CN106038889A - Preparation method of traditional Chinese medicine mixture capable of clearing lung to relieve cough - Google Patents
Preparation method of traditional Chinese medicine mixture capable of clearing lung to relieve cough Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a preparation method of a traditional Chinese medicine mixture capable of clearing the lung to relieve a cough. The mixture is prepared from bitter apricot kernels, fried radix scutellariae, unprocessed rhizoma pinelliae, radix peucedani, fructus perillae and 75 g of herba schizonepetae. The preparation method comprises the steps that apricot kernels, radix peucedani and herba schizonepetae are distilled by steam, and about 250 ml of distillate is taken for standby application; medicine residues, medicine liquid obtained after distillation and the other two herbs including radix scutellariae and the like are decocted twice by adding water and decocted for 1 h every time, decoction solutions are mixed, standing is conducted for 24 h, supernatant liquid is taken, concentrated to be liquid with the relative density of 1.07-1.09 (at the temperature of 80 DEG C-850 DEG C) and then cooled, ethyl alcohol is added, the liquid is stirred to be uniform, standing is conducted, alcohol-precipitated supernatant liquid is taken, ethyl alcohol in the supernatant liquid is recycled, the distillate, 150 g of sucrose and 3 g of sodium benzoate are added, and the liquid is prepared to be 1,000 ml by adding water; the liquid is mixed to be uniform, filtered, subpackaged and sterilized, and then the traditional Chinese medicine mixture is obtained. The traditional Chinese medicine mixture has the characters that the mixture is brownish yellow to light brown liquid; the smell is fragrant, and the taste is sweet and slightly pungent; the relative density is no lower than 1.06, and the pH value should be 4.0-6.0.
Description
Technical field
The present invention relates to the preparation method of the herb mixture of a kind of clearing away lung-heat to relieve cough, belong to the field of Chinese medicines.
Background technology
Nourishing the lung to arrest cough refers to use nourishing YIN and moistening the lung treatment by Chinese herbs cough due to yin deficiency, is also a kind of therapeutic effect of the traditional Chinese medical science.Cough
It it is the modal a kind of symptom of respiratory tract disease.Cough is human body one protectiveness defense function.By cough, can discharge and exhale
Inhale the secretions in road or invade endotracheal foreign body.Only have cough and without expectorant be referred to as dry cough, it is seen that in multiple disease.
The cause of disease of cough has:
1. chronic pharyngitis: patient is pharyngeal to be dried, and has scratchiness and a sense of discomfort, and thus stimulate to send and a burst of cough sound, oneself
Can find to swallow rear wall mucomembranous surface facing to mirror lips coarse, have the thin vessels of many expansions, have transparent little time serious
BAIPAO, is common with pure.
2. chronic laryngitis: if patient's dry cough, with hoarseness, feel that throat is dried and itch, pain smartly, just
It is likely to be laryngitis.
3. chronic bronchitis: person above middle age often coughs, brings up viscous sputum more or less, adds after waking up in the morning
Play, annual winter-spring season shows effect, alleviates summer or alleviate, and longer Finding case thorax of serious or time is broadening, should suspect
For chronic bronchitis.
4. bronchial asthma: if cough recurrent exerbation, such as dragsaw between larynx when breathing, patient feels uncomfortable in chest, exhales simultaneously
Cough can be induced when inhaling cold season difficult, every or contact certain allergin, should check whether suffer from bronchial asthma.
5. pulmonary tuberculosis, pulmonary carcinoma: it is micro-that patient coughs low voice, cough with blood-flecked phlegm or spitting of blood, feel weak all over, appetite reduces, health
Day by day becoming thin, afternoon and night body temperature increases, and perspires in bed and increases, time have nervous, while the most rubescent with two cheekbones.
6. infectious cough: respiratory tract disease such as upper respiratory tract infection or antibacterial infect also can cause cough.
7. other reason cough: the diseases such as foreign body in trachea, pleuritis, hydrothorax and many physics, chemical factor are also
Cough can be caused.
It is desirable to provide the preparation method of the herb mixture of a kind of clearing away lung-heat to relieve cough, it has a good lung heat clearing, cough-relieving,
Reduce phlegm effect, be highly suitable for exogenous cough, additionally, it is observed that have the curative effect of good alleviation xerophthalmia.
Summary of the invention
The technical problem existed based on background technology, the present invention provides the preparation side of the herb mixture of a kind of clearing away lung-heat to relieve cough
Method, it has good lung heat clearing, cough-relieving, effect of reducing phlegm, and is highly suitable for exogenous cough, additionally, it is observed that have good slow
Solve the curative effect of xerophthalmia.
Technical scheme is as follows:
A kind of preparation method of the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 50-52 part
Radix Scutellariae (stir-fry) 50 parts
The Rhizoma Pinelliae (giving birth to) 110-115 part
Radix Peucedani 110-116 part
Fructus Perillae 112 parts
Herba Schizonepetae 75-80 part
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;After medicinal residues, distillation
The two taste boiling secondaries such as medicinal liquid and remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relatively
Density is 1.07~1.09 (80~85 DEG C), cooling, adds equivalent ethanol, stirs, stands, and takes precipitate with ethanol supernatant, and supernatant reclaims
Ethanol, adds above-mentioned distillate, sucrose 150g, sodium benzoate 3g, and add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, i.e.
?.
The invention have benefit that:
The herb mixture of the present invention has good lung heat clearing, cough-relieving, effect of reducing phlegm, and is highly suitable for exogenous cough, this
The outer curative effect also finding there is good alleviation xerophthalmia.
Detailed description of the invention
Embodiment 1:
A kind of preparation method of the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 50g
Radix Scutellariae (stir-fry) 50g
The Rhizoma Pinelliae (giving birth to) 115g
Radix Peucedani 110g
Fructus Perillae 112g
Herba Schizonepetae 80g
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;After medicinal residues, distillation
The two taste boiling secondaries such as medicinal liquid and remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relatively
Density is 1.07~1.09 (80~85 DEG C), cooling, adds equivalent ethanol, stirs, stands, and takes precipitate with ethanol supernatant, and supernatant reclaims
Ethanol, adds above-mentioned distillate, sucrose 150g, sodium benzoate 3g, and add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, i.e.
?.
Embodiment 2:
A kind of preparation method of the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 52g
Radix Scutellariae (stir-fry) 50g
The Rhizoma Pinelliae (raw 110g
Radix Peucedani 116g
Fructus Perillae 112g
Herba Schizonepetae 75g
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;After medicinal residues, distillation
The two taste boiling secondaries such as medicinal liquid and remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relatively
Density is 1.07~1.09 (80~85 DEG C), cooling, adds equivalent ethanol, stirs, stands, and takes precipitate with ethanol supernatant, and supernatant reclaims
Ethanol, adds above-mentioned distillate, sucrose 150g, sodium benzoate 3g, and add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, i.e.
?.
Embodiment 3:
A kind of preparation method of the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 51g
Radix Scutellariae (stir-fry) 50g
The Rhizoma Pinelliae (giving birth to) 114g
Radix Peucedani 111g
Fructus Perillae 112g
Herba Schizonepetae 79g
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;After medicinal residues, distillation
The two taste boiling secondaries such as medicinal liquid and remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relatively
Density is 1.07~1.09 (80~85 DEG C), cooling, adds equivalent ethanol, stirs, stands, and takes precipitate with ethanol supernatant, and supernatant reclaims
Ethanol, adds above-mentioned distillate, sucrose 150g, sodium benzoate 3g, and add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, i.e.
?.
Embodiment 4:
A kind of preparation method of the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 50g
Radix Scutellariae (stir-fry) 50g
The Rhizoma Pinelliae (giving birth to) 111g
Radix Peucedani 115g
Fructus Perillae 112g
Herba Schizonepetae 76g
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;After medicinal residues, distillation
The two taste boiling secondaries such as medicinal liquid and remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relatively
Density is 1.07~1.09 (80~85 DEG C), cooling, adds equivalent ethanol, stirs, stands, and takes precipitate with ethanol supernatant, and supernatant reclaims
Ethanol, adds above-mentioned distillate, sucrose 150g, sodium benzoate 3g, and add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, i.e.
?.
Embodiment 5:
A kind of preparation method of the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 52g
Radix Scutellariae (stir-fry) 50g
The Rhizoma Pinelliae (giving birth to) 113g
Radix Peucedani 112g
Fructus Perillae 112g
Herba Schizonepetae 78g
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;After medicinal residues, distillation
The two taste boiling secondaries such as medicinal liquid and remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relatively
Density is 1.07~1.09 (80~85 DEG C), cooling, adds equivalent ethanol, stirs, stands, and takes precipitate with ethanol supernatant, and supernatant reclaims
Ethanol, adds above-mentioned distillate, sucrose 150g, sodium benzoate 3g, and add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, i.e.
?.
Embodiment 6:
(1) exogenous cough's curative effect:
Choose 50 ages 20-50 year between, man patient 30, female patient 20, there is typical exogenous cough's disease
The patient of shape, every day 2 times, each 5ml, follow up a case by regular visits to record after 3 days, feedback is cured or effective volunteer.
Drink the herb mixture of the present invention to described volunteer, drink the herb mixture of the present invention to described volunteer
With, every day 2 times, each 5ml, follow up a case by regular visits to record after 3 days, feedback is cured or effective volunteer.
Result: feedback healing number 48 people, alleviates 2 people, and effective percentage is up to 100%.
(2) treatment xerophthalmia curative effect:
Choose 100 ages between 20-50 year, the patient suffering from xerophthalmia because seeing computer, mobile phone, TV for a long time,
The ill time limit, all between 2-4, is equally divided into 5 groups, often organizes 20 people, without significant difference statistically between each group.
Drink the herb mixture of the present invention to described volunteer, every day 2 times, each 5ml, follows up a case by regular visits to record after 1 month, instead
Feedback is cured or effective volunteer.
Result is as shown in the table.
Total efficiently individual quantity | Cure number completely | Alleviation number | |
Embodiment 1 | 18 | 17 | 1 |
Embodiment 2 | 20 | 16 | 4 |
Embodiment 3 | 19 | 18 | 1 |
Embodiment 4 | 20 | 18 | 2 |
Embodiment 5 | 20 | 20 | 0 |
As can be seen here, the herb mixture of the present invention is for suffering from the complete of xerophthalmia because seeing computer, mobile phone, TV for a long time
Cure rate is high, disables rear relapse rate low.
In sum, the herb mixture of the present invention has good lung heat clearing, cough-relieving, and effect of reducing phlegm, outside being highly suitable for
Sense cough, additionally, it is observed that have the curative effect of good alleviation xerophthalmia.
The above, the only present invention preferably detailed description of the invention, but protection scope of the present invention is not limited thereto,
Any those familiar with the art in the technical scope that the invention discloses, according to technical scheme and
Inventive concept equivalent or change in addition, all should contain within protection scope of the present invention.
Claims (3)
1. a preparation method for the herb mixture of clearing away lung-heat to relieve cough, its step is as follows:
(1) preparation of raw material:
Following raw material is taken according to parts by weight,
Semen Armeniacae Amarum 50-52 part
Radix Scutellariae (stir-fry) 50 parts
The Rhizoma Pinelliae (giving birth to) 110-115 part
Radix Peucedani 110-116 part
Fructus Perillae 112 parts
Herba Schizonepetae 75-80 part;
(2) prepare:
Above Six-element, Semen Armeniacae Amarum, Radix Peucedani, Herba Schizonepetae vapor distillation, take distillate about 250ml, standby;Medicinal liquid after medicinal residues, distillation
With the two taste boiling secondaries such as remaining Radix Scutellariae, each 1h, collecting decoction, stand 24h, take supernatant, be concentrated into relative density
It is 1.07~1.09 (80~850C), cooling, add equivalent ethanol, stir, stand, take precipitate with ethanol supernatant, supernatant reclaims ethanol,
Adding above-mentioned distillate, sucrose 150g, sodium benzoate 3g, add water modulation 1000ml, filters;Mixing, subpackage, sterilizing, to obtain final product.
2. the herb mixture of a clearing away lung-heat to relieve cough, it is characterised in that be made up of following raw material:
According to parts by weight,
Semen Armeniacae Amarum 50-52 part
Radix Scutellariae (stir-fry) 50 parts
The Rhizoma Pinelliae (giving birth to) 110-115 part
Radix Peucedani 110-116 part
Fructus Perillae 112 parts
Herba Schizonepetae 75-80 part.
3. the herb mixture that the method described in claim 1 prepares.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109224016A (en) * | 2018-11-27 | 2019-01-18 | 何雁玲 | A kind of relieving cough and reducing sputum cream of external application and preparation method thereof |
-
2016
- 2016-07-06 CN CN201610539512.4A patent/CN106038889A/en active Pending
Non-Patent Citations (3)
Title |
---|
孙德海: "《易混淆中药鉴别》", 31 July 2015, 中国医药科技出版社 * |
蔡向红等: "《新编百草名方大全》", 31 January 2015, 陕西科学技术出版社 * |
马卫平: "止嗽散加减治疗咳嗽31例临床观察", 《甘肃中医学院学报》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109224016A (en) * | 2018-11-27 | 2019-01-18 | 何雁玲 | A kind of relieving cough and reducing sputum cream of external application and preparation method thereof |
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Application publication date: 20161026 |