CN105999066A - Formulation for treating osteocomma aches - Google Patents

Formulation for treating osteocomma aches Download PDF

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Publication number
CN105999066A
CN105999066A CN201610452732.3A CN201610452732A CN105999066A CN 105999066 A CN105999066 A CN 105999066A CN 201610452732 A CN201610452732 A CN 201610452732A CN 105999066 A CN105999066 A CN 105999066A
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Prior art keywords
radix
rhizoma
herba
achyranthis bidentatae
caulis
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CN201610452732.3A
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不公告发明人
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Cui Kunfeng
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Priority to CN201610452732.3A priority Critical patent/CN105999066A/en
Publication of CN105999066A publication Critical patent/CN105999066A/en
Priority to PCT/CN2017/097782 priority patent/WO2017220047A2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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Abstract

The invention discloses a formulation for treating osteocomma aches. The formulation comprises oral taking formulation components and external thermal therapy components. The oral taking formulation components comprise, by weight, 1 g to 10 g of poria cocos, 1 g to 10 g of milkvetch roots, 1 g to 10 g of the fruit of Chinese magnoliavine, 1 g to 10 g of radix codonopsis, 5 g to 15 g of goat bones, 5 g to 20 g of bovine bone marrow, 1 g to 15 g of longstamen onion bulb, 1 g to 10 g of fructus aurantii, 1 g to 15 g of peach kernels, 1 g to 15 g of radix notoginseng,1 g to 5 g of folium ginkgo, 1 g to 15 g of sberect spatholobus stems and 1 g to 15 g of plantain herb. The external thermal therapy components comprise, by weight, 5 g to 25 g of the rhizome of Chinese atractylode, 5 g to 15 g of sberect spatholobus stems, 1 g to 20 g of semen strychni, 5 g to 15 g of plantain herb, 5 g to 10 g of ginger slices, 5 g to 10 g of dried tangerine or orange peel and 5 g to 10 g of radix bupleuri. According to the formulation for treating the osteocomma aches, internal and external medicine application is carried out through an oral taking and external local thermal therapy mode, so that the good treatment effect is improved; the pain of the disease portion can be relieved through the oral taking formulation components; meanwhile, the mode of replacing nourishing with dredging is adopted for treating qi and blood retardation and extravasated blood agglomeration; in addition, the immunity and the metabolism capacity can be improved, and the probability of relapse can be reduced.

Description

One is treated joint and is ached formula
Technical field
The present invention relates to one and treat rheumatism formula, be specifically related to one and treat joint and ache and join Side, belongs to Chinese medicine formula technical field.
Background technology
Joint is ached usually by reasons such as traumatic injury sprain and contusion, articular sprain, external force damages, causes QI and blood retardance, congestion cohesion, thus muscle, muscle arteries and veins, the swelling of local joint, pain occur, Apathetic；Chinese Patent Application No.: 201010201469.3 disclose one for interior disease The Chinese medicine composition of outer disease treatment, it is characterised in that be made up by fry of following raw material components: The Radix Aucklandiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Rehmanniae etc.；The invention still further relates to the preparation side of described Chinese medicine composition Method and in the medicine that such as wind and cold dampness, numb hand and foot, joint are ached etc. is treated in preparation should With；It is strong that its versatility compares chamber, but the treatment of the formula of neither one system that joint is ached.
Summary of the invention
For solving the problems referred to above, the present invention proposes one and treats joint and ache formula, it is possible to live Blood and relieving pain, reduce uric acid, dredging grain and health invigorating and supplement the nutrients to joint, it is to avoid be multiple Send out.
The treatment joint of the present invention is ached formula, and described formula constituent is measured as follows in gram: Semen Coicis Core 5～20g, Rhizoma Smilacis Glabrae 5～20g, Herba Plantaginis 5～10g, Radix Et Rhizoma Rhei 1～10g, Rhizoma Atractylodis 5～20 G, Poria 5～10g, the Radix Astragali 5～10g, Fructus Schisandrae Chinensis 5～10g, Radix Codonopsis 1～5g, pearl white 1～5g, Os Caprae seu Ovis 5～20g, Medulla Bovis seu Bubali 5～20g, Herba Abri 5～10g, Caulis Spatholobi 5～20g, Caulis Lonicerae 5～10g, Radix Tripterygii Wilfordii 1～3g, Herba speranskiae tuberculatae 5～10g, Rhizoma Curcumae Longae 5～10g, Fructus Zanthoxyli 5～10g, river Radix Achyranthis Bidentatae 1～5g, Olibanum 1～5g, Myrrha 5～10g, Flos Carthami 1～5g, bluish glaucoma Rattan 5～10g, Radix Notoginseng 5～10g, Lignum Sappan 5～10g and Radix Achyranthis Bidentatae 5～20g, it can be complete Become a process taken stopgap measures and effect a permanent cure, treat for source of disease, therapeutic process can drop complete Viscosity of blood, platelet adhesion reaction and Platelet, promoting blood circulation and stopping pain, can drop in blood degree； By promoting urate excretion, reduce uric acid, in conjunction with dredging grain, it is possible to make to dredge at joint, Mend with unifier；Simultaneously can carry out the kidney invigorating and replenish the calcium, health invigorating and to joint extra-nutrition, Avoid recurrence.
As preferred embodiment, described formula constituent is measured as follows in gram: Semen Coicis 10g, Rhizoma Smilacis Glabrae 10g, Herba Plantaginis 5g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 10g, Poria 5g, the Radix Astragali 5 G, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Os Gallus domesticus Grass 5g, Caulis Spatholobi 5g, Caulis Lonicerae 5g, Radix Tripterygii Wilfordii 1g, Herba speranskiae tuberculatae 10g, Rhizoma Curcumae Longae 10 G, Fructus Zanthoxyli 10g, river Radix Achyranthis Bidentatae 5g, Olibanum 5g, Myrrha 10g, Flos Carthami 5g, Caulis Sinomenii 10g, Radix Notoginseng 10g, Lignum Sappan 10g and Radix Achyranthis Bidentatae 20g, its primary efficacy promoting blood circulation and stopping pain, Therapeutic process can drop whole blood degree, viscosity of blood, platelet adhesion reaction and platelet can be dropped Aggregation, it is generally used for first course for the treatment of, twice on the one, decoction sooner or later.
As preferred embodiment, described formula constituent is measured as follows in gram: Semen Coicis 10g, Rhizoma Smilacis Glabrae 10g, Herba Plantaginis 5g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 10g, Poria 5g, the Radix Astragali 5 G, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Os Gallus domesticus Grass 10g, Caulis Spatholobi 20g, Caulis Lonicerae 10g, Radix Tripterygii Wilfordii 3g, Herba speranskiae tuberculatae 5g, Rhizoma Zingiberis Recens Yellow 5g, Fructus Zanthoxyli 5g, river Radix Achyranthis Bidentatae 5g, Olibanum 1g, Myrrha 5g, Flos Carthami 1g, Caulis Sinomenii 5g, Radix Notoginseng 5g, Lignum Sappan 5g and Radix Achyranthis Bidentatae 5g；Its primary efficacy is by promoting uric acid Excretion, reduces uric acid, and；It is generally used for second course for the treatment of, twice on the one, decoction sooner or later.
As preferred embodiment, described formula constituent is measured as follows in gram: Semen Coicis 20 G, Rhizoma Smilacis Glabrae 20g, Herba Plantaginis 10g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 20g, Poria 5g, Huang Stilbene 5g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 5g, Caulis Spatholobi 5g, Caulis Lonicerae 5g, Radix Tripterygii Wilfordii 1g, Herba speranskiae tuberculatae 5g, Rhizoma Zingiberis Recens Yellow 5g, Fructus Zanthoxyli 5g, river Radix Achyranthis Bidentatae 5g, Olibanum 1g, Myrrha 5g, Flos Carthami 1g, Caulis Sinomenii 5g, Radix Notoginseng 5g, Lignum Sappan 5g and Radix Achyranthis Bidentatae 5g；Its primary efficacy is to promote urate excretion, Reduce uric acid, simultaneously can carry out the kidney invigorating and replenish the calcium, health invigorating and to joint extra-nutrition, Avoid recurrence；It is generally used for last course for the treatment of, twice on the one, decoction sooner or later.
The present invention compared with prior art, ache formula, and it can by the treatment joint of the present invention Complete a process taken stopgap measures and effect a permanent cure, treat for source of disease, therapeutic process can drop Viscosity of blood, platelet adhesion reaction and Platelet, promoting blood circulation and stopping pain, can drop in whole blood degree； By promoting urate excretion, reduce uric acid, in conjunction with dredging grain, it is possible to make to dredge at joint, Mend with unifier；Simultaneously can carry out the kidney invigorating and replenish the calcium, health invigorating and to joint extra-nutrition, Avoid the possibility of recurrence.
Detailed description of the invention
The treatment joint of the present invention is ached formula, and described formula constituent is measured as follows in gram: Semen Coicis Core 5～20g, Rhizoma Smilacis Glabrae 5～20g, Herba Plantaginis 5～10g, Radix Et Rhizoma Rhei 1～10g, Rhizoma Atractylodis 5～20 G, Poria 5～10g, the Radix Astragali 5～10g, Fructus Schisandrae Chinensis 5～10g, Radix Codonopsis 1～5g, pearl white 1～5g, Os Caprae seu Ovis 5～20g, Medulla Bovis seu Bubali 5～20g, Herba Abri 5～10g, Caulis Spatholobi 5～20g, Caulis Lonicerae 5～10g, Radix Tripterygii Wilfordii 1～3g, Herba speranskiae tuberculatae 5～10g, Rhizoma Curcumae Longae 5～10g, Fructus Zanthoxyli 5～10g, river Radix Achyranthis Bidentatae 1～5g, Olibanum 1～5g, Myrrha 5～10g, Flos Carthami 1～5g, bluish glaucoma Rattan 5～10g, Radix Notoginseng 5～10g, Lignum Sappan 5～10g and Radix Achyranthis Bidentatae 5～20g, it can be complete Become a process taken stopgap measures and effect a permanent cure, treat for source of disease, therapeutic process can drop complete Viscosity of blood, platelet adhesion reaction and Platelet, promoting blood circulation and stopping pain, can drop in blood degree； By promoting urate excretion, reduce uric acid, in conjunction with dredging grain, it is possible to make to dredge at joint, Mend with unifier；Simultaneously can carry out the kidney invigorating and replenish the calcium, health invigorating and to joint extra-nutrition, Avoid recurrence.
Embodiment 1:
Described formula constituent is measured as follows in gram: Semen Coicis 10g, Rhizoma Smilacis Glabrae 10g, Herba Plantaginis Grass 5g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 10g, Poria 5g, Radix Astragali 5g, Fructus Schisandrae Chinensis 5g, party Ginseng 1g, pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 5g, Caulis Spatholobi 5g, Caulis Lonicerae 5g, Radix Tripterygii Wilfordii 1g, Herba speranskiae tuberculatae 10g, Rhizoma Curcumae Longae 10g, Fructus Zanthoxyli 10g, river Radix Achyranthis Bidentatae 5g, Olibanum 5g, Myrrha 10g, Flos Carthami 5g, Caulis Sinomenii 10g, Radix Notoginseng 10g, Lignum Sappan 10g and Radix Achyranthis Bidentatae 20g, its primary efficacy promoting blood circulation and stopping pain, can drop in therapeutic process Viscosity of blood, platelet adhesion reaction and Platelet, can drop in whole blood degree, and it is typically used First course for the treatment of, twice on the one, decoction sooner or later.
Embodiment 2:
Described formula constituent is measured as follows in gram: Semen Coicis 10g, Rhizoma Smilacis Glabrae 10g, Herba Plantaginis Grass 5g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 10g, Poria 5g, Radix Astragali 5g, Fructus Schisandrae Chinensis 5g, party Ginseng 1g, pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 10g, Caulis Spatholobi 20 G, Caulis Lonicerae 10g, Radix Tripterygii Wilfordii 3g, Herba speranskiae tuberculatae 5g, Rhizoma Curcumae Longae 5g, Fructus Zanthoxyli 5g, river cattle Teng 5g, Olibanum 1g, Myrrha 5g, Flos Carthami 1g, Caulis Sinomenii 5g, Radix Notoginseng 5g, Lignum Sappan 5g and Radix Achyranthis Bidentatae 5g；Its primary efficacy is by promoting urate excretion, reduces uric acid, and； It is generally used for second course for the treatment of, twice on the one, decoction sooner or later.
Embodiment 3:
Described formula constituent is measured as follows in gram: Semen Coicis 20g, Rhizoma Smilacis Glabrae 20g, Herba Plantaginis Grass 10g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 20g, Poria 5g, Radix Astragali 5g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 5g, Caulis Spatholobi 5g, Caulis Lonicerae 5g, Radix Tripterygii Wilfordii 1g, Herba speranskiae tuberculatae 5g, Rhizoma Curcumae Longae 5g, Fructus Zanthoxyli 5g, river Radix Achyranthis Bidentatae 5g, Olibanum 1g, Myrrha 5g, Flos Carthami 1g, Caulis Sinomenii 5g, Radix Notoginseng 5g, Soviet Union Wood 5g and Radix Achyranthis Bidentatae 5g；Its primary efficacy is to promote urate excretion, reduces uric acid, simultaneously The kidney invigorating can be carried out and replenish the calcium, health invigorating and to joint supplement the nutrients, it is to avoid recurrence；One As for last course for the treatment of, twice on the one, decoction sooner or later.
In sum, the treatment joint of the present invention is ached formula, its can complete one take stopgap measures and The process effected a permanent cure, treats for source of disease, can drop whole blood degree, can drop blood in therapeutic process Liquid viscosity, platelet adhesion reaction and Platelet, promoting blood circulation and stopping pain；By promoting uric acid Excretion, reduces uric acid, in conjunction with dredging grain, it is possible to makes to dredge at joint, mends with unifier；With Time can carry out the kidney invigorating and replenish the calcium, health invigorating and to joint supplement the nutrients, it is to avoid recurrence can Energy.
With the above-mentioned desirable embodiment according to the present invention for enlightenment, by above-mentioned description, Relevant staff can carry out many completely in the range of without departing from this invention technological thought The change of sample and amendment.It is interior that the technical scope of this invention is not limited in description Hold, it is necessary to determine its technical scope according to right.

Claims (4)

1. a treatment joint is ached formula, it is characterised in that: described formula constituent is in gram Measure as follows: Semen Coicis 5～20g, Rhizoma Smilacis Glabrae 5～20g, Herba Plantaginis 5～10g, Radix Et Rhizoma Rhei 1～10 G, Rhizoma Atractylodis 5～20g, Poria 5～10g, the Radix Astragali 5～10g, Fructus Schisandrae Chinensis 5～10g, Radix Codonopsis 1～5g, pearl white 1～5g, Os Caprae seu Ovis 5～20g, Medulla Bovis seu Bubali 5～20g, Herba Abri 5～10g, Caulis Spatholobi 5～20g, Caulis Lonicerae 5～10g, Radix Tripterygii Wilfordii 1～3g, Herba speranskiae tuberculatae 5～10g, Rhizoma Zingiberis Recens Yellow 5～10g, Fructus Zanthoxyli 5～10g, river Radix Achyranthis Bidentatae 1～5g, Olibanum 1～5g, Myrrha 5～10g, Flos Carthami 1～5g, Caulis Sinomenii 5～10g, Radix Notoginseng 5～10g, Lignum Sappan 5～10g and Radix Achyranthis Bidentatae 5～20 g。
Treatment joint the most according to claim 1 is ached formula, it is characterised in that: described Formula constituent is measured as follows in gram: Semen Coicis 10g, Rhizoma Smilacis Glabrae 10g, Herba Plantaginis 5g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 10g, Poria 5g, Radix Astragali 5g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, Pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 5g, Caulis Spatholobi 5g, Radix Ophiopogonis Rattan 5g, Radix Tripterygii Wilfordii 1g, Herba speranskiae tuberculatae 10g, Rhizoma Curcumae Longae 10g, Fructus Zanthoxyli 10g, river Radix Achyranthis Bidentatae 5 G, Olibanum 5g, Myrrha 10g, Flos Carthami 5g, Caulis Sinomenii 10g, Radix Notoginseng 10g, Lignum Sappan 10g and Radix Achyranthis Bidentatae 20g.
Treatment joint the most according to claim 1 is ached formula, it is characterised in that: institute State formula constituent and measure as follows in gram: Semen Coicis 10g, Rhizoma Smilacis Glabrae 10g, Herba Plantaginis 5g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 10g, Poria 5g, Radix Astragali 5g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, Pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 10g, Caulis Spatholobi 20g, bear Caulis Lonicerae 10g, Radix Tripterygii Wilfordii 3g, Herba speranskiae tuberculatae 5g, Rhizoma Curcumae Longae 5g, Fructus Zanthoxyli 5g, river Radix Achyranthis Bidentatae 5g, Olibanum 1g, Myrrha 5g, Flos Carthami 1g, Caulis Sinomenii 5g, Radix Notoginseng 5g, Lignum Sappan 5g and bosom Radix Achyranthis Bidentatae 5g.
Treatment joint the most according to claim 1 is ached formula, it is characterised in that: institute State formula constituent and measure as follows in gram: Semen Coicis 20g, Rhizoma Smilacis Glabrae 20g, Herba Plantaginis 10g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 20g, Poria 5g, Radix Astragali 5g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 1g, Pearl white 1g, Os Caprae seu Ovis 5g, Medulla Bovis seu Bubali 5g, Herba Abri 5g, Caulis Spatholobi 5g, Radix Ophiopogonis Rattan 5g, Radix Tripterygii Wilfordii 1g, Herba speranskiae tuberculatae 5g, Rhizoma Curcumae Longae 5g, Fructus Zanthoxyli 5g, river Radix Achyranthis Bidentatae 5g, Olibanum 1g, Myrrha 5g, Flos Carthami 1g, Caulis Sinomenii 5g, Radix Notoginseng 5g, Lignum Sappan 5g and bosom Radix Achyranthis Bidentatae 5g.
CN201610452732.3A 2016-06-21 2016-06-21 Formulation for treating osteocomma aches Withdrawn CN105999066A (en)

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张国恩等: "痹康饮合剂急性毒性实验研究 ", 《中成药》 *

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