CN105998875A - Chinese medicinal lozenge for treatment of stomatitis and preparation method - Google Patents

Chinese medicinal lozenge for treatment of stomatitis and preparation method Download PDF

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CN105998875A
CN105998875A CN201610624906.XA CN201610624906A CN105998875A CN 105998875 A CN105998875 A CN 105998875A CN 201610624906 A CN201610624906 A CN 201610624906A CN 105998875 A CN105998875 A CN 105998875A
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herba
traditional chinese
chinese medicine
lindl
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范翠娥
郭怡芳
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Abstract

Belonging to the field of traditional Chinese medicine, the invention discloses a Chinese medicinal lozenge for treatment of stomatitis and a preparation method. The raw materials of the Chinese medicinal lozenge effective components include: Herb of Malay Blumea, Arthraxon hispidus, forrest silkvine stem or root, Cymbium melo, roughhaired holly root, Semen Sinapis, lonicera japonica, Piper sarmentosum, dendrobium lindleyi stendel, Bergia ammannioides Roxb, Bulbophyllum Inconspicuum Maxim, Nervilia fordii, laver, sedum, Polygala japonica, and Cephalanthera falcate. The Chinese medicinal lozenge provided by the invention has appropriate compatibility of medicinal materials, is accord with traditional Chinese and modern medicine and pharmacology theories, has the efficacy of clearing away heat and toxic materials, killing bacteria and diminishing swelling, removing blood stasis and relieving pain, has significant treatment effect on recurrent oral ulceration, recurrent aphthae, children herpangina, cheilitis, angular cheilitis, glossitis and other oral inflammation, and has the advantages of short course of treatment, quick effect, no recurrence after cure, safety, no toxic or side effect, normal work and life during medication, treatment of both symptoms and root causes, miraculous effect and practicability, and is worthy of wide popularization and application.

Description

A kind of Traditional Chinese medicine lozenge treating stomatitis and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Traditional Chinese medicine lozenge treating stomatitis and preparation method.
Background technology
Stomatitis is the inflammation of oral mucosa, can involve cheek mucosa, tongue, gums, palate etc..It is more common for period children's, Especially infant, can fall ill merely and also can be secondary to the systemic diseases such as diarrhoea, malnutrition, actute infection, eipathia asthenia Time.Cause stomatitis mainly has antibacterial, virus and fungus.Bacterial infection stomatitis often causes with streptococcus and staphylococcus for main Pathogenic bacteria.These antibacterials are under the low situation of the Abwehrkraft des Koepers such as actute infection, long-term diarrhea, if oral cavity is unclean, then cause antibacterial big Amount breeding, thus cause Acute oral mucosa injury.
In oral cavity, each position all can occur stomatocace, in being common in lip, tongue and cheek mucosa etc., can spread to lip and Bottleneck throat.From the beginning of mucosa hyperemia, edema, can have herpes, the erosion differed in size afterwards or ulcer, wound surface covers thicker fibre The canescence of dimension disposition exudate formation or yellow pseudomembrane, clear border, it is easy to wipe, leave over the rotten to the corn face of hemorrhage after wiping, no For a long time pseudomembrane occurs again.Local pain, lymphadenectasis.Refusing to eat, agitation, heating 39 DEG C～40 DEG C.General Symptoms the lighter one Week, left and right temperature recovery was normal, and ulcer is gradually fully recovered；Severe one may occur in which dehydration and acidosis.
During herpetic stomatitis onset, heating reaches 38 DEG C～40 DEG C, after 1～2 day, in gums, lip, each position such as tongue, cheek mucosa There is the single or exanthema vesiculosum of cluster, diameter 2～3mm in oral mucosa, around has blush, forms ulcer, have Huang after rapid ulceration White fiber disposition secretions covers, and multiple ulcer can be fused into irregular big ulcer, sometimes involves palate and pharyngeal.At mouth The most often there is skin ulcer herpes in angle and lip week skin, pain quite play, refusing to eat, sialorrhea, agitation, the frequent enlargement of submandibular lymph nodes.Body temperature is 3 ～recover normal after 5 days, the course of disease 1～2 weeks.Sustainable 2～3 weeks of regional glandular enlargement.Primary disease should reflect with herpangina Not, the latter is caused by Coxsackie virus, multiple is born in summer and autumn, and skin ulcer rash occurs mainly in pharyngeal and soft palate, sometimes see tongue but Do not involve gums and cheek mucosa, submandibular lymph nodes enlargement.
Drug sensitivity stomatitis be taken certain medicine after, make oral mucosa generation acute inflammation show.Typically taking medicine Morbidity in latter about 24 hours.Its early symptom is that oral mucosa is congested, edema or erythema and vesicle etc. occur.Owing to medicine is continuous Absorb, make early symptom gradually increase the weight of and form mucosa to fester.This mucosa face of festering is different from the performance of general aphtha, bursts at it Rotten the courageous and upright secretions of upper covering, ulceration swelling, usually cause zest to have an intense pain, child is refusing to eat because of pain.
Candidiasis angular cheilitis be feature be often to suffer from for bilateral, the skin in bicker district is chapped with mucosa, neighbouring skin Skin is congested with mucosa, and often there are erosion and exudate in the place of chapping, or have thin crust, pain or hemorrhage when dehiscing.This kind is with wet white gruel The rotten mycotic angular cheilitis being characterized, should distinguish with hypovitaminosis B2 or antibacterial angular cheilitis, the former simultaneously and concurrently glossitis, lip Inflammation, scrotitis or vulvitis, the many single-shots of the latter are in side bicker, positive bacterial culture (based on streptococcus)；And candidiasis mouth Angle inflammation is multiple is born in child, health decaying patient and inpatient with haematological diseases.The angular cheilitis of older patients is many to contract with preferred vertical dimension of occlusion Short relevant, bicker district skin subsides in channel form, causes saliva to be overflowed in ditch by bicker, therefore often in dampness, favorably Breed in fungus growth.
The Chinese medicine and western medicine for the treatment of stomatitis is various in style at present, and the big multi-component complex of western medicine, therapeutic domain is narrow, takes for a long time Big with side effect, not only therapeutic effect difference and also bring to the health of patient and greatly injure.
Summary of the invention
The invention provides a kind of Traditional Chinese medicine lozenge treating stomatitis and preparation method；Medical material selected by Traditional Chinese medicine lozenge of the present invention Compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has heat-clearing and toxic substances removing, sterilization detumescence, effect of stasis-dispelling and pain-killing, To oral inflammation tools such as treatment recurrent oral ulceration, recurrent aphtha, children's's Herpangina, cheilitis, angular cheilitis, glossitis There are significant curative effect, short treating period, instant effect, non-relapse after healing, safe without toxic side effect, can normally work and give birth to during medication Living, treating both the principal and secondary aspects of a disease, special effect is practical, and should be widely promoted application.
For achieving the above object, technical scheme is implemented as follows:
A kind of Traditional Chinese medicine lozenge treating stomatitis, makes raw material composition and the parts by weight of described Traditional Chinese medicine lozenge effective ingredient For:
Make described Traditional Chinese medicine lozenge effective ingredient raw material composition and parts by weight be:
Make described Traditional Chinese medicine lozenge effective ingredient raw material composition and parts by weight be:
Make described Traditional Chinese medicine lozenge effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Traditional Chinese medicine lozenge treating stomatitis, comprises the following steps that:
(1) Herba Blumeae Lacerae, Herba Arthraxonis Hispidi, Cymbium melo (sdander), Radix Ilicis Asprellae, Semen Sinapis, vacation, Dendrobium jenkinsii Wall ex Lindl．, close flowers and plants, Thallus Porphyrae and Cephalanthera falcata (Thunb) Lindl are cleaned, Put into container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～ 8 times amount distilled water, boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract； Merging three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) Caulis et Radix Periplocae Forrestii, Flos Lonicerae, Herba Bulbophylli inconspicui and Folium Nerviliae fordii are cleaned, immerse 4 times amount 70% alcohol solution dipping 1～2 Hour, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, concentration be at 65 DEG C relative density be 1.12～1.16 thick Cream, standby；
(3) Herba hylotelephii erythrosticti is cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(4) Herba Polygalae Japonicae is put into container, carry out pulverization process, grind into powder, obtain the fine powder of 180 mesh, standby；
(5) thick paste, juice and the fine powder obtained by above-mentioned steps (1)～(4) is made tablet, obtain described treatment The Traditional Chinese medicine lozenge of stomatitis.
The property of medicine of Chinese medicine used by the present invention is as follows:
Herba Blumeae Lacerae: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For tonsillitis, stomatitis, gingival abscess is popular Property parotitis, infantile pneumonia；Ulcerative carbuncle toxic swelling, skin pruritus are controlled in external." Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, antiinflammatory.Control little Youngster's pneumonia, tonsillitis, parotitis, stomatitis, innominate toxic swelling, skin pruritus.”
Herba Arthraxonis Hispidi: bitter in the mouth, property is put down.Heat clearing away, sending down the abnormal ascending QI, relieving cough and asthma, removing toxic substances, rheumatism.Curing mainly hepatitis, chronic cough is panted, throat Inflammation, stomatitis, rhinitis, lymphadenitis, mastitis, control scabies, skin pruritus, carbuncle furuncle." property of medicine opinion " carries: " control all malignant boil.”
Caulis et Radix Periplocae Forrestii: sweet in the mouth, pungent, warm in nature.The meridian dredging, wind-damp dispelling, anti inflammatory blood quickening.Control traumatic injury, rheumatic arthritis, menstruation Uncomfortable, stomatitis, mastitis." Kunming conventional medical herbs among the people " carries: " wind-damp dispelling, the meridian dredging, eliminating inflammation and expelling toxin.Dispelling the wind and dampness pathogens traumatic injury aches Bitterly, hot sore, mastitis, pharyngolaryngitis, stomatitis.”
Cymbium melo (sdander): acrid in the mouth, sweet, property is put down；Enter lung, stomach two warp.Relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, hold back acid pain relieving.For anemopyretic cold, heating, head Bitterly, cough, thirsty, gastric heat pantothenic acid, the middle part of gastric cavity have burn feeling, xerostomia to be intended to cool drink, notably severe pain.
Radix Ilicis Asprellae: bitter in the mouth, sweet, cold in nature；Return lung, liver, large intestine channel.Heat clearing away, promotes the production of body fluid, dissipating blood stasis, removing toxic substances.Main flu, headache, dizzy Dizzy, calentura excessive thirst, eruptive disease, diarrhea of heat type, lung abscess, pertussis, laryngopharynx swelling and pain, hemorrhoidal bleeding, gonorrhea, furuncle swelling toxin, traumatic injury." Nanning City's medicine will " carry: " heat-clearing and toxic substances removing, lung moistening is quenched the thirst.Soothe sore throat thirsty, hemoptysis, eruptive disease.”
Semen Sinapis: acrid in the mouth, warm in nature, return lung meridian.Warming spleen and stomach for dispelling cold, promoting the circulation of QI eliminating phlegm, the meridian dredging, detumescence poison.Control cold syndrome of the stomach and tell food, trusted subordinate Pain, lung cold cough, arthralgia aggravated by cold, sore throat, carbuncle of yin nature, the tuberculosis of bone and joint, traumatic injury." detailed outline " carries: " warming spleen and stomach for dispelling cold, eliminating phlegm profit key.Control cold syndrome of the stomach Tell food, lung cold cough, air-cooled pain due to disorder of QI, locked mouth lockjaw.Dissipation carbuncle, blood stasis.”
Flos Lonicerae: sweet in the mouth, micro-hardship, cold in nature；Return lung, stomach, the heart, large intestine channel.Heat clearing away is eliminating evil, dispelling wind-heat, removing summer-heat blood poison.Existing Showing for pharmacological research, the effective ingredient in Flos Lonicerae has antibacterial and antivirus action, to staphylococcus aureus, hemolytic Streptococcus, dysentery bacterium, Bacillus typhi, meningococcus, Diplococcus pneumoniae, bacillus pyocyaneus and influenza virus etc. have bright Aobvious inhibitory action, and immunologic function can be strengthened, antiinflammatory, antipyretic, inflammation there is is obvious inhibiting effect.
False: bitter in the mouth, warm in nature；GUIXIN, lung, spleen, large intestine channel.Expelling wind and cold, promoting the circulation of QI to relieve pain, active, detumescence.Main air is cold to be coughed Breathe heavily, rheumatic arthralgia, distension and fullness in the abdomen, dysentery, puerperal swelling of the feet, traumatic injury." the SHENGCAO property of medicine standby will " carries: " controls toothache, washes rotten Foot.”
Dendrobium jenkinsii Wall ex Lindl．: sweet in the mouth, light, cool in nature；Attach to the lung and stomach meridians.Nourishing the lung to arrest cough, tonifying-Yin and nourishing-stomach.Cure mainly cough due to lung-heat, pulmonary tuberculosis, Asthma, dysentery, stomatitis, stomachache, infant malnutrition.
Close flowers and plants: sweet in the mouth, cool in nature.Heat-clearing and toxic substances removing.Main urinary tract infection, carbuncle furuncle, stomatitis.
Herba Bulbophylli inconspicui: sweet in the mouth, light, cool in nature；Enter lung, stomach two warp.Nourishing YIN and clearing away heat, preventing phlegm from forming and stopping coughing.For xeropulmonary cough, pulmonary tuberculosis is coughed up Blood, calentura excessive thirst, tonsillitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " moistening the lung and resolving phlegm, tonifying-Yin and nourishing-stomach.Control pulmonary tuberculosis to cough Cough, spitting of blood, cough due to chronic tracheitis, pneumonia convalescent period, chronic pharyngalgia, chronic gastritis, achlorhydria, inappetence, seminal emission.”
Folium Nerviliae fordii: bitter in the mouth, sweet, property is put down.Clearing away lung-heat to relieve cough, spleen invigorating removing food stagnancy, sedation-analgesia, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, it is used for Pulmonary tuberculosis cough spitting of blood, bronchitis, infantile malnutrition, infantile pneumonia, psychosis, treating swelling and pain by traumatic injury, stomatitis, acute laryngitis, Sore." Nanning City's medicine will " carries: " nourishing the lung to arrest cough antipyretic clears away heart-fire.Control pulmonary tuberculosis, and solve carbon monoxide poisoning.”
Thallus Porphyrae: sweet in the mouth, salty, cold in nature；Return lung, spleen, bladder warp.Resolving phlegm and softening hard masses, smooth throat to stop cough, relieving restlessness of nourishing heart, diuretic dehumidifies. Main goiter, tinea pedis, edema, laryngopharynx swelling and pain, cough, irritated insomnia, urine leaching pain, dysentery." with earnestly occupying diet spectrum " carries: " and blood Nourishing heart, be tired of clearly and wash heat, control and be insomnia, throat, except tinea pedis goiter, row dysentery time main, analysis is waken up and is whetted the appetite.”
Herba hylotelephii erythrosticti: sour in the mouth, hardship, property is put down.Expelling wind and removing dampness, promoting blood circulation to remove blood stasis, hemostasis and pain-relieving.For laryngitis, urticaria, spit blood, little Youngster's erysipelas；Furuncle carbuncle, traumatic injury, clavus, burn and scald, venom, herpes zoster, tinea pedis are controlled in external.
Herba Polygalae Japonicae: taste is micro-pungent, slightly warm in nature.Promoting blood circulation to remove blood stasis, eliminating phlegm and relieving cough, pain relieving of detoxifying.For pharyngitis, tonsillitis, mouth Chamber is scorching, and cough, infantile pneumonia, infantile malnutrition, urinary system calculus, mastitis, osteomyelitis, venom, furuncle furuncle and phyma are controlled in external. " illustrated handbook planted by middle traditional Chinese medicines " carries: " root is calm, expectorant, and energy intelligent promoting and the mind tranquilizing dissipates strongly fragrant reducing phlegm, and disappears red swollen.Control bronchitis, pneumonia, Cough ant phlegm, palpitation with fear, forgetful carbuncle skin ulcer swells, sore throat.”
Cephalanthera falcata (Thunb) Lindl: sweet in the mouth, cold in nature；Return Liver Channel.Heat clearing away, pathogenic fire purging, removing toxic substances.Cure mainly laryngopharynx swelling and pain, toothache, venom." Xinhua Book on Chinese herbal medicine outline " carry: " herb, has heat clearing away, the function of pathogenic fire purging.For having sore throat, having a toothache.
The present invention compared with prior art, has the advantages that
1, Traditional Chinese medicine lozenge of the present invention is to treatment recurrent oral ulceration, recurrent aphtha, children's's Herpangina, lip The oral inflammations such as inflammation, angular cheilitis, glossitis have significant curative effect, short treating period, instant effect, non-relapse after healing, and safety non-toxic is secondary Effect.
2, medical material compatibility selected by Traditional Chinese medicine lozenge of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has Heat-clearing and toxic substances removing, sterilization detumescence, effect of stasis-dispelling and pain-killing, can normally work and live during medication, treating both the principal and secondary aspects of a disease, and special effect is practical, Should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Traditional Chinese medicine lozenge effective ingredient of the present invention forms and weight is:
The preparation method of a kind of Traditional Chinese medicine lozenge treating stomatitis, comprises the following steps that:
(1) Herba Blumeae Lacerae, Herba Arthraxonis Hispidi, Cymbium melo (sdander), Radix Ilicis Asprellae, Semen Sinapis, vacation, Dendrobium jenkinsii Wall ex Lindl．, close flowers and plants, Thallus Porphyrae and Cephalanthera falcata (Thunb) Lindl are cleaned, Put into container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～ 8 times amount distilled water, boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract； Merging three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) Caulis et Radix Periplocae Forrestii, Flos Lonicerae, Herba Bulbophylli inconspicui and Folium Nerviliae fordii are cleaned, immerse 4 times amount 70% alcohol solution dipping 1～2 Hour, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, concentration be at 65 DEG C relative density be 1.12～1.16 thick Cream, standby；
(3) Herba hylotelephii erythrosticti is cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(4) Herba Polygalae Japonicae is put into container, carry out pulverization process, grind into powder, obtain the fine powder of 180 mesh, standby；
(5) thick paste, juice and the fine powder obtained by above-mentioned steps (1)～(4) is made tablet, obtain described treatment The Traditional Chinese medicine lozenge of stomatitis.
Usage and dosage: buccal or oral all can, every day 2 times, the most each 1 time, each 1 (every 0.5g), buccal after meal Or warm water delivery service；Within 5 days, being 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of Traditional Chinese medicine lozenge effective ingredient of the present invention forms and weight is:
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Traditional Chinese medicine lozenge effective ingredient of the present invention forms and weight is:
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Traditional Chinese medicine lozenge effective ingredient of the present invention forms and weight is:
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 5
The raw material of Traditional Chinese medicine lozenge effective ingredient of the present invention forms and weight is:
The Traditional Chinese medicine lozenge preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
As the Traditional Chinese medicine lozenge for the treatment of stomatitis, selecting the stomatitis patient 450 example clinical observation made a definite diagnosis, patient divides at random Become treatment group and matched group two groups, treatment group 225 example, wherein male 112 example, women 113 example, age 10～67 years old, average year 38.5 years old age, average course of disease half a year；Matched group 225 example, wherein male 113 example, women 112 example, age 11～68 years old, average year 39.5 years old age, average course of disease half a year.
Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparable Property.
2, medicament selection:
Treatment group takes Traditional Chinese medicine lozenge of the present invention, buccal or oral all can, every day 2 times, the most each 1 time, each 1 is (every Sheet 0.5g), buccal or warm water delivery service after meal；Within 5 days, being 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, the person of being in a bad way follows the doctor's advice The meal with wine amount of adding.
Matched group takes his capsule four-dimensional, oral, 3 times on the one, and adult one time 1, children's is cut down according to the circumstance, and takes 1/3～1/2 Grain, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: recurrent oral ulceration, recurrent aphtha, children's's Herpangina, cheilitis, angular cheilitis, glossitis etc. Stomatitis symptom all disappears, and gets well in oral cavity.
(2) effective: above-mentioned symptom substantially alleviates, oral cavity is clearly better.
(3) effective: above-mentioned symptom has alleviated, and oral cavity has taken a turn for the better.
(4) invalid: by above-mentioned symptom after treatment without alleviating or increasing the weight of.
4, result:
Select in the treatment group of Traditional Chinese medicine lozenge of the present invention, cure 137 examples, effective 54 examples, effective 31 examples, invalid 3 examples, cure Rate 60.9%, total effective rate 98.7%.
Matched group is cured 118 examples, effective 48 examples, effective 29 examples, invalid 30 examples, cure rate 52.4%, total effective rate 86.7%.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Zheng, female, 15 years old, people from Hegang, Heilungkiang.Suffering from more than stomatitis half a year, gingiva is the most hemorrhage, stings thing unable, Odontoseisis before lower, occasionally has dental bed swelling, suppurates, introduce through friend to our hospital, takes Traditional Chinese medicine lozenge of the present invention treatment, takes After 1 course for the treatment of, dental bed swelling, transference cure of suppurating, gingival hemorrhage phenomenon is obviously improved, and after taking 2 courses for the treatment of, above-mentioned symptom is thorough The end, disappears, and follows up a case by regular visits to not recur so far.
2, desolate certain, man, 20 years old, people from Beijing Xicheng District.Patient's oral cavity pain can not be taken food, oral mucosa or the tip of the tongue, lingual surface The ulcer surface of size as visible several pieces of Semen Sesamis, oral secretion plate coating checking candidiasis is positive, is diagnosed as the microbial mouth of beads Chamber ulcer, takes Traditional Chinese medicine lozenge of the present invention treatment, and after taking 1 course for the treatment of, symptom substantially alleviates, after continuing to take 2 courses for the treatment of, and disease Shape all disappears, and follows up a case by regular visits to without recurrence after 1 year
3, Zeng, man, 31 years old, Huainan, Anhui people.Patient suffers from oral inflammation, uses several method to treat, and effect is not Good, rear to our hospital, take Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, symptom has alleviated, and continues clothes After 2 courses for the treatment of, symptom all disappears, and follows up a case by regular visits to without recurrence after 1 year.
4, journey, female, 40 years old, Quanzhou, Fujian people.Patient's oral cancer is postoperative, occasionally has pain, soft food difficulty of taking food, and looks into Body oral mucosa congestion and edema, has a small amount of exudate, and through western medicines in treatment, effect is general, takes Traditional Chinese medicine lozenge of the present invention treatment, After taking 1 course for the treatment of, symptom is substantially alleviated, and after taking 2 courses for the treatment of, symptom all disappears, recovery from illness, follows up a case by regular visits to without recurrence after half a year.
5, Yuan, man, 28 years old, people from Wansheng District, Chongqing.Patient suffers from the stomatitis symptom such as cheilitis, glossitis, and winter more so, takes With crossing multiple Drug therapy, have no improvement, the most to our hospital, take Traditional Chinese medicine lozenge of the present invention treatment, take 1 treatment Cheng Hou, symptom substantially alleviates, and after continuing to take 1 course for the treatment of, symptom all disappears, and after half a year, Effect of follow-up visit by telephone is without recurrence.
6, Shen, female, 52 years old, Guangdong Huizhou people.Respectively there is aphtha more than 1 year on the right side of buccal, patient oral cavity and the both sides of tongue. Examining and see dysphoria and insomnia, complexion is sent out red, self-induction palpitating speed, bitter taste lack of appetite, constipation with dry stool, red tongue, and yellow fur is thick, just comes my institute Examining, take Traditional Chinese medicine lozenge of the present invention treatment, after taking 1 course for the treatment of, oral ulcer slightly takes a turn for the better, and takes 3 courses for the treatment of, oral ulcer All disappear, recovery from illness, follow up a case by regular visits to not recur so far.

Claims (5)

1. the Traditional Chinese medicine lozenge treating stomatitis, it is characterised in that: make the raw material composition of described Traditional Chinese medicine lozenge effective ingredient And parts by weight are:
Herba Blumeae Lacerae 37～61 parts of Herba Arthraxonis Hispidis 37～61 parts of Caulis et Radix Periplocae Forrestiis 36～60 parts of Cymbium melo (sdander) 36～60 parts
Radix Ilicis Asprellae 34～58 parts of Semen Sinapiss 32～32～56 parts of vacations of 56 portions of Flos Loniceraes 31～55 parts
Dendrobium jenkinsii Wall ex Lindl． 30～54 parts of close flowers and plants 30～54 parts of Herba Bulbophylli inconspicui 27～51 parts of Folium Nerviliae fordiis 26～50 parts
Thallus Porphyrae 26～50 parts of Herba hylotelephii erythrostictis 25～47 parts of Herba Polygalae Japonicae 24～42 parts of Cephalanthera falcata (Thunb) Lindl 22～39 parts.
A kind of Traditional Chinese medicine lozenge treating stomatitis the most according to claim 1, it is characterised in that: make described Traditional Chinese medicine lozenge The raw material of effective ingredient forms and parts by weight are:
Herba Blumeae Lacerae 41～57 parts of Herba Arthraxonis Hispidis 41～57 parts of Caulis et Radix Periplocae Forrestiis 40～56 parts of Cymbium melo (sdander) 40～56 parts
Radix Ilicis Asprellae 38～54 parts of Semen Sinapiss 36～36～52 parts of vacations of 52 portions of Flos Loniceraes 35～51 parts
Dendrobium jenkinsii Wall ex Lindl． 34～50 parts of close flowers and plants 34～50 parts of Herba Bulbophylli inconspicui 31～47 parts of Folium Nerviliae fordiis 30～46 parts
Thallus Porphyrae 30～46 parts of Herba hylotelephii erythrostictis 29～43 parts of Herba Polygalae Japonicae 27～39 parts of Cephalanthera falcata (Thunb) Lindl 25～37 parts.
A kind of Traditional Chinese medicine lozenge treating stomatitis the most according to claim 1, it is characterised in that: make described Traditional Chinese medicine lozenge The raw material of effective ingredient forms and parts by weight are:
Herba Blumeae Lacerae 45～53 parts of Herba Arthraxonis Hispidis 45～53 parts of Caulis et Radix Periplocae Forrestiis 44～52 parts of Cymbium melo (sdander) 44～52 parts
Radix Ilicis Asprellae 42～50 parts of Semen Sinapiss 40～40～48 parts of vacations of 48 portions of Flos Loniceraes 39～47 parts
Dendrobium jenkinsii Wall ex Lindl． 38～46 parts of close flowers and plants 38～46 parts of Herba Bulbophylli inconspicui 35～43 parts of Folium Nerviliae fordiis 34～42 parts
Thallus Porphyrae 34～42 parts of Herba hylotelephii erythrostictis 33～39 parts of Herba Polygalae Japonicae 30～36 parts of Cephalanthera falcata (Thunb) Lindl 28～34 parts.
A kind of Traditional Chinese medicine lozenge treating stomatitis the most according to claim 1, it is characterised in that: make described Traditional Chinese medicine lozenge The raw material of effective ingredient forms and parts by weight are:
49 parts of Herba Arthraxonis Hispidis of Herba Blumeae Lacerae, 48 parts of Cymbium melo (sdander) of 49 parts of Caulis et Radix Periplocae Forrestiis 48 parts
46 parts of Semen Sinapiss of Radix Ilicis Asprellae, 44 parts of vacations of 44 portions of Flos Loniceraes 43 parts
The close flowers and plants of Dendrobium jenkinsii Wall ex Lindl． 42 parts 39 parts of Folium Nerviliae fordiis of 42 parts of Herba Bulbophylli inconspicui 38 parts
38 parts of Herba hylotelephii erythrostictis of Thallus Porphyrae, 33 parts of Cephalanthera falcata (Thunb) Lindl of 36 parts of Herba Polygalae Japonicae 31 parts.
5. the preparation method of the Traditional Chinese medicine lozenge treating stomatitis as described in any one of Claims 1 to 4, it is characterised in that: Comprise the following steps that:
(1) Herba Blumeae Lacerae, Herba Arthraxonis Hispidi, Cymbium melo (sdander), Radix Ilicis Asprellae, Semen Sinapis, vacation, Dendrobium jenkinsii Wall ex Lindl．, close flowers and plants, Thallus Porphyrae and Cephalanthera falcata (Thunb) Lindl are cleaned, put into In container, add the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times Amount distilled water, boils 2～3 hours, extracts；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge Three extracting solution, filter, obtain filtrate, and being condensed into relative density at 60 DEG C is the thick paste of 1.10～1.13, standby；
(2) Caulis et Radix Periplocae Forrestii, Flos Lonicerae, Herba Bulbophylli inconspicui and Folium Nerviliae fordii are cleaned, immerse 4 times amount 70% alcohol solution dipping 1～2 hours, Heating extraction 3 hours, reclaims ethanol, filters, obtains filtrate, and concentration is that at 65 DEG C, relative density is the thick paste of 1.12～1.16, standby With；
(3) Herba hylotelephii erythrosticti is cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(4) Herba Polygalae Japonicae is put into container, carry out pulverization process, grind into powder, obtain the fine powder of 180 mesh, standby；
(5) thick paste, juice and the fine powder obtained by above-mentioned steps (1)～(4) is made tablet, obtain described treatment oral cavity Scorching Traditional Chinese medicine lozenge.
CN201610624906.XA 2016-07-30 2016-07-30 Chinese medicinal lozenge for treatment of stomatitis and preparation method Pending CN105998875A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102225141A (en) * 2011-06-01 2011-10-26 刘湘秋 Traditional Chinese medicine tablet for treating chronic faucitis
CN105395831A (en) * 2015-12-10 2016-03-16 杨献美 A medicine composition for treating oral inflammation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102225141A (en) * 2011-06-01 2011-10-26 刘湘秋 Traditional Chinese medicine tablet for treating chronic faucitis
CN105395831A (en) * 2015-12-10 2016-03-16 杨献美 A medicine composition for treating oral inflammation

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* Cited by examiner, † Cited by third party
Title
赵永魁: "中药"解毒丸"治疗口腔炎、牙周炎、喉炎414例", 《西南民族学院学报(自然科学版)》 *

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