CN106037988B - A kind of multifunctional liquid-spraying administration combination unit local for experimental animal - Google Patents
A kind of multifunctional liquid-spraying administration combination unit local for experimental animal Download PDFInfo
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- CN106037988B CN106037988B CN201610522058.1A CN201610522058A CN106037988B CN 106037988 B CN106037988 B CN 106037988B CN 201610522058 A CN201610522058 A CN 201610522058A CN 106037988 B CN106037988 B CN 106037988B
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- plastics
- plastic
- mouse
- liquid
- metal
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- 238000010171 animal model Methods 0.000 title claims abstract description 13
- 238000005507 spraying Methods 0.000 title claims abstract description 12
- 229920003023 plastic Polymers 0.000 claims abstract description 114
- 239000004033 plastic Substances 0.000 claims abstract description 105
- 239000002184 metal Substances 0.000 claims abstract description 33
- 229910052751 metal Inorganic materials 0.000 claims abstract description 33
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000007789 sealing Methods 0.000 claims abstract description 8
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 3
- 239000010931 gold Substances 0.000 claims description 3
- 229910052737 gold Inorganic materials 0.000 claims description 3
- 240000001307 Myosotis scorpioides Species 0.000 abstract description 6
- 238000002474 experimental method Methods 0.000 abstract description 6
- 238000005516 engineering process Methods 0.000 abstract description 3
- 239000011248 coating agent Substances 0.000 abstract description 2
- 238000000576 coating method Methods 0.000 abstract description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 19
- 229920000742 Cotton Polymers 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 206010014025 Ear swelling Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 208000005298 acute pain Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Husbandry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Catching Or Destruction (AREA)
Abstract
The invention belongs to scientific experiment equipment technology field,Combination unit is administered more particularly to a kind of multifunctional liquid-spraying local for experimental animal,Including liquid-transfering device and mouse fixing,It is characterized in that,Micro quantitative determination liquid relief plastic tube head is provided with metal nuts interface in liquid-transfering device,The diplopore plastic hose that holds such as independent is connected by metal sealing two-way valve with metal nuts interface,The plastics hydrojet headrest is placed in double leaf ear plastics jet head,Double leaf ear plastics jet head is connected with appearance diplopore plastic hoses such as independences,Double leaf ear plastics jet head and independence etc. hold diplopore plastic hose and meet mouse ear shape and can realize that hydrojet is uniform,Mouse fixing assembling is simple,The head of mouse can be fixed very well,More mouse can be fixed simultaneously,Transparent outer cover can allow operator to understand mouse dynamic in time,Metal variable shape buckle is easily operated and played the role of fixed.The present invention can effectively solve the problems, such as the experimental data inaccuracy caused by uneven to mouse coating.
Description
Technical field
The invention belongs to scientific experiment equipment technology field, and in particular to a kind of multifunctional spraying local for experimental animal
Liquid administration combination unit.
Background technology
In basic pharmacology experiment, classical pharmacological experiment-mice ear experiment is commonly used, is frequently present of false positive
Or false negative result.
During ear swelling experiment is done, when experimenter causes scorching with dimethylbenzene to mouse ear, generally use is done
Method is to dip dimethylbenzene liquid applicator in the ear both sides of mouse with medical cotton stick or self-control cotton swab.Although so operation is convenient,
But obtained experimental data is extremely inaccurate.Problem is mainly manifested in the following aspects：First, the cause inflammation effect of dimethylbenzene is strong and weak
With dose relationship be present with dimethylbenzene amount, the dimethylbenzene dipped with cotton swab goes to smearing mouse ear both sides to cannot be guaranteed to smear every time
Amount it is the same；2nd, the process smeared every time is to hold cotton swab with hand to complete to smear, and caused by dimethylbenzene xylene inflammation can produce Acute Pain,
Mouse is in irritated, acutely hidden state, can so cause smearing position not fixed, dimethylbenzene applying amount is uneven；3rd, when
After having smeared dimethylbenzene, due to pain caused by inflammation can make mouse run helter-skelter disorderly lick disorderly rub, cause dimethylbenzene drug effect not have also
Play just disappearance etc..These problems can make that mouse ear swelling degree size is uneven, and each ear mass difference is larger, after being
Continuous data processing, in next step experiment direction produce wrong direction etc., and time-consuming, consumption people, effort, waste of resource.
The content of the invention
The purpose of the present invention is exactly to overcome above-mentioned deficiency, there is provided it is a kind of it is simple in construction, micro quantitative determination is accurate, easy to operate
Combination unit is administered for the local multifunctional liquid-spraying of experimental animal.
The technical solution adopted for the present invention to solve the technical problems is：A kind of multifunctional spraying local for experimental animal
Liquid administration combination unit, including liquid-transfering device and mouse fixing, liquid-transfering device includes micro quantitative determination liquid relief plastic tube 1, micro-
The appearance diplopore such as quantitatively pipette plastics catch bar 2, metal sealing two-way valve 3, metal nuts interface 4, independence plastic hose 5 is measured,
Double leaf ear plastics jet head 6 and the plastics hydrojet headrest 7, micro quantitative determination pipette plastics catch bar 2 can be in micro quantitative determination liquid relief
Moved in plastic tube 1, the head of micro quantitative determination liquid relief plastic tube 1 is provided with metal nuts interface 4, independence etc. and holds diplopore plastic hose 5
It is connected by metal sealing two-way valve 3 with metal nuts interface 4, the plastics hydrojet headrest 7 is placed in double leaf ear plastics jet head 6
Interior, double leaf ear plastics jet head 6 is connected with appearance diplopore plastic hoses 5 such as independences；Often set in mouse fixing fixes dress
Put including plastic bottom board 8, independent transparent oval plastic tube 9, plastics door closure 10, plastics catch bar 11, plastic septum 12 is transparent
Plastic dam 13 and metal variable shape buckle 14, independent transparent oval plastic tube 9 are fixed on plastic bottom board 8, and it is close to tail
Opening is provided with portion, plastics door closure 10 is placed on this opening, and transparent plastic baffle plate 13 is located at independent transparent oval plastic tube 9
Portion, plastics catch bar 11 are inserted and can moved back and forth in it, metal variable shape card from the independent transparent oval afterbody of plastic tube 9
Button 14 is fixed on transparent plastic baffle plate 13, is separated respectively with plastic septum 12 per sleeve fixture mechanism.
The invention has the advantages that the present invention can solve because to mouse coating it is uneven caused by experimental data not
The problem of accurate, two independently separated liquid-transfering device and mouse fixing be simple in construction, micro quantitative determination precisely, operation side
Just, more animal synchronization fixations and hydrojet administration can be met.Liquid-transfering device seal is good, can allow medicine quantitative accurate and
It can be used for multiple times, the appearance diplopore plastic hose such as double leaf ear plastics jet head and independence meets mouse ear shape and can be real
Existing hydrojet is uniform；Mouse fixing assembling is simple, can fix the head of mouse very well, transparent outer cover can allow operator and
When understand mouse dynamic, metal variable shape buckle easily operates and plays the role of fixed.
The invention will be further described with reference to the accompanying drawings and examples.
Brief description of the drawings
Fig. 1 is a kind of knot of the liquid-transfering device of the multifunctional liquid-spraying administration combination unit local for experimental animal of the present invention
Structure schematic diagram；
Fig. 2 is a kind of mouse fixing of the multifunctional liquid-spraying administration combination unit local for experimental animal of the present invention
Structural representation；
Fig. 3 is a kind of double leaf ear plastics of the multifunctional liquid-spraying administration combination unit local for experimental animal of the present invention
The structural representation of jet head 6；
Fig. 4 is a kind of mouse fixing of the multifunctional liquid-spraying administration combination unit local for experimental animal of the present invention
In amplify at 13,14 after structural representation.
In figure：
1st, micro quantitative determination liquid relief plastic tube, 2, micro quantitative determination pipette plastics catch bar, 3, metal sealing two-way valve, 4, gold
Belong to nut interface, 5, it is independent etc. hold diplopore plastic hose, 6, double leaf ear plastics jet head, 7, the plastics hydrojet headrest, 8, plastics
Bottom plate, 9, independent transparent oval plastic tube, 10, plastics door closure, 11, plastics catch bar, 12, plastic septum, 13, transparent plastic
Baffle plate, 14, metal variable shape buckle.
Embodiment
It is proposed by the present invention referring to Fig. 1-Fig. 4：A kind of multifunctional liquid-spraying administration group local for experimental animal attaches together
Put, including liquid-transfering device and mouse fixing, liquid-transfering device include micro quantitative determination liquid relief plastic tube 1, micro quantitative determination pipette
Plastics catch bar 2, metal sealing two-way valve 3, metal nuts interface 4, independence etc. hold diplopore plastic hose 5, double leaf ear plastics
Jet head 6 and the plastics hydrojet headrest 7, micro quantitative determination pipette plastics catch bar 2 can move in micro quantitative determination liquid relief plastic tube 1
Dynamic, the head of micro quantitative determination liquid relief plastic tube 1 is provided with the appearance diplopore such as metal nuts interface 4, independence plastic hose 5 and passes through metal sealing
Two-way valve 3 is connected with metal nuts interface 4, and the plastics hydrojet headrest 7 is placed in double leaf ear plastics jet head 6, the modeling of double leaf ear
Material jet head 6 is connected with appearance diplopore plastic hoses 5 such as independences；Every sleeve fixture mechanism in mouse fixing includes plastic bottom board
8, independent transparent oval plastic tube 9, plastics door closure 10, plastics catch bar 11, plastic septum 12, transparent plastic baffle plate 13 and gold
Belong to deformable buckle 14, independent transparent oval plastic tube 9 is fixed on plastic bottom board 8, and it is provided with opening at afterbody, modeling
Bin gate lid 10 is placed on this opening, and transparent plastic baffle plate 13 is located at the independent transparent oval head of plastic tube 9, plastics catch bar 11
Insert and can move back and forth in it from the independent transparent oval afterbody of plastic tube 9, metal variable shape buckle 14 is fixed on transparent
In plastic dam 13, separated respectively with plastic septum 12 per sleeve fixture mechanism.
In the present embodiment, mouse fixing is as shown in Fig. 2 be designed to that ten sets of independent fixing devices are fixed on modeling side by side
Expect on bottom plate 8, ten mouse can be fixed simultaneously, and spray to them.
Preparation：First each device is assembled as shown in accompanying drawing, then checks the air-tightness of liquid-transfering device part, with
And the stability of mouse fixing.
The course of work：
Step 1, product are got it filled in micro quantitative determination liquid relief plastic tube 1, press lightly on micro quantitative determination pipette plastics catch bar
2, untill treating that the both sides of double leaf ear plastics jet head 6 produce hydrojet in the plastics hydrojet headrest 7；
Step 2, metal variable shape buckle 14 is closed, open plastics door closure 10, by mouse head towards metal variable shape card
Button 14 is put into independent transparent oval plastic tube 9, is then shut off plastics door closure 10, then push hard plastics catch bar 11 mouse
Gently promote forward, treat the deformable edge of buckle 14 of mouse head contacting metal, stop promoting, open metal variable shape buckle
14, close metal variable shape buckle 14 after mouse head stretches out metal variable shape buckle 14；
Step 3, the double leaf ear hydrojet plastic cap 6 in liquid-transfering device is connected to mouse ear, the choosing of the hydrojet plastics headrest 7
Select according to depending on experimental animal size, micro quantitative determination pipette plastics catch bar 2 is promoted according to required dose, complete quantitative spray
Liquid；
Step 4, metal variable shape buckle 14 is opened after drug effect plays, mouse is slowly released, then carried out follow-up real
Test.
Claims (1)
1. a kind of multifunctional liquid-spraying administration combination unit local for experimental animal, including liquid-transfering device and mouse fix dress
To put, it is characterised in that liquid-transfering device includes micro quantitative determination liquid relief plastic tube (1), micro quantitative determination pipette plastics catch bar (2),
Metal sealing two-way valve (3), metal nuts interface (4), independence etc. hold diplopore plastic hose (5), double leaf ear plastics jet head
(6) can be moved with the plastics hydrojet headrest (7), micro quantitative determination pipette plastics catch bar (2) in micro quantitative determination liquid relief plastic tube (1)
Dynamic, micro quantitative determination liquid relief plastic tube (1) head is provided with the appearance diplopore plastic hose such as metal nuts interface (4), independence (5) and passes through gold
Category sealing two-way valve (3) is connected with metal nuts interface (4), and the plastics hydrojet headrest (7) is placed in double leaf ear plastics jet head (6)
Interior, double leaf ear plastics jet head (6) is connected with appearance diplopore plastic hoses (5) such as independences；Often set in mouse fixing is consolidated
Determining device includes plastic bottom board (8), independent transparent oval plastic tube (9), plastics door closure (10), plastics catch bar (11), modeling
Expect dividing plate (12), transparent plastic baffle plate (13) and metal variable shape buckle (14), independent transparent oval plastic tube (9) is fixed on
On plastic bottom board (8), it is provided with opening at afterbody, and plastics door closure (10) is placed on this opening, transparent plastic baffle plate (13)
Independent transparent oval plastic tube (9) head is located at, plastics catch bar (11) is inserted from independent transparent oval plastic tube (9) afterbody
Enter and can move back and forth in it, metal variable shape buckle (14) is fixed on transparent plastic baffle plate (13), per sleeve fixture mechanism
Separated respectively with plastic septum (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610522058.1A CN106037988B (en) | 2016-07-05 | 2016-07-05 | A kind of multifunctional liquid-spraying administration combination unit local for experimental animal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610522058.1A CN106037988B (en) | 2016-07-05 | 2016-07-05 | A kind of multifunctional liquid-spraying administration combination unit local for experimental animal |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106037988A CN106037988A (en) | 2016-10-26 |
| CN106037988B true CN106037988B (en) | 2018-01-05 |
Family
ID=57200973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610522058.1A Active CN106037988B (en) | 2016-07-05 | 2016-07-05 | A kind of multifunctional liquid-spraying administration combination unit local for experimental animal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106037988B (en) |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5037399A (en) * | 1989-07-07 | 1991-08-06 | Reichert Elmer L | Apparatus for the administration of medications to animals |
| CN101455588A (en) * | 2008-12-10 | 2009-06-17 | 南京医科大学第一附属医院 | Animal smoking device for experiment |
| CN101637411A (en) * | 2009-08-12 | 2010-02-03 | 大连大学 | Tiny vein injection drug delivery system on body surface of experimental animal |
| CN201831975U (en) * | 2010-11-01 | 2011-05-18 | 东北农业大学 | Gavage apparatus for poultry |
| CN202005815U (en) * | 2011-02-22 | 2011-10-12 | 山东大学 | Heat-preservation fixing table for blood-taking and injecting of blood vessels at tail of big/small mouse for experiment |
| CN202477898U (en) * | 2012-04-09 | 2012-10-10 | 黑龙江农垦职业学院 | Animal gavage feeding device capable of monitoring liquid drug temperature in real time |
| CN203001166U (en) * | 2013-01-16 | 2013-06-19 | 朱宇 | Experimental mouse fixing device for caudal intravenous administration |
| CN203634330U (en) * | 2014-01-06 | 2014-06-11 | 黑龙江省兽医科学研究所 | Veterinary multifunctional injection medicine supply apparatus |
| CN204446177U (en) * | 2015-03-04 | 2015-07-08 | 中国长江三峡集团公司中华鲟研究所 | A kind of catheter type fish syringe |
| CN205031387U (en) * | 2015-09-16 | 2016-02-17 | 张超奇 | Mouse fixing device for experiments |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003518421A (en) * | 1999-12-27 | 2003-06-10 | アルザ・コーポレーション | Osmotic beneficial agent delivery system |
| DE20210683U1 (en) * | 2002-07-10 | 2002-10-17 | Henke Sass Wolf Gmbh | Veterinary syringe |
-
2016
- 2016-07-05 CN CN201610522058.1A patent/CN106037988B/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5037399A (en) * | 1989-07-07 | 1991-08-06 | Reichert Elmer L | Apparatus for the administration of medications to animals |
| CN101455588A (en) * | 2008-12-10 | 2009-06-17 | 南京医科大学第一附属医院 | Animal smoking device for experiment |
| CN101637411A (en) * | 2009-08-12 | 2010-02-03 | 大连大学 | Tiny vein injection drug delivery system on body surface of experimental animal |
| CN201831975U (en) * | 2010-11-01 | 2011-05-18 | 东北农业大学 | Gavage apparatus for poultry |
| CN202005815U (en) * | 2011-02-22 | 2011-10-12 | 山东大学 | Heat-preservation fixing table for blood-taking and injecting of blood vessels at tail of big/small mouse for experiment |
| CN202477898U (en) * | 2012-04-09 | 2012-10-10 | 黑龙江农垦职业学院 | Animal gavage feeding device capable of monitoring liquid drug temperature in real time |
| CN203001166U (en) * | 2013-01-16 | 2013-06-19 | 朱宇 | Experimental mouse fixing device for caudal intravenous administration |
| CN203634330U (en) * | 2014-01-06 | 2014-06-11 | 黑龙江省兽医科学研究所 | Veterinary multifunctional injection medicine supply apparatus |
| CN204446177U (en) * | 2015-03-04 | 2015-07-08 | 中国长江三峡集团公司中华鲟研究所 | A kind of catheter type fish syringe |
| CN205031387U (en) * | 2015-09-16 | 2016-02-17 | 张超奇 | Mouse fixing device for experiments |
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| Publication number | Publication date |
|---|---|
| CN106037988A (en) | 2016-10-26 |
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