mainly distributed In Peru, for Cruciferae Lepidium plant.Anemia, pulmonary tuberculosis, sterile and tired is treated as one by American Indian A kind of medicine.China is starting introduction and plantation Lepidinm meyenii Walp, mainly based on the ground such as Yunnan and Tibet at the beginning of 21 century.Research table Bright, Lepidinm meyenii Walp can improve sexual dysfunction, improves memory and the ability of study, anxiety reduction;Human body energy can be regulated disappear The functional disorder of consumption, metabolism disorder, central nervous system and hormonal system, plays effect of fatigue alleviating, physical strength reinforcing;Agate Coffee extract can strengthen motility of sperm, the hormone secretion in regulation serum, reduces blood pressure.The physiologically active of Lepidinm meyenii Walp and its Chemical composition has close relationship.Lepidinm meyenii Walp contains rich in protein, aminoacid, reducing sugar, mineral, unsaturated fatty acids The anti-fatigue nutrient thing such as acid, especially taurine, mineral zinc, branched-chain amino acid (leucine, valine, isoleucine) Matter, they play an important role in eliminating motorium fatigue and organism fatigue.Additionally, the secondary metabolites of Lepidinm meyenii Walp mainly has Macamide, Lepidinm meyenii Walp alkene, glucosinolate, sterol and alkaloid etc., wherein, macamide and Lepidinm meyenii Walp alkene be in Lepidinm meyenii Walp peculiar become Point, it is the core substance realizing Lepidinm meyenii Walp anti-fatigue effect.
Radix Ginseng can effectively strengthen nervus centralis, reach with all worries set aside with fixed attention, the effect such as allaying tiredness, memory reinforcing, can fit For having a sleepless night, the symptom such as irritated, hypomnesis and senile dementia.
Rhizoma Polygonati has a boosting qi and nourishing yin, spleen invigorating, lung moistening, the function of kidney tonifying, for weakness of the spleen and stomach, and fatigue and asthenia, xerostomia lack of appetite, Deficiency of the lung cough caused by dryness, asthenia of essence and blood, the disease that interior-heat is quenched one's thirst.And, Rhizoma Polygonati also has blood pressure lowering and hypoglycemic activity, can increase crown Blood flow volume, landing hypolipemia and delay the effect such as atherosclerosis.
Rhizoma Polygonati Odorati, sweet in the mouth is put down, is attached to the lung and stomach meridians.Having nourishing YIN and moistening the lung, effect of nourishing the stomach to promote the production of body fluid, for cough caused by dryness, chronic cough, heat The sick cloudy liquid consumption dry throat and mouth of wound, interior-heat are quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizziness, muscle arteries and veins spasm and pain.
Fructus Rubi has tonifying the kidney to consolidate the essence, effect of the supporing yang enuresis, except for diseases such as impotence and premature ejaculation, seminal emission, enuresis due to deficiency of the kidney Treatment.
Poria, property is sweet, light, flat, enters the heart, spleen, kidney channel, has eliminating dampness by diuresis diuresis, closes stomach spleen invigorating, mind tranquilizing and the heart calming, enhancing body Immunity and hypoglycemic effect.Mild in medicine property and, dampness removing and do not hinder healthy energy, it is adaptable to edema oliguria, insufficiency of the spleen lack of appetite, the mind is not Peace, the disease such as insomnia and dreamful sleep, can be used for deficiency of both the heart and spleen, the uneasy all cards of heart kidney, and for spleen YANG deficiency, the seminal emission that QI collapse caused by exhaustion of QI of the spleen and kidney essence is let out.
Fructus Gardeniae, bitter in the mouth cold in nature, GUIXIN, liver, lung, stomach warp, have and let out fire relieving restlessness, clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body, main Control calentura restlessness of asrhenia type and insomnia, jaundice, quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, the disease such as pathopyretic ulcer.
Green tea have refresh oneself clear away heart-fire, clearing away summer-heat, eliminate indigestion and phlegm, fat-reducing slimming, the relieving restlessness that clears away heart-fire, removing toxic substances relieving alcoholic intoxication, only promote the production of body fluid The pharmacological actions such as yearningly, pathogenic fire reducing improving eyesight, dysentery relieving dehumidifying.Caffeine in green tea can promote human central nervous excited, contributes to waking up Brain is refreshed oneself, and strengthens corticocerebral process of excitation, plays the effect that benefit of refreshing oneself is thought, cleared away heart-fire.Containing potent antioxidant in green tea And vitamin C, not only can be with the free radical in purged body, moreover it is possible to secret out of the hormone of antagonism tension pressure, therefore have alleviation Tired effect.
Herba Lophatheri has refrigerant, antipyretic, diuresis and the effect hastened parturition.Cure mainly disease heat, cough with dyspnea, haematemesis, pyretic toxicity wind, only in the heart Quench one's thirst, press borax poison, expectorant, control fanatical unhappiness, apoplectic aphasia in silence, wind syndrome of head, spasmolytic are throbbed with fear bitterly, pestilence fan is vexed.
Radix Glycyrrhizae, property sugariness is flat, GUIXIN, lung, spleen, stomach warp.Radix Glycyrrhizae has invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, eliminating fire and detoxication, emergency Many effects such as pain relieving, coordinating the actions of various ingredients in a prescription.It is mainly used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, Extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity is with strong.
According to the above-mentioned Formulation Implementation present invention, it is thus achieved that provide the benefit that: the present invention is based on above-mentioned natural plants specific Effect and pharmaceutical value, use natural plants and natural product, combined with theory of medicine by traditional health-preserving method, be conceived to Fatigue alleviating, improve energy, improve sexual function etc., by Lepidinm meyenii Walp, Radix Ginseng, Rhizoma Polygonati, Rhizoma Polygonati Odorati, Fructus Rubi, Poria, Fructus Gardeniae, green tea, light The medicinal and edible plant optimization such as Folium Bambusae, Radix Glycyrrhizae compounds.On the one hand, qi-restoratives primordial QI reinforcing, nourish body, empty must mend, canonical is prosperous, tired from Remove;On the other hand, adjust smooth will, comfortable smooth meaning, refreshing must pacify, the heart is then peaceful, and fatigue can disappear.
Preferably, described fatigue alleviating, the maca composition of raising energy, it is made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 40 ~ 50%, Radix Ginseng 2 ~ 5%, Rhizoma Polygonati 5 ~ 12%, Rhizoma Polygonati Odorati 3 ~ 8%, Fructus Rubi 5 ~ 10%, Poria 3 ~ 7%, Fructus Gardeniae 1 ~ 4%, green tea 1 ~ 5%, Herba Lophatheri 1 ~ 5%, Radix Glycyrrhizae 4 ~ 10%, surplus is adjuvant.
It is highly preferred that described fatigue alleviating, the maca composition of raising energy, by the raw material group of following percentage by weight Become: Lepidinm meyenii Walp 45%, Radix Ginseng 3%, Rhizoma Polygonati 10%, Rhizoma Polygonati Odorati 5%, Fructus Rubi 8%, Poria 5%, Fructus Gardeniae 2%, green tea 3%, Herba Lophatheri 3%, Radix Glycyrrhizae 6%, surplus is adjuvant.
Preferably, described raw material is through raw material screening, directly pulverizes the fine powder being less than 100 mesh for particle diameter.
The fatigue alleviating of the present invention, improving in the maca composition of energy, described adjuvant is solid preparation adjuvant;By described Maca composition makes the most acceptable dosage form.Described adjuvant can be conventional solid preparation adjuvant.
The fatigue alleviating of the present invention, the maca composition of raising energy, can use the preparation method that solid preparation is conventional, Described dosage form is pill, tablet, capsule, granule, slow releasing agent, controlled release agent, quick releasing formulation, Traditional Chinese medicine granule, soft extracts Agent, oral liquid or lyophilized injectable powder etc..
Instructions of taking: oral, daily intake < 5g, it is proposed that ante cibum 30 ~ 60, min hydromel took by day.
Suitable population: blood deficiency deficiency of YIN person, it is proposed that start low dose and take, gradually increment after 2 ~ 3 days.
It is not suitable for crowd: yang hyperactivity has people's inedibility of fire.
Part population has symptom of slightly getting angry, and can pass through the how edible green vegetable of dinner, drink water more and alleviate, such as disease Shape does not disappear and can decrement or interval take.
Compared with prior art, the beneficial effects of the present invention is: the maca composition that (1) present invention provides is to various Fatigue and sub-health population that reason causes have obvious resisting fatigue effect;
(2) present invention fatigue alleviating, improve energy compositions preparation technology simple and easy to do, production cost is low, it is simple to industry Metaplasia is produced;
(3) can make multiple dosage form as required, taking convenience, the property of medicine is gentle, and raw material is natural food materials, has no side effect.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, unless stated otherwise, in the present invention Technological means used is method known in those skilled in the art.It addition, embodiment is interpreted as illustrative, and Unrestricted the scope of the present invention, the spirit and scope of the invention are limited only by the claims that follow.For those skilled in the art For, on the premise of without departing substantially from spirit and scope of the present invention, the material component in these embodiments and consumption are carried out Various changes or change fall within protection scope of the present invention.
Maca composition in detailed description of the invention, through raw material screening, is pulverized as particle diameter less than the fine powder of 100 mesh, is then added Add routine solid preparation adjuvant, can be made into pill, tablet, capsule, granule, slow releasing agent, controlled release agent, quick releasing formulation, in Medicine composition granule, soft extract, oral liquid or lyophilized injectable powder etc..
Embodiment 1
The fatigue alleviating of the present invention, the maca composition of raising energy, be made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 45%, Radix Ginseng 3%, Rhizoma Polygonati 10%, Rhizoma Polygonati Odorati 5%, Fructus Rubi 8%, Poria 5%, Fructus Gardeniae 2%, green tea 3%, Herba Lophatheri 3%, Radix Glycyrrhizae 6%, surplus is auxiliary Material.
Described adjuvant is conventional tablet adjuvant, by above-mentioned formula, described maca composition is made tablet.
Embodiment 2
The fatigue alleviating of the present invention, the maca composition of raising energy, be made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 40%, Radix Ginseng 5%, Rhizoma Polygonati 12%, Rhizoma Polygonati Odorati 3%, Fructus Rubi 5%, Poria 7%, Fructus Gardeniae 4%, green tea 1%, Herba Lophatheri 5%, Radix Glycyrrhizae 4%, surplus is auxiliary Material.
Described adjuvant is conventional tablet adjuvant, by above-mentioned formula, described maca composition is made tablet.
Embodiment 3
The fatigue alleviating of the present embodiment, the maca composition of raising energy, be made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 50%, Radix Ginseng 2%, Rhizoma Polygonati 5%, Rhizoma Polygonati Odorati 8%, Fructus Rubi 10%, Poria 3%, Fructus Gardeniae 1%, green tea 5%, Herba Lophatheri 1%, Radix Glycyrrhizae 10%, surplus For adjuvant.
Described adjuvant is conventional tablet adjuvant, by above-mentioned formula, described maca composition is made tablet.
Embodiment 4
The fatigue alleviating of the present embodiment, the maca composition of raising energy, be made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 60%, Radix Ginseng 1%, Rhizoma Polygonati 3%, Rhizoma Polygonati Odorati 10%, Fructus Rubi 3%, Poria 2%, Fructus Gardeniae 0.5%, green tea 0.5%, Herba Lophatheri 0.5%, Radix Glycyrrhizae 1%, surplus is adjuvant.
Described adjuvant is conventional pill adjuvant, by above-mentioned formula, described maca composition is made pill.
Embodiment 5
The fatigue alleviating of the present embodiment, the maca composition of raising energy, be made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 30%, Radix Ginseng 6%, Rhizoma Polygonati 15%, Rhizoma Polygonati Odorati 1%, Fructus Rubi 12%, Poria 10%, Fructus Gardeniae 5%, green tea 6%, Herba Lophatheri 7%, Radix Glycyrrhizae 12%, remaining Amount is adjuvant.
Described adjuvant is conventional granulates agent adjuvant, by above-mentioned formula, described maca composition is made granule.
Comparative example 1
The fatigue alleviating of this comparative example, the maca composition of raising energy, be made up of the raw material of following percentage by weight: Lepidinm meyenii Walp 45%, Radix Ginseng 10%, Rhizoma Polygonati 2%, Rhizoma Polygonati Odorati 15%, Fructus Rubi 1%, Poria 1%, Fructus Gardeniae 4%, green tea 3%, Herba Lophatheri 3%, Radix Glycyrrhizae 6%, surplus For adjuvant.
Described adjuvant is conventional tablet adjuvant, by above-mentioned formula, described maca composition is made tablet.
Application examples 1
The maca composition of the embodiment of the present invention 1 ~ 5 and the fatigue alleviating of comparative example 1, raising energy is carried out resisting fatigue effect comment Valency is tested.
1), experimental raw: the composite formula of embodiment 1 ~ 5 is set to sample A, B, C, D, E group, by comparative example 1 Composite formula be set to positive controls, with oral distilled water blank group.
2), experimental subject: selecting Balb/c mice, 5 week old are male, body weight 20 ± 2 g, and mice adaptability was fed after 3 days, Adaptability is swum 10 min, eliminates the mice that can not swim, within the 4th day, carries out mice heavy burden (5% body weight) swimming test and exhaust to power, Record swimming time, Burden-Swimming Ability of KM and body weight according to mice are grouped.Mice is divided into 19 groups, often group 10, point It not blank group, sample A/B/C/D/E basic, normal, high dosage group, positive controls basic, normal, high dosage group.
3), dosage: the selection of test dose is arranged according to early stage preliminary result, and by Mice Body restatement, sample is low Dosage, middle dosage and high dose group are respectively 0.5 g/kg, 1 g/kg and 1.5 g/kg.
4), experimental technique:
Power exhausts experiment: dissolved by sample distilled water, makes the concentration of sample be respectively 5g/L, 10g/L and 15g/L, sample sets with Positive controls fills hello 0.1L/kg (body weight) every day;The distilled water of blank group gavage same volume, every morning 1 time, Continuous 30 days.Each group last fills after feeding 30min, and mice is placed to plastics pond (80 cm × 40, cm × 45 cm) middle reaches Swimming, depth of water is 35 cm, and water temperature be (25 ± 1) DEG C, and mouse tail is born the sheet lead of Mouse Weight 5% and carried out power and exhaust swimming reality Test that (power exhausts standard: heavy burden mice strokes is substantially lacked of proper care, it is impossible to adhering to or sink under water can not emersion water more than 10 s Face respiratory nasal is considered to reach power and exhausts state, is picked up rapidly), and record swimming time, the results are shown in Table 1.
Table 1 mice burden swimming time contrast (x ± sd, min)
Note: * P < 0.05, * * P < 0.01 and blank group ratio.
Analyze: as it can be seen from table 1 compared with blank group and positive controls, the fatigue alleviating of the present invention, raising The maca composition difference embodiment basic, normal, high dosage group of energy, all can be obviously prolonged the mice burden swimming time, and implement The effect of example 1 ~ 3 formula is better than embodiment 4 ~ 5;Wherein, dosage group low, middle has significant difference (P < 0.05), high agent Amount group has pole significant difference (P < 0.01), illustrates that the rational proportion of the present invention can be remarkably reinforced mice when physical load Ability to bear, there is significant resisting kinetic fatigue effect.
Application examples 2
Beneficial effects of the present invention is further illustrated below in conjunction with clinical data.
1), clinical data: outpatient service and inpatient 150 example, 25 ~ 60 years old age, 40 years old mean age.
2), diagnostic criteria: 1. pale complexion, dizziness, muscle twitches, dyspnea, dry mouth and parching tongue, hoarseness, tired Weak etc.;The most nose heave, tiredness with somnolence, limbs fatigue do not receives, and is disinclined to speech, dislikes food anorexia, and thin white fur of tongue is greasy, or thick greasy, or tongue Matter is the lightest;3. limbs are listless and aching, tinnitus, muddle-headed, the hypomnesis of spirit or have soreness of the waist and knees, and heel is ached;4. sleep not Foot, insomnia and dreamful sleep, fright at night, middle early awakening, cardiopalmus etc.;5. distraction, impatient irritability, short-tempered, there is no patience, emotion Low, bradykinesia, absent minded etc.;6. presenility, lusterless complexion, facial wrinkles or pigmented spots, limb occur too early Body pachylosis, dry and astringent, desquamation is more;Refer to that (toe) first loses normal smooth and gloss;Alopecia, fluffy dirt is easily broken, loss of gloss; 7. there is seminal emission, sexual impotence, premature ejaculation, hyposexuality in man;There is menoxenia or amenorrhea, hyposexuality etc. in advance in woman.
3), Therapeutic Method: of the present invention fatigue alleviating is administered orally, improves tablet prepared by energy maca composition embodiment 1, often Sheet 0.5g, one time 2, every day 2 ~ 3 times, 1 hour ante cibum took with hydromel, and took 2 months.
4), efficacy assessment standard: 1. clinical recovery: above-mentioned fatigue symptom complete incidence graph, even if having mild episode once in a while not Medication is needed to alleviate;The most effective: fatigue conditions the most substantially alleviates;3. take a turn for the better: fatigue conditions has alleviated;The most invalid: tired Labor situation does not has any improvement.
5), therapeutic outcome: after taking 2 months, fully recover number 67 people, rate 44.7% of recovering;Effective number 73 people, obvious effective rate 48.7%;Improvement number 6 people, improvement rate 4%;Invalid number 4 people, inefficiency 2.7%.The effective percentage for the treatment of reaches 97.3%, shows this The fatigue alleviating of invention maca composition, raising energy effect are notable.

Claims (4)

1. a fatigue alleviating, the maca composition of raising energy, it is characterised in that by the raw material group of following percentage by weight Become: Lepidinm meyenii Walp 30 ~ 60%, Radix Ginseng 1 ~ 6%, Rhizoma Polygonati 3 ~ 15%, Rhizoma Polygonati Odorati 1 ~ 10%, Fructus Rubi 3 ~ 12%, Poria 2 ~ 10%, Fructus Gardeniae 0.5 ~ 5%, Green tea 0.5 ~ 6%, Herba Lophatheri 0.5 ~ 7%, Radix Glycyrrhizae 1 ~ 12%, surplus is adjuvant.
Fatigue alleviating the most according to claim 1, the maca composition of raising energy, it is characterised in that by following weight Percentage ratio raw material composition: Lepidinm meyenii Walp 40 ~ 50%, Radix Ginseng 2 ~ 5%, Rhizoma Polygonati 5 ~ 12%, Rhizoma Polygonati Odorati 3 ~ 8%, Fructus Rubi 5 ~ 10%, Poria 3 ~ 7%, Fructus Gardeniae 1 ~ 4%, green tea 1 ~ 5%, Herba Lophatheri 1 ~ 5%, Radix Glycyrrhizae 4 ~ 10%, surplus is adjuvant.
Fatigue alleviating the most according to claim 1 and 2, the maca composition of raising energy, it is characterised in that described adjuvant For solid preparation adjuvant, described maca composition is made the most acceptable dosage form.
Fatigue alleviating the most according to claim 3, the maca composition of raising energy, it is characterised in that described dosage form is Pill, tablet, capsule, granule, slow releasing agent, controlled release agent, quick releasing formulation, Traditional Chinese medicine granule, soft extract, liquid oral Preparation or lyophilized injectable powder.
CN201610621307.2A 2016-08-02 2016-08-02 A kind of fatigue alleviating, the maca composition of raising energy Pending CN106075152A (en)

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CN107233491A (en) * 2017-06-12 2017-10-10 拉萨净土睿健生物产业发展有限公司 It is a kind of to improve the antifatigue maca composition of energy
CN107233490A (en) * 2017-06-12 2017-10-10 拉萨净土睿健生物产业发展有限公司 A kind of maca composition of supplementing qi and nourishing yin beautifying face and moistering lotion
CN107467661A (en) * 2017-08-17 2017-12-15 武汉华士特工业生物技术开发有限公司 A kind of maca composition for treating fatigue type sub-health and preparation method thereof
CN114041595A (en) * 2021-12-30 2022-02-15 法尔玛国际健康管理有限公司 Nutritional composition for conditioning female menstrual period syndrome and promoting reproductive health

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CN104435536A (en) * 2014-11-11 2015-03-25 武汉名实生物医药科技有限责任公司 Preparation method of compound preparation capable of delaying aging, improving sexual functions and resisting fatigue
CN105296300A (en) * 2015-11-11 2016-02-03 王宝珍 Maca and ginseng liquor and production process thereof

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CN104042662A (en) * 2014-06-20 2014-09-17 苏州法莫生物技术有限公司 Compound maca powder preparation
CN104435536A (en) * 2014-11-11 2015-03-25 武汉名实生物医药科技有限责任公司 Preparation method of compound preparation capable of delaying aging, improving sexual functions and resisting fatigue
CN105296300A (en) * 2015-11-11 2016-02-03 王宝珍 Maca and ginseng liquor and production process thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107233491A (en) * 2017-06-12 2017-10-10 拉萨净土睿健生物产业发展有限公司 It is a kind of to improve the antifatigue maca composition of energy
CN107233490A (en) * 2017-06-12 2017-10-10 拉萨净土睿健生物产业发展有限公司 A kind of maca composition of supplementing qi and nourishing yin beautifying face and moistering lotion
CN107467661A (en) * 2017-08-17 2017-12-15 武汉华士特工业生物技术开发有限公司 A kind of maca composition for treating fatigue type sub-health and preparation method thereof
CN114041595A (en) * 2021-12-30 2022-02-15 法尔玛国际健康管理有限公司 Nutritional composition for conditioning female menstrual period syndrome and promoting reproductive health

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Application publication date: 20161109