CN105943983A - Traditional Chinese medicine ointment for treating psoriasis and preparation method thereof - Google Patents

Traditional Chinese medicine ointment for treating psoriasis and preparation method thereof Download PDF

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CN105943983A
CN105943983A CN201610454239.5A CN201610454239A CN105943983A CN 105943983 A CN105943983 A CN 105943983A CN 201610454239 A CN201610454239 A CN 201610454239A CN 105943983 A CN105943983 A CN 105943983A
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extract
parts
radix
poria
cortex moutan
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吴克
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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Abstract

The invention discloses a traditional Chinese medicine ointment for treating psoriasis. The traditional Chinese medicine ointment comprises the following components: a radix stemonae extract, a sophora flavescens extract, a fructus psoraleae extract, a pulsatilla chinensis extract, a cortex moutan extract, ethanol, a salvia miltiorrhiza extract, a poria cocos extract, a fructus kochiae extract, a radix saposhnikoviae extract, 1.5 parts of cicada slough extract, a sophora japonica extract, disodium monolauryl sulfosuccinate and a liquorice extract. The invention provides a traditional Chinese medicine ointment for treating psoriasis. The traditional Chinese medicine ointment has the functions of clearing heat and removing toxin, converging and promoting granulation, resolving putridity and stopping bleeding and dispelling wind and relieving itching, realizes a remarkable curative effect on the skin diseases such as psoriasis and eczema and avoids side effects on skin.

Description

One treats psoriasic Chinese medicinal ointment and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicinal ointment and preparation method thereof, particularly relate to one Treat psoriasic Chinese medicinal ointment and preparation method thereof.
Background technology
Psoriasis, is a kind of common chronic inflammatory dermatoses being prone to recurrence with characteristic skin lesion. From the beginning of for inflammatory red papules, about foxtail millet grain is to Semen phaseoli radiati size, and the most gradually expanding or merging becomes brownish red Speckle, clear border, around there is inflammatory blush, substantially, surface covers the ash that multilamellar is dried in substrate infiltration White or silvery white squama.Scraper surface squama gently, gradually exposes shinny translucent of one layer of pale red Thin film, claims film phenomenon.Strike off thin film again, then little petechia occurs, claim petechial hemorrhage phenomenon.White Squama, shinny thin film and petechial hemorrhage are to diagnose psoriatic key character, and referred to as three levy.Homeliness type Psoriatic lesion is broadly divided into three periods from occurring to finally disappear: carry out phase, resting stage, regression Phase.
According to investigations, psoriasic sickness rate accounts for the 0.1%-3% of world population, and yellow's sickness rate is 0.1%-0.3%, this disease sickness rate white people in crowd are higher than yellow, and black race takes second place.Cause The obstinate refractory of this disease, is the most still listed in the important subject in department of dermatologry field, the world, is whole world skin One of skin section keypoint control disease.In the national psoriasis preventing and treating cooperation meeting held in recent years, participant Expert unanimously thinks that " traditional Chinese medical science is anti-antipsoriatic direction.Doctor trained in Western medicine anticarcinogen and hormone medicine have seriously Side effect, it should avoid use ".
Prior art has the medicine of multiple treatment tinea, has for oral administration, also have external, such as cortex Steroid hormone ointment.Potent steroid hormone class ointment external cleaning, instant effect, but drug withdrawal is easily recurred, Life-time service side effect increases, thus many doctors tendency need not, or only short-term, be interrupted use.
Summary of the invention
For above-mentioned weak point, it is an object of the invention to provide one and treat psoriasic Chinese medicinal ointment, This invention has heat-clearing and toxic substances removing, convergence granulation promoting, changes corruption hemostasis, effect of dispelling wind for relieving itching, to psoriasis, The dermatosiss such as eczema are evident in efficacy, have no side effect skin.
Technical scheme is summarized as follows: one treats psoriasic Chinese medicinal ointment, including following heavy The composition of amount part: Radix Stemonae extract 4~10 parts;Radix Sophorae Flavescentis extract 1~3 parts;Fructus Psoraleae extract 1~ 10 parts;Radix Pulsatillae extract 2~8 parts;Cortex Moutan extract 3~8 parts;Ethanol 3~8 parts;Radix Salviae Miltiorrhizae carries Take thing 0.5~3 parts;Poria extract 3~7 parts;Fructus Kochiae extract 3~15 parts;Radix Saposhnikoviae extract 1~3 part;Periostracum Cicadae extract 0.5~3 parts;Huai Goat 5~13 parts;Lauryl sulfosuccinate Monoesters disodium 2~8 parts.
Preferably, including the composition of following weight portion: Radix Stemonae extract 5~8 parts;Radix Sophorae Flavescentis extract 1~ 2 parts;Fructus Psoraleae extract 3~6 parts;Radix Pulsatillae extract 3~6 parts;Cortex Moutan extract 4~6 parts; Ethanol 4~7 parts;Radix Salviae Miltiorrhizae extract 1~2 parts;Poria extract 4~6 parts;Fructus Kochiae extract 4~ 8 parts;Radix Saposhnikoviae extract 1~3 parts;Periostracum Cicadae extract 1~2 parts;Huai Goat 7~10 parts;Month Osmanthus base sulfosuccinic acid monoester disodium 3~5 parts.
Preferably, including the composition of following weight portion: Radix Stemonae extract 6 parts;Radix Sophorae Flavescentis extract 1.5 Part;Fructus Psoraleae extract 4 parts;Radix Pulsatillae extract 6 parts;Cortex Moutan extract 5 parts;Ethanol 6 parts; Radix Salviae Miltiorrhizae extract 1.5 parts;Poria extract 5 parts;Fructus Kochiae extract 5 parts;Radix Saposhnikoviae extract 1.5 Part;Periostracum Cicadae extract 1.5 parts;Huai Goat 8 parts;Lauryl sulfosuccinic acid monoester disodium 4 parts.
Preferably, the Radix Glycyrrhizae extract of 2~5 parts is also included.
Another case of the present invention is to provide a kind of preparation method treating psoriasic Chinese medicinal ointment, bag Include following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, centrifugation after extraction, by filter vacuum thin film evaporation, obtains Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 1~4 hours, then be stirred hot dipping and carry, hot dipping is centrifugal after carrying, and collects supernatant, respectively By supernatant concentration, respectively obtain Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae carry Take thing, Periostracum Cicadae extract, Huai Goat;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
Preferably, in described step (1), Extracting temperature is 40~70 DEG C, and extraction time is 2~5h, material Liquid weight ratio is 1:4~1:10.
Preferably, hot-water soak 2h in described step (2), extraction temperature is 50~60 DEG C, during extraction Between be 3~5h, feed liquid weight ratio is 1:5~1:10.
The invention has the beneficial effects as follows: the invention belongs to Chinese medicine preparation, safe and reliable have no side effect, be The preferable external application Chinese medicine unguentum for the treatment of psoriasis, neurodermatitis etc., with reducing swelling and alleviating pain, promoting flow of QI and blood be The rule for the treatment of, the combination of multiple medical material is collaborative, is mainly used in removing damp-heat, cooling blood for hemostasis, liver heat removing and eyesight improving, draws out pus by applying a plaster to the affected part Relieve oedema or abdominal distension through diuresis or purgation, promoting blood flow to regulate menstruation, cold expelling are regulated the flow of vital energy, eliminating carbuncle eliminating stagnation, regulate internal organs negative and positive, and promoting flow of QI and blood, to Corii Bovis seu Bubali Tinea has significant therapeutic effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art join Book word can be implemented according to this as directed.
Embodiment 1
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 4 parts; Radix Sophorae Flavescentis extract 1 part;Fructus Psoraleae extract 1 part;Radix Pulsatillae extract 2 parts;Cortex Moutan extract 3 parts; Ethanol 3 parts;Radix Salviae Miltiorrhizae extract 0.5 part;Poria extract 3 parts;Fructus Kochiae extract 3 parts;Radix Saposhnikoviae Extract 1 part;Periostracum Cicadae extract 0.5 part;Huai Goat 5 parts;Lauryl sulfosuccinic acid monoester Disodium 2 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 40 DEG C, and extraction time is 2h, feed liquid weight Than being 1:4, centrifugation after extraction, by filter vacuum thin film evaporation, obtain Radix Stemonae extract, Radix Sophorae Flavescentis carries Take thing, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 1 hour, then be stirred hot dipping and carry, extraction temperature is 50 DEG C, and extraction time is 3h, material Liquid weight ratio is 1:5, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, the Flos Sophorae Immaturus Extract;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
Embodiment 2
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 10 parts; Radix Sophorae Flavescentis extract 3 parts;Fructus Psoraleae extract 10 parts;Radix Pulsatillae extract 8 parts;Cortex Moutan extract 8 parts; Ethanol 8 parts;Radix Salviae Miltiorrhizae extract 3 parts;Poria extract 7 parts;Fructus Kochiae extract 15 parts;Radix Saposhnikoviae carries Take thing 3 parts;Periostracum Cicadae extract 3 parts;Huai Goat 13 parts;Lauryl sulfosuccinic acid monoester disodium 8 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 70 DEG C, and extraction time is 5h, feed liquid weight Than being 1:4, centrifugation after extraction, by filter vacuum thin film evaporation, obtain Radix Stemonae extract, Radix Sophorae Flavescentis carries Take thing, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 1 hour, then be stirred hot dipping and carry, extraction temperature is 60 DEG C, and extraction time is 5h, Feed liquid weight ratio is 1:5, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively To Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, Chinese scholartree Rice extracts;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
Embodiment 3
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 8 parts; Radix Sophorae Flavescentis extract 2 parts;Fructus Psoraleae extract 6 parts;Radix Pulsatillae extract 6 parts;Cortex Moutan extract 6 parts; Ethanol 7 parts;Radix Salviae Miltiorrhizae extract 2 parts;Poria extract 6 parts;Fructus Kochiae extract 8 parts;Radix Saposhnikoviae carries Take thing 3 parts;Periostracum Cicadae extract 2 parts;Huai Goat 10 parts;Lauryl sulfosuccinic acid monoester disodium 5 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 50 DEG C, and extraction time is 4h, feed liquid weight Than being 1:9, centrifugation after extraction, by filter vacuum thin film evaporation, obtain Radix Stemonae extract, Radix Sophorae Flavescentis carries Take thing, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 1.5 hours, then be stirred hot dipping and carry, hot-water soak 2h, extraction temperature is 58 DEG C, leaching The time of carrying is 4.5h, and feed liquid weight ratio is centrifugal after 1:8 hot dipping carries, and collects supernatant, respectively by supernatant Liquid concentrate, respectively obtain Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, Huai Goat;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
Embodiment 4
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 5 parts; Radix Sophorae Flavescentis extract 1 part;Fructus Psoraleae extract 3 parts;Radix Pulsatillae extract 3 parts;Cortex Moutan extract 4 parts; Ethanol 4 parts;Radix Salviae Miltiorrhizae extract 1 part;Poria extract 4 parts;Fructus Kochiae extract 4 parts;Radix Saposhnikoviae carries Take thing 1 part;Periostracum Cicadae extract 1 part;Huai Goat 7 parts;Lauryl sulfosuccinic acid monoester disodium 3 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 45 DEG C, and extraction time is 5h, feed liquid weight Ratio is 1:10, centrifugation after extraction, by filter vacuum thin film evaporation, obtains Radix Stemonae extract, Radix Sophorae Flavescentis Extract, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces During hot-water soak 2, then being stirred hot dipping and carry, extraction temperature is 55, and extraction time is 5, feed liquid weight Amount ratio is 1:10, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively obtains pellet Conopsea extraction, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, the Flos Sophorae Immaturus carry Take thing;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
Embodiment 5
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 6 parts; Radix Sophorae Flavescentis extract 1.5 parts;Fructus Psoraleae extract 4 parts;Radix Pulsatillae extract 6 parts;Cortex Moutan extract 5 Part;Ethanol 6 parts;Radix Salviae Miltiorrhizae extract 1.5 parts;Poria extract 5 parts;Fructus Kochiae extract 5 parts; Radix Saposhnikoviae extract 1.5 parts;Periostracum Cicadae extract 1.5 parts;Huai Goat 8 parts;Lauryl sulfosuccinate Acid monoester disodium 4 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 45 DEG C, and extraction time is 3h, feed liquid weight Ratio is 1:7, centrifugation after extraction, by filter vacuum thin film evaporation, obtains Radix Stemonae extract, Radix Sophorae Flavescentis Extract, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 2.5 hours, then be stirred hot dipping and carry, extraction temperature is 58 DEG C, and extraction time is 3.5h, Feed liquid weight ratio is 1:8, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively To Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, Chinese scholartree Rice extracts;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
Embodiment 6
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 6 parts; Radix Sophorae Flavescentis extract 1.5 parts;Fructus Psoraleae extract 4 parts;Radix Pulsatillae extract 6 parts;Cortex Moutan extract 5 Part;Ethanol 6 parts;Radix Salviae Miltiorrhizae extract 1.5 parts;Poria extract 5 parts;Fructus Kochiae extract 5 parts; Radix Saposhnikoviae extract 1.5 parts;Periostracum Cicadae extract 1.5 parts;Huai Goat 8 parts;Lauryl sulfosuccinate Acid monoester disodium 4 parts, Radix Glycyrrhizae extract 2 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 70 DEG C, and extraction time is 5h, feed liquid weight Ratio is 1:10, centrifugation after extraction, by filter vacuum thin film evaporation, obtains Radix Stemonae extract, Radix Sophorae Flavescentis Extract, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 4 hours, then be stirred hot dipping and carry, extraction temperature is 60 DEG C, and extraction time is 5h, material Liquid weight ratio is 1:10, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively To Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, Chinese scholartree Rice extracts;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, Radix Glycyrrhizae carries Taking thing, by above-mentioned various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment Agent.
Embodiment 7
One treats psoriasic Chinese medicinal ointment, including the composition of following weight portion: Radix Stemonae extract 6 parts; Radix Sophorae Flavescentis extract 1.5 parts;Fructus Psoraleae extract 4 parts;Radix Pulsatillae extract 6 parts;Cortex Moutan extract 5 Part;Ethanol 6 parts;Radix Salviae Miltiorrhizae extract 1.5 parts;Poria extract 5 parts;Fructus Kochiae extract 5 parts; Radix Saposhnikoviae extract 1.5 parts;Periostracum Cicadae extract 1.5 parts;Huai Goat 8 parts;Lauryl sulfosuccinate Acid monoester disodium 4 parts, Radix Glycyrrhizae extract 5 parts.
Its preparation method containing following steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, and Extracting temperature is 40 DEG C, and extraction time is 2h, feed liquid weight Than being 1:4, centrifugation after extraction, by filter vacuum thin film evaporation, obtain Radix Stemonae extract, Radix Sophorae Flavescentis carries Take thing, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 2 hours, then be stirred hot dipping and carry, extraction temperature is 50 DEG C, and extraction time is 3.5h, Feed liquid weight ratio is 1:6, and hot dipping is centrifugal after carrying, and collects supernatant, respectively by supernatant concentration, respectively To Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae extract, Periostracum Cicadae extract, Chinese scholartree Rice extracts;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, Radix Glycyrrhizae carries Taking thing, by above-mentioned various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment Agent.
Although embodiment of the present invention are disclosed as above, but it is not restricted to description and embodiment party Listed utilization in formula, it can be applied to various applicable the field of the invention completely, for being familiar with ability For the personnel in territory, be easily achieved other amendment, therefore without departing substantially from claim and etc. homotype Enclosing under limited general concept, the present invention is not limited to specific details.

Claims (7)

1. treat psoriasic Chinese medicinal ointment for one kind, it is characterised in that include the composition of following weight portion: Radix Stemonae extract 4~10 parts;Radix Sophorae Flavescentis extract 1~3 parts;Fructus Psoraleae extract 1~10 parts;The Radix Pulsatillae Extract 2~8 parts;Cortex Moutan extract 3~8 parts;Ethanol 3~8 parts;Radix Salviae Miltiorrhizae extract 0.5~3 parts; Poria extract 3~7 parts;Fructus Kochiae extract 3~15 parts;Radix Saposhnikoviae extract 1~3 parts;Periostracum Cicadae carries Take thing 0.5~3 parts;Huai Goat 5~13 parts;Lauryl sulfosuccinic acid monoester disodium 2~8 parts.
2. the psoriasic Chinese medicinal ointment for the treatment of as claimed in claim 1, it is characterised in that include following The composition of weight portion: Radix Stemonae extract 5~8 parts;Radix Sophorae Flavescentis extract 1~2 parts;Fructus Psoraleae extract 3~ 6 parts;Radix Pulsatillae extract 3~6 parts;Cortex Moutan extract 4~6 parts;Ethanol 4~7 parts;Radix Salviae Miltiorrhizae extracts Thing 1~2 parts;Poria extract 4~6 parts;Fructus Kochiae extract 4~8 parts;Radix Saposhnikoviae extract 1~3 Part;Periostracum Cicadae extract 1~2 parts;Huai Goat 7~10 parts;Lauryl sulfosuccinic acid monoester disodium 3~5 parts.
3. the psoriasic Chinese medicinal ointment for the treatment of as claimed in claim 1, it is characterised in that include following The composition of weight portion: Radix Stemonae extract 6 parts;Radix Sophorae Flavescentis extract 1.5 parts;Fructus Psoraleae extract 4 parts; Radix Pulsatillae extract 6 parts;Cortex Moutan extract 5 parts;Ethanol 6 parts;Radix Salviae Miltiorrhizae extract 1.5 parts;Poria Extract 5 parts;Fructus Kochiae extract 5 parts;Radix Saposhnikoviae extract 1.5 parts;Periostracum Cicadae extract 1.5 parts; Huai Goat 8 parts;Lauryl sulfosuccinic acid monoester disodium 4 parts.
4. the psoriasic Chinese medicinal ointment for the treatment of as claimed in claim 1, it is characterised in that also include The Radix Glycyrrhizae extract of 2~5 parts.
5. the preparation method treating psoriasic Chinese medicinal ointment as claimed in claim 1, it is characterised in that Comprise the steps:
Step 1): take the Radix Stemonae, Radix Sophorae Flavescentis, Fructus Psoraleae, the Radix Pulsatillae, Cortex Moutan are smashed to pieces, are separately added into after smashing to pieces The ethanol water of 40wt% extracts, centrifugation after extraction, by filter vacuum thin film evaporation, obtains Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, Radix Pulsatillae extract and Cortex Moutan extract;
Step 2): take Radix Salviae Miltiorrhizae, Poria, the Fructus Kochiae, Radix Saposhnikoviae, Periostracum Cicadae, the Flos Sophorae Immaturus are smashed to pieces, add after smashing to pieces Hot-water soak 1~4 hours, then be stirred hot dipping and carry, hot dipping is centrifugal after carrying, and collects supernatant, respectively By supernatant concentration, respectively obtain Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae carry Take thing, Periostracum Cicadae extract, Huai Goat;
Step 3): take Radix Stemonae extract, Radix Sophorae Flavescentis extract, Fructus Psoraleae extract, the Radix Pulsatillae by weight Extract, Cortex Moutan extract, Radix Salviae Miltiorrhizae extract, Poria extract, Fructus Kochiae extract, Radix Saposhnikoviae are extracted Thing, Periostracum Cicadae extract, Huai Goat, ethanol and lauryl sulfosuccinic acid monoester disodium, by above-mentioned Various extracts and other adjuvant mix homogeneously, obtain medical treatment psoriasic Chinese medicinal ointment.
6. the preparation method treating psoriasic Chinese medicinal ointment as claimed in claim 5, it is characterised in that In described step (1), Extracting temperature is 40~70 DEG C, and extraction time is 2~5h, and feed liquid weight ratio is 1:4~1:10.
7. the preparation method treating psoriasic Chinese medicinal ointment as claimed in claim 5, it is characterised in that Hot-water soak 2h in described step (2), extraction temperature is 50~60 DEG C, and extraction time is 3~5h, material Liquid weight ratio is 1:5~1:10.
CN201610454239.5A 2016-06-21 2016-06-21 Traditional Chinese medicine ointment for treating psoriasis and preparation method thereof Pending CN105943983A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1839922A (en) * 2006-01-24 2006-10-04 河南辅仁药业集团有限公司 Traditional Chinese medicine preparation for treating leukoderma, psoriasis and its preparation method
CN104771666A (en) * 2015-04-26 2015-07-15 张昌莲 Traditional Chinese medicine composition for treating psoriasis
CN105477129A (en) * 2015-12-16 2016-04-13 王金国 External-use plaster for psoriasis and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1839922A (en) * 2006-01-24 2006-10-04 河南辅仁药业集团有限公司 Traditional Chinese medicine preparation for treating leukoderma, psoriasis and its preparation method
CN104771666A (en) * 2015-04-26 2015-07-15 张昌莲 Traditional Chinese medicine composition for treating psoriasis
CN105477129A (en) * 2015-12-16 2016-04-13 王金国 External-use plaster for psoriasis and preparation method thereof

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