CN105999215A - Traditional Chinese medicine spray for promoting hair growth and preparation method thereof - Google Patents
Traditional Chinese medicine spray for promoting hair growth and preparation method thereof Download PDFInfo
- Publication number
- CN105999215A CN105999215A CN201610491224.6A CN201610491224A CN105999215A CN 105999215 A CN105999215 A CN 105999215A CN 201610491224 A CN201610491224 A CN 201610491224A CN 105999215 A CN105999215 A CN 105999215A
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- Prior art keywords
- percent
- traditional chinese
- chinese medicine
- promoting
- growth
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- Pending
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Classifications
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Landscapes
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Abstract
The invention discloses traditional Chinese medicine spray for promoting hair growth. The spray is prepared from the following raw materials in percentage by mass: 10-30 percent of traditional Chinese medicine alcohol extract, 1-3 percent of pullulan, 0.5-1 percent of vitamin E, 3-5 percent of hydroxypropyl methyl cellulose, 1-3 percent of camphor, 3-5 percent of cocamidopropyl betaine, 8-12 percent of propylene glycol, 0.3-0.5 percent of avocado oil, 0.5-1 percent of hydrolyzed wheat protein, 0.1-0.2 percent of methylisothiazolinone, 0.1-0.3 percent of menthol, 0.1-0.3 percent of preservative, 0.5-1 percent of L-cystine, 0.1-0.3 percent of zinc gluconate and the balance of deionized water. The traditional Chinese medicine spray is reasonable in compatibility and convenient to use, has good using comfort, high safety, long acting time and good curative effect, and can be used for effectively promoting hair growth and inhibiting alopecia, grease secretion and dandruffregeneration. The invention further discloses a method for preparing the traditional Chinese medicine spray for promoting hair growth. The method is simple in process steps, does not have special requirement for equipment, has strong operability and is suitable for large-scale popularization and application.
Description
Technical field
The present invention relates to a kind of hair growth promoter, especially relate to a kind of growth-promoting and send out Traditional Chinese medicinal spray and preparation method thereof.
Background technology
With the quickening pace of modern life, the increasing of operating pressure, increasing artificial alopecia and worried.Alopecia broad categories, type are more, and situation is different, common are alopecia areata, male pattern alopecia, seborrheic alopecia three kinds.The limitation plaque-like alopecia of alopecia areata system, its feature is that lesion scalp is normal, NIP, no conscious sympton, Chang Yu stumbles on, head has circle or oval alopecia spot, the hair of alopecia area edge is more loose, is drawn out easily very much, and the course of disease sustainable several months of alopecia areata is to the several years, big multipotency spontaneous recovery, but also have recurrent exerbation；It is between twenty and fifty that male pattern alopecia is apt to occur in male, and is more common in brain worker, and hair is dried shortage gloss；Seborrheic alopecia, is also more common in male adults, and scalp is the most greasy shinny or has a large amount of dandruff, in canescence pityrosporum shape, conscious scratching where it itches, time permanent forehead both sides and head hair start symmetry and come off, sparse attenuating, affected part, due to hair follicle atrophy, frequently results in permanent alopecia.
Owing to hair plays an important role in the appearance of people, being also the index of person health status, therefore hair growth promoter is subject to concern and the attention of more and more consumers simultaneously.Current hair growth promoter can be divided into chemistry hair growth promoter and Chinese herbal medicine hair growth promoter, the safety of chemistry hair growth promoter to be worth discussion, and its effect is single, and Chinese herbal medicine hair growth promoter is of a great variety, and effect differs, in addition it is also necessary to the medicinal herb components that screening is suitable for.It addition, current hair growth promoter is usually lotion or liniment, using more inconvenience, and the time of staying that functional component is in affected part is short, actual efficacy is not notable, brings difficulty to the treatment of patient.
Summary of the invention
The present invention is to solve the above-mentioned technical problem existing for the hair growth promoter of prior art, provide a kind of compatibility reasonable, easy to use, comfort is good with safety, long action time, good effect, can effectively facilitate hair growth and suppress the growth-promoting of alopecia, fat secretion and dandruff regeneration to send out Traditional Chinese medicinal spray.
Present invention also offers a kind of growth-promoting and send out Traditional Chinese medicinal spray preparation method, processing step is simple, to equipment without particular/special requirement, operable by force, be suitable for large-scale promotion application.
To achieve these goals, the present invention is by the following technical solutions:
A kind of growth-promoting of the present invention sends out Traditional Chinese medicinal spray, it is made up of the raw material of following mass percent: Chinese medicine ethanol extract 10 ~ 30%, pulullan polysaccharide 1 ~ 3%, vitamin E 0.5 ~ 1%, hydroxypropyl methyl cellulose 3 ~ 5%, Camphora 1 ~ 3%, cocamido propyl betaine 3 ~ 5%, propylene glycol 8 ~ 12%, American Avocado Tree oil 0.3 ~ 0.5%, hydrolyzed wheat protein 0.5 ~ 1%, Methylisothiazolinone 0.1 ~ 0.2%, menthol 0.1 ~ 0.3%, preservative 0.1 ~ 0.3%, CYSTINE 0.5 ~ 1%, zinc gluconate 0.1 ~ 0.3%, surplus is deionized water.It is easy to use that the growth-promoting of the present invention sends out Traditional Chinese medicinal spray, compatibility is reasonable, and wherein pulullan polysaccharide is the outer water solublity cement polysaccharide of born of the same parents, and has certain viscosity, it is that the present invention can be evenly affixed at spraying, it is attached to affected part for a long time, and the functional component in the present invention can be adsorbed, so that the retention time that functional component is in affected part is longer, it is greatly prolonged the action time of functional component, improve using effect, thus it is short to efficiently solve the functional component time of staying in affected part, actual efficacy inapparent problem；Hydrolyzed wheat protein can help to promote the protein expression that those are relevant to hair new life, finally it is divided into various full-time cell and supports natural on-off cycles of hair growth and renewal, by the Synergistic between Chinese medicine ethanol extract, hydrolyzed wheat protein, CYSTINE and zinc gluconate several effect component, energy enriched nutritive, strengthen cellular metabolism function, improve blood microcirculation, make telangiectasis, play and stimulate hair growth promoting and promote the effect of human hair growth, and effectively suppress alopecia, fat secretion and dandruff regeneration；Cocamido propyl betaine is dispersed after the present invention can be made to spray；American Avocado Tree oil has stronger osmosis, permeable layer, can strengthen curative effect, can repair damaged skin, beneficially hair regrowth simultaneously；Menthol has the effects such as antipruritic, refrigerant, antiinflammatory, also has permeation enhancers effect, can promote that effective ingredient enters skin, improve using effect；Hydroxypropyl methyl cellulose plays the effect of stabilizer suspending agent, is that in the present invention, each component keeps homogeneous, stable；There is when the present invention uses certain burning sensation, therefore for improving comfort, the present invention has been intentionally added menthol and vitamin E, wherein menthol has refrigerant effect, burning sensation can be reduced, vitamin E plays and moistens and the effect of skin protection, and after can significantly reducing use, produced dry and astringent and burning sensation, improves comfort.The present invention is optimized improvement to whole basic components, the reasonable science of formula, each material performance is gentleer, and the stability of whole system is good with safety, each component coordinated, easy to use, comfort is good with safety, long action time, eutherapeutic can stimulate hair growth promoting, hair growth can be effectively facilitated and suppress alopecia, fat secretion and dandruff regeneration, and it is short to solve the functional component time of staying in affected part, actual efficacy inapparent problem.
As preferably, described Chinese medicine ethanol extract prepares by the following method: by 40 ~ 50 portions of Rhizoma Zingiberis Recenss, 20 ~ 30 parts of drynaria baroniis, 10 ~ 20 portions of Fructus Zanthoxylis, 3 ~ 5 portions of Herba Ecliptaes, 1 ~ 3 part of Bombyx mori L., 5 ~ 10 portions of Aloes, 15 ~ 20 parts of Folium Mori, 10 ~ 15 parts of Fructus Vaccinii Bracteati, 15 ~ 20 portions of Cacumen Platycladis, 40 ~ 50 parts of Flos Carthamis, 10 ~ 15 parts of Fructus Psoraleaes, 5 ~ 10 parts of SUIGUBU, 5 ~ 10 parts of Radix Angelicae Sinensis, 15 ~ 20 parts of Radixs Astragali, after the weight portion of 5 ~ 10 portions of Radix Glycyrrhizaes weighs each raw material, it is incorporated as 65% ethanol water of raw material gross mass 20 ~ 30 times, after soaking at least one week, filters, sterilizing, obtains Chinese medicine ethanol extract.In the Chinese medicine ethanol extract side of the present invention, meticulously having screened plurality of Chinese component, medicine source is rationally enriched, without any side effects, and Radix Angelicae Sinensis, Flos Carthami energy nourshing blood and promoting blood circulation, stimulate the menstrual flow row arteries and veins；Cacumen Platycladi, Folium Mori can expelling wind and clearing away heat dehumidifying, anti-inflammations；Fructus Vaccinii Bracteati, Rhizoma Zingiberis Recens, drynaria baronii, Fructus Zanthoxyli and Bombyx mori L. play that supporing yang temperature is logical, expelling wind and removing dampness altogether, expelling wind and removing dampness, promoting blood circulation to restore menstrual flow loosing the interspaces of skin and muscles, growth-promoting deed as tiny as hair；Fructus Psoraleae, SUIGUBU can blood circulation promoting and blood stasis dispelling, promote local blood follow, nutrition hair；The Radix Astragali can tonifying Qi and lifting yang, benefiting QI for strengthening the superficies；Aloe can promote scalp blood circulation and metabolism, supplements the nutrients for hair papilla, and promotes the scalp rehabilitation having damage thoughts dye, and the oils and fats of minimizing oily hair overflows, and promotes that new sending out regenerates；Radix Glycyrrhizae then plays coordinating the actions of various ingredients in a prescription effect.Chinese medicine ethanol extract safety of the present invention is good, and each component coordinated brings out the best in each other, has warm, fills blood, the meridian dredging, and blood circulation promoting excites pore to expand, and promotes the specially good effect of hair growth.
As preferably, soak after each raw material pulverizing.
As preferably, during immersion, stirred once every 2 ~ 3 days.
A kind of growth-promoting sends out Traditional Chinese medicinal spray preparation method, concretely comprise the following steps: after weighing each component by proportioning, deionized water is heated to 40 ~ 50 DEG C, add hydroxypropyl methyl cellulose and cocamido propyl betaine, stir, be subsequently added into vitamin E, propylene glycol, American Avocado Tree oil, Methylisothiazolinone and menthol, room temperature it is cooled to after stirring, add remaining ingredient, stir, obtain growth-promoting and send out Traditional Chinese medicinal spray.In the preparation method of the present invention, emphasis one is: by controlling the order of addition of each raw material, thus to ensure mixing uniformity and the stability of each component；Emphasis two is: ensureing on the premise of each component dissolubility, controls to add temperature less than 50 DEG C, in order to avoid affecting effect of active component, even causes product variable color, spoiled.
Therefore, there is advantages that
(1) provide a kind of growth-promoting and send out Traditional Chinese medicinal spray, whole basic components is optimized improvement, the reasonable science of formula, each material performance is gentleer, the stability of whole system is good with safety, each component coordinated, easy to use, comfort is good with safety, long action time, eutherapeutic can stimulate hair growth promoting, can effectively facilitate hair growth and suppress alopecia, fat secretion and dandruff regeneration, and it is short to solve the functional component time of staying in affected part, actual efficacy inapparent problem；
(2) processing step is simple, workable, to equipment without particular/special requirement, is suitable for industrialized production, by controlling order of addition and the charge temperature of each raw material, it is ensured that the mixing uniformity of each component and stability, it is to avoid affect effect of active component.
Detailed description of the invention
Below by detailed description of the invention, the present invention will be further described.
In the present invention, if not refering in particular to, all percentage ratios are unit of weight, all devices and raw material and are all commercially available or the industry is conventional, the method in following embodiment, if no special instructions, are this area conventional method.
Embodiment 1
(1) 50kg Rhizoma Zingiberis Recens, 30kg drynaria baronii, 20kg Fructus Zanthoxyli, 5kg Herba Ecliptae are pressed, 3kg Bombyx mori L., 10kg Aloe, 20kg Folium Mori, 15kg Fructus Vaccinii Bracteati, 20kg Cacumen Platycladi, 50kg Flos Carthami, 15kg Fructus Psoraleae, 10kg SUIGUBU, 10kg Radix Angelicae Sinensis, the 20kg Radix Astragali, after the weight proportion of 10kg Radix Glycyrrhizae weighs each raw material, 65% ethanol water of raw material gross mass 30 times will be incorporated as after each raw material pulverizing, soaked at least one week, during immersion every stirring in 3 days once, filter, sterilizing, obtain Chinese medicine ethanol extract；
(2) Chinese medicine ethanol extract 30% is pressed, pulullan polysaccharide 3%, vitamin e1 %, hydroxypropyl methyl cellulose 5%, Camphora 3%, cocamido propyl betaine 5%, propylene glycol 12%, American Avocado Tree oil 0.5%, hydrolyzed wheat protein 1%, Methylisothiazolinone 0.2%, menthol 0.3%, preservative 0.3%, CYSTINE 1%, zinc gluconate 0.3%, after surplus is the mass percent each component of metering of deionized water, deionized water is heated to 50 DEG C, add hydroxypropyl methyl cellulose and cocamido propyl betaine, stir, it is subsequently added into vitamin E, propylene glycol, American Avocado Tree oil, Methylisothiazolinone and menthol, room temperature it is cooled to after stirring, add remaining ingredient, stir, obtain growth-promoting and send out Traditional Chinese medicinal spray.
Embodiment 2
(1) 40kg Rhizoma Zingiberis Recens, 20kg drynaria baronii, 10kg Fructus Zanthoxyli, 3kg Herba Ecliptae are pressed, 1kg Bombyx mori L., 5kg Aloe, 15kg Folium Mori, 10kg Fructus Vaccinii Bracteati, 15kg Cacumen Platycladi, 40kg Flos Carthami, 10kg Fructus Psoraleae, 5kg SUIGUBU, 5kg Radix Angelicae Sinensis, the 15kg Radix Astragali, after the weight proportion of 5kg Radix Glycyrrhizae weighs each raw material, 65% ethanol water of raw material gross mass 20 times will be incorporated as after each raw material pulverizing, soaked at least one week, during immersion every stirring in 2 days once, filter, sterilizing, obtain Chinese medicine ethanol extract；
(2) Chinese medicine ethanol extract 10% is pressed, pulullan polysaccharide 1%, vitamin E 0.5%, hydroxypropyl methyl cellulose 3%, Camphora 1%, cocamido propyl betaine 3%, propylene glycol 8%, American Avocado Tree oil 0.3%, hydrolyzed wheat protein 0.5%, Methylisothiazolinone 0.1%, menthol 0.1%, preservative 0.1%, CYSTINE 0.5%, zinc gluconate 0.1%, after surplus is the mass percent each component of metering of deionized water, deionized water is heated to 40 DEG C, add hydroxypropyl methyl cellulose and cocamido propyl betaine, stir, it is subsequently added into vitamin E, propylene glycol, American Avocado Tree oil, Methylisothiazolinone and menthol, room temperature it is cooled to after stirring, add remaining ingredient, stir, obtain growth-promoting and send out Traditional Chinese medicinal spray.
Embodiment 3
(1) 45kg Rhizoma Zingiberis Recens, 25kg drynaria baronii, 15kg Fructus Zanthoxyli, 4kg Herba Ecliptae are pressed, 2kg Bombyx mori L., 7kg Aloe, 18kg Folium Mori, 12kg Fructus Vaccinii Bracteati, 18kg Cacumen Platycladi, 45kg Flos Carthami, 12kg Fructus Psoraleae, 8kg SUIGUBU, 8kg Radix Angelicae Sinensis, the 18kg Radix Astragali, after the weight proportion of 7kg Radix Glycyrrhizae weighs each raw material, 65% ethanol water of raw material gross mass 25 times will be incorporated as after each raw material pulverizing, soaked at least one week, during immersion every stirring in 2 days once, filter, sterilizing, obtain Chinese medicine ethanol extract；
(2) Chinese medicine ethanol extract 20% is pressed, pulullan polysaccharide 2%, vitamin E 0.8%, hydroxypropyl methyl cellulose 4, Camphora 2%, cocamido propyl betaine 4%, propylene glycol 10%, American Avocado Tree oil 0.4%, hydrolyzed wheat protein 0.7%, Methylisothiazolinone 0.15%, menthol 0.2%, preservative 0.2%, CYSTINE 0.7%, zinc gluconate 0.2%, after surplus is the mass percent each component of metering of deionized water, deionized water is heated to 45 DEG C, add hydroxypropyl methyl cellulose and cocamido propyl betaine, stir, it is subsequently added into vitamin E, propylene glycol, American Avocado Tree oil, Methylisothiazolinone and menthol, room temperature it is cooled to after stirring, add remaining ingredient, stir, obtain growth-promoting and send out Traditional Chinese medicinal spray.
The using effect of the present invention is further illustrated below by concrete clinical case:
(1) sufferer: choose 68 example sufferers, alopecia areata 38 example, male 30 examples, female 8 example, 19 ~ 62 years old age, the course of disease 2 months ~ 5 years altogether；Wherein alopecia areata person 22 example at 1, alopecia areata person 12 example at 2, > alopecia areata person 4 example at 3；Seborrheic alopecia 30 example, male 18 examples, women 12 example, 20 ~ 65 years old age, the course of disease 6 months ~ 3 years.First 2 months unused hair growth promoting class medicines excessively and sugar cortical hormone.
Element etc..
(2) using method: by affected part with after clear water wash clean, takes the growth-promoting of the present invention and sends out Traditional Chinese medicinal spray direct spraying in affected part, and spraying in every two days once, two months is 1 course for the treatment of, uses 1 course for the treatment of.
(3) efficacy determination: formulate criterion of therapeutical effect with reference to " guideline of clinical investigations of new Chinese medicine treatment alopecia ".1. alopecia areata criterion of therapeutical effect, recovery from illness: hair stops coming off, newly send out well-grown whole；Effective: hair stops coming off, new sending out regenerates > 70%；Effective: hair stops coming off, and firewood occurs long 30 ~ 70%；Invalid: kainogenesis length < 30% or continue to de-originator.2. seborrheic alopecia criterion of therapeutical effect, recovery from illness: hair stops coming off, substantially without greasy feeling, without pruritus, without desquamation, > have Xin Fa or fine hair on birds or animals hair at 80% skin lesion；Effective: to have kainogenesis long at 60% skin lesion, greasy feeling and lipid desquamation significantly reduce, and pruritus substantially alleviates；Effective: to have kainogenesis long at 30% skin lesion, greasy feeling and lipid desquamation have part to reduce, and pruritus has and alleviates；Invalid: long without kainogenesis, greasy feeling and lipid desquamation are without reducing, and pruritus is without alleviating.
(4) result is used:
Alopecia areata (totally 38 example): 3 examples of fully recovering, effective 28 examples, effective 5 examples, invalid 2 examples, total effective rate 94.7%；
Alopecia seborrheica (30 example): 3 examples of fully recovering, effective 21 examples, effective 4 examples, invalid 2 examples, total effective rate 93.3%.
The present invention 68 example through clinical usage, does not finds that obvious adverse reaction, total effective rate reach 94.1%, good effect of the present invention is described, and the course for the treatment of is shorter, has no side effect, and can effectively facilitate hair growth and suppress alopecia, fat secretion and dandruff regeneration.
Embodiment described above is the one preferably scheme of the present invention, and the present invention not makees any pro forma restriction, also has other variant and remodeling on the premise of without departing from the technical scheme described in claim.
Claims (5)
1. a growth-promoting sends out Traditional Chinese medicinal spray, it is characterized in that, it is made up of the raw material of following mass percent: Chinese medicine ethanol extract 10 ~ 30%, pulullan polysaccharide 1 ~ 3%, vitamin E 0.5 ~ 1%, hydroxypropyl methyl cellulose 3 ~ 5%, Camphora 1 ~ 3%, cocamido propyl betaine 3 ~ 5%, propylene glycol 8 ~ 12%, American Avocado Tree oil 0.3 ~ 0.5%, hydrolyzed wheat protein 0.5 ~ 1%, Methylisothiazolinone 0.1 ~ 0.2%, menthol 0.1 ~ 0.3%, preservative 0.1 ~ 0.3%, CYSTINE 0.5 ~ 1%, zinc gluconate 0.1 ~ 0.3%, surplus is deionized water.
A kind of growth-promoting the most according to claim 1 sends out Traditional Chinese medicinal spray, it is characterized in that, described Chinese medicine ethanol extract prepares by the following method: by 40 ~ 50 portions of Rhizoma Zingiberis Recenss, 20 ~ 30 parts of drynaria baroniis, 10 ~ 20 portions of Fructus Zanthoxylis, 3 ~ 5 portions of Herba Ecliptaes, 1 ~ 3 part of Bombyx mori L., 5 ~ 10 portions of Aloes, 15 ~ 20 parts of Folium Mori, 10 ~ 15 parts of Fructus Vaccinii Bracteati, 15 ~ 20 portions of Cacumen Platycladis, 40 ~ 50 parts of Flos Carthamis, 10 ~ 15 parts of Fructus Psoraleaes, 5 ~ 10 parts of SUIGUBU, 5 ~ 10 parts of Radix Angelicae Sinensis, 15 ~ 20 parts of Radixs Astragali, after the weight portion of 5 ~ 10 portions of Radix Glycyrrhizaes weighs each raw material, it is incorporated as 65% ethanol water of raw material gross mass 20 ~ 30 times, after soaking at least one week, filter, sterilizing, obtain Chinese medicine ethanol extract.
A kind of growth-promoting the most according to claim 2 sends out Traditional Chinese medicinal spray, it is characterised in that soak after each raw material pulverizing.
4. send out Traditional Chinese medicinal spray according to a kind of growth-promoting described in Claims 2 or 3, it is characterised in that during immersion, every stirring in 2 ~ 3 days once.
5. a growth-promoting as claimed in claim 1 sends out Traditional Chinese medicinal spray preparation method, it is characterized in that, concretely comprise the following steps: after weighing each component by proportioning, deionized water is heated to 40 ~ 50 DEG C, add hydroxypropyl methyl cellulose and cocamido propyl betaine, stir, it is subsequently added into vitamin E, propylene glycol, American Avocado Tree oil, Methylisothiazolinone and menthol, after stirring, is cooled to room temperature, add remaining ingredient, stir, obtain growth-promoting and send out Traditional Chinese medicinal spray.
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Application publication date: 20161012 |