CN105943826A - Traditional Chinese medicine pills for treating urticaria and preparation method and application thereof - Google Patents

Traditional Chinese medicine pills for treating urticaria and preparation method and application thereof Download PDF

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Publication number
CN105943826A
CN105943826A CN201610406096.0A CN201610406096A CN105943826A CN 105943826 A CN105943826 A CN 105943826A CN 201610406096 A CN201610406096 A CN 201610406096A CN 105943826 A CN105943826 A CN 105943826A
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chinese medicine
urticaria
medicine pill
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
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  • Biotechnology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
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  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses traditional Chinese medicine pills for treating urticaria. The traditional Chinese medicine pills are prepared from, by mass, 10-15 g of cacumen tamaricis, 10-15 g of honeysuckle flower, 5-10 g of mint, 5-10 g of herba ephedra, 5-10 g of radices sileris, 10-15 g of poria cocos, 3-5 g of liquorice root and 5-8 g of fritillaria cirrhosa. The invention further discloses a preparation method and application of the traditional Chinese medicine pills. Through the medicinal value of all the components in the traditional Chinese medicine pills and the compatibility effect of the components, the effects of promoting circulation of blood and activating blood, dispelling wind and eliminating dampness, eliminating skin itches, invigorating the spleen for eliminating dampness and the like are achieved, urticaria can be effectively treated, and the advantages of being good in treatment effect, low in cost and convenient to take are achieved.

Description

A kind of for Chinese medicine pill treating urticaria and preparation method thereof and application
Technical field
The present invention relates to a kind of Chinese medicine pill and preparation method thereof and application, particularly belong to a kind of for treating nettle Chinese medicine pill of measles and preparation method thereof and application, belong to Chinese medicine formula and applied technical field.
Background technology
Urticaria be exceed skin, clear border, time disappear when rising, the redness of skin lesion appearing without definite location or white pruritic Welt block.Doctor trained in Western medicine thinks relevant with factors such as medication medication allergy, and the traditional Chinese medical science think this disease mostly be taste become estranged, The intestines and stomach is damp and hot, wet to be stayed in skin, or insufficiency of vital energy and blood, weakened defensive QI, experiences ailment said due to cold or exposure, disharmony of nutrient QI with defensive QI, diarrhea due to damp pathogen Heresy can not reach caused thoroughly.
Summary of the invention
In order to solve the problems referred to above, it is an object of the invention to provide that a kind of side effect is little, good effect, expense Low, therapeutic effect is significantly for Chinese medicine pill treating urticaria and preparation method thereof and application.
For solving above-mentioned technical problem, the technical scheme is that
A kind of Chinese medicine pill for treating urticaria, the quality proportioning including following components and each component is:
Cacumen Tamaricis 10-15g；
Flos Lonicerae 10-15g；
Herba Menthae 5-10g；
Herba Ephedrae 5-10g；
Radix Saposhnikoviae 5-10g；
Poria 10-15g；
Radix Glycyrrhizae 3-5g；
Bulbus Fritillariae Cirrhosae 5-8g.
Further preferably, the quality proportioning including following components and each component is: Cacumen Tamaricis 15g；Flos Lonicerae 15g；Herba Menthae 8g；Herba Ephedrae 6g；Radix Saposhnikoviae 6g；Poria 10g；Radix Glycyrrhizae 5g；Bulbus Fritillariae Cirrhosae 5g.
The above-mentioned Chinese medicine pill for treating urticaria, it is also possible to include Cornu Saigae Tataricae powder 5-10g.
Preferably include Cornu Saigae Tataricae powder 8g.
And the manufacture method of a kind of above-mentioned Chinese medicine pill for treating urticaria, step is: by quality proportioning After each component being mixed, it is ground into fine powder, crosses 100 mesh sieves, add the glutinous rice flour general ball of 3g paste producing, then 40 Being dried at DEG C, every 1kg ball uses 60.9 medicinal cinnabar powder coatings, polishing, every ball weight 0.5g.
And the Chinese medicine pill that above-mentioned preparation method prepares is applied in the medicine of preparation treatment urticaria.
The invention have the benefit that the present invention passes through the medical value of each component in Chinese medicine pill, and mutually Between compatibility effect, there is the effects such as activating blood circulation, dispeiling pathogenic wind and removing dampness, elimination skin pruritus, invigorating spleen to remove dampness, Can effectively treat urticaria, and there is good effect, low cost, the advantage of taking convenience.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be described in detail.
As follows for the pharmacology analysis situation of component in Chinese medicine pill of the present invention:
Main component:
Cacumen Tamaricis: property is put down, sweet in the mouth, pungent, enters the heart, lung, stomach warp, dissipates wind, detoxifies, delivers rash, use In measles without adequate eruption, rheumatic arthralgia；
Flos Lonicerae: cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, qi-restoratives treatment wind Merit effect；
Herba Menthae: be used for treating skin rubella and scratch where it itches, the disease such as measles without adequate eruption；
Herba Ephedrae: acrid in the mouth, micro-hardship, has effect of diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema；
Radix Saposhnikoviae: there is effect of dispeiling pathogenic wind and removing dampness；
Bulbus Fritillariae Cirrhosae: bitter in the mouth, sweet, cold nature；Returning lung, heart channel, cure mainly acute mastitis, skin ulcer swells；
Poria: there is effect of invigorating spleen to remove dampness；
Radix Glycyrrhizae: there is the effect of QI invigorating coordinating the actions of various ingredients in a prescription；
Cornu Saigae Tataricae powder: property is salty, cold, sweet in the mouth, enter liver, heart channel, there is suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, clearly Effect of thermal detoxification.
Jointly act on after Chinese medicine pill prescription of the present invention, there is the remarkable efficacy of promoting blood circulation by removing wind.
Embodiment 1:
By quality proportioning by Cacumen Tamaricis 10g；Flos Lonicerae 10g；Herba Menthae 5g；Herba Ephedrae 5g；Radix Saposhnikoviae 5g；Poria 10g；Radix Glycyrrhizae 3g；After Bulbus Fritillariae Cirrhosae 5g mixing, it is ground into fine powder, crosses 100 mesh sieves, add glutinous rice flour 3g paste producing General ball, is then dried at 40 DEG C, and every 1kg ball uses 60.9 medicinal cinnabar powder coatings, polishing, every ball weight 0.5g。
Embodiment 2:
By quality proportioning by Cacumen Tamaricis 15g；Flos Lonicerae 15g；Herba Menthae 10g；Herba Ephedrae 10g；Radix Saposhnikoviae 10g；Fu Siberian cocklebur 15g；Radix Glycyrrhizae 5g；After Bulbus Fritillariae Cirrhosae 8g mixing, it is ground into fine powder, crosses 100 mesh sieves, add glutinous rice flour 3g The general ball of paste producing, is then dried at 40 DEG C, and every 1kg ball uses 60.9 medicinal cinnabar powder coatings, polishing, often Ball weight 0.5g.
Embodiment 3:
By quality proportioning by Cacumen Tamaricis 15g；Flos Lonicerae 15g；Herba Menthae 8g；Herba Ephedrae 6g；Radix Saposhnikoviae 6g；Poria 10g；Radix Glycyrrhizae 5g；After Bulbus Fritillariae Cirrhosae 5g mixing, it is ground into fine powder, crosses 100 mesh sieves, add glutinous rice flour 3g paste producing General ball, is then dried at 40 DEG C, and every 1kg ball uses 60.9 medicinal cinnabar powder coatings, polishing, every ball weight 0.5g。
Embodiment 4:
By quality proportioning by Cacumen Tamaricis 12g；Flos Lonicerae 12g；Herba Menthae 8g；Herba Ephedrae 8g；Radix Saposhnikoviae 8g；Poria 12g；Radix Glycyrrhizae 4g；Bulbus Fritillariae Cirrhosae 6g；After Cornu Saigae Tataricae powder 8g mixing, it is ground into fine powder, crosses 100 mesh sieves, add The general ball of glutinous rice flour 3g paste producing, is then dried at 40 DEG C, and every 1kg ball uses 60.9 medicinal cinnabar powder coatings, Polishing, every ball weight 0.5g.
Embodiment 5:
By quality proportioning by Cacumen Tamaricis 15g；Flos Lonicerae 15g；Herba Menthae 8g；Herba Ephedrae 6g；Radix Saposhnikoviae 6g；Poria 10g；Radix Glycyrrhizae 5g；Bulbus Fritillariae Cirrhosae 5g；After Cornu Saigae Tataricae powder 8g mixing, it is ground into fine powder, crosses 100 mesh sieves, add The general ball of glutinous rice flour 3g paste producing, is then dried at 40 DEG C, and every 1kg ball uses 60.9 medicinal cinnabar powder coatings, Polishing, every ball weight 0.5g.
For verifying the clinical effectiveness of invention formulation, carry out clinical experiment.
1, case selection standard:
All have clinically exceed skin, clear border, time disappear when rising, the redness of skin lesion appearing without definite location or white scabies The symptoms such as itching property welt block are all as the standard selecting case.
2, diagnostic criteria: skin have rash block, have scratching vestige, rash block higher than skin, yellow complexion, light red tongue, White and greasy fur, relaxed and soft pulse.
3, therapeutic scheme
Treatment group takes the Chinese medicine pill described in the embodiment of the present invention 3, each ball, every day twice, within 7 days, is one The individual course for the treatment of, taking 4 courses for the treatment of, matched group takes ketotifen, chlorphenamine, outer painting fluocinolone acetonide ointment orally.
4, the evaluation criteria course for the treatment of:
Recovery from illness: symptom is wholly absent without recurrence, without any discomfort symptom；
Effective: transference cure, without recurrence within 1 year；
Effective: symptom substantially alleviates, or partial symptoms disappearance, need continual cure；
Invalid: symptom does not has any improvement, even has the trend increased the weight of.
5, physical data
72 example patients are out-patient.It is randomly divided into treatment group and matched group.Treatment group 36 example, wherein, Male 20 example, women 16 example, age 15～42 years old, average 26 years old；Matched group 36 example, male 19 examples, women 17 example, age 9～38 years old, average 29 years old.In two groups, the course of disease is the longest 2 years, Short first quarter moon, average out to 1 year.Through statistical analysis, two groups of case-datas there was no significant difference (P < 0.05).
6, therapeutic effect:
Treatment group cures 18 examples, effective 12 examples, effective 4 examples, invalid 2 examples, and total effective rate is 94.4 %；Matched group cures 9 examples, effective 15 examples, effective 7 examples, invalid 5 examples, and total effective rate is 86.1 %, treatment group total effective rate, apparently higher than matched group, is specifically shown in Table 1.
1 liang of table group therapeutic effect compares
As shown in Table 1, the curative effect for the treatment of group is significantly better than matched group, further relates to Chinese medicine of the present invention Ball has significant curative effect to treatment urticaria.
The present invention is by the medical value of each component in Chinese medicine pill, and compatibility effect each other, has The effects such as activating blood circulation, dispeiling pathogenic wind and removing dampness, elimination skin pruritus, invigorating spleen to remove dampness, can effectively treat urticaria, And there is good effect, low cost, the advantage of taking convenience.
Above detailed description of the invention limits the present invention the most in any form, every with equivalent or equivalent transformation The technical scheme that obtained of mode, all fall within protection scope of the present invention.

Claims (6)

1. one kind for treating the Chinese medicine pill of urticaria, it is characterised in that includes following components and each component Quality proportioning is:
Cacumen Tamaricis 10-15g；
Flos Lonicerae 10-15g；
Herba Menthae 5-10g；
Herba Ephedrae 5-10g；
Radix Saposhnikoviae 5-10g；
Poria 10-15g；
Radix Glycyrrhizae 3-5g；
Bulbus Fritillariae Cirrhosae 5-8g.
A kind of Chinese medicine pill for treating urticaria the most according to claim 1, it is characterised in that bag The quality proportioning including following components and each component is: Cacumen Tamaricis 15g；Flos Lonicerae 15g；Herba Menthae 8g；Herba Ephedrae 6g；Radix Saposhnikoviae 6g；Poria 10g；Radix Glycyrrhizae 5g；Bulbus Fritillariae Cirrhosae 5g.
A kind of Chinese medicine pill for treating urticaria the most according to claim 1 and 2, it is characterised in that Also include Cornu Saigae Tataricae powder 5-10g.
A kind of Chinese medicine pill for treating urticaria the most according to claim 3, it is characterised in that also Including Cornu Saigae Tataricae powder 8g.
5. a manufacture method for the Chinese medicine pill for treating urticaria described in claim 1, its feature Being, step is: after each component being mixed by quality proportioning, is ground into fine powder, crosses 100 mesh sieves, adds glutinous The general ball of rice flour 3g paste producing, is then dried at 40 DEG C, and every 1kg ball uses 60.9 medicinal cinnabar powder coatings, Polishing, every ball weight 0.5g.
6. the Chinese medicine pill that a preparation method as claimed in claim 5 prepares is in preparation treatment urticaria Application on medicine.
CN201610406096.0A 2016-06-11 2016-06-11 Traditional Chinese medicine pills for treating urticaria and preparation method and application thereof Withdrawn CN105943826A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1965938A (en) * 2006-11-14 2007-05-23 陈江 Rubella beverage
CN101062175A (en) * 2007-05-23 2007-10-31 陈江 Schizonepeta and ledebouriella root soup
CN102872315A (en) * 2012-07-02 2013-01-16 李承平 Tablet group for clearing away lung-heat and preventing asthma
CN103690904A (en) * 2012-09-27 2014-04-02 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicinal decoction for treating urticaria
CN104474516A (en) * 2014-12-11 2015-04-01 青岛百瑞吉生物工程有限公司 Traditional Chinese medicine preparation for treating urticaria as well as preparation method and application of traditional Chinese medicine preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1965938A (en) * 2006-11-14 2007-05-23 陈江 Rubella beverage
CN101062175A (en) * 2007-05-23 2007-10-31 陈江 Schizonepeta and ledebouriella root soup
CN102872315A (en) * 2012-07-02 2013-01-16 李承平 Tablet group for clearing away lung-heat and preventing asthma
CN103690904A (en) * 2012-09-27 2014-04-02 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicinal decoction for treating urticaria
CN104474516A (en) * 2014-12-11 2015-04-01 青岛百瑞吉生物工程有限公司 Traditional Chinese medicine preparation for treating urticaria as well as preparation method and application of traditional Chinese medicine preparation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
贺菊乔: "《中医外科特色疗法》", 30 April 2016, 山西科学技术出版社 *
高学敏: "《中药学》", 28 February 2003, 中国中医药出版社 *

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