CN105920163A - External traditional Chinese medicine composition, preparation method thereof and application - Google Patents
External traditional Chinese medicine composition, preparation method thereof and application Download PDFInfo
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- CN105920163A CN105920163A CN201610448063.2A CN201610448063A CN105920163A CN 105920163 A CN105920163 A CN 105920163A CN 201610448063 A CN201610448063 A CN 201610448063A CN 105920163 A CN105920163 A CN 105920163A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention relates to an external traditional Chinese medicine composition which is prepared from raw materials including, in weight, 20-30 parts of golden cypress, 45-55 parts of forging fossil fragments, 25-35 parts of terra flavausta, 10-15 parts of borax and 5-10 parts of borneol. The invention further provides a preparation method of the traditional Chinese medicine composition and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition meets traditional Chinese medicine theories and has the functions of diminishing inflammation, relieving pain, removing necrotic tissues, facilitating convergence and strongly promoting tissue regeneration, wound can be effectively healed, and the composition is simple to prepare and convenient to use.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine composition, be specifically related to a kind of external medicine composition and
Preparation method and application.
Background technology
Surgical infection refers to need the infectious disease of operative treatment and occur at wound or postoperative infection, surgical infection
The most visible, the medicament categories for the treatment of surgical infection is more at present, it may have certain curative effect, but exists and control
Treatment functions is single or the shortcoming for the treatment of cycle length.
Summary of the invention
It is an object of the invention to provide a kind of anti-inflammatory analgetic, putrefaction removing convergence, granulation promoting power for above-mentioned the deficiencies in the prior art
Strong external medicine composition.
It is a further object of the present invention to provide the preparation method of this Chinese medicine composition.
Present invention also offers the application in preparation treatment surgical infection medicine of this Chinese medicine composition.
It is an object of the invention to be achieved through the following technical solutions: a kind of Chinese medicine composition, be characterized in, this Chinese drug-treated group
Compound is made up of the raw material of Chinese medicine of following weight proportion:
Cortex Phellodendri 20-30；
Forging Os Draconis 45-55；
Terra Flava Usta 25-35；
Borax 10-15；
Borneolum Syntheticum 5-10.
Described Chinese medicine composition, is preferably made up of the raw material of Chinese medicine of following weight proportion:
Cortex Phellodendri 25；
Forging Os Draconis 50；
Terra Flava Usta 30；
Borax 10；
Borneolum Syntheticum 5.
Described Chinese medicine composition, can use pharmaceutical methods conventional in Chinese materia medica, make external preparation.
Described Chinese medicine composition, can use pharmaceutical methods conventional in Chinese materia medica, be preferably made unguentum, powder, water
Agent, tincture, liniment, spray or membrane.
The pharmaceutical formulation of described Chinese medicine composition is preferably unguentum, containing medical ventolin in described unguentum.
Present invention also offers the preparation method of Chinese medicine composition described in above technical scheme, its step is as follows:
(1) by prescription raw material pulverizing the powder mix homogeneously that obtains after sieving, mixed-powder is obtained；
(2) it is heated to medical ventolin melting；
(3) the medical ventolin temperature in step (2) is cooled to 30 ~ 40 DEG C, then 7:3 in mass ratio is slowly added to step wherein
Suddenly the mixed-powder in (1), stirring while adding limit cooling, until receiving cream, obtaining final product.
The preparation method of described Chinese medicine composition, in step (1), described in sieve after the powder diameter scope that obtains exist
160 ~ 180 mesh.
Described Chinese medicine composition may be used for the medicine of preparation treatment surgical infection.
Surgical infection of the present invention includes the infectious disease needing the ischemic necrosis of operative treatment to cause, such as cotton-padded mattress
Skin ulcer, diabetic foot, varicose veins of the lower extremity, artery of lower extremity thromboembolism etc., also include nonspecific infection, as scabies, carbuncle, cellulitis, Serpentis are broken
Skin ulcer, paronychia etc., also include postoperative infection, and wound, burn and scald, cold injury, chemical injury.
The herbal nature that Chinese medicine composition of the present invention is used is as follows:
Cortex Phellodendri: composition is little Bai alkali, obacunone, obakulactone etc., and enterobacteria, Bacillus typhi positive cocci are had stronger sterilization
Effect；
Os Draconis (calcined): composition is calcium carbonate, calcium phosphate, for hemostasis astringent；
Terra Flava Usta: composition contains silicic acid, aluminium oxide, ferrum, sodium, potassium, magnesium, zinc, for hemostasis astringent；
Borax: composition is sodium tetraborate, function is anticorrosion, detoxifies, except malignant boil；
Borneolum Syntheticum: composition is dextro Borneolum Syntheticum, function is antiinflammatory, detumescence, heat clearing away, pain relieving.
Chinese medicine composition of the present invention meets Chinese medical theory, has anti-inflammatory analgetic, putrefaction removing convergence, effect that granulation promoting power is strong,
Wound healing can be effectively facilitated, and prepare simple, easy to use.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.Should be appreciated that tool described herein
Body embodiment only in order to explain the present invention, is not intended to limit the present invention.
Embodiment 1, a kind of Chinese medicine composition, this Chinese medicine composition is prepared from the following raw materials in parts by weight: Cortex Phellodendri 20g,
Forging Os Draconis 45g, Terra Flava Usta 25g, Borax 10g, Borneolum Syntheticum 5g.
Embodiment 2, a kind of Chinese medicine composition, this Chinese medicine composition is prepared from the following raw materials in parts by weight:
Cortex Phellodendri 30g, forging Os Draconis 55g, Terra Flava Usta 35g, Borax 15g, Borneolum Syntheticum 10g.
Embodiment 3, a kind of Chinese medicine composition, this Chinese medicine composition is prepared from the following raw materials in parts by weight:
Cortex Phellodendri 25g, forging Os Draconis 50g, Terra Flava Usta 30g, Borax 10g, Borneolum Syntheticum 5g.
Embodiment 4, the preparation method of the Chinese medicine composition described in embodiment 13 any one, its step is as follows:
(1) take each pulverizing medicinal materials 160 mesh screens excessively in prescription, obtain each Chinese medicinal powder, by above-mentioned powder mix homogeneously, to obtain final product
Mixed-powder；
(2) it is heated to medical ventolin melting；
(3) the medical ventolin temperature in step (2) is cooled to 30 DEG C, then 7:3 in mass ratio is slowly added to step wherein
(1) mixed-powder in, stirring while adding limit cooling, until receiving cream, obtaining Traditional Chinese medicine composition paste of the present invention.
Embodiment 5, the preparation method of the Chinese medicine composition described in embodiment 1 or 2, its step is as follows:
(1) take each pulverizing medicinal materials 180 mesh screens excessively in prescription, obtain each Chinese medicinal powder, by above-mentioned powder mix homogeneously, to obtain final product
Mixed-powder；
(2) it is heated to medical ventolin melting；
(3) the medical ventolin temperature in step (2) is cooled to 40 DEG C, then 7:3 in mass ratio is slowly added to step wherein
(1) mixed-powder in, stirring while adding limit cooling, until receiving cream, obtaining Traditional Chinese medicine composition paste of the present invention.
Embodiment 6, the preparation method of the Chinese medicine composition described in embodiment 3, its step is as follows:
(1) take each pulverizing medicinal materials 180 mesh screens excessively in prescription, obtain each Chinese medicinal powder, by above-mentioned powder mix homogeneously, to obtain final product
Mixed-powder；
(2) it is heated to medical ventolin melting；
(3) the medical ventolin temperature in step (2) is cooled to 40 DEG C, then 7:3 in mass ratio is slowly added to step wherein
(1) mixed-powder in, stirring while adding limit cooling, until receiving cream, obtaining Traditional Chinese medicine composition paste of the present invention.
When the Traditional Chinese medicine composition paste that above-described embodiment 46 prepares uses, with hydrogenperoxide steam generator, affected part is carried out disinfection
After wipe dry, remove slough, affected part higher depth with Traditional Chinese medicine composition paste pharmacy yarn drain of the present invention, the drug of topical application, wrapping, every day
Change dressings 1 time.
Embodiment 7, the preparation method of the Chinese medicine composition described in embodiment 13 any one: take above-mentioned prescription raw material powder
Cross 160 mesh screens after broken, obtain each Chinese medicinal powder, by above-mentioned powder mix homogeneously, obtain Chinese medicine composition composition powders of the present invention, make
Used time, dress affected part with vinegar, honey, Oleum Sesami etc., wrapping, change dressings every day 1 time.
Embodiment 8, the preparation method of the Chinese medicine composition described in embodiment 13 any one: take above-mentioned prescription raw material powder
Cross 180 mesh screens after broken, obtain each Chinese medicinal powder, by above-mentioned powder mix homogeneously, obtain Chinese medicine composition composition powders of the present invention, make
Used time, dress affected part with vinegar, honey, Oleum Sesami etc., change dressings every day 1 time.
Embodiment 9, the preparation method of the Chinese medicine composition described in embodiment 13 any one: take each medical material in prescription,
According to conventional decocting for Chinese herbal medicine technological operation, filtering medicinal residues, obtain Chinese medicine composition water preparation of the present invention, during use, external is cleaned and is suffered from
Place, every day 2-3 time.
Embodiment 10, the preparation method of the Chinese medicine composition described in embodiment 13 any one: take each medical material in prescription
It is ground into powder, mixing, put in airtight porcelain altar, add 80% ethanol solution of 4 times of weight, airtight dipping 48h, cross and filter
Medicinal residues, the filtrate airtight standing 24h obtained, filter, add appropriate distilled water and stir, making concentration of alcohol is 70%-
75%, obtain Chinese medicine composite tincture of the present invention, during use, affected part, every day 2-3 time are cleaned in external.
Embodiment 11, Clinical practice is tested.
The patient suffering from wound and surgical infection is controlled by the Traditional Chinese medicine composition paste of the present invention that Application Example 6 prepares
Treat, during use, wipe dry after affected part being carried out disinfection with hydrogenperoxide steam generator, remove slough, the affected part higher depth present invention
Chinese medicine composition pharmacy yarn drain, the drug of topical application, wrapping, change dressings every day 1 time.Therapeutic effect is as shown in table 1.
The therapeutic effect of Chinese medicine composition of the present invention used by table 1..
As shown in Table 1, Chinese medicine composition of the present invention is to mild trauma infection, tissue ischemia downright bad (decubital ulcer), skin sense
Dye (Serpentis break skin ulcer, furuncle carbuncle), burn and scald infection, mechanical traumatic infection, Complication included infection etc. are respectively provided with preferable curative effect
And safety, effective percentage reaches more than 80%.
Above example is only the preferred embodiment of the present invention, it is noted that to those skilled in the art,
Without departing from the principles of the invention, done some improvement, also should be regarded as protection scope of the present invention.
Claims (8)
1. an external medicine composition, it is characterised in that this Chinese medicine composition is prepared from the following raw materials in parts by weight:
Cortex Phellodendri 20-30；
Forging Os Draconis 45-55；
Terra Flava Usta 25-35；
Borax 10-15；
Borneolum Syntheticum 5-10.
Chinese medicine composition the most according to claim 1, it is characterised in that this Chinese medicine composition is former by following weight proportion
Material is made:
Cortex Phellodendri 25；
Forging Os Draconis 50；
Terra Flava Usta 30；
Borax 10；
Borneolum Syntheticum 5.
Chinese medicine composition the most according to claim 1 and 2, it is characterised in that this Chinese medicine composition uses in Chinese materia medica normal
The pharmaceutical methods of rule, makes external preparation.
Chinese medicine composition the most according to claim 3, it is characterised in that this Chinese medicine composition uses routine in Chinese materia medica
Pharmaceutical methods, makes unguentum, powder, water preparation, tincture, liniment, spray or membrane.
Chinese medicine composition the most according to claim 4, it is characterised in that the pharmaceutical formulation of described Chinese medicine composition is cream
Agent, containing medical ventolin in described unguentum.
6. the preparation method of a Chinese medicine composition as claimed in claim 5, it is characterised in that its step is as follows:
(1) by pulverizing medicinal materials each in prescription the powder mix homogeneously that obtains after sieving, mixed-powder is obtained；
(2) it is heated to medical ventolin melting；
(3) the medical ventolin temperature in step (2) is cooled to 30 ~ 40 DEG C, then 7:3 in mass ratio is slowly added to step wherein
Suddenly the mixed-powder in (1), stirring while adding limit cooling, until receiving cream, obtaining final product.
Chinese medicine composition the most according to claim 6, it is characterised in that in step (1), described in sieve after the powder that obtains
End particle size range is at 160 ~ 180 mesh.
8. a Chinese medicine composition as claimed in claim 1 or 2, said composition answering in preparation treatment surgical infection medicine
With.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610448063.2A CN105920163A (en) | 2016-06-21 | 2016-06-21 | External traditional Chinese medicine composition, preparation method thereof and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610448063.2A CN105920163A (en) | 2016-06-21 | 2016-06-21 | External traditional Chinese medicine composition, preparation method thereof and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105920163A true CN105920163A (en) | 2016-09-07 |
Family
ID=56830938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610448063.2A Pending CN105920163A (en) | 2016-06-21 | 2016-06-21 | External traditional Chinese medicine composition, preparation method thereof and application |
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| Country | Link |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973674A (en) * | 2019-05-24 | 2020-11-24 | 大连关爱糖尿病研究所有限公司 | Ointment for treating diabetic foot ulcer and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133720A (en) * | 1995-04-17 | 1996-10-23 | 曹杏贤 | Specific plaster for treatment of malignant sore |
| CN1140077A (en) * | 1995-10-26 | 1997-01-15 | 王希平 | Medical ointment (powder) for removing necrotic tissue and promoting tissue regeneration |
| CN1330949A (en) * | 2000-06-29 | 2002-01-16 | 刘国群 | Powdered medicine for treating aphtha by spraying it |
| CN101716281A (en) * | 2008-10-09 | 2010-06-02 | 孟险峰 | Traditional Chinese medicine paste for promoting tissue regeneration and recovering wounds and production method thereof |
| CN103705735A (en) * | 2013-12-11 | 2014-04-09 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicine powder for stopping bleeding and diminishing inflammation |
-
2016
- 2016-06-21 CN CN201610448063.2A patent/CN105920163A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133720A (en) * | 1995-04-17 | 1996-10-23 | 曹杏贤 | Specific plaster for treatment of malignant sore |
| CN1140077A (en) * | 1995-10-26 | 1997-01-15 | 王希平 | Medical ointment (powder) for removing necrotic tissue and promoting tissue regeneration |
| CN1330949A (en) * | 2000-06-29 | 2002-01-16 | 刘国群 | Powdered medicine for treating aphtha by spraying it |
| CN101716281A (en) * | 2008-10-09 | 2010-06-02 | 孟险峰 | Traditional Chinese medicine paste for promoting tissue regeneration and recovering wounds and production method thereof |
| CN103705735A (en) * | 2013-12-11 | 2014-04-09 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicine powder for stopping bleeding and diminishing inflammation |
Non-Patent Citations (1)
| Title |
|---|
| 明•方广: "《丹溪心法附余》", 31 December 2015, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973674A (en) * | 2019-05-24 | 2020-11-24 | 大连关爱糖尿病研究所有限公司 | Ointment for treating diabetic foot ulcer and preparation method thereof |
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Application publication date: 20160907 |
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