CN105980002A - 用于分子、药物、疫苗等的细胞内和细胞间递送的方法和仪器 - Google Patents

用于分子、药物、疫苗等的细胞内和细胞间递送的方法和仪器 Download PDF

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Publication number
CN105980002A
CN105980002A CN201580006730.5A CN201580006730A CN105980002A CN 105980002 A CN105980002 A CN 105980002A CN 201580006730 A CN201580006730 A CN 201580006730A CN 105980002 A CN105980002 A CN 105980002A
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CN
China
Prior art keywords
plasma
electrical pulses
skin
vaccines
electrical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201580006730.5A
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English (en)
Chinese (zh)
Inventor
萨米尔·格尔格特吉
蔡宗展
达芙妮·P·安托纳卡斯
罗伯特·L·格雷
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Ep Science And Technology Ltd
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Ep Science And Technology Ltd
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Filing date
Publication date
Application filed by Ep Science And Technology Ltd filed Critical Ep Science And Technology Ltd
Publication of CN105980002A publication Critical patent/CN105980002A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/20—Non-portable devices, e.g. spraying booths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/44—Applying ionised fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
CN201580006730.5A 2014-01-30 2015-01-30 用于分子、药物、疫苗等的细胞内和细胞间递送的方法和仪器 Pending CN105980002A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461933384P 2014-01-30 2014-01-30
US61/933,384 2014-01-30
PCT/US2015/013846 WO2015116970A1 (en) 2014-01-30 2015-01-30 Method and apparatus for intracellular and intercellular delivery of molecules, drugs, vaccines and the like

Publications (1)

Publication Number Publication Date
CN105980002A true CN105980002A (zh) 2016-09-28

Family

ID=52589754

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580006730.5A Pending CN105980002A (zh) 2014-01-30 2015-01-30 用于分子、药物、疫苗等的细胞内和细胞间递送的方法和仪器

Country Status (10)

Country Link
US (1) US20150209595A1 (enExample)
EP (1) EP3099376A1 (enExample)
JP (1) JP2017506094A (enExample)
KR (1) KR20160113668A (enExample)
CN (1) CN105980002A (enExample)
AU (1) AU2015210809A1 (enExample)
CA (1) CA2937911A1 (enExample)
IL (1) IL246793A0 (enExample)
MX (1) MX2016009982A (enExample)
WO (1) WO2015116970A1 (enExample)

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US11490947B2 (en) 2015-05-15 2022-11-08 Clear Intradermal Technologies, Inc. Tattoo removal using a liquid-gas mixture with plasma gas bubbles
HK1252734A1 (zh) 2015-05-15 2019-05-31 ClearIt, LLC 使用冷等離子體進行紋身移除的系統和方法
US20170135678A1 (en) * 2015-11-18 2017-05-18 EP Technologies LLC Recovering analytes by reverse plasmaporation
US20170246468A1 (en) * 2016-02-25 2017-08-31 EP Technologies LLC Methods and systems for controlling or tuning the electric field generated in skin or tissue during cold plasma skin treatments
US20170246440A1 (en) * 2016-02-29 2017-08-31 EP Technologies LLC Apparatuses and methods for plasmaporation using microneedles
US10765850B2 (en) * 2016-05-12 2020-09-08 Gojo Industries, Inc. Methods and systems for trans-tissue substance delivery using plasmaporation
KR101967659B1 (ko) * 2016-08-02 2019-04-11 주식회사 피글 플라즈마 약물 적용 장치
US10692704B2 (en) 2016-11-10 2020-06-23 Gojo Industries Inc. Methods and systems for generating plasma activated liquid
KR101813558B1 (ko) * 2017-04-12 2018-01-03 주식회사 서린메디케어 프락셔널 플라즈마를 이용한 피부 치료장치
US11540380B2 (en) * 2017-09-29 2022-12-27 Korea Institute Of Materials Science Flexible active species generator and use thereof
KR102132370B1 (ko) * 2018-03-13 2020-08-05 주식회사 지씨에스 피부관리장치, 피부관리장치의 구동방법 및 컴퓨터 판독가능 기록매체
KR102055121B1 (ko) * 2018-04-19 2019-12-12 (주)퀀텀플라즈마 다중 주파수를 이용한 플라즈마 피부 치료 장치
KR102055123B1 (ko) * 2018-04-27 2019-12-12 (주)퀀텀플라즈마 피부개선제와 플라즈마를 이용하는 피부 치료 장치 및 방법
NL2021675B1 (en) * 2018-09-20 2020-05-07 Plasmacure B V Driver circuit for a dielectric barrier discharge plasma treatment
WO2020131544A1 (en) 2018-12-19 2020-06-25 ClearIt, LLC Systems and methods for tattoo removal using an applied electric field
US20210361962A1 (en) * 2020-05-21 2021-11-25 DahShiarn Chiao Devices and methods for contactless delivering pulsed electric fields to skin tissue

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030087864A1 (en) * 2001-07-09 2003-05-08 Brian Talbot DNA vaccine against staphylococcus aureus
US20090004717A1 (en) * 2003-07-16 2009-01-01 University Of South Florida Device and Method to Facilitate Directed Delivery and Electroporation Using a Charged Stream
CN102143718A (zh) * 2008-09-05 2011-08-03 奇诺格有限责任公司 用于处理包含活细胞的生物材料的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7923251B2 (en) * 2005-02-23 2011-04-12 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for avalanche-mediated transfer of agents into cells
US9236227B2 (en) * 2007-04-23 2016-01-12 Plasmology4, Inc. Cold plasma treatment devices and associated methods
US20120089009A1 (en) * 2010-10-11 2012-04-12 Omary Reed A Methods and apparatus to deliver nanoparticles to tissue using electronanotherapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030087864A1 (en) * 2001-07-09 2003-05-08 Brian Talbot DNA vaccine against staphylococcus aureus
US20090004717A1 (en) * 2003-07-16 2009-01-01 University Of South Florida Device and Method to Facilitate Directed Delivery and Electroporation Using a Charged Stream
CN102143718A (zh) * 2008-09-05 2011-08-03 奇诺格有限责任公司 用于处理包含活细胞的生物材料的方法

Also Published As

Publication number Publication date
MX2016009982A (es) 2016-10-07
JP2017506094A (ja) 2017-03-02
WO2015116970A1 (en) 2015-08-06
EP3099376A1 (en) 2016-12-07
IL246793A0 (en) 2016-08-31
AU2015210809A1 (en) 2016-09-15
KR20160113668A (ko) 2016-09-30
US20150209595A1 (en) 2015-07-30
CA2937911A1 (en) 2015-08-06

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Application publication date: 20160928