CN105902879A - Chinese medicinal composition for treating bronchial asthma - Google Patents
Chinese medicinal composition for treating bronchial asthma Download PDFInfo
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract
The invention discloses a Chinese medicinal composition for treating bronchial asthma. The composition is mainly prepared from the following raw materials in parts by weight: 35-55 parts of human placenta, 20-40 parts of earthworm, 5-20 parts of liriope muscari, 5-10 parts of fritillaria, 5-20 parts of radix glehniae and 2-5 parts of clam meal. The Chinese medicinal composition has an excellent effect of treating bronchial asthma, basically does not cause adverse response, and is suitable for bronchial asthma patients.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to treat the Chinese medicine composition of bronchial asthma.
Background technology
Bronchial asthma is the chronic airway inflammation disease participated in by various kinds of cell (such as eosinophilic granulocyte, mastocyte, T lymphocyte, neutrophilic granulocyte, human airway epithelial cells etc.) and cellular component.This chronic inflammatory disease is relevant to airway hyperreactivity, generally occurs within extensive reversible airflow limitation, and causes the symptoms such as the panting of repeated relapsing, out of breath, uncomfortable in chest or cough.
It is now recognized that bronchial asthma is a kind of polygenic inheritance disease having obvious Familial aggregation to be inclined to, its generation had not only been affected by inherited genetic factors but also by environmental factors.Additionally, allergen is risk factor, dust mite is modal allergen, is the most important pathogenic factors of asthma.Common are 4 kinds, i.e. dermatophagoides pteronyssinus, dust mite, euroglyphus maynei and hirsutism demodicid mite.Dermatophagoides pteronyssinus is the topmost acarid of constant humid weather.Fungus is also present in one of allergen in room air, common for penicillium sp, aspergillosis, Alternaria etc..Fructus Psoraleae and grass meal are the modal outdoor allergens causing asthma attack.Xylophyta (tree Fructus Psoraleae) often causes asthma in spring, and the careless class powder of gramineae plant often causes asthma in autumn.
There is uncomfortable in chest, asthma and the symptom such as dyspnea, cough of recurrent exerbation in typical bronchial asthma.Often there are the premonitory symptoms such as nasal obstruction, sneeze, ophthalmic pruritus, outbreak severe patient that severe dyspnea, hypoxemia can occur in the short time before outbreak.Sometimes cough is only symptom (cough variant asthma).Show effect in night or morning and increase the weight of to be one of the feature of asthma.Symptoms of asthma can be shown effect in several minutes.Some symptom weight can spontaneous remission, but major part needs positive treatment.Chinese patent medicine lacks the significant modern Chinese medicine of drug effect, still can not meet the needs of the Bronchial Asthmas of clinical application.
Summary of the invention
A kind of medicine for treating bronchial asthma of offer is provided, by selecting suitable medical material and proportioning thereof, reaches safely and effectively to be applied to the purpose of Treating Bronchial Asthma.
The present invention is achieved through the following technical solutions: the Chinese medicine composition for the treatment of bronchial asthma, mainly it is made up of the raw material of Chinese medicine of following weight portion: Placenta Hominis 35-55 part, Pheretima 20-40 part, 5-20 part big Radix Ophiopogonis, Bulbus Fritillariae Uninbracteatae 5-10 part, Radix Glehniae 5-20 part, Pulvis concha Mactrae 5-10 part, bosom Pheretima 5-10 part, Fructus Psoraleae 10-20 part, Radix Saposhnikoviae 10-15 part, Semen Coicis 10-25 part, Radix Cynanchi Paniculati 5-15 part.
To better implement the present invention, further, mainly it is made up of the raw material of Chinese medicine of following weight portion: Placenta Hominis 40 parts, Pheretima 30 parts, big Radix Ophiopogonis 10 parts, Bulbus Fritillariae Uninbracteatae 5 parts, Radix Glehniae 10 parts, Pulvis concha Mactrae 5 parts, bosom Pheretima 5 parts, Fructus Psoraleae 20 parts, Radix Saposhnikoviae 15 parts, Semen Coicis 10 parts, Radix Cynanchi Paniculati 5 parts.
To better implement the present invention, further, its dosage form is oral liquid, granule, tablet, capsule, pill or powder.
To better implement the present invention, further, its dosage form is granule.
The preparation method of the above-mentioned Chinese prescription for treating diabetes, the dosage form of this prescription described is granule, and its method comprises the following steps:
1) by the Placenta Hominis of weight portion, Pheretima, big Radix Ophiopogonis, Bulbus Fritillariae Uninbracteatae, Radix Glehniae, Pulvis concha Mactrae, cherishing Pheretima, Fructus Psoraleae, Radix Saposhnikoviae, Semen Coicis, Radix Cynanchi Paniculati is cleaned, and joins in multi-function extractor and decocts three times, filters, merging filtrate；
2) filtrate of upper step is heated the thick paste that relative density when being concentrated into 60 DEG C is 1.27-1.33 and obtains extractum；
3) extractum and pharmaceutic adjuvant are mixed and made into oral liquid, granule, capsule, pill or powder.
Wherein, decocting the soak by water that includes for three times adding for the first time 10 times amount 2 hours, second time adds the soak by water 1 hour of 8 times amount, and third time adds the soak by water 1 hour of 6 times amount.
The present invention compared with prior art, has the following advantages and beneficial effect:
The Chinese prescription of the present invention, treats bronchial asthma excellent effect, substantially has no adverse reaction, and is suitable for Bronchial Asthmas treatment and takes.
Detailed description of the invention
The present invention is expanded on further, it should be appreciated that embodiment is merely to illustrate the present invention rather than limits the scope of the invention below in conjunction with specific embodiment.
Embodiment 1:
For treating the Chinese prescription of diabetes, mainly it is made up of the raw material of Chinese medicine of following weight: Placenta Hominis 40 parts, Pheretima 30 parts, big Radix Ophiopogonis 10 parts, Bulbus Fritillariae Uninbracteatae 5 parts, Radix Glehniae 10 parts, Pulvis concha Mactrae 5 parts, cherishes Pheretima 5 parts, Fructus Psoraleae 20 parts, Radix Saposhnikoviae 15 parts, Semen Coicis 10 parts, Radix Cynanchi Paniculati 5 parts.
The preparation method of the above-mentioned Chinese prescription for treating diabetes, the dosage form of this prescription described is granule, and its method comprises the following steps:
1) by the Placenta Hominis of weight portion, Pheretima, big Radix Ophiopogonis, Bulbus Fritillariae Uninbracteatae, Radix Glehniae, Pulvis concha Mactrae, cherishing Pheretima, Fructus Psoraleae, Radix Saposhnikoviae, Semen Coicis, Radix Cynanchi Paniculati is cleaned, and joins in multi-function extractor and decocts three times, filters, merging filtrate；
2) filtrate of upper step is heated the thick paste that relative density when being concentrated into 60 DEG C is 1.27-1.33 and obtains extractum；
3) extractum and pharmaceutic adjuvant are mixed and made into oral liquid, granule, capsule, pill or powder.
Wherein, decocting the soak by water that includes for three times adding for the first time 10 times amount 2 hours, second time adds the soak by water 1 hour of 8 times amount, and third time adds the soak by water 1 hour of 6 times amount.
By step 2) extractum and adjuvant dextrin press the weight ratio mix and blend of 1:2, pelletize, granulate, prepare granule, load dress, prepared granule.Every bag of 3g Han extractum.
Embodiment 2:
Bronchial Asthmas 100 example, is randomly divided into 2 groups.Treatment group 30 example, male 11 examples, female 19 example, age 37-70 year, 56.5 years old mean age, course of disease 0.5-9；Matched group 30 example, male 14 examples, female 16 example, age 33-68 year, 54.5 years old mean age, course of disease 1-9.5.There is not significant difference between two groups of Genders, age, courses of disease, there is comparability.
Diagnostic criteria:
(1) recurrent exerbation asthma, out of breath, uncomfortable in chest or cough, how with to contact allergen, cold air, physics, chemical stimulation, viral upper respiratory tract infection, motion relevant；
(2) at bilateral audible and be dispersed in or diffusivity, wheezing sound based on expiratory phase, expiratory phase prolongation during outbreak；
(3) above-mentioned symptom can be alleviated or spontaneous remission through treatment；
(4) asthma that except, other diseases causes, out of breath, uncomfortable in chest or cough；
(5) during its atypical clinical manifestations person at least should have following three: 1. brinchial provocation test or exercise test are positive；2. Bronchodilation Test is positive；PEF aberration rate >=20% the most round the clock.Meet 1-4 bar or 4,5 persons, bronchial asthma can be diagnosed as.
5, research method
5.1 Therapeutic Method
Treatment group takes the granule that the present invention prepares according to specific embodiment 1, and every bu morning, noon and afternoon take for three times.
All treat 2 weeks for two groups.
Points for attention: avoid contact with the allergens such as pollen, dust, air, animal lint.
Criterion of therapeutical effect:
Clinic control: symptoms of asthma complete incidence graph, even if having mild episode to be not required to medication once in a while can alleviate, FEV1 (or PEF) >=80% predicted value after FEV1 (or PEF) increments ＞ 35%, or treatment, PEF day and night fluctuation rate ＜ 20%；
Effective: symptoms of asthma substantially alleviates, FEV1 (or PEF) increases 25%-35%, or FEV1 (or PEF) reaches predicted value 60%-79%, PEF day and night fluctuation rate ＞ 20% after treatment, it is still necessary to 17-hydroxy-11-dehydrocorticosterone or bronchodilator；Take a turn for the better: symptoms of asthma has alleviated, and FEV1 (or PEF) increases 15%-24%, it is still necessary to 17-hydroxy-11-dehydrocorticosterone or bronchodilator；Invalid: clinical symptoms and FEV1 (or PEF) measured value are without improving or increasing the weight of.
Curative effect
After treating 2 weeks, treatment group patient reaches 42 examples of clinic control, effective 25 examples, and take a turn for the better 12 examples, invalid 5 examples；Matched group reaches 30 examples of clinic control, effective 16 examples, and take a turn for the better 3 examples, invalid 11 examples.There is significant significant difference, P ＜ 0.05 in two groups of total effective rates, the curative effect for the treatment of group is substantially better than matched group.
Embodiment 3:
Classical case:
Certain, female, 74 years old, suffers from chronic cough and asthma disease existing more than 10 years, often shows effect seriously to White Dew.Once informal dress Radix Glycyrrhizae tabellae, asthma-relieving bolus of gecko, aerosol etc..This is examined is to be introduced by friend, and Sanya, Hainan to be arrived is recuperated at once, and spy asks a side so that it is can spend winter in comfort.Patient's obesity, but out of puff, sweating on head, sound such as expectorant blocks up, and pharyngeal often have a foreign body sensation, time send out cough, cough white glutinous foam sputum, speech can not be put down sleeping night, white and greasy fur, and pulse condition is heavy carefully.Two base of lung audibles and tiny moist rale.Comprehensive analysis to both pulse condition and symptoms, is for lung kidney qi Yin bivacuity, and expectorant is turbid to be hindered in lung network.Method works as lung benefiting the kidney invigorating, drying dampness to eliminate phlegm, dredging collateral spasmolytic.Taking medicine after 3 courses for the treatment of, cough with asthma has no substantially outbreak so far, and health is also felt strength, fears cold and cool air the most as before.Sanya to be gone, drinks the state of an illness the most again and makes up a prescription at once.Quarter examines: energetic, with a smile, has no cough with asthma, states its stool the thinnest, frequent urination at night, white and greasy fur, and pulse condition stringy and thready pulse band is sliding.
King so-and-so, female, 53 years old, when 10 years old, flu caused bronchitis, the most all treats with western medicine and medical practitioners, and morbidity is just had an injection and taken medicine, and re-pull is had an injection and taken medicine.Because of malpractice, drag into chronic bronchitis and chronic bronchial asthma, in decades recurrent exerbation.Cough vapour lock, abundant expectoration during morbidity, accompanies pain uncomfortable in chest, asthma urgency, wheezing sound in the throat, body thin, and complexion is dark dim, ecchymosis, dark complexion easily occurs, and lip color is dark, and the eye corner of the eye is black dull, has a strong impact on work and life.Particularly the most easily show effect when having eaten the marors such as pineapple, Semen Sojae Preparatum, fish and shrimp or it the moon of chance rains, there's a sudden fall in temperature and catches a cold.How average onset 5-6 time within a year, show effect in autumn and winter, more than 40 year front and back.Take drug withdrawal after 4 courses for the treatment of of the present invention.Autumn and winter all do not fall ill then.Within the most several years, patient has no and sends out asthma more in the past.
Huang, man, 71 years old, suffer from asthma for many years, symptom: cough with asthma, cough gets up cannot rest, uncomfortable in chest out of breath, dyspnea, wheezing sound in the throat, body are thin, and complexion is dark dim, ecchymosis, dark complexion easily occur, lip color is dark, the eye corner of the eye is black dull, and squamous and dry skin is the most hemorrhage, tongue has petechia, thready and hesitant pulse, is asthma after diagnosing.Use the traditional Chinese medicine composition for treating of the present invention, oral, every day twice.Surrounding is a course for the treatment of, takes effect, can stop during cough within half a minute after 2 courses for the treatment of, breathes the most smooth and easy；Significantly taking a turn for the better after 6 courses for the treatment of, cough significantly reduces, and will not feel sensation of oppression over the chest with shortness of breath when breathing mild.After 10 courses for the treatment of, only cough once in a while, and discontinuously, no longer feel uncomfortable in chest during breathing, breathe hard, but vigorous exercise can not be done, cure.Visit after 1 year, have no recurrence.
Visible, bronchial asthma can safely and effectively be treated by the medicine that the present invention prepares, and has preferable medical science promotional value.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: these embodiments can carry out under without departing from the principle of the present invention and objective multiple change, revise, replace and modification, the scope of the present invention is limited by claim and equivalent thereof.
Claims (6)
1. treat the Chinese medicine composition of bronchial asthma, it is characterised in that be mainly made up of the raw material of Chinese medicine of following weight portion: Placenta Hominis 35-55 part, Pheretima 20-40 part, 5-20 part big Radix Ophiopogonis, Bulbus Fritillariae Uninbracteatae 5-10 part, Radix Glehniae 5-20 part, Pulvis concha Mactrae 2-5 part.
The Chinese medicine composition for the treatment of bronchial asthma the most according to claim 1, it is characterised in that be mainly made up of the raw material of Chinese medicine of following weight portion: Placenta Hominis 40 parts, Pheretima 30 parts, big Radix Ophiopogonis 10 parts, Bulbus Fritillariae Uninbracteatae 5 parts, Radix Glehniae 10 parts, Pulvis concha Mactrae 3 parts.
The Chinese medicine composition for the treatment of bronchial asthma the most according to claim 1 and 2, it is characterised in that in parts by weight, also includes cherishing Pheretima 5-10 part, Fructus Psoraleae 10-20 part, Radix Saposhnikoviae 10-15 part, Semen Coicis 10-25 part, Radix Cynanchi Paniculati 5-15 part.
The Chinese medicine composition for the treatment of bronchial asthma the most according to claim 3, it is characterised in that bosom Pheretima 5 parts, Fructus Psoraleae 20 parts, Radix Saposhnikoviae 15 parts, Semen Coicis 10 parts, Radix Cynanchi Paniculati 5 parts.
5. according to the Chinese medicine composition of the arbitrary described treatment bronchial asthma of claim 2 or 4, it is characterised in that its dosage form is oral liquid, granule, tablet, capsule, pill or powder.
The Chinese medicine composition for the treatment of bronchial asthma the most according to claim 5, it is characterised in that its dosage form is granule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233483A (en) * | 2017-06-30 | 2017-10-10 | 禹州市合同泰药业有限公司 | A kind of relieving cough and asthma prepared slices of Chinese crude drugs formula and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1134281A (en) * | 1995-11-28 | 1996-10-30 | 赵贵铭 | Medicine for asthma and its preparation |
| CN102258645A (en) * | 2011-07-21 | 2011-11-30 | 杨万明 | Medicine for treating bronchial asthma |
| CN104940852A (en) * | 2014-03-27 | 2015-09-30 | 刘黎明 | Traditional Chinese medicine composition for treating blood stasis type asthma |
| CN104940487A (en) * | 2015-06-05 | 2015-09-30 | 吴斌 | Medicine for treating bronchial asthma |
-
2016
- 2016-05-24 CN CN201610349417.8A patent/CN105902879A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1134281A (en) * | 1995-11-28 | 1996-10-30 | 赵贵铭 | Medicine for asthma and its preparation |
| CN102258645A (en) * | 2011-07-21 | 2011-11-30 | 杨万明 | Medicine for treating bronchial asthma |
| CN104940852A (en) * | 2014-03-27 | 2015-09-30 | 刘黎明 | Traditional Chinese medicine composition for treating blood stasis type asthma |
| CN104940487A (en) * | 2015-06-05 | 2015-09-30 | 吴斌 | Medicine for treating bronchial asthma |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233483A (en) * | 2017-06-30 | 2017-10-10 | 禹州市合同泰药业有限公司 | A kind of relieving cough and asthma prepared slices of Chinese crude drugs formula and preparation method thereof |
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