CN106068455B - 使用Luterial的形态特征用于诊断疾病的方法 - Google Patents

使用Luterial的形态特征用于诊断疾病的方法 Download PDF

Info

Publication number
CN106068455B
CN106068455B CN201480050194.4A CN201480050194A CN106068455B CN 106068455 B CN106068455 B CN 106068455B CN 201480050194 A CN201480050194 A CN 201480050194A CN 106068455 B CN106068455 B CN 106068455B
Authority
CN
China
Prior art keywords
luterial
cancer
shape
patient
observed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480050194.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN106068455A (zh
Inventor
权宁娥
崔元哲
崔硕训
崔彰训
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luterion Co ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN106068455A publication Critical patent/CN106068455A/zh
Application granted granted Critical
Publication of CN106068455B publication Critical patent/CN106068455B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/4833Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7023(Hyper)proliferation
    • G01N2800/7028Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nanotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Ecology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
CN201480050194.4A 2013-07-12 2014-01-14 使用Luterial的形态特征用于诊断疾病的方法 Active CN106068455B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2013-0082060 2013-07-12
KR20130082060 2013-07-12
PCT/KR2014/000393 WO2015005553A1 (ko) 2013-07-12 2014-01-14 루테리알의 형태특성을 이용한 질병의 진단방법

Publications (2)

Publication Number Publication Date
CN106068455A CN106068455A (zh) 2016-11-02
CN106068455B true CN106068455B (zh) 2018-05-11

Family

ID=52280202

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480050194.4A Active CN106068455B (zh) 2013-07-12 2014-01-14 使用Luterial的形态特征用于诊断疾病的方法

Country Status (6)

Country Link
US (1) US10338061B2 (https=)
EP (1) EP3021119A4 (https=)
JP (1) JP2016526688A (https=)
KR (8) KR20150007922A (https=)
CN (1) CN106068455B (https=)
WO (1) WO2015005553A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014299561B2 (en) 2013-06-24 2017-06-08 Ablbio Antibody-drug conjugate having improved stability and use thereof
US10590384B2 (en) 2014-01-14 2020-03-17 Luterion Co., Ltd. Luterial and method for isolating and culturing the same
HK1231558A1 (zh) * 2014-01-14 2017-12-22 崔元哲 使用luterial的形态学特徵筛选癌症预防剂或抗癌剂的方法
HK1231516A1 (zh) * 2014-01-14 2017-12-22 崔元哲 Luterial和用於其分离及培养的方法
KR101766373B1 (ko) * 2015-01-05 2017-08-09 권영아 루테리온을 이용한 암세포의 텔로머라아제 억제방법
EP3243902A4 (en) * 2015-01-06 2018-05-30 Luterion Co., Ltd. Luterion and separating and culturing methods for same
US20230090858A1 (en) * 2021-09-23 2023-03-23 The Trustees Of The University Of Pennsylvania Analysis of pleural lines for the diagnosis of lung conditions
US12196755B2 (en) 2021-12-02 2025-01-14 Zymeron Corporation Immunoassay platform for the serological discrimination of closely related viruses

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022432A1 (en) * 1998-10-08 2000-04-20 Silvia Maria Doglia A method for the detection of mitochondrial alterations
WO2006054296A2 (en) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methods of detecting prostate cancer
US20090311664A1 (en) * 2005-12-22 2009-12-17 Yuman Fong Method for Detection of Cancer Cells Using Virus
CN102084000A (zh) * 2008-02-01 2011-06-01 总医院有限公司 微泡在医学疾病和病况的诊断、预后以及治疗中的用途
WO2012135844A3 (en) * 2011-04-01 2012-11-22 Cornell University Circulating exosomes as diagnostic/prognostic indicators and therapeutic targets of melanoma and other cancers

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1473945A (en) * 1973-05-24 1977-05-18 Gen Electric Method for preparing slides for blood evaluation
US4581223A (en) * 1980-03-12 1986-04-08 Lawrence Kass Individual leukocyte determination by means of differential metachromatic dye sorption
JPS6064909A (ja) 1983-09-20 1985-04-13 Shiseido Co Ltd 化粧料
JPH0412243A (ja) * 1990-05-02 1992-01-16 Asahi Chem Ind Co Ltd 直孔性フィルター及びその製造方法
JP2002223768A (ja) * 2001-01-31 2002-08-13 Japan Science & Technology Corp ヒトミトコンドリア蛋白質とこの蛋白質をコードするポリヌクレオチド
KR20030033134A (ko) * 2001-10-17 2003-05-01 장준근 적혈구의 물리적 특성을 이용한 질환 진단 장치 및 그진단 방법
US20040009518A1 (en) * 2002-05-14 2004-01-15 The Chinese University Of Hong Kong Methods for evaluating a disease condition by nucleic acid detection and fractionation
US9176121B2 (en) * 2004-02-13 2015-11-03 Roche Diagnostics Hematology, Inc. Identification of blood elements using inverted microscopy
JP5704590B2 (ja) 2010-02-05 2015-04-22 国立大学法人東京農工大学 サイズ選択マイクロキャビティアレイを用いた循環腫瘍細胞の検出
JP5673025B2 (ja) * 2010-11-26 2015-02-18 ユーハ味覚糖株式会社 新規レスベラトロール誘導体
HK1231516A1 (zh) 2014-01-14 2017-12-22 崔元哲 Luterial和用於其分离及培养的方法
HK1231558A1 (zh) 2014-01-14 2017-12-22 崔元哲 使用luterial的形态学特徵筛选癌症预防剂或抗癌剂的方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022432A1 (en) * 1998-10-08 2000-04-20 Silvia Maria Doglia A method for the detection of mitochondrial alterations
WO2006054296A2 (en) * 2004-11-17 2006-05-26 Spectrum Dynamics Llc Methods of detecting prostate cancer
US20090311664A1 (en) * 2005-12-22 2009-12-17 Yuman Fong Method for Detection of Cancer Cells Using Virus
CN102084000A (zh) * 2008-02-01 2011-06-01 总医院有限公司 微泡在医学疾病和病况的诊断、预后以及治疗中的用途
WO2012135844A3 (en) * 2011-04-01 2012-11-22 Cornell University Circulating exosomes as diagnostic/prognostic indicators and therapeutic targets of melanoma and other cancers

Also Published As

Publication number Publication date
US20160169870A1 (en) 2016-06-16
WO2015005553A1 (ko) 2015-01-15
CN106068455A (zh) 2016-11-02
KR20230009999A (ko) 2023-01-17
EP3021119A4 (en) 2017-04-19
US10338061B2 (en) 2019-07-02
KR20200139117A (ko) 2020-12-11
KR20250102000A (ko) 2025-07-04
JP2016526688A (ja) 2016-09-05
KR20160115886A (ko) 2016-10-06
KR20220050844A (ko) 2022-04-25
KR20240001089A (ko) 2024-01-03
KR20150007922A (ko) 2015-01-21
KR20200007065A (ko) 2020-01-21
EP3021119A1 (en) 2016-05-18

Similar Documents

Publication Publication Date Title
CN106068455B (zh) 使用Luterial的形态特征用于诊断疾病的方法
JP2023055865A (ja) ルテリアル、並びにその分離および培養方法
US20180059114A1 (en) Magnetic nanostructure for detecting and isolating circulating tumor cells comprising antibody- and magnetic nanoparticle-conjugated conductive polymer
WO2017174609A1 (en) Diagnostic methods for patient specific therapeutic decision making in cancer care
AU2008249153A1 (en) Methods and reagents for the rapid and efficient isolation of circulating cancer cells
Haghighi et al. Aptamer/magnetic nanoparticles decorated with fluorescent gold nanoclusters for selective detection and collection of human promyelocytic leukemia (HL-60) cells from a mixture
HK1213639A1 (zh) 细胞图像的归类方法
CN104711263A (zh) 一种用于靶向人鼻咽癌细胞的核酸适配体序列及应用
CN112014563A (zh) 直接检测血液中循环肿瘤细胞的分子信标传递体系、其制备方法及应用
CN114487391B (zh) 仿生免疫磁纳米颗粒、其制备方法及应用
CN118050512A (zh) 检测来自尿液囊泡的蛋白标志物的试剂在制备乳腺癌诊断试剂盒中的应用
Chen et al. Capture and identification of heterogeneous circulating tumor cells using transparent nanomaterials and quantum dots-based multiplexed imaging
CN109100504B (zh) 一种血小板-白细胞混合膜包被免疫磁珠及其制备方法与应用
US10590384B2 (en) Luterial and method for isolating and culturing the same
Ke et al. Capture and lyase-triggered release of circulating tumor cells using a disposable microfluidic chip embedded with core/shell nylon-6/Ca (ii)-alginate immunofiber mats
JP4852703B2 (ja) 脳腫瘍の検出方法及びそれに用いる脳腫瘍の検出物質
KR101150840B1 (ko) 검체 시료의 응집용 조성물, 이를 이용한 파라핀 블록의 제작방법 및 상기 파라핀 블록을 이용한 검체 시료의 현미경 관찰방법
CN117004567A (zh) 伪中性粒细胞、其在制备抑制循环肿瘤细胞转移的药物或试剂中的应用
WO2020233572A1 (zh) 多肽磁性纳米颗粒、其制备方法及应用
Azharuddin et al. Synthesis Of Nanoparticles As A Probe For Diagnosis Of Dry Eye Disease

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CB03 Change of inventor or designer information

Inventor after: Quan Ninge

Inventor after: Cui Yuanzhe

Inventor after: Cui Shuoxun

Inventor after: Cui Zhangxun

Inventor before: Quan Ninge

Inventor before: Cui Yuanzhe

Inventor before: Cui Shuoxun

Inventor before: Cui Zhangxun

Inventor before: Quan Shengbi

Inventor before: Quan Xianting

COR Change of bibliographic data
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20240130

Address after: Seoul, South Kerean

Patentee after: LUTERION Co.,Ltd.

Country or region after: Republic of Korea

Address before: Seoul special city

Patentee before: Quan Ninge

Country or region before: Republic of Korea

Patentee before: Cui Yuanzhe

Country or region before: Han Guo

Patentee before: Cui Shuoxun

Patentee before: Cui Zhangxun

TR01 Transfer of patent right