CN105994974A - Method for preparation of feeding immunopotentiator with orange peel and lily dreg as main raw materials - Google Patents
Method for preparation of feeding immunopotentiator with orange peel and lily dreg as main raw materials Download PDFInfo
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- CN105994974A CN105994974A CN201511020627.4A CN201511020627A CN105994974A CN 105994974 A CN105994974 A CN 105994974A CN 201511020627 A CN201511020627 A CN 201511020627A CN 105994974 A CN105994974 A CN 105994974A
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- slag
- algae
- citri tangerinae
- bulbus lilii
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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Abstract
The invention discloses a method for preparation of a feeding immunopotentiator with orange peel and lily dreg as the main raw materials. The raw materials include, by weight, 27-29 parts of orange peel, 22-24 parts of lily dreg, 30-32 parts of bean dreg, 9.3-9.5 parts of pineapple leaf, 5.8 parts of Chrysococcus, 2.7 parts of MgO, 2.1 parts of Na2S2O3 and 1.9 parts of polyethylene glycol chitosan. The water content of the orange peel, lily dreg, Chrysococcus and pineapple leaf is 3-5%, and the water content of the bean dreg is 18-20%. The method consists of: mixing the five coarse powder in proportion, then mixing the mixture with an assistant uniformly; conducting grinding for 30min, and performing sieving with a 400-mesh sieve; carrying out treatment by a mechanochemical technology for 15min-30min according to the quality and humidity of the raw materials, thus obtaining a feeding immunopotentiator finished product. The method provided by the invention uses fruit and vegetable peel pomace and other production waste to produce the feeding immunopotentiator, significantly reduces the raw material production cost of the prior art, also recycles a lot of waste produced in food production, achieves low carbon production, and increases the added value of the product.
Description
Technical field
The invention belongs to field of feed, relate to a kind of Pericarpium Citri tangerinae, Bulbus Lilii slag is that primary raw material prepares feeding exempting from
The method of epidemic disease reinforcing agent.
Background technology
China is live pig the first big producing country, but not makes the country prosperous, and reason is cultivation level and overall cultivation rule
Between mould incompatible.Owing to the aquaculture of China generally presents little and scattered, health and epidemic preventing working
It is difficult to put in place.The bottleneck problem of restriction industry development is the bacterial infection during pig-breeding, pathogenic bacterium
Often the pathogen such as the escherichia coli of zoonosis, not only affects aquaculture development, and threatens food
Safety.
Feeding antibiotic prevents and treats the history of aquaculture fowl bacterial disease existing decades, is considered for 20th century
The biotechnology that livestock and poultry breeding industry is the most prominent, numerous results of study shows, antibiotic can promote that animal is raw
Long, reduce sickness rate, mortality rate, improve the price of deed and carcase quality.Because antibiotic has price just
Preferably, instant effect, the feature such as easy to use, carry out huge economic benefit can to cultivation industrial belt.But just because of
This feature, the abuse of feeding antibiotic is the most universal.
In large-scale plant professional in the poultry farming of China and sideline production, raiser is also on a small scale
Depositing, cultivation relies on manpower to feed and nurse, and management level are relatively limited with sanitary condition ratio, though there being national legislation
Limit feeding antibiotic consumption, but part plant still excess tetracycline, soil that blindly use price is relatively low is mould
The broad ectrum antibiotic medicines such as element, chlortetracycline.After animal takes in above-mentioned medicine, it is enriched with in skeleton, in muscle
Also can extended residual, edible after cause the pathogen in human body to develop immunity to drugs, pass to disappear by health risk
Fei Zhe.
The common problem that the problem Ye Shi other countries that feeding antibiotic causes face, part European countries are
The measure that takes disables feeding growth promoting antibiotic.This measure of European countries can only reduce feeding antibiotic and pass
Passing the antibiotic resistance risk of people, the bacterial infection disease for prevention and control animal there is no help.1986
After year Sweden disables feeding antibacterial additives, the average raising 8 per ton of feed cost~11 dollars, cause poultry to be supported
Grow industry decline;After European Union's disabling part anti-bacteria agent for feeding, the pig farm of 50% is drastically gone up because of the mortality rate caused by diarrhoea
Rise, and food consumption increases, but poor growth.Scholar's statistics such as Viaene, the loss of every pig is close to 2
Dollar.In view of this present situation, exploitation has no side effect, does not develops immunity to drugs, the feed additive of noresidue,
Become the direction that various countries' research worker is made great efforts.Yolk antibody, probiotics, oligosaccharide, enzyme preparation, Tiny ecosystem
Preparation, active components of plants etc. all hold promise as feeding antibiotic succedaneum.Wherein, active components of plants
Because of its wide material sources, environmental protection, the feature such as safe and efficient, day by day become the focus of concern.
Active substance of plant has the multiple efficacies such as antibacterial, antiinflammatory, regulation immunity, but easily inactivates, suitable
Mouth property is poor;In producing reality, most Product Process are coarse, and product forms is single, difficult quality guarantee.
The present invention rely on Hunan Province fruit and vegerable cleaning processing engineering technology research center project (2015TP2022),
Orange juice born of the same parents clean production key technology study on the industrialization project (13CY028), orange juice born of the same parents' new product cleaning produces
Key technology Industrialization Projects (2015CK3031), Citrus sinensis Osbeck skin lesion of the scrotum clothing compound enzymic preparation produce key technology and turn
Change and build together applied basic research base with demonstrative project (2014GB2D200228), bean product process technologies provinces and cities
Ground construction project (2013TP4067), bean product process technologies provinces and cities build together applied basic research construction of base
Quality comparison kinetic model and forecasting shelf life in project (2013TP4068), snack dried bean curd storage
Under multiple fund projects such as project (2014FJ4253) are subsidized, seminar, through carrying out test of many times, obtains
Above-mentioned feeding immunostimulant.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, it is provided that Pericarpium Citri tangerinae, Bulbus Lilii slag produce feeding immunostimulant
Method, the method makes full use of the garbage of processing of farm products, turns waste into wealth, and can be effectively facilitated cultivation
The development of industry.
Pericarpium Citri tangerinae, Bulbus Lilii slag are that primary raw material prepares feeding immunostimulant
A kind of Pericarpium Citri tangerinae, Bulbus Lilii slag are the method that primary raw material prepares feeding immunostimulant, by Pericarpium Citri tangerinae, Bulbus Lilii
Slag, bean dregs, pineapple leaves, goldc grains algae are crushed to the coarse powder of 60~80 mesh respectively, by parts by weight of raw materials dispensing: Fructus Citri tangerinae
Skin 27~29 parts, Bulbus Lilii slag 22~24 parts, bean dregs 30~32 parts, pineapple leaves 9.3~9.5 parts, 5.8 parts of goldc grains algae, help
Agent 7 parts;Auxiliary agent is by 2.7 parts of MgO, 2.1 parts of Na2S2O3, 1.9 parts of Polyethylene glycol chitosan constitute;Pericarpium Citri tangerinae, hundred
Close slag, goldc grains algae, pineapple leaves water content 3~5%, bean dregs water content is 18~20%;Will in described ratio
Five kinds of coarse powder mixing mix with auxiliary agent again;Use mechanochemistry method to process after mixing, use high energy vibration mill
It is processed, in cooling circulating water temperature 19-21 DEG C, frequency 16Hz, processes under the conditions of rod iron acceleration 8~9g
17-18min, then shuts down 3.5min, then processes 12~13min with rod iron acceleration 6.7g, obtain feed additive
Finished product.
Optimization formula is: Pericarpium Citri tangerinae 28 parts, Bulbus Lilii slag 23 parts, 31 parts of bean dregs, pineapple leaves 9.4 parts, goldc grains
5.8 parts of algae, auxiliary agent 7 parts.
The application process of feeding immunostimulant, adds this by the weight ratio of 2~3% in live pig basal diet and exempts from
Epidemic disease reinforcing agent, it is thus achieved that rich in daidzein, soybean isoflavone, vitamin C, vitamin B, beta-carotene
Functional feed.
In formula, raw material weight reason in proportion is:
1. okara ratio particularity
Containing at least three kinds of antinutritional factor such as trypsin inhibitor, goitrin, haemoglutinins in bean dregs,
Addition is excessive, and during easily causing mechanico-chemical reaction, antinutritional factor inactivation is insufficient.
2. Bulbus Lilii slag ratio example particularity
Though the immunostimulant Han vitamin C, vitamin B etc. in Bulbus Lilii slag, but also there are the tools such as colchicine thin
The composition of born of the same parents' inhibited proliferation, addition is excessive, affects metabolic system.Goldc grains algae is as carotenoid
Source, immune level can be improved, can not be very few;If but vitamin A excess contained therein, also have
Produce the risk of negative effect.
3. Pericarpium Citri tangerinae ratio particularity
Pericarpium Citri tangerinae can increase palatability, can provide natural pigment, play the effect of phagostimulant in terms of color;
If but add too much, wherein the limonin of bitter taste affects palatability.
4. in five kinds of main components two-by-two between the particularity of ratio
Protein and the relative scale of vitamin B in Bulbus Lilii slag in bean dregs, in bean dregs, protein is special with Pericarpium Citri tangerinae
The relative scale of different composition Hesperidin, protein and the special composition beta-carotene in goldc grains algae in bean dregs
Relative scale, the ratio between these three groups of two kinds of compositions is substantially stationary.Reason is in bean dregs that protein exists
Formula has inclusion, slow release, water conservation, regulation mouthfeel, strengthens the effect of palatability;Through this team early stage
Great many of experiments room and zoopery confirm, if bean dregs are less than normal with the ratio of other four kinds of components any one, and meeting
Cause the active component in four kinds of components to be comprised insufficient, be exposed in gastric acid too early, and affect agreeable to the taste
Property, reduce feeding effect;If bigger than normal, then active component discharged slowly, DeGrain, produced economic wave
Taking, even 20% situation may affect the microorganism stable state of digestive tract back segment, causes animal digestion bad.
It addition, ratio between four kinds of main components in addition to bean dregs selected also has a particularity, herein without
Need to repeat, only one representative example of tool: containing carotenoid composition in Pericarpium Citri tangerinae, and goldc grains algae also contains
Analogous components, both proportional imbalances can cause adding generic ingredients excess, cause waste, even side effect.
The while of the present invention relates to 3 kinds of solid-state auxiliary agents, non-equal proportion, under high energy mechanical power effect with many plantations
Physical property raw material is jointly processed by, and multiple mechanico-chemical reaction the most necessarily occurs, and (this serial reaction is anti-between solid phase
Should, have essential distinction with the reaction in liquid system), cause the physics of vegetable raw material, chemistry, biology
All there is the efficiently release of complicated change, beneficially bioactive ingredients and utilize in performance.This concrete mechanism is also
Inventor team through repeatedly, many groups, multi-model test and propose first, without class in domestic and international known technology
Like report, those skilled in the art can not draw by rule of thumb or simply.
To sum up, through repeatedly mixed extraction test with rat feeding experiment, Piglet feed test, become pig to feed,
And scale-up, obtain this special ratios.The ratio of any composition is too much or very few, all can be notable
Affect using effect, even result in the unbalance of this compound preparation, cause chain negative interaction, cause damage.
The invention has the beneficial effects as follows: process Pericarpium Citri tangerinae, Bulbus Lilii slag with mechanical chemical technique, with fruit and vegerable skin slag etc.
Produce garbage and produce feeding immunostimulant, significantly reduce the raw material production cost of prior art, and
The a large amount of garbages produced in food production are recycled, it is achieved low-carbon (LC) produces, increase product and add
Value.
(1) feed additive that the present invention provides uses in feedstuff for live pigs, and relatively prior art significantly reduces
Addition, has saved production cost, and improves the safety of raising, because low dosage adds greatly fall
Low Bulbus Lilii slag, goldc grains algae, Pericarpium Citri tangerinae easily produce irritating composition (such as tannin, Fructus Citri Limoniae to animal intestinal
Bitter principle, colchicine etc.) potential risk;
(2) thickness of live pig gut epithelium tissue villus cell layer can be significantly improved;
(3) the quintessence oil constituents in Pericarpium Citri tangerinae has special aroma, can stimulate live pig appetite, press down and kill intestinal cause
The effect of pathogenic bacteria, thus the feed additive of present invention offer can improve the intestinal health situation of live pig, carries
High live pig production performance, feed conversion rate improves more than 3%;
(4) efficiency of feed utilization can be improved, to the palatability of feedstuff without any harmful effect;
(5) production technology of the present invention is simple, easy to use.
Detailed description of the invention
Embodiment is given below the present invention is elaborated.
Embodiment 1
The composition of raw materials of feeding immunostimulant is: Pericarpium Citri tangerinae 28 parts, Bulbus Lilii slag 23 parts, 31 parts of bean dregs, spinach
9.4 parts of trailing plants leaf, 5.8 parts of goldc grains algae, auxiliary agent 7 parts.
Production method is, is processed by bean dregs miniature high-speed pulverizer, makes particle diameter reach 60 mesh, prepares bean
Slag coarse powder;By materials such as the Bulbus Lilii slag being separately dried to water content 3%, goldc grains algae, Pericarpium Citri tangerinae, pineapple leaves, point
Individually do not process with miniature high-speed pulverizer, make particle diameter reach 60 mesh, prepare the coarse powder of four kinds of materials;Press
Five kinds of coarse powder are mixed by formula proportion;Add solid-state auxiliary agent MgO:Na again2S2O3: Polyethylene glycol chitosan
The auxiliary agent mix homogeneously that=2.7:2.1:1.9 part is constituted;Use mechanochemistry method to process after mixing, use high energy to shake
Dynamic mill is processed, and in cooling circulating water temperature 19-21 DEG C, frequency 16Hz, locates under the conditions of rod iron acceleration 8~9g
Reason 17-18min, then shuts down 3.5min, then processes 12~13min with rod iron acceleration 6.7g, obtains feedstuff and adds
Agent finished product.
The application process of feeding immunostimulant is, the weight ratio interpolation pressing 2-3% in live pig basal diet should
Immunostimulant, is sufficiently mixed uniformly, obtains rich in daidzein, soybean isoflavone, vitamin C, dimension life
Element B, the functional feed of beta-carotene.
Embodiment 2
The composition of raw materials of feeding immunostimulant is: Pericarpium Citri tangerinae 29 parts, Bulbus Lilii slag 22 parts, 30 parts of bean dregs, spinach
9.5 parts of trailing plants leaf, 5.8 parts of goldc grains algae, auxiliary agent 7 parts.
Production method and products application method are with embodiment 1.
Embodiment 3
The composition of raw materials of feeding immunostimulant is: Pericarpium Citri tangerinae 27 parts, Bulbus Lilii slag 21 parts, 32 parts of bean dregs, spinach
9.3 parts of trailing plants leaf, 5.7 parts of goldc grains algae, auxiliary agent 7 parts.
Production method and products application method are with embodiment 1.
In order to check the effect of the present invention, in June, 2012 is carried out on Dong family of Daliang City of Liaoning Province ditch breeding pig farm
Following test:
Test material and method
It is added into adequate diet with the feeding immunostimulant of basis of embodiment 1~3 prescription, mixes with equal proportion simultaneously
Reference is carried out for comparison.Collection the following data:
1, rat challenge test: 30/group.Detect 1 μ g LPS (50 μ g/kg)+20mg D-GalN (1g/kg).
2, piglet experiment: 8/group, detection diarrhoea head number (counteracting toxic substances 5 × 1011E.coli K88), serum IgG
(g/L)。
3, pig experiment is become: 12/group, detecting 30 days body weight increase rate (%), Ea, EAC rosettes is formed
Rate (%), the apparent index of intestinal villus.Experimental result see table:
Separately, with 80 60-62kg American Duroc pig pigs as laboratory animal, it is divided into two groups, sets matched group respectively
(full price Dog ration) and test group (formula one) are tested.Result of the test shows: with matched group phase
Ratio, the diarrhea rate of test group significantly reduces, and Wall thickness of Small intestine significantly improves, IL-6 and IgA expresses and be respectively increased,
Feed conversion rate also significantly improves, and in live pig industrialized culture, average every day occurs situation ratio reducing aobvious
Writing, cost-effective and expenses about 10%, effect is notable.
The present invention produces method and the product of feeding immunostimulant with Bulbus Lilii slag and Pericarpium Citri tangerinae, is widely used in supporting
The feed manufacturing on pig farm, cultivation.The present invention will provide a kind of for consumer of China and reduce feeding from beginning of production
Antibiotic amount, improves animal immune level, the product ensured food safety and issue-resolution.Fructus Citri tangerinae
The multiple peels such as skin, Bulbus Lilii slag are rich in polysaccharide and vitamin, it is possible to provide nutritional supplementation, strengthen animal immunizing power,
The more important thing is the carrier as active substance of plant and protective agent, improve palatability, make active substance of plant
Preparation process is difficult to disperse, after being administered orally, has slow release effect.
Claims (9)
1. Pericarpium Citri tangerinae, Bulbus Lilii slag are the method that primary raw material prepares feeding immunostimulant, by Pericarpium Citri tangerinae, Bulbus Lilii slag,
Bean dregs, pineapple leaves, goldc grains algae are crushed to the coarse powder of 60~80 mesh respectively, by parts by weight of raw materials dispensing: Pericarpium Citri tangerinae 27~29
Part, Bulbus Lilii slag 22~24 parts, bean dregs 30~32 parts, pineapple leaves 9.3~9.5 parts, 5.8 parts of goldc grains algae, auxiliary agent 7 parts;
Auxiliary agent is by 2.7 parts of MgO, 2.1 parts of Na2S2O3, 1.9 parts of Polyethylene glycol chitosan constitute;Pericarpium Citri tangerinae, Bulbus Lilii slag,
Goldc grains algae, pineapple leaves water content 3~5%, bean dregs water content is 18~20%;Thick by five kinds in described ratio
Powder mixing mixes with auxiliary agent again;Use mechanochemistry method to process after mixing, use high energy vibration mill to add
Work, in cooling circulating water temperature 19-21 DEG C, frequency 16Hz, processes 17-18min under the conditions of rod iron acceleration 8~9g,
Then shut down 3.5min, then process 12~13min with rod iron acceleration 6.7g, obtain feed additive finished product.
Method the most according to claim 1, it is characterised in that by parts by weight of raw materials dispensing: Pericarpium Citri tangerinae 28 parts,
Bulbus Lilii slag 23 parts, 31 parts of bean dregs, pineapple leaves 9.4 parts, 5.8 parts, 2.7 parts MgO of goldc grains algae, 2.1 parts
Na2S2O3, 1.9 parts of Polyethylene glycol chitosan.
Method the most according to claim 1, it is characterised in that by parts by weight of raw materials dispensing: Pericarpium Citri tangerinae 29 parts,
Bulbus Lilii slag 22 parts, 30 parts of bean dregs, pineapple leaves 9.5 parts, 5.8 parts, 2.7 parts MgO of goldc grains algae, 2.1 parts
Na2S2O3, 1.9 parts of Polyethylene glycol chitosan.
Method the most according to claim 1, it is characterised in that by parts by weight of raw materials dispensing: Pericarpium Citri tangerinae 27 parts,
Bulbus Lilii slag 21 parts, 32 parts of bean dregs, pineapple leaves 9.3 parts, 5.7 parts, 2.7 parts MgO of goldc grains algae, 2.1 parts
Na2S2O3, 1.9 parts of Polyethylene glycol chitosan.
5. a feeding immunostimulant, raw material is by following weight portion dispensing: Pericarpium Citri tangerinae 27~29 parts, Bulbus Lilii slag 22~24
Part, bean dregs 30~32 parts, pineapple leaves 9.3~9.5 parts, 5.8 parts, 2.7 parts MgO of goldc grains algae, 2.1 parts of Na2S2O3、
1.9 parts of Polyethylene glycol chitosan, Pericarpium Citri tangerinae, Bulbus Lilii slag, goldc grains algae, pineapple leaves water content 3~5%, bean dregs
Water content is 18~20%.
The feeding immunostimulant of one the most according to claim 5, it is characterised in that raw material dispensing by weight:
Pericarpium Citri tangerinae 28 parts, Bulbus Lilii slag 23 parts, 31 parts of bean dregs, pineapple leaves 9.4 parts, 5.8 parts of goldc grains algae, 2.7 parts
MgO, 2.1 parts of Na2S2O3, 1.9 parts of Polyethylene glycol chitosan.
Feeding immunostimulant the most according to claim 5, it is characterised in that raw material dispensing by weight: Fructus Citri tangerinae
Skin 29 parts, Bulbus Lilii slag 22 parts, 30 parts of bean dregs, pineapple leaves 9.5 parts, 5.8 parts, 2.7 parts MgO of goldc grains algae,
2.1 parts of Na2S2O3, 1.9 parts of Polyethylene glycol chitosan.
Feeding immunostimulant the most according to claim 5, it is characterised in that raw material dispensing by weight: Fructus Citri tangerinae
Skin 27 parts, Bulbus Lilii slag 21 parts, 32 parts of bean dregs, pineapple leaves 9.3 parts, 5.7 parts, 2.7 parts MgO of goldc grains algae,
2.1 parts of Na2S2O3, 1.9 parts of Polyethylene glycol chitosan.
9. the application process of the arbitrary described feeding immunostimulant of claim 5-8, by 2~3% in live pig basal diet
Weight ratio add this immunostimulant, it is thus achieved that raw rich in daidzein, soybean isoflavone, vitamin C, dimension
Element B, the functional feed of beta-carotene.
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Citations (2)
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CN103783329A (en) * | 2014-03-10 | 2014-05-14 | 邵阳学院 | Natural forage yolk toner produced by orange peels and flavedo and preparation method thereof |
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2015
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Patent Citations (2)
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CN103734519A (en) * | 2013-12-24 | 2014-04-23 | 邵阳学院 | Method and product for producing forage immune enhancer by adopting soybean curb residue and orange peel |
CN103783329A (en) * | 2014-03-10 | 2014-05-14 | 邵阳学院 | Natural forage yolk toner produced by orange peels and flavedo and preparation method thereof |
Non-Patent Citations (2)
Title |
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刘金祥: "《中国南方牧草》", 30 March 2004 * |
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