CN105816762A - 一种治疗气滞血瘀型子宫腺肌病的中药组合物 - Google Patents

一种治疗气滞血瘀型子宫腺肌病的中药组合物 Download PDF

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CN105816762A
CN105816762A CN201610309995.9A CN201610309995A CN105816762A CN 105816762 A CN105816762 A CN 105816762A CN 201610309995 A CN201610309995 A CN 201610309995A CN 105816762 A CN105816762 A CN 105816762A
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Abstract

本发明公开了一种治疗气滞血瘀型子宫腺肌病的中药组合物，其特征是由下列重量配比的药材制成：扁秆藨草20份、草血竭15份、蛋不老25份、番红花3份、鬼箭羽8份、黑三棱8份、红梗草12份、金盏菊根40份、虎杖12份、刘寄奴8份、竹节参8份、雪山鼠尾草12份、茨菇草12份、灰栒子12份、芒萁40份、砖子苗20份、甘草8份。本发明的中药组合物，用于治疗气滞血瘀型子宫腺肌病，有效率高，疗效可靠，愈后不再复发。

Description

一种治疗气滞血瘀型子宫腺肌病的中药组合物
技术领域
本发明涉及一种中药，特别是一种用于治疗气滞血瘀型子宫腺肌病的中药组合物。
背景技术
子宫腺肌病是子宫内膜侵入子宫肌层引起的一种良性病变，为常见的妇科病。属于中医的"痛经"、"症瘕"、"月经过多"、"经期延长"等病的范畴。子宫腺肌病多继发于产后、人流、诊刮术后，多由于产后或术后，血室正开，正气虚损，寒邪乘虚客于胞中，寒凝血瘀；或内伤七情，肝郁气滞，血行不畅致血瘀；或肝郁脾虚，运化失职，水湿内停，肾阳虚，气化无力，致津液不化，聚湿成痰，痰阻气滞，与血相搏结。气滞、寒凝、痰湿均可致血瘀，瘀滞冲任胞中日久而成癥瘕；瘀血内阻，冲任失调，则月经量多，经期延长；气机不畅，不通则痛，故而痛经。典型症状是继发性痛经、进行性加重，月经量多，经期延长和子宫增大。目前，治疗子宫腺肌病的主要方法有：西医治疗、中医治疗、手术治疗、介入治疗。这些治疗方法各有千秋，而中医治疗是安全可靠的治疗方法，治疗效果好，治愈后不再复发。中医根据不同原因引起的子宫腺肌病，结合临床实际进行辨证治疗，将本病分为：气滞血瘀型、寒凝血瘀型、痰凝血瘀型。
发明内容
本发明的目的旨在提供一种治疗气滞血瘀型子宫腺肌病的中药组合物，通过选择合适的药材及其配比，达到安全有效治愈气滞血瘀型子宫腺肌病的目的。
为达到上述目的，本发明采用以下技术方案：一种治疗气滞血瘀型子宫腺肌病的中药组合物，其特征是由下列重量配比的药材制成：
扁秆藨草20份、草血竭15份、蛋不老25份、番红花3份、鬼箭羽8份、黑三棱8份、红梗草12份、金盏菊根40份、虎杖12份、刘寄奴8份、竹节参8份、雪山鼠尾草12份、茨菇草12份、灰栒子12份、芒萁40份、砖子苗20份、甘草8份。
配方中所涉及到的药材的来源及功能主治如下:
扁秆藨草【来源】药材基源：为莎草科植物扁秆藨草的块茎。【性味】味苦；性平【归经】肺；胃；肝经【功能主治】祛瘀通经；行气消积。主经闭；痛经；产后瘀阻腹痛；症瘕积聚；胸腹胁痛；消化不良。
草血竭【来源】药材基源：为蓼科植物草血竭的根茎。【性味】苦；辛；性寒【功能主治】散瘀止血；下气消积；消毒；利湿。主症瘕积聚；跌打损伤；外伤出血；吐血；咯血；衄血；经闭；崩漏；慢性胃炎；胃、十二指肠溃疡；食积停滞；痢疾；肠炎；水肿；疮毒；蛇咬伤；烫火伤。
蛋不老【来源】药材基源：为大戟科植物广东地构叶的全草。【性味】苦；平【归经】肺；肝；大肠经【功能主治】祛风湿；通经络；破瘀止痛。主风湿痹痛；症瘕积聚；瘰疬；疔疮肿毒；跌打损伤。
番红花【来源】药材基源：为鸢尾科植物番红花花柱的上部及柱头。【性味】甘；平【归经】心；肝经【功能主治】活血祛瘀；散郁开结；凉血解毒。主痛经；经闭；月经不调；产后恶露不净；腹中包块疼痛；跌扑损伤；忧郁痞闷；惊悸；温病发斑；麻疹。
鬼箭羽【来源】药材基源：为卫矛科植物卫矛的具翅状物的枝条或翅状附属物。【性味】苦；辛；寒【归经】肝经【功能主治】破血通经；解毒消肿；杀虫。主症瘕结块；心腹疼痛；闭经；痛经；崩中漏下；产后瘀滞腹痛；恶露不下；疝气；历节痹痛；疮肿；跌打伤痛；虫积腹痛；烫火伤；毒蛇咬伤。
黑三棱【来源】药材基源：为莎草科植物荆三棱的块茎。【性味】味辛；苦；性平【归经】肝；脾经【功能主治】祛瘀通经；破血消症；行气消积。主血滞经闭；痛经；产后瘀阻腹痛；跌打瘀肿；腹中包块；食积腹痛。
红梗草【来源】药材基源：为菊科植物异叶泽兰的全草.【性味】味甘；苦；性微温【归经】归肝；肾经【功能主治】活血调经；祛瘀止痛；除湿行水。主月经不调；经闭；症瘕；腹痛；产后恶露不行；小便淋漓；水肿；跌打损伤；骨折。
金盏菊根【来源】药材基源：为菊科植物金盏菊的根。【性味】味微苦；性平【功能主治】活血散瘀；行气止痛。主症瘕；疝气；胃寒疼痛。
虎杖【来源】药材基源：为蓼科植物虎杖的根茎及根。【性味】苦；酸；性微寒【归经】肝；胆经【功能主治】活血散瘀；祛风通络；清热利湿；解毒。主妇女经闭；痛经；产后恶露不下；症瘕积聚；跌扑损伤；风湿痹痛；湿热黄疸；淋浊带下；疮疡肿毒；毒蛇咬伤；水火烫伤。
刘寄奴【来源】药材基源：为菊科植物奇蒿的带花全草。【性味】味辛；微苦；性温【归经】归心；肝；脾经【功能主治】破瘀通经；止血消肿；消食化积。主经闭；‘痛经；产后瘀滞腹痛；恶露不尽，症瘕；跌打损伤；金疮出血；风湿痹痛；便血；尿血；痈疮肿毒；烫伤；食积腹痛；泄泻痢疾。
竹节参【来源】药材基源：为五加科植物竹节参的根茎。【性味】味甘；微苦；性微温【归经】归肺；脾；肝经【功能主治】补虚强壮；止咳祛痰；散瘀止血；消肿止痛。主病后体弱；食欲不振；虚劳咳嗽；咯血；吐血；衄血；便血；尿血；倒经；崩漏；外伤出血；症瘕；瘀血经闭；产后瘀阴腹痛；跌打损伤；风湿关节痛；痈肿；痔疮；毒蛇咬伤。
雪山鼠尾草【来源】药材基源：为唇形科植物雪山鼠尾草的根。【性味】味苦；性微寒【功能主治】活血化瘀；消肿止痛。主月经不调；痛经；经闭；瘀血腹痛；崩漏；症瘕；瘰疬；红疹；跌打损伤；漆疮。
茨菇草【来源】药材基源：为禾本科植物箭叶大油芒的全草。【性味】味淡；性平【归经】肝经【功能主治】调经；催产；行气。主月经过多；难产；胸闷；气胀。
灰栒子【来源】药材基源：为蔷薇科植物灰栒子的枝叶及果实。【性味】苦、涩；凉【归经】肝经【功能主治】凉血止血，解毒敛疮。主鼻衄；牙龈出血；月经过多。
芒萁【来源】蕨类里白科芒萁属植物芒萁Dicranopterisdichotoma（Thunb.）Bernh.以全草或根状茎入药。四季可采，鲜用或晒干。【性味】苦、涩，平。【功能主治】清热利尿，化瘀，止血。用于鼻衄，肺热咳血，尿道炎，膀胱炎，小便不利，水肿，月经过多，血崩，白带；外用治创伤出血，跌打损伤，烧烫伤，骨折，蜈蚣咬伤。
砖子苗【来源】药材基源：为莎草科植物砖子苗的全草。【性味】味辛；微苦；性平【归经】肺经【功能主治】祛风解表；止咳化痰；解郁调经。主风寒感冒；咳嗽痰多；皮肤瘙痒；月经不调。
甘草【来源】本品为豆科植物甘草、胀果甘草或光果甘草的干燥根。【性味】甘，平。【归经】归心、肺、脾、胃经。【功能主治】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
在中医辨证治疗的过程中，我们通常可以结合阴道超声检查、影像学检查等进一步确诊。气滞血瘀型子宫腺肌病临床表现为经期小腹胀痛或痉挛性疼痛，剧烈拒按，心烦易怒，胸胁乳房胀痛，月经量多，有块，或经行时间延长，子宫增大，舌质紫，或有瘀点，脉弦涩。本发明将这些药材有机的组合在一起，各种药物相互配合，协合作用，所制得的中药具有活血调经，祛瘀止痛，兼以行气、解郁、凉血止血的功效，对治疗气滞血瘀型子宫腺肌病，具有十分显著的疗效。
下面给合临床实验数据说明本发明的有益效果：
1、一般资料：
发明人2009年1月份2012年12月间共收集了60例确诊为气滞血瘀型子宫腺肌病的患者，年龄在27-40岁，病程2-13个月。随机分组为：治疗组为40例，空白组20例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法：
2.1治疗组口服本发明按照具体实施例1制得的胶囊，一日3次。疗程2个月。
2.2空白组口服妇女痛经丸,一日3次。疗程2个月。
3、疗效标准与治疗效果：
3．1疗效标准
临床痊愈：气滞血瘀型子宫腺肌病的临床症状、体征消失；好转：气滞血瘀型子宫腺肌病的临床症状、体征明显改善；无效：气滞血瘀型子宫腺肌病的临床症状、体征均无明显改善或加重。
3．2治疗统计结果见表1。
表1两组疗效比较
组别 n 痊愈 好转 无效 总有效率（%）
治疗组 40 6 30 4 90%
空白组 20 4 9 7 65%
可见本发明的中药能够安全有效地治疗气滞血瘀型子宫腺肌病。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1：
称取扁秆藨草20克、草血竭15克、蛋不老25克、番红花3克、鬼箭羽8克、黑三棱8克、红梗草12克、金盏菊根40克、虎杖12克、刘寄奴8克、竹节参8克、雪山鼠尾草12克、茨菇草12克、灰栒子12克、芒萁40克、砖子苗20克、甘草8克，加8倍量水，煎煮1.5小时，过滤，滤渣加6倍量水，煎煮1小时，过滤，合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人3天用量的胶囊剂。
用于治疗气滞血瘀型子宫腺肌病，口服，每日早、中、晚三次服用。
具体实施例2：
称取扁秆藨草20克、草血竭15克、蛋不老25克、番红花3克、鬼箭羽8克、黑三棱8克、红梗草12克、金盏菊根40克、虎杖12克、刘寄奴8克、竹节参8克、雪山鼠尾草12克、茨菇草12克、灰栒子12克、芒萁40克、砖子苗20克、甘草8克，加10倍量水，煎煮2小时，过滤，滤渣加8倍量水，煎煮1.5小时，过滤，合并滤液，浓缩，干燥，包装，即得符合正常成人3天用量的散剂。
用于治疗气滞血瘀型子宫腺肌病，口服，每日早、中、晚三次服用。
具体实施例3：
称取扁秆藨草20克、草血竭15克、蛋不老25克、番红花3克、鬼箭羽8克、黑三棱8克、红梗草12克、金盏菊根40克、虎杖12克、刘寄奴8克、竹节参8克、雪山鼠尾草12克、茨菇草12克、灰栒子12克、芒萁40克、砖子苗20克、甘草8克，加8倍量水，煎煮1.5小时，过滤，滤渣加6倍量水，煎煮1.5小时，过滤，合并滤液，浓缩，干燥，再加入适量糊精与矫味剂,按照本领域常规工艺制粒,包装,即可制得符合正常成人3天用量的颗粒剂。
用于治疗气滞血瘀型子宫腺肌病，口服，每日早、中、晚三次服用。

Claims (1)

1.一种治疗气滞血瘀型子宫腺肌病的中药组合物，其特征是由下列重量配比的药材制成：扁秆藨草20份、草血竭15份、蛋不老25份、番红花3份、鬼箭羽8份、黑三棱8份、红梗草12份、金盏菊根40份、虎杖12份、刘寄奴8份、竹节参8份、雪山鼠尾草12份、茨菇草12份、灰栒子12份、芒萁40份、砖子苗20份、甘草8份。
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