CN105920564A - 一种治疗雷诺综合征的中药汤剂 - Google Patents
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Abstract
本发明公开了一种治疗雷诺综合征的中药汤剂,其由下列重量份的中药原料制成:桂枝10‑15g、熟地15‑30g、麻黄5‑10g、炮姜10‑15g、炙甘草5‑15g、陈皮3‑6g、当归10‑15g、白芍10‑15g、忍冬藤10‑15g、通草10‑15g、银杏叶20‑30g、鹿角胶5‑15g、乌梢蛇10‑15g、刺葡萄根3‑6g、藤碎补15‑20g、野花椒叶1‑3g、蜈蚣1‑2条;本发明中药具有温阳散寒、益气补血、活血化瘀、温经通络之功效,可以有效治疗雷诺综合征,愈后不复发,对人体无毒副作用,完全可靠。
Description
技术领域
本发明涉及一种中药,具体涉及一种治疗雷诺综合征的中药汤剂。
技术背景
雷诺综合征是临床上常见的一种疾病,多发于20-40岁人群,女性多于男性;本病起病缓慢,遇冷发作或加重,一般多为对称性双手指发生病变,足趾亦可发生,发作时手指或足趾发凉、发麻、疼痛、发白或发紫,疾病晚期逐渐出现指甲粗糙变形,病变部位皮肤萎缩、变薄、发紧,指尖或甲床周围发生溃烂,并可引起感染;中医舌脉象可见,舌淡胖或青紫,苔白润,脉沉细,其常见病因病机为阳虚寒凝、气滞血瘀、气虚血瘀、痰瘀阻络;目前治疗雷诺综合征常用西药,这些西药疗效差,毒副作用大,无法根治,而目前的中药制剂疗程长,疗效欠佳,易复发,不能令人满意。
发明内容
本发明的目的在于克服现有技术的不足,提供一种治疗雷诺综合征的中药汤剂,其疗效显著,无毒副作用,可以有效治疗雷诺综合征,且不复发。
为实现上述目的,本发明采用的技术方案如下:
治疗雷诺综合征的中药汤剂,由下列重量份的中药原料制成:桂枝10-15g、熟地15-30g、麻黄5-10g、炮姜10-15g、炙甘草5-15g、陈皮3-6g、当归10-15g、白芍10-15g、忍冬藤10-15g、通草10-15g、银杏叶20-30g、鹿角胶5-15g、乌梢蛇10-15g、刺葡萄根3-6g、藤碎补15-20g、野花椒叶1-3g、蜈蚣1-2条。
治疗雷诺综合征的中药汤剂,由下列重量份的中药原料制成:桂枝15g、熟地30g、麻黄5g、炮姜10g、炙甘草10g、陈皮3g、当归10g、白芍15g、忍冬藤10g、通草10g、银杏叶20g、鹿角胶10g、乌梢蛇15g、刺葡萄根3g、藤碎补20g、野花椒叶2g、蜈蚣1条。
用法与用量:水煎服,每日1剂,分2-3次服用。
本发明的有益效果:
本发明中药汤剂配伍科学合理,各药物协同作用,共奏温阳散寒、益气补血、活血化瘀、温经通络之功效,可以有效治疗雷诺综合征,愈后不复发,对人体无毒副作用,无不良反应,完全可靠。
具体实施方式
实施例1:一种治疗雷诺综合征的中药汤剂,由下列重量的中药原料制成:桂枝15g、熟地30g、麻黄5g、炮姜10g、炙甘草10g、陈皮3g、当归10g、白芍15g、忍冬藤10g、通草10g、银杏叶20g、鹿角胶10g、乌梢蛇15g、刺葡萄根3g、藤碎补20g、野花椒叶2g、蜈蚣1条。
用法与用量:水煎服,每日1剂,分2-3次服用。
典型病例
病例1:方某,女,45岁,2016年3月24日初诊,主诉:双手指发凉、发麻、发白半年;刻诊:双手指发凉、发麻、发白,时有疼痛,吹冷风或沾冷水后上症加重,舌青紫,苔白润,脉沉细;证属阳虚寒凝,痰瘀阻络,治以温阳散寒,化瘀通络;予服本发明方剂,服用10剂后,双手指发凉、发麻、发白明显减轻,疼痛已除,继续服用15剂后,诸症消失,随访至今未复发。
病例2:袁某,男,38岁,2014年6月17日初诊;主诉:双手指及脚趾发凉、发麻、发紫1年余,刻诊:双手指及脚趾发凉、发麻、发紫,左脚第三四脚趾甲床周围溃烂疼痛,上症于遇冷时加重,舌胖大瘀暗,苔白润,脉沉细涩,证属阳虚寒凝,气虚血瘀;治以温阳散寒,益气活血。予服本发明方剂,服用10剂后,双手指及脚趾发凉、发麻、发紫有所减轻,脚趾溃烂疼痛有所缓解,继续服用10剂后,双手指病变基本消失,脚趾发凉、发麻、发紫、溃烂疼痛明显好转,再服15剂后,诸症消失,随访至今未复发。
病例3:李某,女,35岁,2015年9月27日初诊,主诉:双手指发凉、发麻、发白、疼痛8月余;刻诊:双手指发凉、发麻、发白、疼痛,伴畏寒怕冷、神疲乏力,骑车吹冷风后双手指发凉、发麻、发白、疼痛加重,舌淡胖,苔薄白,脉沉细,证属阳虚寒凝,气虚血瘀,治以温阳散寒,益气活血;予服本发明方剂,服用10剂后,双手指发凉、发麻、发白、疼痛有所减轻,畏寒怕冷、神疲乏力明显好转,继续服用20剂后,诸症消失。随访至今未复发。
Claims (2)
1.一种治疗雷诺综合征的中药汤剂,其特征在于,由下列重量份的中药原料制成:桂枝10-15g、熟地15-30g、麻黄5-10g、炮姜10-15g、炙甘草5-15g、陈皮3-6g、当归10-15g、白芍10-15g、忍冬藤10-15g、通草10-15g、银杏叶20-30g、鹿角胶5-15g、乌梢蛇10-15g、刺葡萄根3-6g、藤碎补15-20g、野花椒叶1-3g、蜈蚣1-2条。
2.根据权利要求1所述的一种治疗雷诺综合征的中药汤剂,其特征在于由下列重量份的中药原料制成:桂枝15g、熟地30g、麻黄5g、炮姜10g、炙甘草10g、陈皮3g、当归10g、白芍15g、忍冬藤10g、通草10g、银杏叶20g、鹿角胶10g、乌梢蛇15g、刺葡萄根3g、藤碎补20g、野花椒叶2g、蜈蚣1条。
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Publication number | Priority date | Publication date | Assignee | Title |
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CN116870129A (zh) * | 2023-08-16 | 2023-10-13 | 安徽中医药大学第一附属医院(安徽省中医院) | 一种治疗结缔组织病相关雷诺现象的温经通脉复方中药 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103845620A (zh) * | 2014-03-02 | 2014-06-11 | 马青 | 一种用于治疗雷诺氏病的中药 |
CN104043087A (zh) * | 2014-06-25 | 2014-09-17 | 梁黎明 | 一种治疗雷诺氏综合症的中药组合物 |
CN105535878A (zh) * | 2014-11-03 | 2016-05-04 | 陈琼芳 | 一种治疗雷诺综合征的复方药 |
-
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- 2016-06-24 CN CN201610463327.1A patent/CN105920564A/zh active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103845620A (zh) * | 2014-03-02 | 2014-06-11 | 马青 | 一种用于治疗雷诺氏病的中药 |
CN104043087A (zh) * | 2014-06-25 | 2014-09-17 | 梁黎明 | 一种治疗雷诺氏综合症的中药组合物 |
CN105535878A (zh) * | 2014-11-03 | 2016-05-04 | 陈琼芳 | 一种治疗雷诺综合征的复方药 |
Non-Patent Citations (2)
Title |
---|
倪爱华等: "阳和汤治疗雷诺氏病60例", 《实用中医药杂志》 * |
南喜连: "中西医结合治疗雷诺氏病40例疗效观察", 《实用中西医结合临床》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN116870129A (zh) * | 2023-08-16 | 2023-10-13 | 安徽中医药大学第一附属医院(安徽省中医院) | 一种治疗结缔组织病相关雷诺现象的温经通脉复方中药 |
CN116870129B (zh) * | 2023-08-16 | 2024-03-26 | 安徽中医药大学第一附属医院(安徽省中医院) | 一种治疗结缔组织病相关雷诺现象的温经通脉复方中药 |
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