CN105852896A - Low-dosage spiral CT scanning method for PET/MRI (positron emission tomography/magnetic resonance imaging) lung examination - Google Patents
Low-dosage spiral CT scanning method for PET/MRI (positron emission tomography/magnetic resonance imaging) lung examination Download PDFInfo
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- CN105852896A CN105852896A CN201610176570.5A CN201610176570A CN105852896A CN 105852896 A CN105852896 A CN 105852896A CN 201610176570 A CN201610176570 A CN 201610176570A CN 105852896 A CN105852896 A CN 105852896A
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- 238000002591 computed tomography Methods 0.000 title claims abstract description 48
- 238000000034 method Methods 0.000 title claims abstract description 26
- 210000004072 lung Anatomy 0.000 title claims abstract description 18
- 238000002595 magnetic resonance imaging Methods 0.000 title abstract description 41
- 238000012879 PET imaging Methods 0.000 title abstract 8
- 238000002600 positron emission tomography Methods 0.000 title abstract 2
- 230000004927 fusion Effects 0.000 claims abstract description 12
- 239000003814 drug Substances 0.000 claims abstract description 6
- 238000007689 inspection Methods 0.000 claims description 22
- 230000002685 pulmonary effect Effects 0.000 claims description 19
- 238000002347 injection Methods 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 238000002955 isolation Methods 0.000 claims description 5
- 238000001514 detection method Methods 0.000 abstract description 15
- 238000003745 diagnosis Methods 0.000 abstract description 10
- 230000003902 lesion Effects 0.000 abstract description 8
- 230000035945 sensitivity Effects 0.000 abstract description 5
- AOYNUTHNTBLRMT-SLPGGIOYSA-N 2-deoxy-2-fluoro-aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O AOYNUTHNTBLRMT-SLPGGIOYSA-N 0.000 abstract 2
- 208000000017 Solitary Pulmonary Nodule Diseases 0.000 abstract 2
- 238000012636 positron electron tomography Methods 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 11
- 206010028980 Neoplasm Diseases 0.000 description 2
- 238000013399 early diagnosis Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000004904 shortening Methods 0.000 description 2
- 208000018152 Cerebral disease Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 208000019155 Radiation injury Diseases 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000005337 ground glass Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/027—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis characterised by the use of a particular data acquisition trajectory, e.g. helical or spiral
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
- A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
- A61B6/5235—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
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Abstract
The invention relates to a low-dosage spiral CT scanning method for PET/MRI (positron emission tomography/magnetic resonance imaging) lung examination, wherein the examination method comprises the following steps: (1) before injecting FDG (fluorodeoxyglucose) drugs, conducting low-dosage spiral CT scanning; (2) conducting target scanning when an SPN (solitary pulmonary nodule) is discovered in a lung; (3) after scanning, implementing PET/MRI examination, wherein the low-dosage spiral scanning is completed on multiple rows of spiral CT machines; and (4) after the PET/MRI scanning, promoting heterogeneous fusion between spiral CT scanning data and a PET image in PET/MRI. With the adoption of the low-dosage spiral CT scanning method for PET/MRI lung examination disclosed by the invention, chest minimum lesions can be detected as soon as possible, and with coordinated application, intrapulmonaray lesion detection sensitivity and accuracy of PET/MRI scanning are obviously improved to 95% and 84%; and especially, through the heterogeneous fusion between the spiral CT scanning data and the PET data in the PET/MRI, the qualitative diagnosis capacity of detecting focuses by spiral CT scanning is further improved.
Description
Technical field
The present invention relates to medical domain, particularly relate to the using method of low-dose spiral CT, specifically refer to a kind of low dosage spiral
CT scan is for the inspection method of PET/MRI pulmonary.
Background technology
PET/MRI checks and compares with conventional PET/CT, and radiating the damage to human body can significantly lower, because unlike CT,
MRI to human body without any radiation injury.Excessively CT examination may cause cancer.Therefore, PET/MRI be optimal health check-up and
Diagnostic device.PET/MRI check compared with other means, it highly sensitive, accuracy good, to numerous disease (especially
Tumor and most commonly seen cardio-cerebral diseases) there is the value of early discovery, early diagnosis.
Low-dose spiral CT can increase (non-calcified tuberosity is drawn in calcification) non-calcified tuberosity and bronchus morbidity (disease) in lung
Recall rate, early diagnosis pulmonary carcinoma is had important value.PET/MRI because of the feature of its image-forming principle, for except pulmonary lesion it
Outer each system has obvious detection advantage, and recall rate can improve 15% by relatively PET/CT.But unquestionable, PET/MRI is at chest
Truly have short slab in the detection usefulness of minute lesion, as in lung, ground glass focus and inflammatory lesions are the most likely failed to pinpoint a disease in diagnosis, thus give patient
Bring unpredictable serious consequence or cause medical treatment potential risk to center.Therefore it is badly in need of one and can assist raising detection usefulness
Detection method to improve detection efficiency, the most accurately detect whether that there is chest minute lesion.
Summary of the invention
It is an object of the invention to the shortcoming overcoming above-mentioned prior art, it is provided that a kind of low dosage spiral that can improve recall rate
CT scan is for the inspection method of PET/MRI pulmonary, and applies multifunctional workstation, by Spiral CT scan data with
PET image in PET/MRI carries out different machine fusion, to improve the etiologic diagnosis for Spiral CT scan detection focus further
Ability.
To achieve these goals, the Low-dose Spiral CT Scan of the present invention for the inspection method of PET/MRI pulmonary have as
Lower composition:
This Low-dose Spiral CT Scan is for the inspection method of PET/MRI pulmonary, and it is mainly characterized by, described low dosage spiral shell
Rotation CT scan includes for the inspection method of PET/MRI pulmonary:
(1) before injection FDG medicine, Low-dose Spiral CT Scan is carried out；
(2) scanning finds there is isolation degree SPN in lung, carry out target scan；
(3) PET/MRI inspection is carried out after the end of scan；
(4) after the PET/MRI end of scan, SIMENS SYNGO.VIA multifunctional workstation is applied, by spiral CT
Scan data carries out different machine fusion with the PET image in PET/MRI；
Wherein said low dose helical scan has scanned on multi-slices CT machine.
Preferably, described step (1) particularly as follows:
Before injection FDG medicine, carrying out Low-dose Spiral CT Scan, sweep parameter is 80～120KV, 20～60mAs,
Sweep limits is from apex pulmonis to the base of lung, and DLP is 63.4mGY cm, and radiological dose is 70.8mGY.
It is highly preferred that weight dose index is conventional sweep dosage the 25% of described Low-dose Spiral CT Scan.
It is further preferred that described routine dose DLP is 248mGY cm, milliampere-second is 3521mAs, and radiological dose is
274.7mGY。
It is further preferred that described step (2) particularly as follows:
Scanning finds have isolation degree SPN in lung, reduces DFOV, increase sweep parameter to 140～180Kv and 260mA
To carry out target scan.
Most preferably, described multifunctional workstation is SIMENS SYNGO.VIA multifunctional workstation.
Have employed the inspection method for PET/MRI pulmonary of the Low-dose Spiral CT Scan in this invention, can detect as soon as possible
Chest minute lesion, reduces the probability failed to pinpoint a disease in diagnosis, and improves the safety of detection, and applies the many merits of SIMENS SYNGO.VIA
Spiral CT scan data are carried out different machine fusion with the PET image in PET/MRI, can make after fit applications by energy work station
PET/MRI scanning detection lung inner disease foci sensitivity and accuracy significantly improve, and reach 95%, 84% respectively, the most just spiral
CT scan data carries out different machine fusion with the PET data in PET/MRI, detects for Spiral CT scan to improve further
The etiologic diagnosis ability of focus.Along with future PETMRI in clinical wide popularization and application, as mismatched application low dosage spiral shell
, more serious wrong diagnosis and escape risk can be there is in rotation CT scan, and novelty Low-dose Spiral CT Scan is integrated into PET/MRI
In inspection and carry out different machine fusion, sensitivity and the accuracy of detection lung inner disease foci can be significantly improved.Alleviate the misery of sufferer, and
Shortening detection process, substantially increase the recall rate of pulmonary's minimal disease, method is simple to operation, is suitable for large-scale promotion.
Detailed description of the invention
In order to more clearly describe the technology contents of the present invention, conduct further description below in conjunction with specific embodiment.
This Low-dose Spiral CT Scan is for the inspection method of PET/MRI pulmonary, and it is mainly characterized by, described low dosage spiral shell
Rotation CT scan includes for the inspection method of PET/MRI pulmonary:
(1) before injection FDG medicine, Low-dose Spiral CT Scan is carried out；Sweep parameter is 80～120KV, 20～
60mAs, sweep limits is from apex pulmonis to the base of lung, and DLP is 63.4mGY cm, and radiological dose is 70.8mGY.；Described low dose
Weight dose index is conventional sweep dosage the 25% of amount Spiral CT scan；Wherein said routine dose DLP is
248mGY cm, milliampere-second is 3521mAs (P ＜ 0.001), and radiological dose is 274.7mGY.
(2) scanning finds there is isolation degree SPN in lung, reduces DFOV, increase sweep parameter to 140～180Kv and
260mA is to carry out target scan；
(3) PET/MRI inspection is carried out after the end of scan；
(4) after the PET/MRI end of scan, SIMENS SYNGO.VIA multifunctional workstation is applied, by spiral CT
Scan data carries out different machine fusion with the PET image in PET/MRI, detects focus to improve further for Spiral CT scan
Etiologic diagnosis ability.
Wherein Low-dose Spiral CT Scan need not strengthen, and can scan and can complete on multi-slices CT machine.
Have employed the inspection method for PET/MRI pulmonary of the Low-dose Spiral CT Scan in this invention, can detect as soon as possible
Chest minute lesion, reduces the probability failed to pinpoint a disease in diagnosis, and improves the safety of detection, and applies the many merits of SIMENS SYNGO.VIA
Spiral CT scan data are carried out different machine fusion with the PET image in PET/MRI, can make after fit applications by energy work station
PET/MRI scanning detection lung inner disease foci sensitivity and accuracy significantly improve, and reach 95%, 84% respectively, the most just spiral
CT scan data carries out different machine fusion with the PET data in PET/MRI, detects for Spiral CT scan to improve further
The etiologic diagnosis ability of focus.Along with future PETMRI in clinical wide popularization and application, as mismatched application low dosage spiral shell
, more serious wrong diagnosis and escape risk can be there is in rotation CT scan, and novelty Low-dose Spiral CT Scan is integrated into PET/MRI
In inspection and carry out different machine fusion, sensitivity and the accuracy of detection lung inner disease foci can be significantly improved.Alleviate the misery of sufferer, and
Shortening detection process, substantially increase the recall rate of pulmonary's minimal disease, method is simple to operation, is suitable for large-scale promotion.
In this description, the present invention is described with reference to its specific embodiment.But it is clear that still may be made that various
Amendment and conversion are without departing from the spirit and scope of the present invention.Therefore, description is regarded in an illustrative, rather than a restrictive.
Claims (6)
1. a Low-dose Spiral CT Scan is for the inspection method of PET/MRI pulmonary, it is characterised in that described inspection
Method includes:
(1) before injection FDG medicine, Low-dose Spiral CT Scan is carried out；
(2) scanning finds there is isolation degree SPN in lung, directly carry out target scan；
(3) whole body PET/MRI inspection is carried out after the end of scan；
(4) after the PET/MRI end of scan, multifunctional workstation is applied, by Spiral CT scan data and PET/MRI
PET image carry out different machine fusion；
Wherein said low dose helical scan has scanned on multi-slices CT machine.
Low-dose Spiral CT Scan the most according to claim 1 is for the inspection method of PET/MRI pulmonary, its feature
Be, described step (1) particularly as follows:
Before injection FDG medicine, carrying out Low-dose Spiral CT Scan, sweep parameter is 80～120KV, 20～60mAs,
Sweep limits is from apex pulmonis to the base of lung, and DLP is 63.4mGY cm, and radiological dose is 70.8mGY.
Low-dose Spiral CT Scan the most according to claim 2 is for the inspection method of PET/MRI pulmonary, its feature
It is, weight dose index is conventional sweep dosage the 25% of described Low-dose Spiral CT Scan.
Low-dose Spiral CT Scan the most according to claim 3 is for the inspection method of PET/MRI pulmonary, its feature
Being, described routine dose DLP is 248mGY cm, and milliampere-second is 3521mAs, and radiological dose is 274.7mGY.
Low-dose Spiral CT Scan the most according to claim 1 is for the inspection method of PET/MRI pulmonary, its feature
Be, described step (2) particularly as follows:
Scanning finds have isolation degree SPN in lung, reduces DFOV, increase sweep parameter to 140～180Kv and 260mA
To carry out target scan.
Low-dose Spiral CT Scan the most according to claim 1 is for the inspection method of PET/MRI pulmonary, its feature
Being, described multifunctional workstation is SIMENS SYNGO.VIA multifunctional workstation.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108389240A (en) * | 2018-02-28 | 2018-08-10 | 天津市肿瘤医院 | A method of low radiation dose Lung neoplasm screening is carried out using image omics technology |
| CN110547823A (en) * | 2019-08-21 | 2019-12-10 | 江南大学附属医院（无锡市第四人民医院） | Low-dose CT perfusion scanning imaging system |
| CN110664425A (en) * | 2019-10-11 | 2020-01-10 | 上海市肺科医院 | Key CT technology of lung in-situ cancer identification method |
-
2016
- 2016-03-25 CN CN201610176570.5A patent/CN105852896A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108389240A (en) * | 2018-02-28 | 2018-08-10 | 天津市肿瘤医院 | A method of low radiation dose Lung neoplasm screening is carried out using image omics technology |
| CN108389240B (en) * | 2018-02-28 | 2021-08-13 | 天津市肿瘤医院 | Method for screening low-radiation-dose pulmonary nodules by adopting imaging omics technology |
| CN110547823A (en) * | 2019-08-21 | 2019-12-10 | 江南大学附属医院（无锡市第四人民医院） | Low-dose CT perfusion scanning imaging system |
| CN110664425A (en) * | 2019-10-11 | 2020-01-10 | 上海市肺科医院 | Key CT technology of lung in-situ cancer identification method |
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