CN101455588A - Animal smoking device for experiment - Google Patents
Animal smoking device for experiment Download PDFInfo
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- CN101455588A CN101455588A CNA2008102436151A CN200810243615A CN101455588A CN 101455588 A CN101455588 A CN 101455588A CN A2008102436151 A CNA2008102436151 A CN A2008102436151A CN 200810243615 A CN200810243615 A CN 200810243615A CN 101455588 A CN101455588 A CN 101455588A
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Abstract
The present invention relates to an experiment device, and especially relates to an animal experiment device, which belongs to the technical field of medical sanitation experiment. The device according to the invention comprises a frame. A fixed rod and a syringe barrel are installed on the frame. The fixed rod is sleeved with a movable plate. The base of movable plate is connected with the syringe push rod in the syringe barrel. An animal chamber is installed at the base of frame. The injection opening of syringe barrel is communicated with a first opening of smoking three-way pipe. A second opening of smoking three-way pipe is communicated with a cigarette holder. A third opening of the smoking three-way pipe is communicated with the animal chamber. The communicating channel between the injection opening and the animal chamber is installed with a first consequent one-way valve. The communicating channel between the injection opening and the cigarette holder is installed with a second antidromic one-way valve. The experiment device of the invention has the beneficial effect that the smoking process of people is simulated and the operation is convenient. The motor can operate repeatedly. Furthermore the number of cigarette smoked by each animal can be counted. The effect of different smoking degree to the animal body is facilitated. The cost is low and the using is safe.
Description
Technical field
The present invention relates to a kind of experimental provision, especially a kind of animal experiment device capable belongs to health care experimental technique field.
Background technology
Smoking is a worldwide problem, and China is tobacco consumption big country, and China smoker is about 3.5 hundred million at present, occupies first of the countries in the world.But smoking can cause various diseases, comprises pulmonary carcinoma, obstructive pulmonary disease, pulmonary fibrosis and cardiovascular and cerebrovascular disease etc.According to statistics, China's number of dying from the Nicotiana tabacum L. relevant disease every year reaches 1,000,000.Therefore, actively propaganda smoking cessation and to carry out the scientific research of relevant smoking very important.Experimentation for smoking is mainly finished by means of the smoking animal model, but still there is not very good animal smoking device so far, so researcheres adopt animal smoking method separately, the animal smoking model of setting up is also different, and document sees reference: 1. in emerald green fragrant, and Wang Wei, Zhang Zhongling, Deng. ambroxol is to the influence of IL-8 TNF-α among smoking bronchus of rat mucosa ultrastructure and the BALF. cardiopulmonary angiopathy magazine, 2007,26 (4): 229-232.Liu Wen and, thunder brilliance, Li Kanghua, etc. the dependency of passive smoking rat bone amount and bone biomechanical index and the intervention effect of epimedium flavone. Chinese Tissue Engineering Study and clinical rehabilitation, 2008,12 (20): 3905-3909.3. Li Weiwen, Li Yunliang. the experimentation of relation is split in passive smoking and congenital lip Hubei Province. clinical stomatology magazine, 2003,19 (1): 45-47.4. permitted Mibayashi, Wu Renliang, Chen Chunlian. the research that the epithelium cadherin is expressed in smoking mice airway epithelial injury repairing. Chinese tuberculosis and breathing magazine, 1999,22 (7): 417.5. Liu Zhi is gorgeous, Sui Shaofeng, and Wang Zhifu, etc. smoking damages Study on Mechanism to airway epithelial, Chinese public health, 2005,21 (8): 897-899.By document as can be known, the degree of animal smoking and the quality of model thereof can't guarantee and unify at present, have restricted the smoking progress of research, therefore, press for the reliable laboratory animal smoking apparatus of a kind of ideal, for smoking research facilitates.
Summary of the invention
The present invention wants the technical solution problem to be: the shortcoming at above prior art exists proposes a kind of animal smoking device for experiment easy for operation, thereby the experimental provision of science is provided for smoking research.
In order to solve above technical problem, animal smoking device for experiment of the present invention comprises framework, described framework is equipped with fixed bar and injector cartridge, suit portable plate on the described fixed bar, the bottom of described portable plate be inserted into the intravital injector push-rod of syringe cylinder and link to each other, the bottom of described framework is provided with the animal storehouse, and the injection port of described injector cartridge is communicated with first interface of smoking three-way pipeline; Second interface of described smoking three-way pipeline is communicated with cigarette holder, and the 3rd interface of described smoking three-way pipeline is communicated with the animal storehouse; Be provided with first check valve forward in the communication passage between described injection port and the animal storehouse, be provided with the second reverse check valve in the communication passage between described injection port and the cigarette holder.
During experiment, the medicated cigarette of lighting is placed in the cigarette holder, will treats that laboratory animal puts into the animal storehouse.The manipulation activities plate moves along fixed bar and can drive push rod easily and do piston move in injector cartridge.When the intravital volume of tube enlarges, by the smog suction cylindrical shell of first check valve with the cigarette holder place; When the intravital volume of tube dwindles, cigarette smog is expelled to the animal storehouse by second check valve.By the original scale of syringe, can control amount of smoke as required, thereby create ideal condition for carrying out required animal smoking scientific experiments.
It is that the outfan of described portable plate and linear motor is in transmission connection, and can finish the suction and the injection of smog like this by on-off control automatically that the present invention further improves.
The invention has the beneficial effects as follows: can simulate the human body smoking process, smog quantitatively is injected in the animal storehouse, force animal to suck respiratory tract, easy to operate, motor can be worked repeatedly and every animal suction number of cigarettes can be added up, help to study the influence that different smoking degree produce animal body, its cost economy, safe in utilization.
Description of drawings
The present invention is further illustrated below in conjunction with accompanying drawing.
Fig. 1 is the structural representation of one embodiment of the invention.
Fig. 2 is the partial structurtes sketch map of Fig. 1.
Fig. 3 is a working state schematic representation of the embodiment of the invention.
Fig. 4 is another working state schematic representation of the embodiment of the invention.
The specific embodiment
Embodiment one
As shown in Figure 1 and Figure 2, the animal smoking device for experiment of present embodiment comprises framework 1, and vertical fixed bar 4 is equipped with in framework 1 both sides, and one group of injector cartridge 12 is equipped with at the middle part, by sleeve pipe 5 suit portable plates 2 (portable plate 2 is connected with sleeve pipe 5), constitute moving sets on the fixed bar 4.The bottom of portable plate 2 links to each other with injector push-rod 11 in being inserted into injector cartridge 12.The bottom of framework 1 is provided with animal storehouse 10.The injection port of injector cartridge 12 is communicated with first interface of smoking three-way pipeline 13; Second interface of smoking three-way pipeline 13 is communicated with cigarette holder 8, and flue dust pallet 9 is placed in the below of cigarette holder 8, and the 3rd interface of smoking three-way pipeline 13 is communicated with animal storehouse 10, and injector cartridge 12 interfixes by crosspiece bar 6 and screw 7.Be provided with first check valve 14 forward in the communication passage between injection port and the animal storehouse 10, be provided with the second reverse check valve 15 in the communication passage between injection port and the cigarette holder 8.
As shown in Figure 3, Figure 4, during the suction syringe, first one-way valve opens, second closed check valve, cigarette is inhaled into syringe; During the bolus infusion device, first closed check valve, second one-way valve opens, cigarette is injected into the animal storehouse.If the outfan of portable plate and linear motor is in transmission connection, finish the suction and the injection of smog automatically by on-off control, then can further improve the device of present embodiment.
In addition to the implementation, the present invention can also have other embodiments, for example adopts single syringe etc. in the device.All employings are equal to the technical scheme of replacement or equivalent transformation formation, all drop on the protection domain of requirement of the present invention.
Claims (5)
1. animal smoking device for experiment, it is characterized in that: comprise framework, described framework is equipped with fixed bar and injector cartridge; Suit portable plate on the described fixed bar, the bottom of described portable plate be inserted into the intravital injector push-rod of syringe cylinder and link to each other; The bottom of described framework is provided with the animal storehouse, and the injection port of described injector cartridge is communicated with first interface of smoking three-way pipeline; Second interface of described smoking three-way pipeline is communicated with cigarette holder, and the 3rd interface of described smoking three-way pipeline is communicated with the animal storehouse; Be provided with first check valve forward in the communication passage between described injection port and the animal storehouse, be provided with the second reverse check valve in the communication passage between described injection port and the cigarette holder.
2. animal smoking device for experiment according to claim 1 is characterized in that: the outfan of described portable plate and linear motor is in transmission connection.
3. animal smoking device for experiment according to claim 1 and 2 is characterized in that: described portable plate and sleeve pipe are connected, and by sleeve pipe suit portable plate, constitute moving sets on the described fixed bar.
4. animal smoking device for experiment according to claim 3 is characterized in that: one group of syringe is housed in the described framework, and the cylindrical shell of described each syringe interfixes by the crosspiece bar.
5. animal smoking device for experiment according to claim 4 is characterized in that: pallet is placed in described cigarette holder below.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102436151A CN101455588A (en) | 2008-12-10 | 2008-12-10 | Animal smoking device for experiment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102436151A CN101455588A (en) | 2008-12-10 | 2008-12-10 | Animal smoking device for experiment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101455588A true CN101455588A (en) | 2009-06-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008102436151A Pending CN101455588A (en) | 2008-12-10 | 2008-12-10 | Animal smoking device for experiment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101455588A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102935018A (en) * | 2012-11-13 | 2013-02-20 | 天津开发区合普工贸有限公司 | Animal experiment device for passive smoke produced by human smoking |
| CN106037988A (en) * | 2016-07-05 | 2016-10-26 | 大连大学 | Multifunctional liquid-spraying dosing combination device for part of laboratory animal |
| CN107094662A (en) * | 2017-06-27 | 2017-08-29 | 金华市农业科学研究院 | A kind of method that combination box control bucket supports apis cerana natural swarm |
-
2008
- 2008-12-10 CN CNA2008102436151A patent/CN101455588A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102935018A (en) * | 2012-11-13 | 2013-02-20 | 天津开发区合普工贸有限公司 | Animal experiment device for passive smoke produced by human smoking |
| CN102935018B (en) * | 2012-11-13 | 2014-11-26 | 天津开发区合普工贸有限公司 | Animal experiment device for passive smoke produced by human smoking |
| CN106037988A (en) * | 2016-07-05 | 2016-10-26 | 大连大学 | Multifunctional liquid-spraying dosing combination device for part of laboratory animal |
| CN106037988B (en) * | 2016-07-05 | 2018-01-05 | 大连大学 | A kind of multifunctional liquid-spraying administration combination unit local for experimental animal |
| CN107094662A (en) * | 2017-06-27 | 2017-08-29 | 金华市农业科学研究院 | A kind of method that combination box control bucket supports apis cerana natural swarm |
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Legal Events
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090617 |