CN105920306A - Preparation method of oral liquid - Google Patents

Preparation method of oral liquid Download PDF

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Publication number
CN105920306A
CN105920306A CN201610223329.3A CN201610223329A CN105920306A CN 105920306 A CN105920306 A CN 105920306A CN 201610223329 A CN201610223329 A CN 201610223329A CN 105920306 A CN105920306 A CN 105920306A
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Prior art keywords
parts
radix
liquid
cervi pantotrichum
oral liquid
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CN201610223329.3A
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Inventor
李颖
王洪珍
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TONGHUA WANTONG PHARMACEUTICAL CO Ltd
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TONGHUA WANTONG PHARMACEUTICAL CO Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a preparation method of an oral liquid. The oral liquid includes: by weight, 70-90 parts of ginseng, 500-1000 parts of radix astragali, 500-900 parts of radix codonopsis, 400-600 parts of radix ophiopogonis, 200-400 parts of angelica sinensis, 200-400 parts of roasted rhizoma atractylodis macrocephalae, 200-400 parts of rehmannia glutinosa, 200-400 parts of prepared fleeceflower root, 200-300 parts of schisandra chinensis, 200-400 parts of dried orange peel, 200-300 parts of cortex lycii radicis, 10 g-20 g of cornua cervi pantotrichum, 400-600 parts of herba epimedii, 1000-2000 parts of cane sugar, 2000-3000 parts of processed honey, 1-10 parts of orange essence, and 5-15 parts of ethylparaben. The oral liquid configurates twelve traditional Chinese medicines scientifically and reasonably, has effect of reinforcing qi and nourishing blood, and is used for treating the symptoms of shortness of breath, palpitation, lusterless complexion, body tired fatigue and the like caused by deficiency of qi and blood.

Description

A kind of preparation method of oral liquid
Technical field
The present invention relates to medical field, particularly relate to the preparation method of a kind of oral liquid.
Background technology
The deficiency of vital energy in insufficiency of vital energy and blood i.e. Chinese medicine and blood deficiency.The result of insufficiency of vital energy and blood can cause function Go down, cause the pathological changes of senilism.The deficiency of vital energy: i.e. function decline resistance against diseases is poor.The deficiency of vital energy is then feared Cold cold extremities, spontaneous perspiration, dizziness and tinnitus, lethargy, tired unable, shortness of breath and palpitation, hypoevolutism. Blood deficiency: lusterless complexion is sallow, xerosis cutis, hair are withered, fingernail is dry and cracked, blurring of vision, brothers Numbness, insomnia and dreamful sleep, forgetful cardiopalmus, absentminded.Benefiting QI and nourishing blood oral liquid, benefiting QI and nourishing blood.With Weak in the cardiopalmus of breathing hard caused by insufficiency of vital energy and blood, lustreless complexion, body void.Benefiting QI and nourishing blood oral liquid, benefit Gas nourishes blood, weak for the cardiopalmus of breathing hard caused by insufficiency of vital energy and blood, lustreless complexion, body void, but existing In technology, the medicine of benefiting QI and nourishing blood is less, and preparation technology flow process of the prior art is the most complicated, in system Easily cause the waste of raw material during Bei, be also easy to make raw material produce bigger physics in preparation process Chemical change, affects drug effect.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, it is an object of the invention to provide the preparation of a kind of oral liquid Method, it is provided that the medicine of a kind of benefiting QI and nourishing blood, improves the purity of medicine.
Technical scheme is as follows:
A kind of preparation method of oral liquid, it comprises the following steps:
A, weigh according to weight portion Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae, Cortex Lycii, Cornu Cervi Pantotrichum and Herba Epimedii, cut into slices Cornu Cervi Pantotrichum, to Cornu Cervi Pantotrichum Boiling secondary in section, each 3 hours, collecting decoction, filter, filtrate is concentrated at 20 DEG C Under the conditions of relative density be 1.2--1.25, then think concentrated solution adds triplication ethanol, stand 24 hours, Filter, reclaim ethanol, obtain Cornu Cervi Pantotrichum reserve liquid；
B, by Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, Radix Polygoni Multiflori Preparata, five Taste, Pericarpium Citri Reticulatae, Cortex Lycii and Herba Epimedii boiling secondary, 3 hours for the first time, 2 is little for the second time Time, it is then combined with decoction liquor, filters, be concentrated to give mixing for standby use liquid；
C, Cornu Cervi Pantotrichum reserve liquid is merged with mixing for standby use liquid, obtains amalgamation liquid, then according to weight portion to Amalgamation liquid adds sucrose, refined honey, then boils 30 minutes, cooling, obtain coolant, to cooling Liquid adds Fructus Citri tangerinae essence, ethyl hydroxybenzoate, adds water to appropriate, stir evenly, filter, obtain described oral Liquid.
Described preparation method, wherein, the component of above-mentioned oral liquid includes according to weight portion: 70-90 part Radix Ginseng, the Radix Astragali of 500 parts-1000 parts, the Radix Codonopsis of 500 parts-900 parts, the wheat of 400 parts-600 parts Winter, the Radix Angelicae Sinensis of 200 parts-400 parts, the Rhizoma Atractylodis Macrocephalae (parched) of 200 parts-400 parts, the Radix Rehmanniae of 200 parts-400 parts, The Radix Polygoni Multiflori Preparata of 200 parts-400 parts, the Fructus Schisandrae Chinensis of 200 parts-300 parts, the Pericarpium Citri Reticulatae of 200 parts-400 parts, The Cortex Lycii of 200 parts-300 parts, the Cornu Cervi Pantotrichum of 10g-20g, the Herba Epimedii of 400 parts-600 parts, 1000 parts The sucrose of-2000 parts, the refined honey of 2000 parts-3000 parts, the Fructus Citri tangerinae essence of 1 part-10 parts and 5 part-15 The ethyl hydroxybenzoate of part.
12 taste Chinese medicines are carried out scientific and reasonable by the preparation method of a kind of oral liquid that the present invention provides Configuration, benefiting QI and nourishing blood, empty weak etc. for the cardiopalmus of breathing hard caused by insufficiency of vital energy and blood, lustreless complexion, body Symptom, and in preparation process to prepare environment ratio shallower, it is to avoid each component produces acutely Physicochemical change, improve drug effect and the purity of muscles and bones film.
Detailed description of the invention
The invention provides the preparation method of a kind of oral liquid, for making the purpose of the present invention, technical scheme And effect is clearer, clear and definite, the present invention is described in more detail below.Should be appreciated that herein Described specific embodiment, only in order to explain the present invention, is not intended to limit the present invention.
The invention provides the preparation method of a kind of oral liquid, it comprises the following steps:
Step 101: according to weight portion weigh Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae, Cortex Lycii, Cornu Cervi Pantotrichum and Herba Epimedii, cut into slices Cornu Cervi Pantotrichum, Boiling secondary in Cornu Cervi Pantotrichum is cut into slices, each 3 hours, collecting decoction, filter, filtrate is concentrated into Under the conditions of 20 DEG C, relative density is 1.2--1.25, then thinks to add in concentrated solution triplication ethanol, stands 24 hours, filter, reclaim ethanol, obtain Cornu Cervi Pantotrichum reserve liquid；
Step 102: by Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, what head of system Crow, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae, Cortex Lycii and Herba Epimedii boiling secondary, 3 hours for the first time, second Secondary 2 hours, it is then combined with decoction liquor, filters, be concentrated to give mixing for standby use liquid；
Step 103: Cornu Cervi Pantotrichum reserve liquid is merged with mixing for standby use liquid, obtains amalgamation liquid, then according to weight Amount part adds sucrose, refined honey, then boils 30 minutes, and cooling obtains coolant, in coolant Add Fructus Citri tangerinae essence, ethyl hydroxybenzoate, add water to appropriate, stir evenly, filter, obtain described oral liquid.
And the component of above-mentioned oral liquid includes according to weight portion: the Radix Ginseng of 70-90 part, 500 part-1000 Part the Radix Astragali, the Radix Codonopsis of 500 parts-900 parts, the Radix Ophiopogonis of 400 parts-600 parts, 200 parts-400 parts work as Return, the Rhizoma Atractylodis Macrocephalae (parched) of 200 parts-400 parts, the Radix Rehmanniae of 200 parts-400 parts, what is first for the system of 200 parts-400 parts Crow, the Fructus Schisandrae Chinensis of 200 parts-300 parts, the Pericarpium Citri Reticulatae of 200 parts-400 parts, the Cortex Lycii of 200 parts-300 parts, The Cornu Cervi Pantotrichum of 10g-20g, the Herba Epimedii of 400 parts-600 parts, the sucrose of 1000 parts-2000 parts, 2000 parts The refined honey of-3000 parts, the Fructus Citri tangerinae essence of 1 part-10 parts and the ethyl hydroxybenzoate of 5 parts-15 parts.
Illustrate with the most detailed following embodiment.
It is first according to weight portion and weighs the Radix Ginseng of 8.3g, the Radix Astragali of 83.4g, the Radix Codonopsis of 75g, 50g wheat Winter, 33.3g Radix Angelicae Sinensis, 33.3g Rhizoma Atractylodis Macrocephalae (parched), 33.3g Radix Rehmanniae, 30g Radix Polygoni Multiflori Preparata, 25g Fructus Schisandrae Chinensis, 33.3g Pericarpium Citri Reticulatae, 25g Cortex Lycii, 1.7g Cornu Cervi Pantotrichum and 50g Herba Epimedii, then cut into slices Cornu Cervi Pantotrichum, Xiang Lu Boiling secondary in fine and soft section, each 3 hours, collecting decoction, filter, filtrate is concentrated at 20 DEG C Under the conditions of relative density be 1.2--1.25, then think concentrated solution adds triplication ethanol, stand 24 hours, Filter, reclaim ethanol, obtain Cornu Cervi Pantotrichum reserve liquid；
Then by Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae, Cortex Lycii and Herba Epimedii boiling secondary, 3 hours for the first time, for the second time 2 Hour, it is then combined with decoction liquor, filters, be concentrated to give mixing for standby use liquid；
Finally Cornu Cervi Pantotrichum reserve liquid is merged with mixing for standby use liquid, obtain amalgamation liquid, then according to weight portion In amalgamation liquid, add the refined honey of the sucrose of 133g, 267g, then boil 30 minutes, cooling, cooled down Liquid, adds the Fructus Citri tangerinae essence of 0.5ml, the ethyl hydroxybenzoate of 1g in coolant, adds water to 1000ml, Stir evenly, filter, obtain described oral liquid.
It should be appreciated that the application of the present invention is not limited to above-mentioned citing, to ordinary skill For personnel, can be improved according to the above description or convert, all these modifications and variations are all answered Belong to the protection domain of claims of the present invention.

Claims (2)

1. a preparation method for oral liquid, it comprises the following steps:
A, weigh according to weight portion Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, Pericarpium Citri Reticulatae, Cortex Lycii, Cornu Cervi Pantotrichum and Herba Epimedii, cut into slices Cornu Cervi Pantotrichum, to Cornu Cervi Pantotrichum Boiling secondary in section, each 3 hours, collecting decoction, filter, filtrate is concentrated at 20 DEG C Under the conditions of relative density be 1.2--1.25, then think concentrated solution adds triplication ethanol, stand 24 hours, Filter, reclaim ethanol, obtain Cornu Cervi Pantotrichum reserve liquid；
B, by Radix Ginseng, the Radix Astragali, Radix Codonopsis, Radix Ophiopogonis, Radix Angelicae Sinensis, Rhizoma Atractylodis Macrocephalae (parched), Radix Rehmanniae, Radix Polygoni Multiflori Preparata, five Taste, Pericarpium Citri Reticulatae, Cortex Lycii and Herba Epimedii boiling secondary, 3 hours for the first time, 2 is little for the second time Time, it is then combined with decoction liquor, filters, be concentrated to give mixing for standby use liquid；
C, Cornu Cervi Pantotrichum reserve liquid is merged with mixing for standby use liquid, obtains amalgamation liquid, then according to weight portion to Amalgamation liquid adds sucrose, refined honey, then boils 30 minutes, cooling, obtain coolant, to cooling Liquid adds Fructus Citri tangerinae essence, ethyl hydroxybenzoate, adds water to appropriate, stir evenly, filter, obtain described oral Liquid.
Preparation method the most according to claim 1, it is characterised in that the component of above-mentioned oral liquid Include according to weight portion: the Radix Ginseng of 70-90 part, the Radix Astragali of 500 parts-1000 parts, 500 parts-900 parts Radix Codonopsis, the Radix Ophiopogonis of 400 parts-600 parts, the Radix Angelicae Sinensis of 200 parts-400 parts, the Rhizoma Atractylodis Macrocephalae (parched) of 200 parts-400 parts, The Radix Rehmanniae of 200 parts-400 parts, the Radix Polygoni Multiflori Preparata of 200 parts-400 parts, the Fructus Schisandrae Chinensis of 200 parts-300 parts, The Pericarpium Citri Reticulatae of 200 parts-400 parts, the Cortex Lycii of 200 parts-300 parts, the Cornu Cervi Pantotrichum of 10g-20g, 400 part-600 Part Herba Epimedii, the sucrose of 1000 parts-2000 parts, the refined honey of 2000 parts-3000 parts, 1 part-10 parts Fructus Citri tangerinae essence and the ethyl hydroxybenzoate of 5 parts-15 parts.
CN201610223329.3A 2016-03-31 2016-03-31 Preparation method of oral liquid Pending CN105920306A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101310751A (en) * 2007-05-23 2008-11-26 北京亚东生物制药有限公司 Traditional Chinese medicine composition for replenishing qi and blood, preparation method and quality control method thereof
CN101953986A (en) * 2009-07-21 2011-01-26 通药制药集团股份有限公司 Method for preparing Chinese medicinal preparation for treating Qi deficiency and blood deficiency

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101310751A (en) * 2007-05-23 2008-11-26 北京亚东生物制药有限公司 Traditional Chinese medicine composition for replenishing qi and blood, preparation method and quality control method thereof
CN101953986A (en) * 2009-07-21 2011-01-26 通药制药集团股份有限公司 Method for preparing Chinese medicinal preparation for treating Qi deficiency and blood deficiency

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Application publication date: 20160907