CN103908632A - Chinese herbal preparation for treating arthritis as well as preparation method and application thereof - Google Patents
Chinese herbal preparation for treating arthritis as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses Chinese herbal preparation for treating arthritis. The formula of the preparation comprises the following components by weight: 10g-15g of turmeric, 10g-15g of honeysuckle, 8g-10g of radix achyranthis bidentatae root, 5g-10g of radix paeoniae rubrathe, 8g-12g of root bark of the peony tree, 10g-12g of felwort, 5g-10g of hematoxylon and 5g-10g of peach kernel. The invention also discloses a preparation method and application of the Chinese herbal preparation. The Chinese herbal preparation disclosed by the invention can be used for effectively dispelling cold and removing dampness and promoting blood circulation to remove blood stasis by virtue of medicinal value of each component in the formula of the traditional Chinese medicine as well as compatibility effect of the components, and has the advantages of being good in curative effect, low in cost, and convenient to take.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof and application, especially belong to Chinese medicine preparation for the treatment of of arthritis and preparation method thereof and application, belong to Chinese medicine formula and applied technical field.
Background technology
Arthritis is a kind of inflammatory diseases that occurs in human synovial and surrounding tissue thereof, and in China, having at present arthritic patient just has more than 100,000,000, and number is also in continuous increase.Most people thinks that arthritis is joint inflammation, and therefore, common way is to eat nonsteroidal antiinflammatory drug to alleviate.Effectively treatment of arthritis of this kind of mode, severe patient, can cause arthropathy and encroach on heart, blood vessel, lungs, vision, neural etc., causes many complication.The pathogens such as the heresy that arthritis is damp and hot with affection of exogenous wind-cold is relevant with human righteousness's deficiency, and wind and cold is wet, easily invade human body a little less than human body deficiency of defensive qi time and cause a disease.Exposure to wind when sweating, sitting and lying wetland, paddle in spite of the rain etc., all can make the pathogens such as wind and cold is wet invade body meridians, stay in joint, cause passages through which vital energy circulates QI and blood impatency obstructed, stagnation of QI and blood may bring about pain.Therefore, arthritic effective treatment is extremely important.
Summary of the invention
In order to address the above problem, the object of the present invention is to provide that a kind of side effect is little, good effect, expense be low, therapeutic effect is significantly used for the treatment of arthritic Chinese medicine formula composition and preparation method thereof.
For solving the problems of the technologies described above, technical scheme of the present invention is:
The Chinese medicine preparation for the treatment of of arthritis, is characterized in that, the formula composition of every dose of Chinese medicine preparation comprises that the quality of following component and each component is respectively:
Rhizoma Curcumae Longae: 10-15g;
Flos Lonicerae: 10-15g;
Radix Achyranthis: 8-10g;
Radix Paeoniae Rubra: 5-10g;
Cortex Moutan: 8-12g;
Radix Gentianae: 10-12g;
Lignum Sappan: 5-10g;
Semen Persicae: 5-10g.
Further, the Chinese medicine preparation for the treatment of of arthritis is preferably, and the formula composition of every dose of Chinese medicine preparation comprises that the quality of following component and each component is respectively: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 10g; Radix Achyranthis: 10g; Radix Paeoniae Rubra: 10g; Cortex Moutan: 10g; Radix Gentianae: 10g; Lignum Sappan: 5g; Semen Persicae: 5g.
In addition, described be used for the treatment of arthritic Chinese medicine preparation, also comprise Caulis Piperis Kadsurae 10-15g.
And further, the Chinese medicine preparation for the treatment of of arthritis is preferably: the formula composition of every dose of Chinese medicine preparation comprises that the quality of following component and each component is respectively: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 15g; Radix Achyranthis: 8g; Radix Paeoniae Rubra: 5g; Cortex Moutan: 8g; Radix Gentianae: 10g; Lignum Sappan: 5g; Semen Persicae: 5g; Caulis Piperis Kadsurae 10g.
Be used for the treatment of the manufacture method of arthritic Chinese medicine preparation, it is characterized in that, after the described quality proportioning that is used for the treatment of each component in arthritic Chinese medicine preparation is mixed, pulverize and grind to form fine powder, cross 60-100 mesh sieve, then the fine powder after sieving is dropped in mixing and blending machine and fully mixed, and for subsequent use according to the metering, distributing, packaging of every dose.
And the application of above-mentioned Chinese medicine preparation in treatment of arthritis is characterized in that, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
Beneficial effect of the present invention is: the present invention is by the medical value of each component in Chinese medicine preparation, and compatibility effect each other, and effectively cold expelling drives wet, blood circulation promoting and blood stasis dispelling, has good effect, cost is low, the advantage of taking convenience.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be described in detail.
Pharmacology analysis situation for each component in Chinese medicine preparation of the present invention is as follows:
Rhizoma Curcumae Longae: acrid in the mouth, hardship, return spleen, liver warp, for rheumatic arthralgia, especially upper limb arthralgia pain;
Flos Lonicerae: gas delicate fragrance, lightly seasoned, micro-hardship, returns lung, heart channel, has antiinflammatory, dredges the loose evil effect of heat;
Radix Achyranthis: sweet micro-acid, cool, enter the heart, liver, large intestine three warps, there is effect of promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing, the rheumatic arthralgia especially causing for treatment rheumatic arthritis has good curative effect;
Radix Paeoniae Rubra: bitter in the mouth, cold nature, return Liver Channel, there is effect of clots absorbing, pain relieving, removing heat from blood, detumescence,
Cortex Moutan: bitter in the mouth, pungent, is slightly cold.GUIXIN, liver, kidney channel, cure mainly: clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis; Rheumatism pyretic arthralgia;
Radix Gentianae: bitter in the mouth, cold in nature.Return liver, gallbladder meridian, heat clearing and damp drying, eliminating pathogen in the liver gallbladder excess-fire, except damp-heat in lower-JIAO, controls the inferior portion's rheumatism and damp and hot, and umbilicus swells and ache down to foot, the disturbance of lower legs due to pathogenic cold and dampness
Lignum Sappan: sweet; Salty; Xin Liang, the heart; Liver; Stomach; Spleen channel, blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain,
Semen Persicae: blood circulation promoting and blood stasis dispelling effect is very wide, availablely controls the various worn-out diseases of stagnation of blood stasis
Caulis Piperis Kadsurae: the effect with anti-inflammatory analgetic.
Side's justice is analyzed:
Rhizoma Curcumae Longae, Flos Lonicerae, Lignum Sappan and Caulis Piperis Kadsurae, have antiinflammatory, dredge that heat is loose evil, blood circulation promoting and blood stasis dispelling, the effect of subduing swelling and relieving pain, and three share, and not only can strengthen antiphlogistic effects, and expelling pathogenic wind from the body surface cold expelling, makes wind-cold damp pathogen loose from table, and get rid of evils and go out, and can relieving convulsion pain relieving; Radix Achyranthis, Radix Paeoniae Rubra and Radix Gentianae have effect of promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing, and three's compatibility share, and has wind-damp dispelling, invigorating the liver and kidney, and bone and muscle strengthening effect, not only can cold-dispelling damp, and eliminating evil just wound.Be aided with again there is clearing away heat and cooling blood, Cortex Moutan and the Lignum Sappan of promoting blood circulation to remove blood stasis effect, relieving spasm to stop pain better, coordinating the actions of various ingredients in a prescription.
embodiment 1:
The component in arthritic Chinese medicine preparation that is used for the treatment of by described: Rhizoma Curcumae Longae: 15g; Flos Lonicerae: 15g; Radix Achyranthis: 8g; Radix Paeoniae Rubra: 5g; Cortex Moutan: 8g; Radix Gentianae: 12g; Lignum Sappan: 10g; Semen Persicae: 10g pulverizes and grinds to form fine powder after mixing, and crosses 60 mesh sieves, in fine powder input mixing and blending machine that then will be after sieving, fully mix, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 2:
The component in arthritic Chinese medicine preparation that is used for the treatment of by described: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 10g; Radix Achyranthis: 10g; Radix Paeoniae Rubra: 10g; Cortex Moutan: 10g; Radix Gentianae: 10g; Lignum Sappan: 5g; Semen Persicae: 5g pulverizes and grinds to form fine powder after mixing, and crosses 80 mesh sieves, in fine powder input mixing and blending machine that then will be after sieving, fully mix, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 3:
The component in arthritic Chinese medicine preparation that is used for the treatment of by described: Rhizoma Curcumae Longae: 12g; Flos Lonicerae: 12g; Radix Achyranthis: 9g; Radix Paeoniae Rubra: 8g; Cortex Moutan: 10g; Radix Gentianae: 11g; Lignum Sappan: 8g; Semen Persicae: 8g pulverizes and grinds to form fine powder after mixing, and crosses 100 mesh sieves, in fine powder input mixing and blending machine that then will be after sieving, fully mix, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 4:
The component in arthritic Chinese medicine preparation that is used for the treatment of by described: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 10g; Radix Achyranthis: 8g; Radix Paeoniae Rubra: 5g; Cortex Moutan: 8g; Radix Gentianae: 12g; Lignum Sappan: 10g; Semen Persicae: 5g; Caulis Piperis Kadsurae 10g pulverizes and grinds to form fine powder after mixing, and crosses 60 mesh sieves, in fine powder input mixing and blending machine that then will be after sieving, fully mix, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 5:
The component in arthritic Chinese medicine preparation that is used for the treatment of by described: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 15g; Radix Achyranthis: 8g; Radix Paeoniae Rubra: 5g; Cortex Moutan: 8g; Radix Gentianae: 10g; Lignum Sappan: 5g; Semen Persicae: 5g; Caulis Piperis Kadsurae 10g pulverizes and grinds to form fine powder after mixing, and crosses 80 mesh sieves, in fine powder input mixing and blending machine that then will be after sieving, fully mix, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 6:
The component in arthritic Chinese medicine preparation that is used for the treatment of by described:: Rhizoma Curcumae Longae: 12g; Flos Lonicerae: 12g; Radix Achyranthis: 9g; Radix Paeoniae Rubra: 8g; Cortex Moutan: 10g; Radix Gentianae: 11g; Lignum Sappan: 8g; Semen Persicae: 8g; Caulis Piperis Kadsurae 12g pulverizes and grinds to form fine powder after mixing, and crosses 100 mesh sieves, in fine powder input mixing and blending machine that then will be after sieving, fully mix, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
For the clinical effectiveness of checking preparation of the present invention, carry out clinical experiment.
1, case selection standard:
All have the symptoms such as joint, the whole body or muscle contracture, swelling, pain, stiff, activity is unfavorable clinically all as the standard of selecting case.
2, diagnostic criteria
Pain of joint muscle, joint stuffiness; Arthralgia migration, migratory pain; Arthralgia is more acute, localized pain, and pain increase in intensity under coldness, pain alleviated while getting warmth, local color of the leather is not red, and that touches is not hot; Limbs joint is ached do not weighing and is moved, or has swelling, and numbness of the skin is meciless, overcast and rainyly increases the weight of or shows effect; Arthralgia, local scorching hot redness, pain can not be touched, and joint motion is unfavorable, can involve multiple joints, with fever and aversion to wind, thirsty unhappiness.
3, therapeutic scheme
Treatment group is taken the Chinese medicine preparation described in the embodiment of the present invention 2, every day potion, be a course for the treatment of at twice, 7 day every day, takes 3-5 the course for the treatment of, matched group is taken nonsteroidal antiinflammatory drug.
4, the course for the treatment of evaluation criteria:
Recovery from illness: symptom disappears completely without recurrence, without any discomfort symptom;
Effective: transference cure, 1 year with interior nothing recurrence;
Effective: symptom obviously alleviates, or partial symptoms disappearance, need continual cure;
Invalid: symptom does not have any improvement, even there is the trend increasing the weight of.
5, physical data
65 routine patients are out-patient.Be divided at random treatment group and matched group.Treatment group 33 examples, wherein, male's 8 examples, women's 25 examples, 32～72 years old age, average 53 years old; Matched group 32 examples, routine women's 26 examples of male 6,38～68 years old age, average 51 years old.In two groups, the course of disease is the longest 18 years, the shortest 2 years, average out to 10 years.Epidemiological Analysis by statistics, two groups of case-data there was no significant differences (P<0.05).
6, therapeutic effect:
Treatment group is cured 16 examples, effective 10 examples, and effective 4 examples, invalid 3 examples, total effective rate is 90.9%; Matched group is cured 7 examples, effective 5 examples, and effective 8 examples, invalid 12 examples, total effective rate is 62.5%, treatment group total effective rate is apparently higher than matched group, specifically in table 1.
Table 1 liang group therapeutic effect comparison
| Group | Number of cases | Cure | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 33 | 16 | 10 | 4 | 3 | 90.9 |
| Matched group | 32 | 7 | 5 | 8 | 12 | 62.5 |
7, model case:
(1) Mrs Wang, 46 years old.Before 2 years, in succession occurred bilateral proximal interphalangeal joint, metacarpophalangeal joints, carpal joint, knee joint swelling pain, morning, deadlock was greater than 1 hour, floating patella test (+), the rheumatoid factor positive, X mating plate get involved as seen joint bone erosion or decalcification, light red tongue, white and thin fur, floating pulse.One twice-daily is taken, and after 3 courses for the treatment of, arthralgia disappears, and continues to take two courses for the treatment of and consolidates curative effect, follows up a case by regular visits to not recurrence after half a year.
(2) Mr. Zhang, 64 years old.Within 7 years, cause is paddled and is cultivated for a long time, occur that right knee joint is ached weighing, and swelling, numbness of the skin is meciless, overcast and rainy increasing the weight of, floating patella test (+), red tongue, tongue is greasy in vain, relaxed and soft pulse.Take this Chinese medicine one day twice, treated for 5 courses for the treatment of, disease disappears, and follows up a case by regular visits to so far not recurrence.
The present invention is by the medical value of each component in Chinese medicine formula, and compatibility effect each other, and effectively cold expelling drives wet, blood circulation promoting and blood stasis dispelling, has good effect, cost is low, the advantage of taking convenience.
Above detailed description of the invention does not limit the present invention in any form, every to be equal to the technical scheme that mode was obtained of replacement or equivalent transformation, all drops in protection scope of the present invention.
Claims (6)
1. the Chinese medicine preparation for the treatment of of arthritis, is characterized in that, the formula composition of every dose of Chinese medicine preparation comprises that the quality of following component and each component is respectively:
Rhizoma Curcumae Longae: 10-15g;
Flos Lonicerae: 10-15g;
Radix Achyranthis: 8-10g;
Radix Paeoniae Rubra: 5-10g;
Cortex Moutan: 8-12g;
Radix Gentianae: 10-12g;
Lignum Sappan: 5-10g;
Semen Persicae: 5-10g.
2. be according to claim 1ly used for the treatment of arthritic Chinese medicine preparation, it is characterized in that, the formula composition of every dose of Chinese medicine preparation comprises that the quality of following component and each component is respectively: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 10g; Radix Achyranthis: 10g; Radix Paeoniae Rubra: 10g; Cortex Moutan: 10g; Radix Gentianae: 10g; Lignum Sappan: 5g; Semen Persicae: 5g.
3. be according to claim 1 and 2ly used for the treatment of arthritic Chinese medicine preparation, it is characterized in that, also comprise Caulis Piperis Kadsurae 10-15g.
4. be according to claim 1 and 2ly used for the treatment of arthritic Chinese medicine preparation, it is characterized in that, the formula composition of every dose of Chinese medicine preparation comprises that the quality of following component and each component is respectively: Rhizoma Curcumae Longae: 10g; Flos Lonicerae: 15g; Radix Achyranthis: 8g; Radix Paeoniae Rubra: 5g; Cortex Moutan: 8g; Radix Gentianae: 10g; Lignum Sappan: 5g; Semen Persicae: 5g; Caulis Piperis Kadsurae 10g.
5. be used for the treatment of the manufacture method of arthritic Chinese medicine preparation, it is characterized in that, after the described quality proportioning that is used for the treatment of each component in arthritic Chinese medicine preparation is mixed, pulverize and grind to form fine powder, cross 60-100 mesh sieve, then the fine powder after sieving is dropped in mixing and blending machine and fully mixed, and for subsequent use according to the metering, distributing, packaging of every dose.
6. the application of Chinese medicine preparation according to claim 5 in treatment of arthritis, is characterized in that, by fine powder every day of every dose of Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
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| CN105902953A (en) * | 2016-05-09 | 2016-08-31 | 青岛百瑞吉生物工程有限公司 | Traditional Chinese medicinal ointment for treating arthritis and preparation method thereof |
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| CN105902953A (en) * | 2016-05-09 | 2016-08-31 | 青岛百瑞吉生物工程有限公司 | Traditional Chinese medicinal ointment for treating arthritis and preparation method thereof |
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Application publication date: 20140709 |