CN105994652A - Formula milk powder for infants and young children - Google Patents
Formula milk powder for infants and young children Download PDFInfo
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- CN105994652A CN105994652A CN201610404921.3A CN201610404921A CN105994652A CN 105994652 A CN105994652 A CN 105994652A CN 201610404921 A CN201610404921 A CN 201610404921A CN 105994652 A CN105994652 A CN 105994652A
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- oil
- fat
- shayu
- formula milk
- milk powder
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1528—Fatty acids; Mono- or diglycerides; Petroleum jelly; Paraffine; Phospholipids; Derivatives thereof
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Fats And Perfumes (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Abstract
The invention discloses formula milk powder for infants and young children. The formula milk powder for the infants and the young children comprises the following components in total fat: 20-80% (w/w) of basa fish oil, 10-70% (w/w) of vegetable oil and 5-50% (w/w) of bovine milk fat. By compounding the basa fish oil and the vegetable oil, a formula which satisfies nutritional requirements of the infants and the young children is obtained. According to the invention, digestion and absorption rates of the total fat in the formula milk powder are increased, so that nutrition absorption of the infants and the young children are better facilitated.
Description
Technical field
The present invention provides the formula milk that a kind of fat optimizes, and is particularly suitable for the formula milk of infant,
In this milk powder, fat has higher bioavailability.
Background technology
Fat is a kind of important nutritional labeling arranged side by side with albumen and carbohydrate, on the one hand, provide energy；
On the other hand, it is provided that essential fatty acid and the absorption of help fatsoluble vitamin.Fat is in the growth of infant
Being even more important in growth, the fatty supply regulation adipose energy that China's infant meals are recommended accounts for gross energy
Percentage ratio, within less than 6 months, baby should feed breast milk, and fat is within 45%, 7～12 month, to be 30%～40%, 1
It is 25%～30% to being grown up after year.Concrete amount is substantially: per kg body weight per day neonate is both needed to
7 grams, 2～3 months babies need 6 grams, the baby after 6 months needs 4 grams, increase with the age later and decrescence
3～3.5 grams.The quantity delivered of baby's every daily ingestion fat accounts for the 30% of heat.
In baby formula milk powder, it is generally required to comprise the fat of more than 20%.Research shows, butter fat
Fat is not particularly suited for baby formula milk powder, and as prioritization scheme, people commonly use Vegetable oil lipoprotein and substitute cattle
Butterfat produces for formula milk, conventional vegetable oil include soybean oil, low erucic acid rapeseed oil, Semen Maydis oil and
Petiolus Trachycarpi oil etc..The biological utilisation of oils and fats contains digestion and absorbs two links, and the research of this seminar finds,
Infant is the most perfect owing to growing, strong not to fat digestion ability, existing baby formula milk powder institute
With oils and fats Shortcomings in terms of digestibility.
Summary of the invention
The deficiency existed for existing baby formula milk powder oils and fats formula, the extensive screening and assessment of this seminar is each
Kind of fat formulation scheme, find to use fresh water fish oil as baby formula milk powder oils and fats formula components it
One, achieve more excellent digestibility, define the present invention.
The present invention is a kind of baby formula milk powder, comprises 20～the bar of 80% (w/w) in milk powder always fat
Shark fish oil, 10～the vegetable oil of 70% (w/w), and 5～the butter fat of 50% (w/w).
Oils and fats is before being absorbed by human body, it is necessary to experience digestion step.The digestion of oils and fats refers to glycerol
Three esters are resolved into the process of partial glyceride and fatty acid by lipase, and this step is first that fat is utilized
Step.The digestion of triglyceride starts from stomach, can carry out pre-to triglyceride containing a small amount of lipase in stomach
Digestion.Oils and fats in digestive tract enters small intestinal through stomach, here completes main digestion and absorption.Little
In intestinal, oils and fats is dispersed into oil droplet under the emulsification of bile acid, and oil droplet has the biggest surface area, pancreas
Lipase needs hydrolysate oil on interface to become fatty acid and monoglyceride, completes digestion.Owing to digestion is to absorb
Basis, the digestibility that high bioavailability inevitable requirement is high, it addition, heavy oils and fats necessarily increases the weight of stomach
Intestinal is born, it is possible to bring other negative effect.
Baby formula milk powder generally comprises the fat of 20～about 30%, due to butter fat not infant
The fat being suitable for, people are usually and use vegetable oil formula to substitute butter fat.At the vegetable oil bag used
Include soybean oil, Petiolus Trachycarpi oil, Semen Maydis oil, oleum lini, low erucic acid rapeseed oil, Oleum Helianthi etc., to oil
In fat, Petiolus Trachycarpi oil saturation is higher, can be that human milk fat substituted product provide satisfied fatty acid, be formulas
A kind of important component in powder.This laboratory when carrying out fat digestion performance evaluation it was unexpectedly observed that Petiolus Trachycarpi
Between oil and Ba Shayu fish oil, fatty acid composition is close, but the digestion characteristics of the two differs greatly, Ba Shayu fish oil
It is easier to digestion than Petiolus Trachycarpi oil.Further investigations have shown that, in digestion between Ba Shayu fish oil and multiple oils and fats
Aspect of performance has synergism, it is, the formula comprising Ba Shayu fish oil is more prone to digested, and bag
Human milk fat substitutes containing Ba Shayu fish oil formula is generally than the disappearing of human milk fat succedaneum of Petiolus Trachycarpi oil formula
Rate is high.High digestibility means lower gastrointestinal burden.Further research shows, in absorbance side
Face, comprises the human milk fat substitutes of Ba Shayu fish oil formula generally than the human milk fat succedaneum of Petiolus Trachycarpi oil formula
Absorbance high.
Above result of study is pointed out, and uses Ba Shayu fish oil replacement or part replacement Petiolus Trachycarpi oil to optimize and joins
The fat composition of side's milk powder.
Evaluation to oil and fat assimilation typically uses external digestion to be simulated, need to build with enzyme, cholate and
The digestion system of the material compositions such as buffer, in simulation digestion process, uses the mode of auto-feeding alkali liquor
Control the constant of digestion system pH.Because oil and fat assimilation is mainly carried out in small intestinal, pH in small intestinal
About neutrality, so also controlling pH during the external digestion of oils and fats is about 7.The trip that digestion process produces
The alkali constantly added by stream from fatty acid neutralizes, and digestive rate of fat then can be by digesting alkali in digestion process
Amount calculates.The study general of fat absorption utilization rate is used zoopery, by measuring its feces
Middle fat content is evaluated.
In the present invention, Ba Shayu fish oil is one of nucleus.Ba Shayu fish oil is a kind of fresh water fish oil,
Generally, fresh water fish oil is that the by-product as fresh-water fishes processing is treated.Fresh water fish oil often acid value is high, stench
The problems such as highly seasoned, sanitary condition is bad.So, fresh water fish oil is generally used for industry and feedstuff industry, at present,
China is not yet related to industry standard or the national standard of fresh water fish oil.
Fresh-water fishes include a lot of kind, such as tilapia, Ba Shayu, Ctenopharyngodon idellus, Mylopharyngodon piceus, Silurus asotus fish, Cyprinus carpio, crucian carp
Fish etc..Wherein, Ba Shayu is the freshwater aquiculture kind that country in Southeast Asia is important.It belongs to Silurformes Fish, belongs to
Awns Nian mesh, the awns Silurus asotus fish that awns Nian belongs to, for alepidote class.Ba Shayu is also a kind of distinctive in the Mekong River valley
Quality and economy Fish, Vietnam's transliteration is " kappa is husky " (CABASA), and the meaning is " three pieces of fatty fishes ", because of
For this fish in growth course, intraperitoneal accumulation has three blocks of bigger oils and fatss.
In the present invention, Ba Shayu fish oil is a kind of saturation type oils and fats being prone to digestion, and consumption accounts for total fat
20～80% (w/w)；Vegetable oil can provide essential fatty acid, and such as linoleic acid plus linolenic acid etc., consumption accounts for
10～70% (w/w) of total fat, it is preferable that the content of vegetable oil is 10～30% (w/w).Pass through bar
Shark fish oil and vegetable oil compounding, can obtain the formula meeting infantile nutrition demand.For natural cattle
Butterfat, it is typically not from additionally adding, but owing to producing at formula milk in, generally require and make
Use part fresh milk, and defatted milk powder still includes a certain amount of butterfat, so, in formula milk not
Can avoid butter fat to be comprised, in the present invention, the consumption limiting butter fat accounts for the 5～50% of total fat
(w/w)。
Being solid-state under the Ba Shayu fish oil room temperature of original extraction, fusing point is generally about 33 DEG C, and Petiolus Trachycarpi oil
Similar.Petiolus Trachycarpi oil can obtain the component of different melting points by fractionation technology, and Ba Shayu fish oil can also use
Similar processing method obtains the component of different melting points, convenient different application requirement.Point carry being basis
Constitute fusing point and the difference of dissolubility of the various glyceride molecules of oils and fats, oils and fats is divided into solid-liquid two-part
Method.Point carried surfactant divide carry, solvent divide carry, the method such as dry fractionation, the one-tenth of diaphragm filter press
Ripe utilization makes dry fractionation have higher competitive advantage, present invention preferably employs dry fractionation.Dry method is divided
Putting forward basic process and include crystallization and solid-liquid separation, crystallization is to utilize the method for slow cooling to make Gao Rong in oils and fats
Point component forms solid sediment, and solid-liquid separation can use method that is centrifugal or that filter.At present,
The companies such as Tirtiaux, De Smet, Oiltek all may be provided in ripe dividing and put forward equipment and technique.Although it is dry
Method separating-extracting apparatus differs from one another, but crystallizer stirs, the type of cooling is essentially identical, it is desirable to crystallization is formed big
The crystal grain spherical, uniform and stable, resistance to mechanical stress is strong, the total feature of crystallizer has: big cooling surface
Long-pending, high heat transfer coefficient, stir well-balanced, frequency control.In terms of controlled cooling technique, according to raw material
Feature and product requirement, by selective freezing condition and separation temperature, PLC controls cooldown rate.Generally
Oil cools down according to predetermined cooling water temperature curve, or carries out according to oil and cooling circulating water difference curve
Cooling, to form suitable crystal seed and to control its growth, for filtering the condition providing good.In the present invention,
Preferably employ the Ba Sha fish oil less than 25 DEG C of the fusing point after point carrying, a concrete point extracting method is not limited.
Similar with other fresh water fish oil, unprocessed bar shark fish oil also has fishy smell, and the fishy smell of fish oil is with many
The oxidation of unsaturated fatty acid is correlated with, especially relevant with the oxidation of EPA, DHA.In Ba Shayu fish oil
The polyunsaturated fatty acid comprised the biggest dependency relevant with feedstuff, manually raises owing to Ba Shayu fish is usually
Support, and more extensive to nutritional requirement, without fish flour and sea water fish oil in feedstuff, and then can control
Ba Shayu fish oil processed does not contains substantial amounts of EPA and DHA.Therefore, in the present invention, preferably Ba Shayu fish
EPA+DHA≤2% (w/w) that oil is comprised.
In the present invention, for vegetable oil and the conventional formulation milk powder vegetable oil one of the fatty formula butter optimized
Cause, including soybean oil, Petiolus Trachycarpi oil, Semen Maydis oil, oleum lini, low erucic acid rapeseed oil, Oleum Helianthi etc. in
The mixture of one or more than one.
Preferably scheme, comprises the Ba Shayu fish oil of 40% (w/w), 25% (w/w) in milk powder always fat
Soybean oil, the oleum lini of 5%, and the butter fat of 30% (w/w).
Compared with conventional art, there is advantages that
Use Ba Shayu fish oil to substitute Petiolus Trachycarpi oil in whole or in part and can be effectively improved Lipid use rate.This
The bright digestibility that improve formula milk always fat, advantageously obtains nutrition in infant.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is more specifically described in detail, but the embodiment party of the present invention
Formula is not limited to this, for the technological parameter indicated the most especially, can refer to routine techniques and carries out.
Embodiment 1
Test the digestion characteristics of Ba Shayu fish oil, Petiolus Trachycarpi oil and soybean oil.
In vitro digestion method:
1) preparation of grease emulsifying liquid.Oils and fats 9g to be evaluated, adds 3g Tween 80, adds the pH of 288g
It is the 5mM phosphate buffer of 7.0, in 10000rpm homogenizing 5min, standby.
2) in vitro digestion, according to following steps:
A. the above-mentioned emulsion of 30ml is taken in 37 DEG C of constant temperature, stirring coke oven 5.0ml hyocholic acid saline solution (187.5mg
Fel Sus domestica hydrochlorate is dissolved in the phosphate buffer that pH is 7.0) and 1.0mlCaCl2Solution (188mM
CaCl2Aqueous solution)
B. 1.5ml pancreatic lipase (containing 60mg pancreatic lipase) is added
C. in 37 DEG C of heat-collecting magnetic stirring device stirring reaction 120min, with autotitrator auto-feeding NaOH
The pH of solution (0.01M) control reaction system is constant is 7.0, and the consumption of record NaOH is used
In the release rate of calculating free fatty, as the evaluation index of oils and fats consumption rate.The results are shown in Table 2.
Table 1 bar shark fish oil and palm oil fatty acid composition
| Ba Shayu fish oila | Petiolus Trachycarpi oilb | Soybean oilc | |
| C14:0 | 3.8% | 0.8% | 0 |
| C16:0 | 26.9% | 35.3% | 10.7% |
| C16:1 | 1.2% | 0.0% | 0.1% |
| C18:0 | 7.6% | 3.3% | 3.7% |
| C18:1 | 44.1% | 47.8% | 25.7% |
| C18:2 | 11.6% | 11.2% | 51.7% |
| C18:3 | 0.5% | 0.3% | 6.6% |
| Other | 4.3% | 1.3% | 1.5% |
| Saturated fatty acid content | 38.3% | 39.4% | 14.4% |
Table 2 free fatty release rate
A bar shark fish oil derives from Zhoushan Xin Nuojia biological engineering company limited, and b Petiolus Trachycarpi oil derives from the unit's oils and fats industry planted in Guangzhou
Company limited, c soybean oil derives from the oils and fats Industrial Co., Ltd. of unit planted in Guangzhou
From table 2 result, the digestion rate of Ba Shayu fish oil is significantly higher than Petiolus Trachycarpi oil, especially in reaction
At the initial stage, the external digestion speed of Ba Shayu fish oil is the quickest.
Contrast the hydrolysis data of single oils and fats and compound lard, 1 can be concluded that) work as Ba Shayu
The hydrolysis rate of fish oil and Petiolus Trachycarpi oil 1:1 miscella is between Ba Shayu fish hydrolysis rate and Hydrolysis of Palm Oil speed
Between, but higher than the meansigma methods of the two, illustrate that Petiolus Trachycarpi oil (high saturation oils and fats) is hydrolyzed by Ba Shayu fish oil
There is synergistic function；2) hydrolysis rate of Ba Shayu fish oil and soybean oil 1:1 miscella is between Ba Sha
Between fish fish oil and soybean oil, but higher than the meansigma methods of the two, illustrate that Ba Shayu fish oil and soybean oil are (low full
And degree oils and fats) hydrolysis between there is synergistic function；3) Petiolus Trachycarpi oil and the water of soybean oil 1:1 miscella
Solve speed then close to the meansigma methods of the two.
For the digestibility of different oils and fatss, the saturated fatty acid content tool of existing document widespread reports and oils and fats
Having dependency, this theory can explain the digestion rate difference between Petiolus Trachycarpi oil and soybean oil.But, this research
In, in Ba Shayu fish oil and Petiolus Trachycarpi oil, saturated fatty acid content is close, but occurs in that the poorest of digestion rate
Different, it is impossible to use existing theoretical explanation, need to study its mechanism of announcement further.
Embodiment 2
Use NIH mice 240,3 week old, male and female half and half, be randomly divided into 8 groups, often group 30.
Normal feedstuff uses AIN-93G feedstuff, and its formula is: corn starch 400g/kg, casein 200g/kg,
Maltodextrin 132g/kg, sucrose 100g/kg, dietary fiber 50g/kg, mineral 35g/kg, dimension is raw
Element 10g/kg, CYSTINE 3g/kg, choline chloride 2.5g/kg.On the basis of normal feedstuff, add table
3 fat or oil compositions are prepared as test feedstuff.Mice, after 7 days adaptabilities are raised, starts zoopery.
Zoopery is carried out 7 days, record feed intake and collection feces, uses acid-hydrolysis method to measure residual in feces
Fatty acid.Oils and fats according to the oils and fats searched for food and discharge calculates the availability of oils and fats, result such as table 4.
Table 3 fat or oil composition formula
Table 4
| Mice group | Add oils and fats | Lipid use rate |
| Embodiment 1 | Fat or oil composition 1 | 78.2% |
| Matched group 1 | Fat or oil composition 2 | 75.3% |
| Embodiment 2 | Fat or oil composition 3 | 82.3% |
| Matched group 2 | Fat or oil composition 4 | 69.3% |
| Embodiment 3 | Fat or oil composition 5 | 88.3% |
| Matched group 3 | Fat or oil composition 6 | 72.5% |
| Embodiment 4 | Fat or oil composition 7 | 86.8% |
| Matched group 4 | Fat or oil composition 8 | 72.1% |
Visible according to table 4 data, can be concluded that employing Ba Shayu fish oil replaces in whole or in part
Lipid use rate can be effectively improved for Petiolus Trachycarpi oil.
Claims (6)
1. a baby formula milk powder, it is characterised in that comprise 20～80% (w/w) in milk powder always fat
Ba Shayu fish oil, 10～the vegetable oil of 70% (w/w), and 5～the butter fat of 50% (w/w).
Formula milk the most according to claim 1, it is characterised in that described Ba Shayu fish oil fat
Fat acid composition should meet EPA+DHA≤2% (w/w).
Formula milk the most according to claim 1 and 2, it is characterised in that described vegetable oil
Content is 10～30% (w/w).
Formula milk the most according to claim 1 and 2, it is characterised in that described vegetable oil is
One in soybean oil, Petiolus Trachycarpi oil, Semen Maydis oil, oleum lini, low erucic acid rapeseed oil, Oleum Helianthi or
The mixture that person is two or more.
Formula milk the most according to claim 1 and 2, it is characterised in that in milk powder always fat
Comprise the Ba Shayu fish oil of 40% (w/w), the soybean oil of 25% (w/w), the oleum lini of 5%, with
And the butter fat of 30% (w/w).
Formula milk the most according to claim 1 and 2, described Ba Sha fish oil adds for using to divide to carry
The fusing point after the work oils and fats less than 25 DEG C.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610404921.3A CN105994652A (en) | 2016-06-08 | 2016-06-08 | Formula milk powder for infants and young children |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610404921.3A CN105994652A (en) | 2016-06-08 | 2016-06-08 | Formula milk powder for infants and young children |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101940241A (en) * | 2010-07-12 | 2011-01-12 | 深圳精益油脂技术有限公司 | Pangasianodon gigas lipid, application and method for preparing breast milk lipid substitutes thereof |
| CN101940242A (en) * | 2010-07-12 | 2011-01-12 | 深圳精益油脂技术有限公司 | Grease composition of infant formula food |
| CN105028659A (en) * | 2015-05-14 | 2015-11-11 | 江南大学 | Human milk substitute fat composition |
-
2016
- 2016-06-08 CN CN201610404921.3A patent/CN105994652A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101940241A (en) * | 2010-07-12 | 2011-01-12 | 深圳精益油脂技术有限公司 | Pangasianodon gigas lipid, application and method for preparing breast milk lipid substitutes thereof |
| CN101940242A (en) * | 2010-07-12 | 2011-01-12 | 深圳精益油脂技术有限公司 | Grease composition of infant formula food |
| CN105028659A (en) * | 2015-05-14 | 2015-11-11 | 江南大学 | Human milk substitute fat composition |
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