CN105987976A - Column oven capable of rapidly replacing chromatographic column - Google Patents
Column oven capable of rapidly replacing chromatographic column Download PDFInfo
- Publication number
- CN105987976A CN105987976A CN201610504727.2A CN201610504727A CN105987976A CN 105987976 A CN105987976 A CN 105987976A CN 201610504727 A CN201610504727 A CN 201610504727A CN 105987976 A CN105987976 A CN 105987976A
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- China
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- column
- guide
- cam
- centre line
- longitudinal centre
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N30/54—Temperature
Abstract
The invention discloses a column oven capable of rapidly replacing a chromatographic column. The column oven is provided with a fixed plate, a left side block and a guide fixed block, wherein the left side block and the guide fixed block are fixedly connected with the fixed plate in sequence from left to right and have collinear longitudinal center lines; a locking screw cap, a spring, a left connector and a right connector are arranged on the longitudinal center line of the left side block in sequence from left to right; two guide rods are symmetrically arranged on the upper and lower sides of the longitudinal center line of the guide fixed block; a column support is fixed on the longitudinal center line of the guide fixed block; the chromatographic column is inserted into the column support; the column oven is also provided with a door shield; the upper and lower sides of the door shield are in shaft connection of the left side block through an upper cam and a lower cam respectively; eccentric parts of the upper cam and the lower cam are rotatably connected with an upper pin shaft and a lower pin shaft; the upper pin shaft and the lower pin shaft are fixedly connected with an upper connection rod and a lower connection rod; the other ends of the upper connection rod and the lower connection rod are connected with slide blocks; right connectors are arranged on the longitudinal center lines of the slide blocks; and the slide blocks are provided with slide sleeves matched with the guide rods.
Description
Technical field
The open a kind of chromatograph column oven of the present invention, especially a kind of sealing is reliable, the column oven of fast changeable chromatographic column.
Background technology
Chromatographic separation makes to be dissolved in each component in flowing mutually exactly through chromatographic column (fixing phase), due to each component with fixing have an effect mutually vary in size, fixing mutually in the holdup time different, therefore successively from fixing mutually outflow, thus separated.Chromatogram column temperature is required the highest by efficient liquid phase chromatographic analysis system, chromatographic column calorstat (column oven) then can be accurate, stable the use temperature of control chromatographic column, for improving the post effect of chromatographic column, improving the separating degree of chromatographic peak, shorten retention time, reduce back-pressure and ensure that the repeatability etc. analyzing sample result has considerable effect.Owing to chromatographic column needs often to change according to different separation objects, existing column oven is to be fixed at chromatographic column two ends by pipe joint etc., it is not only possible to because joint coordinates the bad generation phenomenon of leakage, and changes chromatographic column every time and bothers the most very much, wastes time and energy.
Summary of the invention
The present invention is to solve the above-mentioned technical problem existing for prior art, it is provided that a kind of seal the reliable and column oven of fast changeable chromatographic column.
The technical solution of the present invention is: the column oven of a kind of fast changeable chromatographic column, it is provided with fixed plate, be fixedly connected the most successively the left side block of longitudinal centre line conllinear and guide fixed block with fixed plate, the longitudinal centre line of left side block is disposed with lock nut, spring and left interface from left to right, it is connected to connecting screw with left interface, longitudinal centre line at guide fixed block is symmetrically arranged on two with two guide rods up and down, being fixed with column bracket on the longitudinal centre line of guide fixed block, chromatographic column is plugged in column bracket；There is door shield, the both sides up and down of door shield are connected with left side block axle by overhead cam, lower cam respectively, eccentric part at overhead cam rotates and is connected to upper pin, eccentric part at lower cam rotates and is connected to lower bearing pin, it is fixedly connected upper connecting rod with upper pin, it is fixedly connected lower link symmetrically arranged with upper connecting rod with lower bearing pin, the other end of upper connecting rod and lower link connects with the top and bottom of sliding shoe, the longitudinal centre line of sliding shoe is provided with right interface, it is connected to right connector with right interface, is provided with two sliding sleeves with matching guide bars in the upper and lower both sides of sliding shoe longitudinal centre line.
The present invention manually rotates clockwise a shelves, both can realize the compact siro spinning technology of chromatographic column and left and right joint, prevents because joint coordinates the bad generation phenomenon of leakage；When manually rotating counterclockwise a shelves, realize chromatographic column and disconnect with left and right joint, chromatographic column is taken out in column bracket taking-up and changes, easy to operate, time saving and energy saving, improve work efficiency.
Accompanying drawing explanation
Fig. 1 is the front view of the embodiment of the present invention.
Fig. 2 is the D-D view of Fig. 1.
Fig. 3 is the top view of the embodiment of the present invention.
Detailed description of the invention
As shown in Figure 1, 2, 3: be provided with fixed plate 1, it is fixedly connected the most successively the left side block 2 of longitudinal centre line conllinear and guide fixed block 3 with fixed plate 1, the longitudinal centre line of left side block 2 is disposed with lock nut 4, spring 5 and left interface 6 from left to right, it is connected to connecting screw 7 with left interface 6, longitudinal centre line at guide fixed block 3 is symmetrically arranged on two with two guide rods 8 up and down, the longitudinal centre line of guide fixed block 3 is machined with locating slot, column bracket 9 is fixed in locating slot, and chromatographic column 10 is plugged in column bracket 9；There is door shield 11, the both sides up and down of door shield 11 are connected with left side block 2 axle by overhead cam 12, lower cam 13 respectively, eccentric part at overhead cam 12 rotates and is connected to upper pin 14, eccentric part at lower cam 13 rotates and is connected to lower bearing pin 15, it is fixedly connected upper connecting rod 16 with upper pin 14, it is fixedly connected and the upper symmetrically arranged lower link of connecting rod 16 17 with lower bearing pin 15, i.e. overhead cam 12, upper pin 14 and upper connecting rod 16 constitutes brace and connecting rod framework, lower cam 13, lower bearing pin 15 and lower link 17 constitute brace and connecting rod framework, and two set brace and connecting rod frameworks are symmetrical above and below.The other end of upper connecting rod 16 and lower link 17 connects with the top and bottom of sliding shoe 18, the longitudinal centre line of sliding shoe 18 is provided with right interface 19, it is connected to right connector 20 with right interface 19, is provided with two sliding sleeves 21 mated with guide rod 8 in the upper and lower both sides of sliding shoe 18 longitudinal centre line.
Work process:
Fixed plate 1 being arranged on instrument front panel, connecting screw 7, right connector 20 connect with flowing phase pipeline.
1. when changing chromatographic column, door shelves 11 the most counterclockwise, overhead cam 12 and lower cam 13 rotate around upper pin 14 and lower bearing pin 15, by driving sliding shoe 18 to move right along guide rod 8 with overhead cam 12 and the upper and lower connecting rod 16,17 hinged with lower cam 13, make coaxial left interface 6 disconnect with chromatographic column 10 and right interface 19, can easily extract chromatographic column 10 out and be replaced.
2. New GC column 10 is inserted in column bracket 9, manually rotate clockwise a shelves 11, overhead cam 12 and lower cam 13 rotate around upper pin 14 and lower bearing pin 15, by the upper connecting rod 16 hinged with overhead cam 12 and lower cam 13 and drive sliding shoe 18 to be moved to the left along guide rod 8 with connecting rod 17, make coaxial left interface 6, chromatographic column 10 and right interface 19 close proximity.
Claims (1)
1. the column oven of a fast changeable chromatographic column, it is characterized in that: be provided with fixed plate (1), it is fixedly connected the most successively the left side block (2) of longitudinal centre line conllinear and guide fixed block (3) with fixed plate (1), the longitudinal centre line of left side block (2) is disposed with lock nut (4) from left to right, spring (5) and left interface (6), it is connected to connecting screw (7) with left interface (6), longitudinal centre line at guide fixed block (3) is symmetrically arranged on two with two guide rods (8) up and down, the longitudinal centre line of guide fixed block (3) is fixed with column bracket (9), chromatographic column (10) is plugged in column bracket (9)；nullThere is door shield (11)，The both sides up and down of door shield (11) are respectively by overhead cam (12)、Lower cam (13) is connected with left side block (2) bearing pin，Eccentric part at overhead cam (12) rotates and is connected to upper pin (14)，Eccentric part at lower cam (13) rotates and is connected to lower bearing pin (15)，It is fixedly connected upper connecting rod (16) with upper pin (14)，It is fixedly connected and upper connecting rod (16) symmetrically arranged lower link (17) with lower bearing pin (15)，The other end of upper connecting rod (16) and lower link (17) connects with the top and bottom of sliding shoe (18)，The longitudinal centre line of sliding shoe (18) is provided with right interface (19)，It is connected to right connector (20) with right interface (19)，Two sliding sleeves (21) mated with guide rod (8) it are provided with in the upper and lower both sides of sliding shoe (18) longitudinal centre line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610504727.2A CN105987976B (en) | 2016-07-01 | 2016-07-01 | The column oven of fast changeable chromatographic column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610504727.2A CN105987976B (en) | 2016-07-01 | 2016-07-01 | The column oven of fast changeable chromatographic column |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105987976A true CN105987976A (en) | 2016-10-05 |
| CN105987976B CN105987976B (en) | 2017-12-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201610504727.2A Active CN105987976B (en) | 2016-07-01 | 2016-07-01 | The column oven of fast changeable chromatographic column |
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| Country | Link |
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| CN (1) | CN105987976B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109406693A (en) * | 2018-12-09 | 2019-03-01 | 大连技嘉科技有限公司 | Glycolated hemoglobin analysis column oven |
| WO2021120609A1 (en) * | 2020-07-13 | 2021-06-24 | 南通大学 | Chromatography column temperature equalizer for ensuring temperature uniformity |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62297753A (en) * | 1986-06-17 | 1987-12-24 | Kurita Water Ind Ltd | Chromatographic device |
| US5951873A (en) * | 1997-12-23 | 1999-09-14 | Modcol Corporation | Chromatographic device with piston locking mechanism and method of packing same |
| CN2498583Y (en) * | 2001-09-28 | 2002-07-03 | 长沙天心区机电教学仪器厂 | Crank, guide pole and slide block mechanism test table |
| CN103558322A (en) * | 2013-11-01 | 2014-02-05 | 上海化工研究院 | Low-temperature pressurization head space sample injection device for measuring volatile substances in atmosphere through GC-MS (gas chromatography-mass spectrometer) technology |
| CN203479771U (en) * | 2010-10-29 | 2014-03-12 | 赛默菲尼根有限责任公司 | Device for connecting chromatographic column to pipeline |
| CN103692404A (en) * | 2013-12-31 | 2014-04-02 | 天津鹏翎胶管股份有限公司 | Nylon tube and quick connector plugging tool |
| CN104154195A (en) * | 2014-07-21 | 2014-11-19 | 苏州市华宁机械制造有限公司 | Double-eccentric driving guide-bar mechanism |
| CN204868586U (en) * | 2015-08-07 | 2015-12-16 | 联合通用电梯股份有限公司 | Manual quick linkage clamping device |
| CN206321613U (en) * | 2016-07-01 | 2017-07-11 | 大连技嘉科技有限公司 | The column oven of fast changeable chromatographic column |
-
2016
- 2016-07-01 CN CN201610504727.2A patent/CN105987976B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62297753A (en) * | 1986-06-17 | 1987-12-24 | Kurita Water Ind Ltd | Chromatographic device |
| US5951873A (en) * | 1997-12-23 | 1999-09-14 | Modcol Corporation | Chromatographic device with piston locking mechanism and method of packing same |
| CN2498583Y (en) * | 2001-09-28 | 2002-07-03 | 长沙天心区机电教学仪器厂 | Crank, guide pole and slide block mechanism test table |
| CN203479771U (en) * | 2010-10-29 | 2014-03-12 | 赛默菲尼根有限责任公司 | Device for connecting chromatographic column to pipeline |
| CN103558322A (en) * | 2013-11-01 | 2014-02-05 | 上海化工研究院 | Low-temperature pressurization head space sample injection device for measuring volatile substances in atmosphere through GC-MS (gas chromatography-mass spectrometer) technology |
| CN103692404A (en) * | 2013-12-31 | 2014-04-02 | 天津鹏翎胶管股份有限公司 | Nylon tube and quick connector plugging tool |
| CN104154195A (en) * | 2014-07-21 | 2014-11-19 | 苏州市华宁机械制造有限公司 | Double-eccentric driving guide-bar mechanism |
| CN204868586U (en) * | 2015-08-07 | 2015-12-16 | 联合通用电梯股份有限公司 | Manual quick linkage clamping device |
| CN206321613U (en) * | 2016-07-01 | 2017-07-11 | 大连技嘉科技有限公司 | The column oven of fast changeable chromatographic column |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109406693A (en) * | 2018-12-09 | 2019-03-01 | 大连技嘉科技有限公司 | Glycolated hemoglobin analysis column oven |
| WO2021120609A1 (en) * | 2020-07-13 | 2021-06-24 | 南通大学 | Chromatography column temperature equalizer for ensuring temperature uniformity |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105987976B (en) | 2017-12-22 |
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Effective date of registration: 20200609 Address after: 215011 building 2-2-211, No.2, Peiyuan Road, high tech Zone, Suzhou City, Jiangsu Province Patentee after: Suzhou Borui Jiasheng Medical Technology Co.,Ltd. Address before: 116023 No. 20 love street, hi tech park, Liaoning, Dalian Patentee before: DALIAN JIJIA TECHNOLOGY Co.,Ltd. |