CN105899486A - 用于治疗癌症的化合物和方法 - Google Patents

用于治疗癌症的化合物和方法 Download PDF

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Publication number
CN105899486A
CN105899486A CN201480072152.0A CN201480072152A CN105899486A CN 105899486 A CN105899486 A CN 105899486A CN 201480072152 A CN201480072152 A CN 201480072152A CN 105899486 A CN105899486 A CN 105899486A
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CN
China
Prior art keywords
cancer
methods
crystal form
therapy
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480072152.0A
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English (en)
Chinese (zh)
Inventor
J·C·小阿门迪奥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Su Aikang Pharmaceutical Co Ltd Of Japan
Original Assignee
Su Aikang Pharmaceutical Co Ltd Of Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Su Aikang Pharmaceutical Co Ltd Of Japan filed Critical Su Aikang Pharmaceutical Co Ltd Of Japan
Publication of CN105899486A publication Critical patent/CN105899486A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/72—Aliphatic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/285—Arsenic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/36—Arsenic; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201480072152.0A 2013-12-05 2014-12-05 用于治疗癌症的化合物和方法 Pending CN105899486A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361912044P 2013-12-05 2013-12-05
US61/912,044 2013-12-05
PCT/US2014/068859 WO2015085208A1 (en) 2013-12-05 2014-12-05 Compounds and methods for the treatment of cancer

Publications (1)

Publication Number Publication Date
CN105899486A true CN105899486A (zh) 2016-08-24

Family

ID=53274177

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480072152.0A Pending CN105899486A (zh) 2013-12-05 2014-12-05 用于治疗癌症的化合物和方法

Country Status (6)

Country Link
US (1) US20160304546A1 (https=)
JP (1) JP2016540775A (https=)
KR (1) KR20160086960A (https=)
CN (1) CN105899486A (https=)
TW (1) TWI617305B (https=)
WO (1) WO2015085208A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2019220961A1 (ja) * 2018-05-18 2020-05-28 ソレイジア・ファーマ株式会社 ダリナパルシンのアルカリ金属塩及び／又は無機酸付加塩の結晶型及びその製剤

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101076533A (zh) * 2004-07-16 2007-11-21 得克萨斯州A&M大学系统 治疗癌症的化合物和方法
US20080090904A1 (en) * 2002-01-07 2008-04-17 The Texas A&M University System S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer
US20090053168A1 (en) * 2007-07-17 2009-02-26 Richard Rickles Treatments of b-cell proliferative disorders
CN101395166A (zh) * 2006-01-13 2009-03-25 得克萨斯州A&M大学系统 用于治疗癌症的化合物和方法
CN102149432A (zh) * 2008-08-20 2011-08-10 Zio医药肿瘤学公司 用于治疗癌症的有机砷化合物和方法
US20120022229A1 (en) * 2005-07-29 2012-01-26 Ziopharm Oncology, Inc. Compounds and methods for the treatment of cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200829261A (en) * 2006-09-29 2008-07-16 Ziopharm Oncology Inc Method for controlling angiogenesis in animals

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080090904A1 (en) * 2002-01-07 2008-04-17 The Texas A&M University System S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer
CN101076533A (zh) * 2004-07-16 2007-11-21 得克萨斯州A&M大学系统 治疗癌症的化合物和方法
US20120022229A1 (en) * 2005-07-29 2012-01-26 Ziopharm Oncology, Inc. Compounds and methods for the treatment of cancer
CN101395166A (zh) * 2006-01-13 2009-03-25 得克萨斯州A&M大学系统 用于治疗癌症的化合物和方法
US20090053168A1 (en) * 2007-07-17 2009-02-26 Richard Rickles Treatments of b-cell proliferative disorders
CN102149432A (zh) * 2008-08-20 2011-08-10 Zio医药肿瘤学公司 用于治疗癌症的有机砷化合物和方法

Also Published As

Publication number Publication date
JP2016540775A (ja) 2016-12-28
TW201531292A (zh) 2015-08-16
US20160304546A1 (en) 2016-10-20
TWI617305B (zh) 2018-03-11
WO2015085208A1 (en) 2015-06-11
KR20160086960A (ko) 2016-07-20

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