CN105998728A - Traditional Chinese medicinal composition for treating diabetes as well as preparation method and application - Google Patents
Traditional Chinese medicinal composition for treating diabetes as well as preparation method and application Download PDFInfo
- Publication number
- CN105998728A CN105998728A CN201610359730.XA CN201610359730A CN105998728A CN 105998728 A CN105998728 A CN 105998728A CN 201610359730 A CN201610359730 A CN 201610359730A CN 105998728 A CN105998728 A CN 105998728A
- Authority
- CN
- China
- Prior art keywords
- parts
- diabetes
- chinese medicine
- medicine composition
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicinal composition for treating diabetes as well as a preparation method and application. The composition is prepared from the following bulk drugs in parts by weight: 495-505 parts of herba cistanches, 1990-2010 parts of fructus lycii, 595-605 parts of rhizoma polygonati, 990-1010 parts of carapax trionycis recens, 48-52 parts of dendrobium officinale kimura ex migo, 98-102 parts of American ginsengs, 48-52 parts of ginsengs, 195-205 parts of rhizoma bletillae, 4.5-5.5 parts of pericarpium zanthoxyli, 245-255 parts of semen cuscutae, 98-102 parts of pericarpium granati and 98-102 parts of radix rehmanniae preparata. The composition provided by the invention is applicable to the treatment of type-II diabetes and type-III diabetes, can gradually increase fat, a body weight and physical strength, and improves syndromes of hypodynamia, emaciation with a sallow complexion, a dull complexion, a weight loss and the like.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of treat the Chinese medicine composition of diabetes, preparation method and application.
Background technology
Diabetes are to be fallen back by immunologic function and multiple virulence factor acts on body the causes body hypoinsulinism such as diet is the most normal, thus a series of metabolism disorders such as the sugar caused, protein, fat, water and electrolyte.Its harm almost involves and whole body any tissue internal organs, may result in infection, heart change, cerebrovascular disease, renal failure, lose the sight of both eyes, lower limb gangrene etc., thus become the lethal main cause disabled.Additionally, the hypoglycemia that diabetic hyperosmolar ketoacidosis and glucose-lowering treatment cause is the serious acute complication of diabetes.The treatment of diabetes is the most unsatisfactory, the medicine of the treatment diabetes that exploitation is efficiently, low toxicity, curative effect are lasting, and to solve the problem that diabetes take medicine throughout one's life be the vital task treating diabetes.
At present, the Western medicine for the treatment of diabetes includes sulfonylurea drugs, biguanides, gliclazide class medicine and excellent must the para-insulin such as woods, Men Dong, peaceful, the sweet essence of promise.Diabetes the most still can not thoroughly be cured by these medicines, and have toxic and side effects in various degree.Hypoglycemic reaction is easily there is such as sulfonylurea drugs.The Western medicine such as metformin, gliclazide, and the heart, Liver and kidney function exhaustion, diabetic ketoacidosis, precoma stage etc. all disable.Insulin treatment easily occur hypoglycemia, serious time can be fatal, and easily cause the directly infringement such as central nervous system's regulating liver-QI, kidney, eye, also can cause three types, highly semicoma people, hepatitis, nephritis, keratitis, Os Sus domestica is fractured, Os Sus domestica has broken diabetes patient, express train aggravates one's illness deterioration, directly result in the 2nd day dead.Blood-sugar lowering tcm drug product on market about 40 kinds, therapeutic goal and the mechanism of action of most products are indefinite.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating diabetes and preparation method, it is possible to treatment II type and type III diabetes, effect is notable.
The technical scheme is that a kind of Chinese medicine composition treating diabetes, the following raw material medicaments including by weight: Herba Cistanches 495 ~ 505 parts, Fructus Lycii 1990 ~ 2010 parts, Rhizoma Polygonati 595 ~ 605 parts, raw Carapax Trionycis 990 ~ 1010 parts, Herba Dendrobii 48 ~ 52 parts, Radix Panacis Quinquefolii 98 ~ 102 parts, Korean Ginseng 48 ~ 52 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 195 ~ 205 parts, 4.5 ~ 5.5 parts of Pericarpium Zanthoxyli, Semen Cuscutae 245 ~ 255 parts, Pericarpium Granati 98 ~ 102 parts, 98 ~ 102 parts of Radix Rehmanniae Preparata.
Preferably, each raw material medicines in portions by weight is: Herba Cistanches 500 parts, Fructus Lycii 2000 parts, Rhizoma Polygonati 600 parts, raw Carapax Trionycis 1000 parts, Herba Dendrobii 50 parts, Radix Panacis Quinquefolii 100 parts, Korean Ginseng 50 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 200 parts, 5 parts of Pericarpium Zanthoxyli, Semen Cuscutae 250 parts, Pericarpium Granati 100 parts, 100 parts of Radix Rehmanniae Preparata.
Said composition dosage form is injection or oral formulations, preferably granule.
The preparation method of above-mentioned Chinese medicine composition, decocts described starting material with water, filters, filtrate is condensed into extractum, adds pharmaceutic adjuvant and is prepared from.
Preferably, decoct three times, for the first time add 8 ~ soak by water of 12 times amount 1.5 ~ 2.5 hours；Second time adds 6 ~ soak by water of 10 times amount 0.8 ~ 1.2 hour；Third time adds 5 ~ soak by water of 8 times amount 0.8 ~ 1.2 hour.
Preferably, being concentrated into 60 DEG C of relative densities is the thick paste of 1.27-1.33.
Preferably, extractum addition dextrin prepares granule.
The diseases such as the present composition is applicable to II type and type III treating diabetes, it is possible to be gradually increased fat, body weight and muscle power, improves weak all over, emaciation and sallow complexion, intensely dark and lose weight.Can promoting the circulation of blood nourish blood, blood circulation promoting and blood stasis dispelling blood, tissue regeneration promoting blood, increase vascular flow amount, improve blood vessel microcirculation.Improve and progressively alleviate angina cordis, liver pain, toothache, ophthalmalgia.After diabetes injection insulin inaction, available this product replaces treatment.
Detailed description of the invention
Following example are for being further appreciated by the essence of the present invention, but do not limit the scope of the present invention with this.
Embodiment
1
The Chinese medicine composition for the treatment of diabetes, wherein raw material composition is as follows:
Herba Cistanches 500 grams, Fructus Lycii 2000 grams, Rhizoma Polygonati 600 grams, raw 1000 grams of Carapax Trionycis shell, Herba Dendrobii 50 grams, Radix Panacis Quinquefolii 100 grams, Korean Ginseng 50 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 200 grams, 5 grams of Pericarpium Zanthoxyli, Semen Cuscutae 250 grams, Pericarpium Granati 100 grams, 100 grams of Radix Rehmanniae Preparata.
The technique preparing extractum and preparation thereof, step is as follows:
1) above-mentioned raw materials is cleaned, join and multi-function extractor decocts three times, add for the first time the soak by water 2 hours of 10 times amount (multiple of raw material gross weight), filter；Second time adds the soak by water 1 hour of 8 times amount, filters；Third time adds the soak by water 1 hour of 6 times amount, filters, merges three filtrates；
2) filtrate of upper step is passed through in two effect energy-saving concentrators concentration, to be concentrated to a certain amount of after, by filter proceed in spherical concentrator continue concentrate, be concentrated into relative density (relative water) and be 1.27-1.33(60 DEG C) thick paste time obtain extractum；
3) extractum and pharmaceutic adjuvant are mixed and made into the oral dosage form such as oral liquid, granule.Described pharmaceutic adjuvant is all that this area is conventional, and such as filler, disintegrating agent, binding agent etc., preparation method is also conventional method.
Granule uses following step to prepare: by step 2) extractum and adjuvant dextrin by the weight ratio mix and blend of 1:2, granulations, granulate, prepare granule, load and fill, prepared granule, every bag of 3g Han extractum.
Embodiment
2
The Chinese medicine composition for the treatment of diabetes, wherein raw material composition is as follows:
Herba Cistanches 495 grams, Fructus Lycii 2010 grams, Rhizoma Polygonati 595 grams, raw 990 grams of Carapax Trionycis shell, Herba Dendrobii 52 grams, Radix Panacis Quinquefolii 102 grams, Korean Ginseng 48 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 195 grams, 5.5 grams of Pericarpium Zanthoxyli, Semen Cuscutae 245 grams, Pericarpium Granati 102 grams, 98 grams of Radix Rehmanniae Preparata.
The technique preparing extractum and preparation thereof is same as in Example 1.
Embodiment
3
The Chinese medicine composition for the treatment of diabetes, wherein raw material composition is as follows:
Herba Cistanches 505 grams, Fructus Lycii 1990 grams, Rhizoma Polygonati 605 grams, raw 1010 grams of Carapax Trionycis shell, Herba Dendrobii 48 grams, Radix Panacis Quinquefolii 98 grams, Korean Ginseng 52 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 205 grams, 4.5 grams of Pericarpium Zanthoxyli, Semen Cuscutae 255 grams, Pericarpium Granati 98 grams, 102 grams of Radix Rehmanniae Preparata.
The technique preparing extractum and preparation thereof is same as in Example 1.
The invention belongs to non-toxic product, it is the highest 20 times to take 3 causes every day, 1 hour after meal or be administered once in 3 hours, oral the most, blood sugar lowering amount is the most.Blood sugar lowering is started after taking 2 minutes, medicine start to rise after 1h bounce-back (this be take this product after, drug effect starts after 2 minutes, nourish blood in promoting the circulation of blood, blood circulation promoting and blood stasis dispelling blood and tissue regeneration promoting blood and expand blood vessel, increase vascular flow amount), fasting glucose about started progressively blood sugar lowering in 2 hours in 5 hours, can decline and cause more hypoglycemia (2 months being a course for the treatment of), just start to add this medicine to halve dose in 15 days and take, about can gradually dosage after first quarter moon, the most gradually decrement after last blood glucose is normal, it is possible to start gradually decrement after two months.
Embodiment
1
Efficacy experiment
Diabetics, totally 150 examples (wherein II type 95 example, III type 55 example), the maleest 80 examples, female 70 example, minimum 15 years old of age, maximum 70 years old, fat 50 examples of build, medium 40 examples of build, build is become thin 60 examples, the course of disease is the longest 20 years, the shortest 3 months, fasting glucose 35mmol/L 10 example, fasting glucose > 30.0mmol/ L 20 example, fasting glucose 25.0 mmol/
L 50 example, fasting glucose > 20 mmol
/ L 65 example, fasting glucose 7.5 mmol/L
5 examples, glucose in urine (++++) 45 examples, glucose in urine (+++) 80 example, glucose in urine 25 example, glucose in urine (+) 5 examples, complicated hypertension, 60 examples of hyperlipidemia, clinical manifestation is polydipsia, polyphagia, 70 examples of becoming thin, show as polydipsia, polyuria, weak, poor appetite substantially do not become thin person 30 example, show as polydipsia, polyuria polyphagia without 55 examples become thin.
Take 40 examples of Or Metformin In Treating before test, take 60 examples of gliclazide treatment, by 10 examples of protamine zine insulin secondary every day each 20U treatment.
Therapeutic Method: patient disables all hypoglycemic medicines taken before this, then the granule by warm boiled water embodiment 1, each takes 3 grams, three times a day, 20 days was 1 course for the treatment of.
Curative effect judging standard:
Cure: clinical symptoms polydipsia, polyphagia, polyuria disappear, chemical examination fasting glucose is less than 6.1 mmol/ L glucose in urine (-)s；
Effective: clinical symptoms, sign are normal, laboratory fasting glucose < 6.3 mmol/L, glucose in urine (-)；
Effective: clinical symptoms, sign takes a turn for the better, fasting glucose < 6.5 mmol/L, glucose in urine (-).
Result of the test: cure 105 examples and account for 70%(wherein II type 72 example, III type 33 example), effective 45 examples account for 30%(wherein II type 31 example, III type 14 example).
Through above-mentioned experiment, the Chinese medicine composition of the present invention, treat II type, type III diabetes excellent effect, substantially have no adverse reaction, be suitable for II type type III diabetics long-term taking.
Untoward reaction: after using this product, blood glucose has and is stepped up, fasting glucose can be slowly declined after about needing several hours, at this time if any discomfort, giddy, foot occur without force phenomenon, can just start to halve medication dose, after two weeks, start progressively escalated dose again, it is possible to just can progressively alleviate after slightly doing afternoon nap 2 hours and be down to more hypoglycemia.
Points for attention: to the diabetes patient after long-acting, fugitive, the specially good effect insulin inaction of injection, and height coma patient, and the diabetes patient that Os Sus domestica has broken, this product can divide 12 dosages maybe can divide 20 dosages, i.e. can reach and progressively alleviate and cause to repair, after fasting glucose progressively declines cause normally, can 3 times to 6 times to 8 times on the 1st, this product using dosage every day is for incrementally increasing, it is administered once after can dividing 1 hour or after 3 hours, to be administered once after 3 hours after 1 hour, quantity-unlimiting with this type of administration, the amount data increasing several times can be played.III type height coma patient, and the diabetes patient that Os Sus domestica has broken, the amount having a meal every day can increase by 1 ~ 6 times, it is used for increasing fat body weight muscle power, extending life, reducing more below the most original fasting glucose with improving, every day, dish was 1 jin to 2 jin of Carnis caprae seu ovis, or Gaster Sus domestica, pig tongue, Carnis Sus domestica, pickles are that Fructus Benincasae, Caulis et Folium Lactucae sativae, Thallus Laminariae (Thallus Eckloniae), chemical-free vegetables, Abelmoschus esculentus, dish every day need decocting in water, salt to be light putting.The every ration of Ovum Anas domestica one jin, it is necessary on time take.
Taboo: when using this product, all Western medicine, Chinese medicine and all long-acting, fugitive, specially good effect insulins need to be disabled, forbid diabetes patient: avoid take that the soft-shelled turtle (Trionyx sinensis Wiegmann), Radix Dauci Sativae, white turnip, Semen Vignae Cylindricae corruption, Fructus Capsici, Rhizoma Zingiberis Recens, sauerkraut, acid bean, Bulbus Allii be young, feedstuff is supported all, chicken, duck etc., greengrocery, prohibit all vegetables after taking all Pesticide use.Have stomatitis person, Colgate-Palmolive 360 toothpaste to be disabled.
Claims (9)
1. the Chinese medicine composition treating diabetes, it is characterised in that include following raw material medicaments by weight: Herba Cistanches 495 ~ 505 parts, Fructus Lycii 1990 ~ 2010 parts, Rhizoma Polygonati 595 ~ 605 parts, raw Carapax Trionycis 990 ~ 1010 parts, Herba Dendrobii 48 ~ 52 parts, Radix Panacis Quinquefolii 98 ~ 102 parts, Korean Ginseng 48 ~ 52 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 195 ~ 205 parts, 4.5 ~ 5.5 parts of Pericarpium Zanthoxyli, Semen Cuscutae 245 ~ 255 parts, Pericarpium Granati 98 ~ 102 parts, 98 ~ 102 parts of Radix Rehmanniae Preparata.
The Chinese medicine composition for the treatment of diabetes the most according to claim 1, it is characterised in that each raw material medicines in portions by weight is: Herba Cistanches 500 parts, Fructus Lycii 2000 parts, Rhizoma Polygonati 600 parts, raw Carapax Trionycis 1000 parts, Herba Dendrobii 50 parts, Radix Panacis Quinquefolii 100 parts, Korean Ginseng 50 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 200 parts, 5 parts of Pericarpium Zanthoxyli, Semen Cuscutae 250 parts, Pericarpium Granati 100 parts, 100 parts of Radix Rehmanniae Preparata.
The Chinese medicine composition for the treatment of diabetes the most according to claim 1 and 2, it is characterised in that said composition dosage form is injection or oral formulations.
The Chinese medicine composition for the treatment of diabetes the most according to claim 3, it is characterised in that said composition dosage form is granule.
5. the preparation method of Chinese medicine composition described in a claim 1 or 2, it is characterised in that: described starting material with water is decocted, filters, filtrate is condensed into extractum, add pharmaceutic adjuvant and be prepared from.
The preparation method of Chinese medicine composition the most according to claim 5, it is characterised in that decoct three times, for the first time adds 8 ~ soak by water of 12 times amount 1.5 ~ 2.5 hours；Second time adds 6 ~ soak by water of 10 times amount 0.8 ~ 1.2 hour；Third time adds 5 ~ soak by water of 8 times amount 0.8 ~ 1.2 hour.
7. according to the preparation method of the Chinese medicine composition described in claim 5 or 6, it is characterised in that being concentrated into 60 DEG C of relative densities is the thick paste of 1.27-1.33.
The preparation method of Chinese medicine composition the most according to claim 7, it is characterised in that extractum adds dextrin and prepares granule.
9. the application in the medicine of preparation treatment diabetes of the compositions described in a claim 1 or 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610359730.XA CN105998728A (en) | 2016-05-27 | 2016-05-27 | Traditional Chinese medicinal composition for treating diabetes as well as preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610359730.XA CN105998728A (en) | 2016-05-27 | 2016-05-27 | Traditional Chinese medicinal composition for treating diabetes as well as preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105998728A true CN105998728A (en) | 2016-10-12 |
Family
ID=57094467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610359730.XA Pending CN105998728A (en) | 2016-05-27 | 2016-05-27 | Traditional Chinese medicinal composition for treating diabetes as well as preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105998728A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107125678A (en) * | 2017-05-24 | 2017-09-05 | 湖北盛通药业有限公司 | A kind of pyrus nivalis clear cream extraction process |
| CN112263389A (en) * | 2020-11-17 | 2021-01-26 | 中山大学中山眼科中心 | Ophthalmic medicine moxibustion plaster |
| WO2023178592A1 (en) * | 2022-03-24 | 2023-09-28 | Chang Gung University | Uses of bletilla formosana extract for the treatment of diseases associated with dysregulated activation of neutrophils |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721580A (en) * | 2015-03-03 | 2015-06-24 | 刘正菊 | Traditional Chinese medicine composition for treating diabetes |
-
2016
- 2016-05-27 CN CN201610359730.XA patent/CN105998728A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721580A (en) * | 2015-03-03 | 2015-06-24 | 刘正菊 | Traditional Chinese medicine composition for treating diabetes |
Non-Patent Citations (1)
| Title |
|---|
| 中华中医药学会糖尿病分会: "糖尿病中医诊疗标准", 《世界中西医结合杂志》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107125678A (en) * | 2017-05-24 | 2017-09-05 | 湖北盛通药业有限公司 | A kind of pyrus nivalis clear cream extraction process |
| CN112263389A (en) * | 2020-11-17 | 2021-01-26 | 中山大学中山眼科中心 | Ophthalmic medicine moxibustion plaster |
| CN112263389B (en) * | 2020-11-17 | 2024-05-14 | 中山大学中山眼科中心 | Ophthalmic medicinal moxibustion plaster |
| WO2023178592A1 (en) * | 2022-03-24 | 2023-09-28 | Chang Gung University | Uses of bletilla formosana extract for the treatment of diseases associated with dysregulated activation of neutrophils |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103566350B (en) | A kind of pharmaceutical composition with hypoglycemic effect | |
| JP2001506589A (en) | Pharmaceutical composition for treating diabetes | |
| CN105998728A (en) | Traditional Chinese medicinal composition for treating diabetes as well as preparation method and application | |
| CN104815166B (en) | A kind of Chinese medicine composition for treating diabetes and its preparation and application | |
| CN106692742A (en) | Traditional Chinese compound medicine for regulating blood sugar and preparation method of traditional Chinese compound medicine | |
| CN103055176B (en) | Traditional Chinese medicine for treating diabetes mellitus and preparation method thereof | |
| CN101843843A (en) | Chinese medicament for treating diabetes | |
| CN101987135B (en) | Medicine for treating tetanus and preparation method thereof | |
| CN107737280A (en) | Chinese medicine composition for treating diabetes and its preparation method and application | |
| CN100360156C (en) | Chinese medicine composition new use | |
| CN102114185B (en) | Medicament for treating insulin resistance of type 2 diabetes | |
| CN102715502B (en) | Preparation method of health food with function of anti-diabetes | |
| CN102119732B (en) | Milk powder with function of treating diabetes and preparation method thereof | |
| CN101015636A (en) | Novel use of Chinese-medicinal composition | |
| CN103989940A (en) | Traditional Chinese medicine composition for treating diabetes mellitus | |
| CN104524359B (en) | A kind of Chinese medicine composition, its preparation method and application | |
| CN102113529B (en) | Flour with function of treating diabetes and preparation method thereof | |
| CN107669860A (en) | A kind of Chinese medicine composition and its application with blood sugar reducing function | |
| CN101745028B (en) | Drug for treatment of diabetes and complications thereof and preparation method thereof | |
| CN107007748A (en) | Improve Chinese medicine composition, medicine of physically weak symptom and its preparation method and application | |
| CN102669660B (en) | Health-care food with antidiabetic effect | |
| CN100400090C (en) | Medicine composition for treating myasthenia gravis and prepn. method therefor | |
| CN101721593A (en) | Medicinal and edible biological composition for improving diabetes and preparation method of capsule thereof | |
| CN1194722C (en) | Shugan Zhitong soft extract for treating hepatitis | |
| CN106039028A (en) | Blood-glucose reducing pill and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161012 |
|
| RJ01 | Rejection of invention patent application after publication |