CN105982975A - 一种川乌的炮制方法 - Google Patents

一种川乌的炮制方法 Download PDF

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CN105982975A
CN105982975A CN201610045291.5A CN201610045291A CN105982975A CN 105982975 A CN105982975 A CN 105982975A CN 201610045291 A CN201610045291 A CN 201610045291A CN 105982975 A CN105982975 A CN 105982975A
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monkshood
minute
decocting liquid
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李恒勇
李大伟
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Anhui Yiyuan Pharmaceutical Co Ltd
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Abstract

本发明公开了一种川乌的炮制方法，包括以下内容：净制、花类提取液的提取、煎液的制备、炮制；本发明采用花类提取物及煎液作为炮制川乌的辅料，得到的川乌炮制品毒性显著降低，而且本发明的方法简便易行，可以缩短原料药材的浸泡时间，以免有效成分大量流失，保证产品质量和疗效，减少成品的损耗率，提高了生产效益。

Description

一种川乌的炮制方法
技术领域
本发明涉及一种川乌的炮制方法，属于中药炮制技术。
背景技术
川乌，为毛茛科植物卡氏乌头制后内服。生川乌酊外用能刺激皮肤，继而产生麻木感，故外用作某些神经痛及风的母根。6月下旬至8月上旬采挖，除去子根、须根及泥沙，晒干后称为“川乌”。 辛、苦，热；有大毒。归心、肝、肾、脾经；川乌具有祛风除湿，温经止痛的药效。用于风寒湿痹、关节疼痛、心腹冷痛、寒疝作痛的治疗。
发明内容
本发明的目的在于提供一种川乌的炮制方法。
为了实现上述目的本发明采用如下技术方案 ：
川乌的炮制方法，包括以下内容：
（1）净制：取川乌原药材，清水冲洗，去除杂质，然后将川乌放入含0.4-0.5%山梨酸钾、1-2%柠檬酸的混合水溶液中浸泡20-30分钟，取出后沥干，备用；
（2）花类提取液的提取：取百合花、玫瑰花、桂花，捣碎，混合提取 3次，第一次加原料重量 10倍的水，第二次加原料重量 10 倍的水，第三次加原料重量 8 倍的水，提取时间分别为 100-120分钟、90-100分钟、50-60分钟，合并提取液，得混合提取液；所述的百合花、玫瑰花、桂花混合比例为1:1:1；
（3）煎液的制备：按等比例取新鲜片姜黄、艾草，加入6-10倍量的纯净水，混合煎熬45-55分钟，过滤取煎液；
（4）炮制：将步骤（1）净制后的川乌用清水喷润至内无干心，放入高压锅内，加入步骤（2）中制备的所述花类提取液和步骤（3）所述的煎液至高于高压锅内川乌药物表面 1-2cm，然后缓缓加热，至沸后保持温度100-120℃，压力40～50kPa，蒸煮4-5小时，停止加热，取出炮制品，微波烘干，即得。
所述的微波烘干为置于微波干燥炉内，在输出 600-700w的微波功率下烘干，时间为3-4分钟。
所述的花类提取液和煎液的加入炮制加入比例为3:2。
本发明的有益效果：
本发明采用花类提取物及煎液作为炮制川乌的辅料，得到的川乌炮制品毒性显著降低，而且本发明的方法简便易行，可以缩短原料药材的浸泡时间，以免有效成分大量流失，保证产品质量和疗效，减少成品的损耗率，提高了生产效益。
具体实施方式
实施例1：川乌的炮制方法，包括以下内容：
（1）净制：取川乌原药材，清水冲洗，去除杂质，然后将川乌放入含0.45%山梨酸钾、1.5%柠檬酸的混合水溶液中浸泡25分钟，取出后沥干，备用；
（2）花类提取液的提取：取百合花、玫瑰花、桂花，捣碎，混合提取 3次，第一次加原料重量 10倍的水，第二次加原料重量 10 倍的水，第三次加原料重量 8 倍的水，提取时间分别为 110分钟、95分钟、55分钟，合并提取液，得混合提取液；所述的百合花、玫瑰花、桂花混合比例为1:1:1；
（3）煎液的制备：按等比例取新鲜片姜黄、艾草，加入8倍量的纯净水，混合煎熬50分钟，过滤取煎液；
（4）炮制：将步骤（1）净制后的川乌用清水喷润至内无干心，放入高压锅内，加入步骤（2）中制备的所述花类提取液和步骤（3）所述的煎液至高于高压锅内川乌药物表面 1-2cm，然后缓缓加热，至沸后保持温度110℃，压力40～50kPa，蒸煮4.5小时，停止加热，取出炮制品，微波烘干，即得。
所述的微波烘干为置于微波干燥炉内，在输出 650w的微波功率下烘干，时间为3分钟。
所述的花类提取液和煎液的加入炮制加入比例为3:2。

Claims (3)

1.一种川乌的炮制方法，其特征在于包括以下内容：
（1）净制：取川乌原药材，清水冲洗，去除杂质，然后将川乌放入含0.4-0.5%山梨酸钾、1-2%柠檬酸的混合水溶液中浸泡20-30分钟，取出后沥干，备用；
（2）花类提取液的提取：取百合花、玫瑰花、桂花，捣碎，混合提取 3次，第一次加原料重量 10倍的水，第二次加原料重量 10 倍的水，第三次加原料重量 8 倍的水，提取时间分别为 100-120分钟、90-100分钟、50-60分钟，合并提取液，得混合提取液；所述的百合花、玫瑰花、桂花混合比例为1:1:1；
（3）煎液的制备：按等比例取新鲜片姜黄、艾草，加入6-10倍量的纯净水，混合煎熬45-55分钟，过滤取煎液；
（4）炮制：将步骤（1）净制后的川乌用清水喷润至内无干心，放入高压锅内，加入步骤（2）中制备的所述花类提取液和步骤（3）所述的煎液至高于高压锅内川乌药物表面 1-2cm，然后缓缓加热，至沸后保持温度100-120℃，压力40～50kPa，蒸煮4-5小时，停止加热，取出炮制品，微波烘干，即得。
2.根据权利要求1所述的川乌的炮制方法，其特征在于，所述的微波烘干为置于微波干燥炉内，在输出 600-700w的微波功率下烘干，时间为3-4分钟。
3.根据权利要求1所述的川乌的炮制方法，其特征在于，所述的花类提取液和煎液的加入炮制加入比例为3:2。
CN201610045291.5A 2016-01-25 2016-01-25 一种川乌的炮制方法 Pending CN105982975A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050091A (zh) * 2017-04-19 2017-08-18 四川省天府神龙中药饮片有限公司 一种没药的炮制方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520303A (zh) * 2013-09-27 2014-01-22 杨世德 一种川乌炮制方法
CN105168413A (zh) * 2015-10-19 2015-12-23 张妤 一种川乌超微粉及其制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520303A (zh) * 2013-09-27 2014-01-22 杨世德 一种川乌炮制方法
CN105168413A (zh) * 2015-10-19 2015-12-23 张妤 一种川乌超微粉及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050091A (zh) * 2017-04-19 2017-08-18 四川省天府神龙中药饮片有限公司 一种没药的炮制方法

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