CN105396025A - Traditional Chinese medicine analgesic paste for relieving cancer pain and effective ingredients and preparation method thereof - Google Patents

Traditional Chinese medicine analgesic paste for relieving cancer pain and effective ingredients and preparation method thereof Download PDF

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Publication number
CN105396025A
CN105396025A CN201511008428.1A CN201511008428A CN105396025A CN 105396025 A CN105396025 A CN 105396025A CN 201511008428 A CN201511008428 A CN 201511008428A CN 105396025 A CN105396025 A CN 105396025A
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parts
chinese medicine
pain
plaster
pain relieving
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龙洋
秦元梅
刘姝
费景兰
陈欣菊
权春分
林志红
杨艳明
李贞�
原利娟
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
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    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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Abstract

The invention provides traditional Chinese medicine analgesic paste for relieving cancer pain and effective ingredients and preparation method thereof and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine analgesic paste comprises the effective ingredients and honey, wherein the weight ratio of the effective ingredients to the honey is 8:25; the effective ingredients are composed of, by weight, 20 parts of olibanum, 20 parts of myrrh, 20 parts of nux vomica, 15 parts of rhizoma kaempferiae, 30 parts of rhizoma corydalis, 0.1 part of musk, 30 parts of artemisia anomala, 30 parts of radix paeoniae rubra, 30 parts of dandelion and 20 parts of indigo naturalis. The traditional Chinese medicine analgesic paste has the advantages that the effects of promoting blood circulation to remove blood stasis and relieving swelling and pain are achieved, and the paste is less in side effect, convenient to use, easy to obtain and remarkable in pain-killing effect.

Description

A kind of Chinese medicine pain relieving plaster, its effective ingredient and preparation method thereof for cancer pain
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine pain relieving plaster, its effective ingredient and preparation method thereof for cancer pain.
Background technology
Cancer pain is the common cardinal symptom of cancer patient, and according to World Health Organization's investigation statistics, the whole world has new cancer patient more than 1,000 ten thousand every year.At the early and middle portion that cancer is made a definite diagnosis, the patient of 30-45% has moderate to severe pain, and the whole world has at least 5,000,000 cancer patients to survive in the torment of pain every day.The existing cancer patient more than 200 ten thousand of China, have more than 1,000,000 to be in pain, 50% patient bears moderate to severe pain, and 35% is insufferable severe pain.Ministry of Public Health investigation display in 1997, cancer pain incidence rate is 61.6%.
At present, the many employings of pain relieving of cancers three grades of step analgesia methods, based on oral, drug side effect is large, gastrointestinal reaction weight.The pain relieving plaster of external generally needs doctor to open anesthesia prescription could to use.
Summary of the invention
The object of the invention is to disclose a kind of Chinese medicine pain relieving plaster for cancer pain.
Another object of the present invention is to disclose a kind of Chinese medicine pain relieving plaster effective ingredient for cancer pain.
3rd object of the present invention is the preparation method disclosing a kind of Chinese medicine pain relieving plaster for cancer pain.
The object of the invention is to be achieved through the following technical solutions:
A kind of Chinese medicine pain relieving plaster effective ingredient for cancer pain, wherein, described effective ingredient is made up of the crude drug of following weight portion: Olibanum 20 parts, Myrrha 20 parts, Semen Strychni 20 parts, Rhizoma Kaempferiae 15 parts, Rhizoma Corydalis 30 parts, 0.1 part, Moschus, Herba Artemisiae Anomalae 30 parts, Radix Paeoniae Rubra 30 parts, Herba Taraxaci 30 parts and Indigo Naturalis 20 parts.
For a Chinese medicine pain relieving plaster for cancer pain, comprise and applying ointment or plaster, wherein, described Chinese medicine pain relieving plaster also comprises effective ingredient and Mel, and the weight ratio wherein between effective ingredient and Mel is 8:25;
Described effective ingredient is made up of the crude drug of following weight portion: Olibanum 20 parts, Myrrha 20 parts, Semen Strychni 20 parts, Rhizoma Kaempferiae 15 parts, Rhizoma Corydalis 30 parts, 0.1 part, Moschus, Herba Artemisiae Anomalae 30 parts, Radix Paeoniae Rubra 30 parts, Herba Taraxaci 30 parts and Indigo Naturalis 20 parts.
For a preparation method for the Chinese medicine pain relieving plaster of cancer pain, comprise the following steps:
(1) crude drug of following weight portion, is taken: Olibanum 20 parts, Myrrha 20 parts, Semen Strychni 20 parts, Rhizoma Kaempferiae 15 parts, Rhizoma Corydalis 30 parts, 0.1 part, Moschus, Herba Artemisiae Anomalae 30 parts, Radix Paeoniae Rubra 30 parts, Herba Taraxaci 30 parts and Indigo Naturalis 20 parts;
(2), the crude drug that step (1) takes is put into pulverizer and shatter into smalls;
(3) add Mel in the Chinese medicine powder, toward step (2) obtained, be modulated into pasty state; Weight ratio wherein between Chinese medicine powder and Mel is 8:25;
(4), by the paste product of step (3) spread upon on applying ointment or plaster, obtain the Chinese medicine pain relieving plaster for cancer pain.
In effective ingredient of the present invention with Olibanum, Myrrha for monarch, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain; With Rhizoma Corydalis (also known as Rhizoma Corydalis), Rhizoma Kaempferiae, Moschus for minister, promoting flow of QI and blood, removing obstruction for relieving pain, Herba Taraxaci, Indigo Naturalis heat-clearing and toxic substances removing, removing obstruction for relieving pain; Help with Herba Artemisiae Anomalae, Radix Paeoniae Rubra promoting blood circulation to restore menstrual flow, relieving spasm to stop pain, Semen Strychni activating collaterals and eliminating stagnation, reducing swelling and alleviating pain.
The present invention has following beneficial effect:
1, a kind of Chinese medicine pain relieving plaster for cancer pain of the present invention and effective ingredient thereof have the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.
2, a kind of Chinese medicine pain relieving plaster for cancer pain of the present invention and effective ingredient few side effects thereof, easy to use, is easy to obtain, relieving pain.
3, a kind of Chinese medicine pain relieving plaster for cancer pain of the present invention does not have the constipation caused by oral pain alleviating medicine, the side effect such as additive, can life-time service.
Detailed description of the invention:
Being convenient to for making technical scheme of the present invention understand, below in conjunction with specific embodiment, a kind of Chinese medicine pain relieving plaster, its effective ingredient and preparation method thereof for cancer pain of the present invention being further described.
embodiment 1:a kind of Chinese medicine pain relieving plaster effective ingredient for cancer pain:
Take the crude drug of following weight portion: Olibanum 20g, Myrrha 20g, Semen Strychni 20g, Rhizoma Kaempferiae 15g, Rhizoma Corydalis (also known as Rhizoma Corydalis) 30g, Moschus 0.1g, Herba Artemisiae Anomalae 30g, Radix Paeoniae Rubra 30g, Herba Taraxaci 30g and Indigo Naturalis 20g, obtain the Chinese medicine pain relieving plaster effective ingredient for cancer pain.
embodiment 2:a kind of Chinese medicine pain relieving plaster for cancer pain:
(1) crude drug of following weight portion, is taken: Olibanum 20g, Myrrha 20g, Semen Strychni 20g, Rhizoma Kaempferiae 15g, Rhizoma Corydalis (also known as Rhizoma Corydalis) 30g, Moschus 0.1g, Herba Artemisiae Anomalae 30g, Radix Paeoniae Rubra 30g, Herba Taraxaci 30g and Indigo Naturalis 20g;
(2), the crude drug that step (1) takes is put into pulverizer and shatter into smalls;
(3) add Mel in the Chinese medicine powder, toward step (2) obtained, be modulated into pasty state; Weight ratio wherein between Chinese medicine powder and Mel is 8:25;
(4), by the paste product of step (3) spread upon on applying ointment or plaster, obtain the Chinese medicine pain relieving plaster for cancer pain.
In example 2, paste product spreads upon applying ointment or plaster in (the coating district that there are a 10cm × 7cm in central authorities) of a 16cm × 13cm, makes Chinese medicine pain relieving plaster.
Below by way of concrete test, the result of use that Chinese medicine pain relieving plaster of the present invention has is described:
test example 1:
Patient, man, 55 years old, primary hepatic carcinoma patients in advanced stage, cardinal symptom was hepatalgia, pain scores 5 points.
Give Chinese medicine pain relieving plaster to stick, alleviate after 50 minutes, pain scores 0 point.Pain relieving plaster retains 6 hours, 1 day 2 times, within 14 days, is a course for the treatment of.
test example 2:
Patient, female, 53 years old, primary hepatocarcinoma radio-frequency (RF) ablation was postoperative, and cardinal symptom is hepatalgia, scorching hot.Pain scores 4 points.
Give Chinese medicine pain relieving plaster to stick, alleviate after 1 hour, pain scores 0 point.Pain relieving plaster retains 6 hours, 1 day 1 time, within 14 days, is a course for the treatment of.Treatments period patient does not tell pain again.
test example 3:
Chinese medicine pain relieving plaster of the present invention is used for 210 routine liver cancer patients (pain relieving plaster is affixed on hepatic region), 64 routine patients with gastric cancer (pain relieving plaster is affixed on epigastrium), 23 routine colon cancer (pain relieving plaster being affixed on umbilicus week) and 19 routine Pancreas cancer patients (pain relieving plaster is affixed on midriff), shown in its clinical application effect statistical table table 1.
Table 1 Chinese medicine pain relieving plaster clinical application effect statistical table
Sick kind Case load Effectively Invalid Effective percentage
Hepatocarcinoma 210 192 18 91.43%
Gastric cancer 64 55 9 85.94%
Colon cancer 23 19 4 82.61%
Cancer of pancreas 19 14 5 73.68%
Amount to 316 280 36 88.61%
The above, be only preferred embodiment of the present invention, not any formal and substantial restriction is done to the present invention, all those skilled in the art, do not departing within the scope of technical solution of the present invention, when utilizing disclosed above technology contents, and a little change made, modify with differentiation equivalent variations, be Equivalent embodiments of the present invention; Meanwhile, all according to substantial technological of the present invention to the change of any equivalent variations that above embodiment is done, modify and differentiation, all still belong in the scope of technical scheme of the present invention.

Claims (3)

1. for a Chinese medicine pain relieving plaster effective ingredient for cancer pain, it is characterized in that: described effective ingredient is made up of the crude drug of following weight portion: Olibanum 20 parts, Myrrha 20 parts, Semen Strychni 20 parts, Rhizoma Kaempferiae 15 parts, Rhizoma Corydalis 30 parts, 0.1 part, Moschus, Herba Artemisiae Anomalae 30 parts, Radix Paeoniae Rubra 30 parts, Herba Taraxaci 30 parts and Indigo Naturalis 20 parts.
2. for a Chinese medicine pain relieving plaster for cancer pain, comprise and applying ointment or plaster, it is characterized in that, described Chinese medicine pain relieving plaster also comprises effective ingredient and Mel, and the weight ratio wherein between effective ingredient and Mel is 8:25;
Described effective ingredient is made up of the crude drug of following weight portion: Olibanum 20 parts, Myrrha 20 parts, Semen Strychni 20 parts, Rhizoma Kaempferiae 15 parts, Rhizoma Corydalis 30 parts, 0.1 part, Moschus, Herba Artemisiae Anomalae 30 parts, Radix Paeoniae Rubra 30 parts, Herba Taraxaci 30 parts and Indigo Naturalis 20 parts.
3., for a preparation method for the Chinese medicine pain relieving plaster of cancer pain, comprise the following steps:
(1) crude drug of following weight portion, is taken: Olibanum 20 parts, Myrrha 20 parts, Semen Strychni 20 parts, Rhizoma Kaempferiae 15 parts, Rhizoma Corydalis 30 parts, 0.1 part, Moschus, Herba Artemisiae Anomalae 30 parts, Radix Paeoniae Rubra 30 parts, Herba Taraxaci 30 parts and Indigo Naturalis 20 parts;
(2), the crude drug that step (1) takes is put into pulverizer and shatter into smalls;
(3) add Mel in the Chinese medicine powder, toward step (2) obtained, be modulated into pasty state; Weight ratio wherein between Chinese medicine powder and Mel is 8:25;
(4), by the paste product of step (3) spread upon on applying ointment or plaster, obtain the Chinese medicine pain relieving plaster for cancer pain.
CN201511008428.1A 2015-12-29 2015-12-29 Traditional Chinese medicine analgesic paste for relieving cancer pain and effective ingredients and preparation method thereof Pending CN105396025A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109010697A (en) * 2018-10-08 2018-12-18 江苏霍氏医药科技有限公司 A kind of traditional Chinese medicine for outer use and preparation method thereof for treating cancer advanced stage pain
CN113332402A (en) * 2021-03-12 2021-09-03 聂明明 Cancer pain relieving plaster and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1124651A (en) * 1995-02-21 1996-06-19 高锡平 Prescription for external use medicine for curing many kinds of diseases
CN1502343A (en) * 2002-11-21 2004-06-09 余世春 Pain-eliminating anti-cancer traditional Chinese medicine and preparation process thereof
CN102688306A (en) * 2012-06-15 2012-09-26 河南中医学院 Ointment for treating acute pancreatitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1124651A (en) * 1995-02-21 1996-06-19 高锡平 Prescription for external use medicine for curing many kinds of diseases
CN1502343A (en) * 2002-11-21 2004-06-09 余世春 Pain-eliminating anti-cancer traditional Chinese medicine and preparation process thereof
CN102688306A (en) * 2012-06-15 2012-09-26 河南中医学院 Ointment for treating acute pancreatitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈其原: "消肿痛贴的制备及临床运用", 《四川中医》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109010697A (en) * 2018-10-08 2018-12-18 江苏霍氏医药科技有限公司 A kind of traditional Chinese medicine for outer use and preparation method thereof for treating cancer advanced stage pain
CN113332402A (en) * 2021-03-12 2021-09-03 聂明明 Cancer pain relieving plaster and preparation method thereof

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Inventor after: Long Yang

Inventor after: Li Zhen

Inventor after: Yuan Lijuan

Inventor after: Zhou Shifan

Inventor after: Qin Yuanmei

Inventor after: Liu Shu

Inventor after: Fei Jinglan

Inventor after: Chen Xinju

Inventor after: Quan Chunfen

Inventor after: Lin Zhihong

Inventor after: Yang Yanming

Inventor before: Long Yang

Inventor before: Yuan Lijuan

Inventor before: Qin Yuanmei

Inventor before: Liu Shu

Inventor before: Fei Jinglan

Inventor before: Chen Xinju

Inventor before: Quan Chunfen

Inventor before: Lin Zhihong

Inventor before: Yang Yanming

Inventor before: Li Zhen

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Application publication date: 20160316

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