CN105943840A - Health care product for reducing blood glucose and reducing fat - Google Patents

Abstract

The invention provides a health care product for reducing blood glucose and reducing fat, in particular the health care product. The health care product consists of the following raw materials or extracts of the following raw materials: sky fruits, glossy privet fruits, radix achyranthis bidentatae, radix asparagi, fructus corni, rhizoma polygonati odorati, poria cocos, fructus rubi, fruits of Chinese wolfberry and fiveleaf gynostemma herb, and the parts by weight of the raw materials are as follows: 8-12 parts of the sky fruits, 1-5 parts of the glossy privet fruits, 2-8 parts of the radix achyranthis bidentatae, 3-7 parts of the radix asparagi, 1-5 parts of the fructus corni, 1-3 parts of the rhizoma polygonati odorati, 1-5 parts of the poria cocos, 1-5 parts of the fructus rubi, 1-5 parts of the fruits of Chinese wolfberry and 1-5 parts of the fiveleaf gynostemma herb. The health care product disclosed by the invention is capable of obviously reducing blood glucose and reducing fat.

Description

A kind of health product of blood sugar lowering fat reducing

Technical field

The present invention relates to technical field of health care food, in particular it relates to the health product of a kind of blood sugar lowering fat reducing.

Background technology

In recent years, along with China's rapid development of economy, also there is huge change in the life style of our people Change.The pollution of environment, the change of dietary structure and bad life habits are all promoting China's hyperlipidemia and high blood The sickness rate rapid increase of sugar disease, and the trend of rejuvenation of falling ill is obvious.Hyperlipidemia is drawn with hyperglycemia The complications that rises, sequela harm be not only personal health, and inevitably injure and get home Front yard happiness and social stability.Clinical reality warns us: hyperlipidemia and hyperglycemia situation occurred frequently have become as me The public health problem that state is great, is that another serious harm people after cardiovascular and cerebrovascular disease, tumor are good for The Chronic Non-Communicable Diseases of health.

Hyperlipemia is mutually promoted with hyperglycemia, a lot of diabetes patients all with hyperlipemia, therefore people Generally diabetes and hyperlipemia are called sister sick, and think that hyperlipidemia is the secondary disease of diabetes.According to system The diabetic of meter about 40% has disorders of lipid metabolism.It is characterized in that triglyceride increases and high density lipoprotein level White reduction.When the reason that diabetes cause blood fat to increase is due to diabetes patient's insufficient insulin, internal lipase Activity is to lower, and therefore easily blood fat increases.On the other hand diabetes itself are same in addition to carbohydrate metabolism disturbance Time also accompany fat, protein and water, dielectric disorder.Free fatty is often had to mobilize from fat depot Out, triglyceride and FFA concentrations in blood is made to increase.

Health product for hyperlipidemia, hyperglycemic patients are a lot of in the market, but many health product effects Inconspicuous, also derive many side effect.

Therefore, this area has good blood sugar lowering fat reducing effect and side effect is little in the urgent need to exploitation is a kind of Health product.

Summary of the invention

It is an object of the invention to provide and a kind of there are good blood sugar lowering fat reducing effect and the little health product of side effect.

First aspect present invention provides a kind of health product, and described health product contain the extract of raw material or raw material, Wherein said raw material includes, wherein said raw material includes: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, mountain Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli,

Further, the weight portion of described raw material is as follows:

To sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part, Radix Asparagi 3-7 part, Fructus Corni 1-5 Part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part.

In another preference, the weight portion of described raw material is as follows:

To sky fruit 9-11 part, Fructus Ligustri Lucidi 1-3 part, Radix Achyranthis Bidentatae 3-6 part, Radix Asparagi 4-7 part, Fructus Corni 1-3 Part, Rhizoma Polygonati Odorati 1-2 part, Poria 2-4 part, Fructus Rubi 1-2.5 part, Fructus Lycii 1-3 part, Herb Gynostemmae Pentaphylli 2-4 part.

In another preference, the weight portion of described raw material is as follows:

To sky fruit 10 parts, Fructus Ligustri Lucidi 2 parts, Radix Achyranthis Bidentatae 5 parts, Radix Asparagi 6 parts, Fructus Corni 2 parts, Rhizoma Polygonati Odorati 1 Part, 3 parts of Poria, Fructus Rubi 2 parts, Fructus Lycii 2 parts, Herb Gynostemmae Pentaphylli 3 parts.

In another preference, described raw material by Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli composition.

In another preference, described health product are capsule preparations, and specification is 0.5g/ capsule.

In another preference, described extract includes: water extract, alcohol extraction thing or aqueous extract.

In another preference, described alcohol extraction thing includes ethanol extraction.

In another preference, described aqueous extract is with the extract of aqueous solvent extraction.

In another preference, described aqueous solvent refers to by water and solvent compatible with water (such as alcohol, including ethanol) The mixed solvent constituted, wherein water content is 10-99.5wt%, preferably 50-90wt%.

Second aspect present invention provides the combination of a kind of raw material, described combination include following raw material: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli, and, The weight portion of described raw material is as follows:

To sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part, Radix Asparagi 3-7 part, Fructus Corni 1-5 Part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part.

In another preference, the weight portion of described raw material is as follows:

To sky fruit 9-11 part, Fructus Ligustri Lucidi 1-3 part, Radix Achyranthis Bidentatae 3-6 part, Radix Asparagi 4-7 part, Fructus Corni 1-3 Part, Rhizoma Polygonati Odorati 1-2 part, Poria 2-4 part, Fructus Rubi 1-2.5 part, Fructus Lycii 1-3 part, Herb Gynostemmae Pentaphylli 2-4 part.

In another preference, the weight portion of described raw material is as follows:

To sky fruit 10 parts, Fructus Ligustri Lucidi 2 parts, Radix Achyranthis Bidentatae 5 parts, Radix Asparagi 6 parts, Fructus Corni 2 parts, Rhizoma Polygonati Odorati 1 Part, 3 parts of Poria, Fructus Rubi 2 parts, Fructus Lycii 2 parts, Herb Gynostemmae Pentaphylli 3 parts.

Third aspect present invention provides the purposes of the combination of the raw material described in second aspect present invention, is used for making Make preparation for dropping the health product of hypoglycemia and blood fat.

In another preference, the amount of application of described health product is that 2-8 agent for each person every day is (it is preferred that 3-5 Agent, more preferably, 4 doses), the application dosage of every day is equivalent to 4-8 gram of dry total raw material, is preferably equivalent to 4.5-7.0 gram dry total raw material.

Fourth aspect present invention provides the preparation method of a kind of health product, said method comprising the steps of:

(a) provide raw material, described raw material includes: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli,

Further, the weight portion of described raw material is as follows: to sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part, Radix Asparagi 3-7 part, Fructus Corni 1-5 part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 Part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part；

B () provides extract I and extract II；

(c) mixed extract I and extract II, thus prepare described health product.

In another preference, in step (b), include for preparing the raw material of extract I: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, the weight portion of described raw material is as follows: to sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part.

In another preference, in step (b), include for preparing the raw material of extract II: Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli, the weight portion of described raw material is as follows: Tianmen Winter 3-7 part, Fructus Corni 1-5 part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 part, Fructus Lycii 1-5 Part, Herb Gynostemmae Pentaphylli 1-5 part.

In another preference, in step (b), the preparation of described extract I includes step:

I () is passed through for the raw material preparing extract I and is pulverized, add alcoholic solution and extract, obtain alcohol extract；

(ii) above-mentioned alcohol extract is concentrated, obtain alcohol extraction concentrated solution, be dried, thus obtain described extract I.

In another preference, in step (i), described alcoholic solution includes ethanol solution.

In another preference, in step (i), the amount of the alcoholic solution of addition is the 2-20 of raw material gross mass Times, it is preferred that 3-15 times, more preferably, 3-10 times.

In another preference, in step (i), the mass fraction of described alcoholic solution is 10-90%, preferably Ground, 20-80%, more preferably, 30-70%, more preferably, 55-65%.

In another preference, in step (i), described in be extracted as reflux, extract, described reflux, extract, Time is 0.1h-8h, it is preferred that 0.2h-5h, more preferably, 0.5h-2h.

In another preference, in step (i), extract 3 times with alcoholic solution.

In another preference, the addition of the alcoholic solution that described extraction is 3 times can be identical, can be different.

In another preference, the addition of the alcoholic solution that described extraction is 3 times is different, and the alcohol every time extracted is molten Liquid addition is respectively 5-15 times of raw material gross mass, 3-10 times and 1-5 times.

In another preference, the time that described extraction is 3 times can be identical, it is also possible to different.

In another preference, the time that described extraction is 3 times is different, and the time every time extracted is respectively 0.5-2h, 0.5-1h, and 20-30min.

In another preference, in step (ii), described concentration includes decompression and/or is concentrated in vacuo.

In another preference, in step (ii), described in the temperature that is concentrated in vacuo be 20-120 DEG C, preferably Ground, 40-100 DEG C, more preferably, 50-70 DEG C.

In another preference, in step (ii), described vacuum is-1-0Mpa, it is preferred that -0.5-0Mpa, more preferably ,-0.1Mpa.

In another preference, in step (ii), described being dried includes vacuum drying.

In another preference, in step (ii), described vacuum drying temperature is 10-200 DEG C, preferably Ground, 20-150 DEG C, more preferably, 40-80 DEG C.

In another preference, in step (ii), described drying time is 2-30h, it is preferred that 5-28h , more preferably, 12-24h.

In another preference, dried moisture is less than 15%.

In another preference, in step (b), the preparation of described extract II includes step:

I the raw material being used for preparing extract II is added extraction in aqueous solution by (), obtain Aqueous extracts；

(ii) above-mentioned Aqueous extracts is concentrated, obtain water extracting liquid (thick extractum), be dried, thus carry described in obtaining Take thing II.

In another preference, in step (i), described aqueous solution is water.

In another preference, in step (i), the amount of the aqueous solution of addition is the 2-20 of raw material gross mass Times, it is preferred that 3-15 times, more preferably, 4-10 times.

In another preference, in step (i), by extraction with aqueous solution 3 times.

In another preference, the addition of the aqueous solution that described extraction is 3 times can be identical, can be different.

In another preference, the addition of the aqueous solution that described extraction is 3 times is different, and that extracts is water-soluble every time Liquid addition is respectively 5-10 times of raw material gross mass, 3-8 times and 1-4 times.

In another preference, the time that described extraction is 3 times is identical, for 0.1h-8h, it is preferred that 0.2h-5h, More preferably, 0.5h-3h.

In another preference, the time that described extraction is 3 times is different, and the time every time extracted is respectively 0.5-3h, 0.5-2h, and 0.5-1h.

In another preference, in step (i), before described extraction, also include extracting preparation The raw material of thing II soaks the step of 0.5-1h in described aqueous solution.

In another preference, in step (ii), described concentration includes decompression and/or is concentrated in vacuo.

In another preference, in step (ii), described in the temperature that is concentrated in vacuo be 20-120 DEG C, preferably Ground, 40-100 DEG C, more preferably, 60-80 DEG C.

In another preference, in step (ii), described vacuum is-1-0Mpa, it is preferred that -0.5-0Mpa, more preferably ,-0.1Mpa.

In another preference, in step (ii), described being dried includes vacuum drying.

In another preference, in step (ii), described vacuum drying temperature is 10-200 DEG C, preferably Ground, 40-150 DEG C, more preferably, 40-80 DEG C.

In another preference, in step (ii), described drying time is 2-30h, it is preferred that 5-28h, More preferably, 12-24h.

In another preference, dried moisture is less than 15%.

In another preference, concentrated solution (thick extractum) density obtained after described concentration is 1.1-4, preferably Ground, 1.2-2, more preferably, 1.24-1.35.

In another preference, in step (c), including step:

I () extract I, extract II mix, pulverize, sieve, obtain extract powder I and extract powder II respectively；

(ii) by extract powder I and extract powder II according to the ratio mix homogeneously of 2:1, and with pharmaceutically can connect The carrier being subject to mixes, packaging, thus obtains described health product.

In another preference, in described step (i), after described extract I and extract II co-grinding, Cross 60 mesh sieves.

In another preference, described pharmaceutically acceptable carrier is selected from lower group: microcrystalline Cellulose, lactose, Magnesium stearate, silicon dioxide, cross-linking sodium carboxymethyl cellulose, hydroxy-methyl cellulose, corn starch, friendship Connection cellulose, polyoxyethylene sorbitan monoleate or a combination thereof.

In should be understood that within the scope of the present invention, above-mentioned each technical characteristic of the present invention and below (as implemented Example) in can be combined with each other between each technical characteristic of specifically describing, thus constitute new or preferred skill Art scheme.As space is limited, the most tired at this state.

Detailed description of the invention

The present inventor, through long-term extensively in-depth study, by a large amount of screenings and test, develops first A kind of health product with notable blood sugar lowering fat reducing effect, this product has natural, safety and good taste, can have Effect improves the symptom of hyperglycemia, hyperlipidemia.Complete the present invention on this basis.

Raw material components

Xiang Tianguo: belonging to Meliaceae plant, it is the cleanest that the South Pacific Ocean is originated in source, contaminated minimum Saloman group Island, wherein minimum to sky fruit yield on you of Rana, more precious.To sky, fruit is cool in nature, antipyretic, convergence, Without any side effects, for the rareest a kind of plant.Described in " Malaysia's medical herbs catalogue ", its taste Bitter, puckery, cool in nature, antipyretic, convergence, kernel strong.Its seed has the effect such as blood sugar lowering, blood fat reducing, main Being used for treating the diseases such as diabetes, hyperlipidemia, endocrine disturbance, long-term taking has and improves physical function, carries High body immune function, strengthening healthy qi, activating cell, pre-anti-aging, slow down aging are the most useful to human body Place.

Fructus Ligustri Lucidi: be the Chinese medicine of replenishing kidney-YIN, nourishing the liver to improve visual acuity simply, sweet-bitter flavor, cool in nature, return Liver and kidney warp, There is nourishing the liver and kidney, merit that tonifying YIN nourishes blood.Modern medicine study proves, Fructus Ligustri Lucidi includes ursolic acid, manna Alcohol, glucose, fatty oil etc., have heart tonifying, diuresis and hepatoprotective effect, can make the leukocyte caused because of chemotherapy Decline quantity to raise, and staphylococcus aureus, escherichia coli are had inhibitory action.

Radix Achyranthis Bidentatae: root is used as medicine, raw use, promoting blood circulation to restore menstrual flow；Ripe use, invigorating the liver and kidney, strong waist knee joint；Control soreness of waist and knee joint, Caused by liver and kidney deficiency.Nature and flavor: bitter, sweet, sour are flat.Return liver, kidney channel.There is eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, by force Muscles and bones, inducing diuresis for treating stranguria syndrome, effect of conducting blood to flow downwards.

Radix Asparagi: tuber is conventional Chinese medicine, has nourshing Yin and drynsessmoistening prescription, to relieve inflammation or internal heat cough-relieving effect.Bitter in the mouth, flat, property Cold, sweet and slightly bitter taste.Enter lung, kidney channel.Radix Asparagi root tuber extract, containing chemical compositions such as steroid saponins, has Slow down aging, blood sugar lowering, antibacterial, the effect of antitumor, relieving cough and expelling phlegm.

Fructus Corni: for the drying and ripening sarcocarp of dicotyledon medicine Cornaceae plant Fructus Corni.Liver and kidney tonifying, Arresting seminal emission reducing urination, consolidating channel for hemostasis, arresting sweating takes off admittedly." sour in the mouth is put down to mention it in " herbal classic "." " medicine Justice " in mention it and " enter liver, the heart, kidney three warp.Fruit containing cornin, Saponin, tannin, ursolic acid, The chemical compositions such as gallic acid, malic acid, tartaric acid and vitamin A.

Rhizoma Polygonati Odorati: " herbal classic ": part of being used as medicine for the rhizome of liliaceous plant Rhizoma Polygonati Odorati, its sweet in the mouth, flat, enter lung, Stomach warp.Have yin nourishing, moisturize, heat clearing away, promote the production of body fluid, the effect such as cough-relieving.As tonic, cure mainly calentura The diseases such as impairment of YIN, deficiency-heat cough caused by dryness, heart disease, diabetes, tuberculosis, and high-grade nourishing food, delicacies can be made And beverage, with health role, it is worth vast farmers plantation.From Rhizoma Polygonati Odorati, extract flavonoid substances there is fall Blood glucose, blood fat, blood pressure etc. act on.

Poria: for the dry sclerotia of On Polyporaceae Poria, sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, Kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.Mentioning in Compendium of Material Medica, Poria abnormal smells from the patient is light and oozes, its property Up, born fluid, loosing the interspaces of skin and muscles, grow water source and decline, diuresis, therefore Zhang Jiegu calls its genus sun, floats and rises, Say its property also；Dong Yuan call its for the YIN aspect of YANG, fall and under, Yan Qigong is also.Mentioning in " book on Chinese herbal medicine is just " can profit Key dries, the then happy Fructus Alpiniae Oxyphyllae of profit key, leads turbid promoting the production of body fluid；Dry, dry spleen of relieving oedema or abdominal distension through diuresis or purgation, invigorating middle warmer stomach invigorating；Infantile convulsion, Thick intestines and internal organs of the body, control expectorant originally, help the fall of medicine.Have with its taste micro-sweet, therefore say YANG invigorating.But mend few benefit.

Fructus Rubi: for the dry fruit of rosaceous plant rubus chingii Hu.Nature and flavor: sweet in the mouth, acid, warm in nature. Gui Jing: return liver, kidney, bladder warp.There is supplementing the kidney to control the nocturnal reducing urination, effect of nourishing the liver to improve visual acuity." explaining abstruseness of the canon of materia medica " In mention, " Fructus Rubi, sweet puts down into kidney, plays a sun and controls flaccidity, and controlling nocturnal emission with astringent drugs is taken the photograph excessive, and kidney tonifying without scorching partially, Gu Smart and the most puckery evil, the product of gold and jade are also.

Fructus Lycii: for Chinese crude drug, sweet in the mouth, property is put down.Function tonification Liver and kidney, replenishing vital essence to improve eyesight." book on Chinese herbal medicine converges and says " State Fructus Lycii: " the kind mesh of controlling of custom cloud Fructus Lycii, non-controls mesh also, can strengthen lean god, and god is full the most smart sufficient, therefore controls mesh Effectively.Hardly realizing that Fructus Lycii can make gas to fill, blood can be mended, Yang Kesheng, and the moon can be grown, and fire can drop, and rheumatism can be gone, Here there is perfect magical effect ".Modern pharmacology proves that Fructus Lycii has the effects such as hepatoprotective blood fat reducing.

Herb Gynostemmae Pentaphylli: for the herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli.Bitter in the mouth；Micro-sweet；Cool in nature.Return lung；Spleen；Kidney Warp.The main active ingredient of Herb Gynostemmae Pentaphylli be gypenoside, Herb Gynostemmae Pentaphylli glucoside (polysaccharide), water-soluble amino acid, Flavonoid, multivitamin, trace element, mineral etc..To boil water with Herb Gynostemmae Pentaphylli or brew up, can treat Hypertension, hyperlipidemia, hyperglycemia, the disease such as fatty liver.There are protecting liver and detoxication, lowering blood pressure and blood fat blood glucose Effect.

Main advantages of the present invention include:

(1) traditional Chinese medical science think hyperglycemia, hyperlipidemia with deficiency and excess cause a disease, void person based on internal injury, have because of deficiency of qi and blood, Kidney channel is not enough, brains lose foster caused；Reality person is with deficiency in origin and excess in superficiality for suffering from, and the spleen kidney lung heart all can cause a disease.Diet, Seven emotions, overstrain, six climate exopathogens, heredity etc. can be all inducement.Wherein, the hyperglycemia traditional Chinese medical science i.e. " diabetes ", is reported Compose deficiency, eating and drinking without temperance, disorder of emotion, labor are intended to the reason such as excessive and all may result in and quench one's thirst.Pathological changes internal organs are main At lung, spleen, kidney, pathogenesis is mainly in YIN fluid deficiency, scorching inclined victory, and with the deficiency of YIN for this, scorching is mark, Both results each other.Lung dryness of the stomach heat, deficiency of both QI and YIN, deficiency of kidney-YIN, negative and positive two are mainly had the symptom such as to lose.Adjust Reason principle is nourishing yin and warming yang, the kidney invigorating fixation, clearing heat and moistening dryness, YIN nourishing and the production of body fluid promoting.Hyperlipemia in theory of Chinese medical science The cause of disease includes: intemperance of taking food, addiction delicious food savoury, dyspepsia gastrointestinal, and temper is stranded, and the clearing heat in QI system of spleen can not be changed Turbid, cause the turbid arteries and veins of being detained of expectorant to be sent out for primary disease；Love ease and hate work, enjoy a high position and live in ease and comfort, stagnation of QI-blood, hypoactivity of spleen-YANG, Dysfunction of the spleen in transportation and transformation, causes the obstacle that cream fat generates and converts；Feelings will is not smooth, and seven emotions are caused a disease, the interior invading five ZANG-organs, then Gas, blood, Tianjin, liquid dysfunction of the spleen in transportation and transformation, the cause defeated cloth of cream fat, transporting obstacle form hyperlipemia；Natural endowment is not Foot, or old deficiency of kidney-essence, the main water of kidney, then body fluid Metabolic disorder of suffering from a deficiency of the kidney, cause cream fat transit barrier.Primary disease Generation dirty with liver,spleen,kidney three in close relations, the dirty functional disorder of liver,spleen,kidney three is this.The traditional Chinese medical science is nursed one's health Stress depressed liver-energy dispersing and function of gallbladder promoting, Qinghua is damp and hot is main.

(2) using antipyretic, convergence according to the above theoretical present invention, to improving hyperglycemia, hyperlipidemia has special merit The Xiang Tianguo of effect is major function raw material.

(3) from nursing one's health, liver,spleen,kidney three is dirty starts with, and coordinates its liver controlling conveyance and dispersion with Fructus Corni, Radix Achyranthis Bidentatae, Fructus Lycii, QI movement being in harmonious way contributes to transporting and the lucid yang sending up of spleen；Damp and hot with Rhizoma Polygonati Odorati, Herb Gynostemmae Pentaphylli, Poria soothing liver and strengthening spleen, Qinghua Coordinating the transporting of spleen, the lucid yang sending up contributes to again the catharsis liter of liver and sends out；Liver spleen is in harmonious proportion, the transporting of essence of water and grain, defeated Cloth is normal, then phlegm-damp is difficult raw, and sick peace is always；Its kidney controlling essence storage is coordinated, for elder generation with Radix Asparagi, Fructus Ligustri Lucidi It this, the strong fortune of spleen, metaplasia is precise and tiny, must be by means of the warm of kidney yang and the nourishing of kidney yin；And essence in kidney Gas also depends on the cultivation of the essence of water and grain day after tomorrow and supplements nutrition, and could constantly fill and ripe.The liver and the kidney have a common source, liver Blood is kidney essense institute metaplasia, and the moon of fainting must treat that the essence foot of few the moon can be inflated smooth by blood, free flow of qi.

(4) capsule preparations of the present invention, is convenient for carrying and preserves.

Below in conjunction with specific embodiment, the present invention is expanded on further.Should be understood that these embodiments are only used for The bright present invention rather than restriction the scope of the present invention.The experiment side of unreceipted actual conditions in the following example Method, generally according to normal condition, or according to the condition proposed by manufacturer.Unless otherwise indicated, otherwise Percentage ratio and number are percentage by weight and parts by weight.

Embodiment 1

The preparation of described health product

(1) orientation sky fruit 120g, Fructus Ligustri Lucidi 210g, Radix Achyranthis Bidentatae 500g are mixed, pulverize as mixed after coarse grain Close, obtain mixture A；By ethanol solution reflux, extract, 3 times, the addition of ethanol solution is respectively mixture 10 times of A gross mass, 7 times and 3 times, reflux extracting time is respectively 2 hours, 1 hour and 30 minutes, The mass fraction of ethanol solution is 65%；The alcohol extract of gained 50～70 DEG C temperature is concentrated in vacuo, with And under the vacuum of-0.1Mpa, concentrated by decompression or vacuum, thus obtain alcohol extraction concentrated solution；It After, at a temperature of the vacuum drying of 40～80 DEG C, under the vacuum of-0.1Mpa, alcohol extraction concentrated solution is done Dry 24h, it is thus achieved that the dry extract (i.e. extract I) of moisture less than 20%.

(2) medicinal residues after alcohol extraction add in step (1) Radix Asparagi 630g, Fructus Corni 210g, Rhizoma Polygonati Odorati 95g, Poria 280g, Fructus Rubi 220g, Fructus Lycii 210g, Herb Gynostemmae Pentaphylli 270g, obtain mixture B, to mixing Thing B water carries 3 times, and the amount of water that three water carries is respectively 10 times of mixture B gross mass, 8 times and 4 Times, carrying out for the first time water in advance mixture B is soaked in advance 1 hour, the time that 3 water carries is respectively 3 hours, 2 hours and 1 hour；Last Aqueous extracts the temperature being concentrated in vacuo of 60～80 DEG C, Under the vacuum of-0.1Mpa, by reducing pressure or being concentrated in vacuo to thick extractum, the density of the thick extractum of gained is 1.35, afterwards at a temperature of the vacuum drying of 60～80 DEG C, under the vacuum of-0.1Mpa, thick extractum is done Dry 24 hours, obtain dry extract (i.e. extract II).

(3) powder process: the extract II that extract I step (1) obtained and step (2) obtain, pulverizes, Cross 60 mesh sieves, obtain extract powder, according to part by weight 2:1 mix homogeneously, be capsule filling；

(4) finished product is made: after the capsule filling that step (3) obtains being mixed with excipient substance microcrystalline Cellulose Load capsule, packaging, obtain health product of the present invention (capsule).

Embodiment 2

Give 20 respectively by obtained sample (capsule of embodiment 1) and hyperglycemia occurs and with high blood The patient of fat symptom takes, and twice daily, each 1g, after taking 30 days, 20 patients have and substantially change Kind sensation, effect is satisfactory.

Embodiment 3

Zhang, women, 75 years old, dizziness occurred after fatigue before 2 years, accompanies distending pain in the head, top-heavy sense, companion Feeling sick without vomiting, accompany tinnitus, ignore thing and rotate, after rest, symptom is without substantially alleviating, then to hospital admission. Being diagnosed as type ii diabetes and hyperlipemia, be once interrupted drug administration hypoglycemic, existing non-rule is taken medicine, Blood fat, poor blood glucose control.Take the capsule of embodiment 1, twice daily, each 1g, take 30 days After, the state of an illness is obviously improved, and effect is satisfactory.

Embodiment 4

Liu, 38 years old, male, due to long-term diet outside, drinks uncontrolled, lacks motion, cause Body weight 188 jin, the too high impaired glucose tolerance of long-term blood glucose value, it is diagnosed as hyperlipidemia and type ii diabetes, Control the state of an illness after drug administration hypoglycemic, but Long-term taking medicine bring to life constant, several times make great efforts fat-reducing, But all end in failure.Take the capsule of embodiment 1, twice daily, each 1g, after taking 20 days, Blood pressure and blood lipoid is stable, allow people pleasantly surprised be that body weight has cut 5 jin, effect is satisfactory.

Embodiment 5

High certain, man, 59 years old, in health check-up, find that fasting glucose is 1.4mmol/L the year before；Serum glycerol Three fat are 6.38mmol/L；Serum low-density LP is 0.73mmol/L；Glucose in urine is ++++, often have Cardiopalmus, nervous symptom；Hospital is diagnosed as hyperglycemia hypertension, hyperlipemia three-hypers and deposits, with heart disease, often See weak, dynamic then from dropping sweat, breathe hard, poor appetite.Look into pale and tender tongue, white and thin fur, while there is indentation, deep pulse The most unable, seek the tens of families of doctor, although every huge is taken medicine, but blood glucose blood pressure is the most up and down, extremely unstable Fixed, patient heart is the most dejected.Take the capsule of embodiment 1, twice daily, each 1g, take 45 After it, checking in hospital, blood fat tends to normal, and blood pressure is steady, and post-prandial glycemia is 7.2mmol/L. spirit Looks have greatly change, and nervous, cardiopalmus symptom is completely eliminated, and sleep, complexion take a favorable turn, and effect makes us full Meaning.

Embodiment 6

Jiang, 53 years old, suffers from diabetes more than ten years, type ii diabetes, with high blood ester, and visual deterioration, Lumbago, dizzy, fatigue and weak, excessive thirst, numb limbs and tense tendons, skin pruritus.Take the capsule of embodiment 1, Twice daily, each 1g, after taking 30 days, blood glucose starts to decline steadily, and tired phenomenon substantially alleviates, Effect is satisfactory.

Embodiment 7

Wang, 46 years old, suffers from type Ⅱdiabetes mellitus 5 years, retinopathy, retinal hemorrhage, with hyperlipidemia, Coronary heart disease, nephropathy, anasarca, fasting glucose 25 mMs rises, glucose in urine ++++, take various Chinese and Western Medicine poor effect, the state of an illness increases the weight of the most day by day, after have no alternative but to use instead long term injections insulin and maintain, take enforcement The capsule of example 1, twice daily, each 1g, after taking 30 days, blood glucose starts to decline steadily, and vision is extensive Multiple, healthy and strong hale and hearty.

The all documents mentioned in the present invention are incorporated as reference the most in this application, just as each document It is individually recited as with reference to like that.In addition, it is to be understood that after the above-mentioned teachings having read the present invention, The present invention can be made various changes or modifications by those skilled in the art, and these equivalent form of values fall within this Shen equally Please appended claims limited range.

Claims (10)

1. health product, it is characterised in that described health product contain the extract of raw material or raw material, its Described in raw material include, wherein said raw material includes: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, mountain cornel Meat, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli,

Further, the weight portion of described raw material is as follows:

To sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part, Radix Asparagi 3-7 part, Fructus Corni 1-5 Part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part.

2. a combination for raw material, described combination include following raw material: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli, and, the weight of described raw material Amount part is as follows:

To sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part, Radix Asparagi 3-7 part, Fructus Corni 1-5 Part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part.

3. the purposes of the combination of raw material as claimed in claim 2, it is characterised in that be used for preparing reduction Blood glucose and the health product of blood fat.

4. the preparation method of health product, it is characterised in that said method comprising the steps of:

(a) provide raw material, described raw material includes: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli,

Further, the weight portion of described raw material is as follows: to sky fruit 8-12 part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part, Radix Asparagi 3-7 part, Fructus Corni 1-5 part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 part, Fructus Rubi 1-5 Part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part；

B () provides extract I and extract II；With

(c) mixed extract I and extract II, thus prepare described health product.

5. method as claimed in claim 4, it is characterised in that in step (b), be used for preparing extraction The raw material of thing I includes: Xiang Tianguo, Fructus Ligustri Lucidi, Radix Achyranthis Bidentatae, and the weight portion of described raw material is as follows: to sky fruit 8-12 Part, Fructus Ligustri Lucidi 1-5 part, Radix Achyranthis Bidentatae 2-8 part.

6. method as claimed in claim 4, it is characterised in that in step (b), be used for preparing extraction The raw material of thing II includes: Radix Asparagi, Fructus Corni, Rhizoma Polygonati Odorati, Poria, Fructus Rubi, Fructus Lycii, Herb Gynostemmae Pentaphylli, institute The weight portion stating raw material is as follows: Radix Asparagi 3-7 part, Fructus Corni 1-5 part, Rhizoma Polygonati Odorati 1-3 part, Poria 1-5 Part, Fructus Rubi 1-5 part, Fructus Lycii 1-5 part, Herb Gynostemmae Pentaphylli 1-5 part.

7. method as claimed in claim 4, it is characterised in that in step (b), described extract I Preparation include step:

I () is passed through for the raw material preparing extract I and is pulverized, add alcoholic solution and extract, obtain alcohol extract；

(ii) above-mentioned alcohol extract is concentrated, obtain alcohol extraction concentrated solution, be dried, thus obtain described extract I.

8. method as claimed in claim 4, it is characterised in that in step (b), described extract II Preparation include step:

I the raw material being used for preparing extract II is added extraction in aqueous solution by (), obtain Aqueous extracts；

(ii) above-mentioned Aqueous extracts is concentrated, obtain water extracting liquid (thick extractum), be dried, thus carry described in obtaining Take thing II.

9. method as claimed in claim 4, it is characterised in that in step (c), including step:

I () extract I, extract II mix, pulverize, sieve, obtain extract powder I and extract powder II respectively；

(ii) by extract powder I and extract powder II according to the ratio mix homogeneously of 2:1, and with pharmaceutically can connect The carrier being subject to mixes, packaging, thus obtains described health product.

10. method as claimed in claim 9, it is characterised in that in described step (i), described extraction After thing I and extract II co-grinding, cross 60 mesh sieves.