CN105857931A - Cell storage and transportation case and monitoring system - Google Patents

Cell storage and transportation case and monitoring system Download PDF

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Publication number
CN105857931A
CN105857931A CN201510979134.7A CN201510979134A CN105857931A CN 105857931 A CN105857931 A CN 105857931A CN 201510979134 A CN201510979134 A CN 201510979134A CN 105857931 A CN105857931 A CN 105857931A
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CN
China
Prior art keywords
cell storage
cell
box
conveying box
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201510979134.7A
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Chinese (zh)
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CN105857931B (en
Inventor
陈小功
徐艳红
张建强
肖升东
于丽娟
何晓文
刘莎
赵鸿莲
瞿建国
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai OriginCell Biological Cryo Equipment Co Ltd
Original Assignee
Beijing Origincell Medical Research Institute Co Ltd
Origincell Technology Group Co Ltd
Shanghai OriginCell Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Beijing Origincell Medical Research Institute Co Ltd, Origincell Technology Group Co Ltd, Shanghai OriginCell Medical Technology Co Ltd filed Critical Beijing Origincell Medical Research Institute Co Ltd
Priority to CN201510979134.7A priority Critical patent/CN105857931B/en
Publication of CN105857931A publication Critical patent/CN105857931A/en
Application granted granted Critical
Publication of CN105857931B publication Critical patent/CN105857931B/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • B65D25/10Devices to locate articles in containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • B65D81/05Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/38Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation
    • B65D81/3813Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Packages (AREA)

Abstract

The invention discloses a cell storage and transportation case and a monitoring system. The cell storage and transportation case comprises a case body, a case cover, constant-temperature boxes containing refrigerants, and a plurality of cell storage and transportation boxes. The constant-temperature boxes are arranged on the two opposite inner side walls of the case body, the bottom surface of the case body, and the inner side of the case cover. Internal fixing frames are arranged on the other two opposite inner side walls correspondingly. The multiple cell storage and transportation boxes are closely attached to one another and arranged in spaces formed by the constant-temperature boxes and the internal fixing frames, and cell bags are placed in the multiple cell storage and transportation boxes correspondingly. The monitoring system comprises a plurality of cell storage and transportation cases and a remote monitoring unit. A user is reminded to take effective measures by obtaining the temperature value and giving an alarm when the temperature is abnormal. According to the cell storage and transportation case and the monitoring system, the cell bags are stored in the cell storage and transportation boxes, the cell storage and transportation boxes are fixed through the constant-temperature boxes and the internal fixing frames, and the temperature of the cell storage and transportation boxes is monitored in real time, so that cells are stored and transported safely, and the practicability of cell storage and transportation is greatly improved.

Description

Cell storage and conveying box and monitoring system
Technical field
The present invention relates to cell storaging and transport technology field, particularly to a kind of cell storage and conveying box and monitoring system.
Background technology
Cell is as an independent life entity, and it has the plasticity ability of the strongest vitality, proliferation and differentiation ability and function.The mechanism of cytotherapeutic treatment disease is broadly divided into two big classes: one is the direct effect of cell, directly uses tissue and the organ of its specific biological activity repairing damage;Or play specificity/non-specific lethal effect;Two is the indirect action of cell, and the factor as relevant in secretion or bioactive molecule regulate propagation and the functional activity of patients own cells.
Cell therapy is the disease treatment new technique risen in recent years, refer to utilize some to have the characteristic of the cell of specific function, after using biological engineering method to obtain and/or being processed by amplification in vitro, specific culture etc., make these cells have enhancing immunity, kill the therapeutic efficiency such as pathogen and tumor cell, promotion tissue and organ regeneration and physical recovery, thus reach to treat the purpose of disease.No matter cell obtain and/or by amplification in vitro after during cell therapy etc., cell cold chain transportation becomes a step of interim key, particularly in cell long-distance transport, the quality of means of transport and way of transportation is directly connected to the activity of cell, eventually affects the scientific research of cell or the future use of cell therapy.
The Chinese patent " a kind of blood refrigerating transport case " of Publication No. CN204433408U, instant invention overcomes existing couveuse refrigeration undesirable, and it is difficult to ensure that cold preservation effective temperature and dry deficiency in casing, there is provided a kind of and be capable of contacting of reagent and ice chest larger area, there is good cooling effect.But this blood refrigerating transport case is only for being stored in the invisible spectro sample of small volume, if transported with cell bags collection, this invention does not substantially reach requirement.This invention is equipped with thermometer, transport the temperature inside the box can be detected, but it is a lack of the function of thermograph and warning, cause in transportation if it find that abnormal variations in temperature, because transport people or driver notice thermometer the most in time, that raises the cell in blood products, anticoagulant factor etc. are produced huge injury, particularly temperature, it will produce irreversible damage.The Chinese patent " portable blood transportation box " of Publication No. CN202557961U, existing storage box is optimized, solving handling cell bags will be from the turnover suitable for reading of transport case, operate very inconvenient, the power consumption of transportation is higher, the drawbacks such as entirety is heavier, but this invention is the simplest, whole process does not has any related facility of monitoring temperature, perception the most artificially judges, whole transportation is significant lower to the strict controlling of temperature, cannot detect and recorded the change of sample temperature in transport, when the fortuitous events such as traffic jam occur, vigor and the quality of cell sample may be had a strong impact on.
Summary of the invention
The technical problem to be solved in the present invention is to reduce the activity of cell in cell bags in order to overcome in prior art owing to cell bags causes rocking more greatly and vibrating without fixing device, and owing to lacking thermograph and warning function, the cell in cell storage and conveying box may be caused in residing temperature to exceed the defect of the huge injury that cell is produced by safe temperature, it is proposed that a kind of can be used for is fixed cell bags and obtain the cell storage and conveying box and monitoring system with displays temperature and implementing warning.
A kind of cell storage and conveying box, its feature is, including casing, case lid, equipped with the constant temp. box of coolant and multiple cell accumulating box, described constant temp. box is arranged at inside two relative medial walls, tank floor and the case lid of described casing, another two relative medial walls are provided with internal fixed mount, multiple described cell accumulating boxes are mutually closely set in the space of described constant temp. box and described internal fixed mount composition, are all placed with cell bags in multiple described cell accumulating boxes.
In this programme, by arranging multiple cell accumulating box and cell bags being respectively put in a cell accumulating box, and fix the plurality of cell accumulating box by internal fixed mount and constant temp. box, make cell bags shockproof anti-shake dynamic, and maintain the temperature environment of described cell bags, there is bigger practicality.
It is preferred that be formed with space between described internal fixed mount and described cell accumulating box, being filled with padded coaming in described space, described padded coaming is sponge or bipeltate.
By filling padded coaming in space between internal fixed mount and described cell accumulating box further, further increase shockproof and anti-shake kinetic force.
It is preferred that be provided with a hollow insulating layer between the outer wall of described casing and inwall, between outer wall and the inwall of described case lid, it is provided with a hollow insulating layer.
By arranging hollow insulating layer between the inwall of casing and case lid, outer wall, cell bags inner cell can be extended further by this hollow insulating layer and be in the time of safe temperature.
Latch components is used to be connected it is preferred that be arranged at the described constant temp. box inside described case lid with described case lid.
Preferably, described cell storage and conveying box includes ECU, described ECU includes MCU (Micro Control Unit, micro-control unit), temperature sensor, alarm module, remote interaction module, described temperature sensor, described alarm module, described remote interaction module all electrically connect with described MCU;
Described temperature sensor is for detecting the temperature in cell storage and conveying box to obtain temperature value, and described temperature value sends extremely described MCU;
Described MCU is used for receiving described temperature value, generates warning message when described temperature value is not in preset temperature range, and sends described warning message to described alarm module;
Described alarm module is for reporting to the police after receiving described warning message;
Described MCU is additionally operable to send to described remote interaction module the temperature value received, and described remote interaction module is sent out the described temperature value received.
In this programme, obtain the temperature value in cell storage and conveying box by temperature sensor monitor the temperature in cell storage and conveying box in real time and do not report to the police in preset temperature range at temperature value, the cell that can be effectively ensured in cell storage and conveying box is in safe temperature, enhances the practicality of cell storage and conveying box.
It is preferred that described ECU also includes that display module, described display module electrically connect with described MCU, described display module is used for showing described temperature value.
By the temperature value that display obtains in real time, user can understand the temperature in cell storage and conveying box in time.
It is preferred that described ECU also includes that locating module, described locating module electrically connect with described MCU, described locating module is for obtaining and record the positional information of described cell storage and conveying box, and sends described positional information to described MCU.
Can effectively be obtained the positional information of cell storage and conveying box by locating module, and be sent out by MCU and remote interaction module, user can receive this positional information to obtain the position of cell storage and conveying box in time.
It is preferred that described preset temperature range is 4 DEG C~10 DEG C.
A kind of monitoring system, its feature is, including some described cell storage and conveying boxes and remote monitoring unit, described remote monitoring unit is for receiving the temperature value that the ECU in described cell storage and conveying box sends, when remote monitoring unit judges that the described temperature value received is not in preset temperature range, described remote monitoring unit is reported to the police.
In this programme, the most remotely being obtained the temperature value that the remote interaction module in ECU sends by remote monitoring unit, the cell that can be effectively ensured in cell storage box is in safe temperature, it is ensured that the activity of cell.
Preferably, described ECU also includes locating module, described locating module is for obtaining and record the positional information of described cell storage and conveying box, remote monitoring unit is additionally operable to receive the described positional information that described ECU sends, when remote monitoring unit judges that the described positional information received does not meets preset position information, described remote monitoring unit is reported to the police.
In this programme, remote monitoring unit obtains the positional information that ECU sends in real time, can determine the position of cell storage and conveying box timely and effectively.
On the basis of meeting common sense in the field, above-mentioned each optimum condition, can combination in any, obtain the preferred embodiments of the invention.
The actively progressive effect of the present invention is: the present invention can effectively prevent vibrations that the cell bags of accumulating is bigger and rock to cause the breakage of cell bags or the defect causing cytoactive to reduce, and monitor cell storage and conveying box inner cell or the temperature of cell bags local environment or positional information in real time, when the positional information of the temperature value in cell storage and conveying box or cell storage and conveying box occurs abnormal alarm, user can adopt an effective measure in time, enhances the practicality of cell storage and conveying box.
Accompanying drawing explanation
Fig. 1 is the contour structures schematic diagram of the cell storage and conveying box of one embodiment of the invention.
Fig. 2 is the cell storage and conveying box casing plan structure schematic diagram of one embodiment of the invention.
Fig. 3 is the decomposition texture schematic diagram of Fig. 1.
Fig. 4 is the cell storage and conveying box case lid snap close theory structure schematic diagram with constant temp. box of one embodiment of the invention.
Fig. 5 be one embodiment of the invention cell storage and conveying box in the structural representation of ECU.
Fig. 6 is the structural representation of the monitoring system including a cell storage and conveying box of one embodiment of the invention.
Fig. 7 is the structural representation of the monitoring system including multiple cell storage and conveying box of one embodiment of the invention.
Detailed description of the invention
Further illustrate the present invention below by the mode of embodiment, but the most therefore limit the present invention among described scope of embodiments.
As shown in Figures 1 to 4, a kind of cell storage and conveying box 1, including casing 11, case lid 12, constant temp. box 13 and multiple cell accumulating box 14 equipped with coolant, described cell storage and conveying box 1 is cuboid cell storage and conveying box, constant temp. box 12 is arranged at 11 liang of relative medial walls of described casing, inside casing 11 bottom surface and case lid, another two relative medial walls are provided with internal fixed mount 17, multiple described cell accumulating boxes 14 are mutually closely set in the space of described constant temp. box 13 and described internal fixed mount 17 composition, cell bags all it is placed with in multiple described cell accumulating boxes 14, cell bags is used for storing cell.
In this programme, the limit, two opposite sides of internal fixed mount 17 is hierarchic structure, the limit, two opposite sides of this inside fixed mount 17 props up the dual-side of cell accumulating box 14, the pars intermedia of internal fixed mount 17 forms space 16 with the end face of cell accumulating box 14, it is filled with padded coaming in this space 16, this padded coaming is sponge or bipeltate, and the type of padded coaming is not limited to this.
The locating piece 123 of two cuboids it is provided with on the inwall of case lid 12, between two locating pieces 123, it is provided with a cylinder fixes axle 122, described cylinder is fixed and is relatively provided with 3 positioning bars 1221 on axle 122, described positioning bar 1221 is provided with barb assembly, and this case lid 12 also includes latch components 121.
Described constant temp. box 13 is provided with two rectangular through holes 131, a manhole 132 it is provided with between two cuboid through holes 131, described manhole 132 sidewall is reciprocal latch structure, when the cylinder that the manhole 132 of constant temp. box 13 snaps in case lid 12 is fixed on axle 122, locating piece 123 agrees with hole 131, location, reciprocal latch structure and 3 positioning bars 1221 are fixed, finally, latch components 121 is agreed with 3 positioning bars 1221, and rotate described latch components 121 and make the barb assembly on positioning bar 1221 be fixed with described latch components 121, described constant temp. box 13 can be fixed.When taking out described constant temp. box 13, described in counter-rotating, latch components 121, i.e. can be taken off, and has both been easy to the fixing of constant temp. box 13, has also allowed for taking off described constant temp. box 13 at any time and the coolant in described constant temp. box 13 is carried out pre-refrigeration.Convenient and practical.
In sum, this cell storage and conveying box 1 can effectively fix cell bags, and can provide the temperature of short time, the shockproof anti-shake requirement such as dynamic for the active somatic cell in cell bags, has certain impact property, convenient and practical.
As shown in Figure 5, this cell storage and conveying box 1 also includes ECU, this ECU includes alarm module 101, display module 102, temperature sensor 103, locating module 104, remote interaction module 105 and MCU106, and alarm module 101, temperature sensor 103, remote interaction module 105, locating module 104, display module 102 all electrically connect with MCU106.
Temperature sensor 103 is for detecting the temperature in cell storage and conveying box 1 to obtain temperature value, and by described temperature value transmission to MCU106.
Locating module 104 is for obtaining and record the positional information of described cell storage and conveying box 1, and sends described positional information to MCU106.
MCU106 receives described temperature value and described positional information and described temperature value is sent to display module 102 shows, display module 102 is LCDs, simultaneously, by remote interaction module 105, described temperature value and described positional information are sent out, this remote interaction module 105 is GPRS (General Packet Radio Service, general packet radio service technology) communication module.Above-mentioned MCU106 can be FPGA (Field Programmable Gate Array, field programmable gate array) chip, DSP (Digital Signal Processor, digital signal processor) chip or flush bonding processor.
It addition, display module 102 is additionally operable to show temporal information, when cell bags is positioned in cell storage box 1, MCU106 starts timing and shows on display module 102, and accumulating personnel can obtain the temporal information of the display on display module 102 at any time.
In addition, MCU106 judges that the temperature value received is whether in the preset temperature range 4 DEG C~10 DEG C of safety, if not, MCU106 generates warning message and sends described warning message to alarm module 101, alarm module 101 is reported to the police after receiving described warning message, reminds accumulating personnel to implement emergency preplan targetedly.Temperature sensor 103 is arranged in cell storage and conveying box 1 in the space placing cell accumulating box 14, as it is shown on figure 3, notch 111 is opened on the outer wall of cell storage and conveying box 1, display module 102 is embedded in notch 111.
As shown in Figure 6, the present embodiment also provides for a kind of monitoring system, this monitoring system includes cell storage and conveying box 1 and a remote monitoring unit 2, this remote monitoring unit 2 is for receiving temperature value, temporal information and the positional information that the ECU in cell storage box 1 sends, when remote monitoring unit 2 judge the described temperature value that receives not in preset temperature range, temporal information not in preset time range or when positional information is unsatisfactory for preset position information, remote monitoring unit 2 is reported to the police.Preset temperature range is 4 DEG C~10 DEG C, preset time range is the safe storage time ensureing cytoactive, this safe storage time is 8 hours~10 hours, preset position information refers to the position of cell storage and conveying box 1 set in advance, when cell storage and conveying box 1 does not meets preset position information by the positional information that locating module 104 obtains, remote monitoring unit 2 is reported to the police, and reminds accumulating personnel to be tracked.
This remote monitoring unit 2 is computer, and this computer is for storing the temporal information of cell storage and conveying box 1, temperature value and the positional information of remotely acquisition.
As it is shown in fig. 7, this monitoring system can also include multiple cell storage and conveying box 1 and a remote monitoring unit 2, each cell storage and conveying box 1 is equipped with different numberings, and remote monitoring unit 2 determines the cell storage and conveying box 1 carrying out data interaction according to different numberings.
Although the foregoing describing the detailed description of the invention of the present invention, it will be appreciated by those of skill in the art that these are merely illustrative of, protection scope of the present invention is defined by the appended claims.These embodiments, on the premise of without departing substantially from the principle of the present invention and essence, can be made various changes or modifications, but these changes and amendment each fall within protection scope of the present invention by those skilled in the art.

Claims (10)

1. a cell storage and conveying box, it is characterised in that include casing, case lid, constant temperature equipped with coolant Box and multiple cell accumulating box, described constant temp. box is arranged at two relative medial wall, casings of described casing Inside bottom surface and case lid, another two relative medial walls are provided with internal fixed mount, multiple described cell accumulatings Box is mutually closely set in the space that described constant temp. box and described internal fixed mount are constituted, multiple described carefully Cell bags all it is placed with in born of the same parents' accumulating box.
2. cell storage and conveying box as claimed in claim 1, it is characterised in that described internal fixed mount with It is formed with space between described cell accumulating box, in described space, is filled with padded coaming, described buffering Material is sponge or bipeltate.
3. cell storage and conveying box as claimed in claim 1, it is characterised in that the outer wall of described casing with It is provided with a hollow insulating layer between inwall, between outer wall and the inwall of described case lid, is provided with a hollow insulating layer.
4. cell storage and conveying box as claimed in claim 1, it is characterised in that be arranged in described case lid The described constant temp. box of side uses latch components to be connected with described case lid.
5. the cell storage and conveying box as described in any one in Claims 1-4, it is characterised in that institute State cell storage and conveying box and include that ECU, described ECU include MCU, temperature sensor, warning Module, remote interaction module, described temperature sensor, described alarm module, described remote interaction module All electrically connect with described MCU;
Described temperature sensor is for detecting the temperature in cell storage and conveying box to obtain temperature value, and by described Temperature value sends to described MCU;
Described MCU is used for receiving described temperature value, when described temperature value is not in preset temperature range Generate warning message, and described warning message is sent to described alarm module;
Described alarm module is for reporting to the police after receiving described warning message;
Described MCU is additionally operable to send to described remote interaction module the temperature value that receives, described far Journey interactive module is sent out the described temperature value received.
6. cell storage and conveying box as claimed in claim 5, it is characterised in that described ECU also wraps Including display module, described display module electrically connects with described MCU, and described display module is used for showing institute State temperature value.
7. cell storage and conveying box as claimed in claim 5, it is characterised in that described ECU also wraps Including locating module, described locating module electrically connects with described MCU, and described locating module is for obtaining also Record the positional information of described cell storage and conveying box, and described positional information is sent to described MCU.
8. cell storage and conveying box as claimed in claim 5, it is characterised in that described preset temperature range It it is 4 DEG C~10 DEG C.
9. a monitoring system, it is characterised in that include some such as claim 5 to 8 any one Described cell storage and conveying box and remote monitoring unit, described remote monitoring unit is used for receiving the storage of described cell The temperature value that ECU in fortune case sends, when the described temperature value that remote monitoring unit judgement receives Time not in preset temperature range, described remote monitoring unit is reported to the police.
10. monitoring system as claimed in claim 9, it is characterised in that described ECU also includes Locating module, described locating module is for obtaining and record the positional information of described cell storage and conveying box, remotely Monitoring unit is additionally operable to receive the described positional information that described ECU sends, when remote monitoring unit is sentenced When the described positional information that disconnecting receives does not meets preset position information, described remote monitoring unit is reported to the police.
CN201510979134.7A 2015-12-22 2015-12-22 Cell storage and conveying box and monitoring system Active CN105857931B (en)

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CN105857931B CN105857931B (en) 2019-06-28

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CN110077704A (en) * 2019-03-22 2019-08-02 重庆懿熙品牌策划有限公司 A kind of monitoring system and its logistics guard box
US20200182527A1 (en) * 2018-12-06 2020-06-11 Tcp Reliable, Inc. Thermal insulation box with cooling mechanism
US10899529B2 (en) * 2018-12-06 2021-01-26 Integreon Global, Inc. Thermal insulation box with temperature and humidity sensors
CN113978924A (en) * 2021-11-09 2022-01-28 浙江优纳特科学仪器有限公司 GSP intelligent transportation storage box and control method thereof

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US20200182527A1 (en) * 2018-12-06 2020-06-11 Tcp Reliable, Inc. Thermal insulation box with cooling mechanism
US10899529B2 (en) * 2018-12-06 2021-01-26 Integreon Global, Inc. Thermal insulation box with temperature and humidity sensors
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