CN105876050A - Production method of cordyceps militaris polypeptide candy - Google Patents

Production method of cordyceps militaris polypeptide candy Download PDF

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Publication number
CN105876050A
CN105876050A CN201410657867.4A CN201410657867A CN105876050A CN 105876050 A CN105876050 A CN 105876050A CN 201410657867 A CN201410657867 A CN 201410657867A CN 105876050 A CN105876050 A CN 105876050A
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China
Prior art keywords
cordyceps militaris
production method
candy
liver
polypeptide
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Pending
Application number
CN201410657867.4A
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Chinese (zh)
Inventor
陈顺志
王林
许登泉
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JIANGSU XUEFU BIOLOGICAL ENGINEERING Co Ltd
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JIANGSU XUEFU BIOLOGICAL ENGINEERING Co Ltd
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Priority to CN201410657867.4A priority Critical patent/CN105876050A/en
Publication of CN105876050A publication Critical patent/CN105876050A/en
Pending legal-status Critical Current

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  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention aims to provide a production method of cordyceps militaris polypeptide candy which is high in practical value and good in combined effects, and the production method enters industrial production. The effects of the production method are as follows: sucrose is used to wrap the main ingredients of cordyceps militaris extract, reduced glutathione, vitamin E, etc., which can extend the validity period and increase the solubility, so that the cordyceps militaris polypeptide candy has better effects in relieving liver toxins.

Description

A kind of production method of Cordyce militaris polypeptide confection
Technical field
The present invention relates to the production method of a kind of Cordyce militaris polypeptide confection, belong to food processing technology field, particularly candy foods process technology.
Background technology
Liver is human body most important removing toxic substances organ, and hepatocellular synthesis, removing toxic substances, estrogen inactivation etc. are shielded by glutathion contained by it. When liver sustains damage, and such as suffers from various hepatopathy, human body helps injured liver to carry out self-regeneration reconciliation by consuming substantial amounts of glutathion Poison, internal glutathion will fall sharply.Due to hepatocyte nutrient and hepatocyte energy deficiency, body constitution will be caused to decline.Ethanol also can be made Becoming liver function to reduce, the toxicity of ethanol causes headache, lethargy, Nausea and vomiting.The factor that other external environment pollutes enters human body also can produce toxicity Effect, autologous metabolism also can produce removing toxic substances material, and the Detoxication of liver lacks, and body constitution will be caused to decline.Liver-fire too distinguished gathering two is rubescent, tired Unable, insomnia and immunity degradation;Often there is uncomfortable liver area, the sensation that pain is gloomy.They are the performances that toxicant is retarded by silt at liver.
Cordyceps militaris can alleviate the hepatocyte injury that the various factors such as chemical substance, medicine, virus cause, and reduces the liver function such as transaminase, bilirubin Index;Raise the liver complex functionality indexs such as blood albumin.Meanwhile, Cordyceps, by suppression TGF β 1 gene expression, reduces and has directly with liver cirrhosis The PDGF gene expression of relation, the main pathological change hepatic fibrosis of suppression liver cirrhosis, alleviate even reverse cirrhosis." solved by regulation Coupling protein 2 (UCP2) " level, alleviate endotoxemia, reduce tumor necrosis factor α (TNF α), thus suppress fatty liver.
Reduced glutathion, to strengthening the organ functions such as people body-centered, liver, kidney, brain, improves immunity, free radical resisting, defying age, cancer-resisting And relieving alcohol hepatic injury has obvious biological effect.It participates in biotransformation and internal harmful poisonous substance is changed into harmless material, protects Protect in numerous protein and enzyme equimolecular not by such as harmful substance Oxidative demages such as free radicals.
Vitamin E is sensitive to oxygen, the most oxidized, therefore can protect other the most oxidized materials, reduces the generation of lipid peroxide, and protection body is thin Born of the same parents, from the murder by poisoning of free radical, give full play to the particular physiological function of material to be protected.
So selecting Cordyceps militaris, reductive glutathione, vitamin E, form the most effective combination, but, their effective ingredient is susceptible to Change.There is important meaning by making Cordyce militaris polypeptide confection, because the reproducibility of the existence of sucrose, especially sucrose, prevent composition.Protect Demonstrate,prove product quality.Aoxidize product of the present invention and human hepatocyte's factor and the necessary nutrient of human body are provided, by combining poisonous chemical substance, Increase its dissolubility, progressively discharge, and have the effect solving liver poison.
Summary of the invention
It is an object of the invention to provide the production method of the Cordyce militaris polypeptide confection that a kind of practical value is high, combined effect is good, enter industrialized production.
The technology that the present invention uses, is characterized in that active component-reduced glutathion, the content of Cordyceps militaris extract can control, and the addition of sucrose is protected Demonstrate,prove the steady quality of product.
For achieving the above object, the technical solution used in the present invention is as follows:
The production method of a kind of Cordyce militaris polypeptide confection, comprises following component and weight proportion: Cordyceps militaris extract 100-300mg, reduced form paddy Guang Sweet peptide 50-75mg, vitamin E 30mg, sucrose 2-3g.
The optimum weight proportioning of 3 gram/confections made by the various raw material of the present invention: Cordyceps militaris extract 150mg, reduced glutathion 50mg, Vitamin E2 0mg, sucrose 2780mg.
A kind of production method of Cordyce militaris polypeptide confection, its step is as follows:
(1) Cordyceps militaris carry through water, concentrate, be spray-dried after obtain Cordyceps militaris extract;
(2) according to their weight ratio, it is mixed to get compositions, candy machine is processed into confection;
(3) under gmp conditions through sterilizing, pack, check, dispatching from the factory.
Effective active composition in Cordyceps militaris of the present invention includes the multiple biological active matters such as cordycepin, cordycepic acid, Cordyceps polysaccharide, superoxide dismutase Matter.Cordycepin, i.e. 3'-Deoxyadenosine, be similar to gland glycoside action, be a kind of nucleosides material with antibacterial activity, gathers core polyadenylic acid Synthase has the strongest inhibitory action, has antiviral, antibacterial activity.Cordycepic acid, i.e. mannitol, can suppress the growth of various pathogenic bacteria, promotes machine The metabolism of body.Superoxide dismutase, is a kind of very important antioxidase, and it can help the free radical that internal elimination is too much, it is to avoid Cell, by oxidation, aging or destruction, also waits suppression virus, strengthens immunologic function.Cordyceps polysaccharide has immunocompetence, can be remarkably reinforced body fluid with Cellular immune function, promotes antibody and the generation of interferon or antigen precursor reactant.
Compared with prior art, present invention have the advantage that
(1) it is a kind of special nutrient candy, is the good friend of liver;The test of composition proves tool through the laboratory (Shandong) of state approval The protective effect of standby protection chemical liver injury.
(2) utilizing reduced glutathion and the quality control of Cordyceps militaris extract, through protection and the Stabilization of sucrose, beneficially product is walked To international market;
(3) long shelf-life of product, stable components, taking convenience, have feasibility, has the health-care effect promoting immunity of organisms.
(4) product of the present invention provides hepatocellular important factor, by combining poisonous chemical substance, increases its dissolubility, progressively discharges body Outward, the effect of solution liver poison is played.So, hepatic injury there is is auxiliary protection function.
Effect of the invention is that: by sucrose, the main components such as Cordyceps militaris extract, reduced glutathion, vitamin E are formed parcel, prolong Long effect duration, increase its dissolubility, and have the effect preferably solving liver poison.
Detailed description of the invention
Embodiment 1:
The production method of a kind of Cordyce militaris polypeptide confection, comprises following component and weight proportion: Cordyceps militaris extract 100-300mg, reduced form paddy Guang Sweet peptide 50-75mg, vitamin E 30mg, sucrose 2-3g.
The optimum weight proportioning of 3 gram/confections made by the various raw material of the present invention: Cordyceps militaris extract 150mg, reduced glutathion 50mg, Vitamin E2 0mg, sucrose 2780mg.
According to their weight ratio, mix, sieving obtains compositions, is processed into Cordyce militaris polypeptide confection under gmp conditions on candy machine, can With individual packaging, it is also possible to 6-12 grain/plate packaging.Through sterilizing, pack, check, dispatching from the factory.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not restricted to the described embodiments, and any of other does not carries on the back The change made under spirit and the principle of the present invention, modify, substitute, combine, simplify, all should be the substitute mode of equivalence, be included in Protection scope of the present invention.

Claims (1)

1. the production method of a Cordyce militaris polypeptide confection, it is characterised in that comprise following component and weight proportion: Cordyceps militaris extract 100-300mg, Reduced glutathion 50-75mg, vitamin E 30mg, sucrose 2-3g.
CN201410657867.4A 2014-11-14 2014-11-14 Production method of cordyceps militaris polypeptide candy Pending CN105876050A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410657867.4A CN105876050A (en) 2014-11-14 2014-11-14 Production method of cordyceps militaris polypeptide candy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410657867.4A CN105876050A (en) 2014-11-14 2014-11-14 Production method of cordyceps militaris polypeptide candy

Publications (1)

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CN105876050A true CN105876050A (en) 2016-08-24

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003221343A (en) * 2002-01-25 2003-08-05 Noevir Co Ltd Supercritical extract of vegetative wasp
CN101088355A (en) * 2006-06-15 2007-12-19 富阳 Lung-heat clearing aweto candy and its making process
CN103652846A (en) * 2012-09-25 2014-03-26 江苏学府生物工程有限公司 Production method for cordyceps militaris buccal tablets
CN103652932A (en) * 2012-09-07 2014-03-26 江苏学府生物工程有限公司 Production method of Cordyceps militaris polypeptide tablet
CN103652940A (en) * 2012-09-07 2014-03-26 江苏学府生物工程有限公司 Production method of Cordyceps militaris polypeptide soft capsule

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003221343A (en) * 2002-01-25 2003-08-05 Noevir Co Ltd Supercritical extract of vegetative wasp
CN101088355A (en) * 2006-06-15 2007-12-19 富阳 Lung-heat clearing aweto candy and its making process
CN103652932A (en) * 2012-09-07 2014-03-26 江苏学府生物工程有限公司 Production method of Cordyceps militaris polypeptide tablet
CN103652940A (en) * 2012-09-07 2014-03-26 江苏学府生物工程有限公司 Production method of Cordyceps militaris polypeptide soft capsule
CN103652846A (en) * 2012-09-25 2014-03-26 江苏学府生物工程有限公司 Production method for cordyceps militaris buccal tablets

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Application publication date: 20160824