CN105815784A - Method for preparing double-wall-layer fresh ginger volatile oil microcapsules - Google Patents
Method for preparing double-wall-layer fresh ginger volatile oil microcapsules Download PDFInfo
- Publication number
- CN105815784A CN105815784A CN201610180492.6A CN201610180492A CN105815784A CN 105815784 A CN105815784 A CN 105815784A CN 201610180492 A CN201610180492 A CN 201610180492A CN 105815784 A CN105815784 A CN 105815784A
- Authority
- CN
- China
- Prior art keywords
- volatile oil
- zingiberis recens
- preparation
- rhizoma dioscoreae
- rhizoma zingiberis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000341 volatile oil Substances 0.000 title claims abstract description 48
- 239000003094 microcapsule Substances 0.000 title claims abstract description 27
- 241000234314 Zingiber Species 0.000 title abstract description 12
- 235000006886 Zingiber officinale Nutrition 0.000 title abstract description 11
- 235000008397 ginger Nutrition 0.000 title abstract description 11
- 238000000034 method Methods 0.000 title abstract description 10
- 239000000463 material Substances 0.000 claims abstract description 28
- 238000002360 preparation method Methods 0.000 claims abstract description 21
- 239000000725 suspension Substances 0.000 claims abstract description 16
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 6
- 238000001694 spray drying Methods 0.000 claims abstract description 3
- 229920002472 Starch Polymers 0.000 claims description 51
- 239000008107 starch Substances 0.000 claims description 51
- 235000019698 starch Nutrition 0.000 claims description 51
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 27
- 150000002148 esters Chemical class 0.000 claims description 25
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 18
- 102000004190 Enzymes Human genes 0.000 claims description 17
- 108090000790 Enzymes Proteins 0.000 claims description 17
- 229940088598 enzyme Drugs 0.000 claims description 17
- 239000000243 solution Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 12
- 238000005406 washing Methods 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 108010010803 Gelatin Proteins 0.000 claims description 7
- 229920002774 Maltodextrin Polymers 0.000 claims description 7
- 239000005913 Maltodextrin Substances 0.000 claims description 7
- 229920000159 gelatin Polymers 0.000 claims description 7
- 239000008273 gelatin Substances 0.000 claims description 7
- 235000019322 gelatine Nutrition 0.000 claims description 7
- 235000011852 gelatine desserts Nutrition 0.000 claims description 7
- 229940035034 maltodextrin Drugs 0.000 claims description 7
- 235000010489 acacia gum Nutrition 0.000 claims description 6
- 239000001785 acacia senegal l. willd gum Substances 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 239000012153 distilled water Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 235000013336 milk Nutrition 0.000 claims description 6
- 239000008267 milk Substances 0.000 claims description 6
- 210000004080 milk Anatomy 0.000 claims description 6
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims description 5
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 5
- 108010073771 Soybean Proteins Proteins 0.000 claims description 5
- 102000004139 alpha-Amylases Human genes 0.000 claims description 5
- 108090000637 alpha-Amylases Proteins 0.000 claims description 5
- 229940024171 alpha-amylase Drugs 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 235000010445 lecithin Nutrition 0.000 claims description 5
- 239000000787 lecithin Substances 0.000 claims description 5
- 229940067606 lecithin Drugs 0.000 claims description 5
- 235000019710 soybean protein Nutrition 0.000 claims description 5
- 238000007602 hot air drying Methods 0.000 claims description 4
- 239000007981 phosphate-citrate buffer Substances 0.000 claims description 4
- FYKDNWHPKQOZOT-UHFFFAOYSA-M sodium;dihydrogen phosphate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].OP(O)([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O FYKDNWHPKQOZOT-UHFFFAOYSA-M 0.000 claims description 4
- -1 sucrose ester Chemical class 0.000 claims description 4
- 229920001661 Chitosan Polymers 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 235000010418 carrageenan Nutrition 0.000 claims description 3
- 239000000679 carrageenan Substances 0.000 claims description 3
- 229920001525 carrageenan Polymers 0.000 claims description 3
- 229940113118 carrageenan Drugs 0.000 claims description 3
- 239000007766 cera flava Substances 0.000 claims description 3
- 230000009514 concussion Effects 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 238000000194 supercritical-fluid extraction Methods 0.000 claims description 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 3
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 2
- 229920000858 Cyclodextrin Polymers 0.000 claims description 2
- 229920001214 Polysorbate 60 Polymers 0.000 claims description 2
- NWGKJDSIEKMTRX-MDZDMXLPSA-N Sorbitan oleate Chemical compound CCCCCCCC\C=C\CCCCCCCC(=O)OCC(O)C1OCC(O)C1O NWGKJDSIEKMTRX-MDZDMXLPSA-N 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 2
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims description 2
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims description 2
- 229940113124 polysorbate 60 Drugs 0.000 claims description 2
- 229920000053 polysorbate 80 Polymers 0.000 claims description 2
- 239000002244 precipitate Substances 0.000 claims description 2
- 230000004044 response Effects 0.000 claims description 2
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims description 2
- 235000010413 sodium alginate Nutrition 0.000 claims description 2
- 239000000661 sodium alginate Substances 0.000 claims description 2
- 229940005550 sodium alginate Drugs 0.000 claims description 2
- 239000008347 soybean phospholipid Substances 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
- 238000010298 pulverizing process Methods 0.000 claims 1
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
- 235000013305 food Nutrition 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 2
- 230000008014 freezing Effects 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 238000000265 homogenisation Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 6
- 239000000843 powder Substances 0.000 description 5
- 150000008064 anhydrides Chemical class 0.000 description 3
- 230000033228 biological regulation Effects 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229960004756 ethanol Drugs 0.000 description 3
- 239000008601 oleoresin Substances 0.000 description 3
- 238000001556 precipitation Methods 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000011162 core material Substances 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- KCYQMQGPYWZZNJ-BQYQJAHWSA-N hydron;2-[(e)-oct-1-enyl]butanedioate Chemical compound CCCCCC\C=C\C(C(O)=O)CC(O)=O KCYQMQGPYWZZNJ-BQYQJAHWSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229960000935 dehydrated alcohol Drugs 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 239000010649 ginger oil Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000013622 meat product Nutrition 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 125000004365 octenyl group Chemical group C(=CCCCCCC)* 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000003578 releasing effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicinal Preparation (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
The invention relates to a method for preparing double-wall fresh ginger volatile oil microcapsules.The method includes the steps that fresh ginger volatile oil is dispersed in an inner layer wall material and homogenized at normal temperature and high pressure, and a primary suspension is prepared; secondly, the primary suspension is dispersed in an outer layer wall material, emulsifier is added, the primary suspension is homogenized at normal temperature and high pressure, and a secondary suspension is obtained; thirdly, the secondary suspension is dried, and the double-wall fresh ginger volatile oil microcapsules are obtained.The embedding rate of the prepared fresh ginger microcapsules is 81-98%, in the preparation process, the technology that fresh ginger volatile oil is supercritically extracted and normal-temperature double-layer embedding, high-pressure homogenization and freezing or spray drying are conducted is adopted, so that the product embedding rate is high, the embedding effect is good, flowability is good, stability of effective components of the fresh ginger volatile oil can be improved, bioavailability is high, and the method is used in the food and health-care product field.
Description
Technical field
The invention belongs to food micro capsule embedding techniques field, relate to Rhizoma Zingiberis Recens volatile oil microcapsule, especially a kind of
The preparation method of Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule.
Background technology
Rhizoma Zingiberis Recens system Zingiberaceae ginger, has many health cares and medicinal function, is the Chinese medicine of wide clinical application,
Rhizoma Zingiberis Recens has pharmacologically active widely to cardio-cerebrovascular, digestive system, immune system and nervous system etc..Existing
Show for pharmaceutical research, the effective ingredient ginger oil resin of Rhizoma Zingiberis Recens and volatile oil have anticoagulant, boosting, blood fat reducing,
Many pharmacological actions such as antiinflammatory, function of gallbladder promoting protect the liver, are eaten for a long time Rhizoma Zingiberis Recens and have certain regulation blood fat, prevention
Thrombosis and atherosclerosis etc. act on.It addition, Rhizoma Zingiberis Recens volatile oil is fragrance and the part local flavor of Rhizoma Zingiberis Recens
Source, this transparent pale yellow or orange liquid has strong aromatic odor, can be as fumet and wind
Taste agent is for the processing of the numerous food such as ice cream, confection, meat products.
Micro encapsulation, the most i.e. refers to utilize some film-formable materials, by core substance (solid particle,
Liquid, solution or suspension) be embedded in one small and close capsule in a kind of technology.It is widely used at present
In food, light industry, medicine, petrochemical industry, agricultural, biotechnology field, many is original due to technology barrier the most not
The product that can develop, is i.e. achieved by microcapsule technology today.
By retrieval, find that the following patent the most relevant to Rhizoma Zingiberis Recens volatile oil microcapsule, document are reported:
A kind of ginger essential oil and/or oleoresin microcapsule and preparation technology (CN1488290A), this microcapsule
Being made up of arabic gum, maltodextrin, soybean protein, ginger essential oil and/or oleoresin, water, this prepares work
Skill, by progressively arabic gum, maltodextrin being added to the water and heating for dissolving, cools down, adds soybean protein
Stirring, temperature adds ginger essential oil and/or oleoresin after being down to room temperature and makees heartwood, by material homogenizing three times,
The mixed liquor cooling that homogenizing is crossed, is spray-dried, is processed into microcapsule granule.
The ginger essential oil microcapsule that the method prepares is mixed and made into wall with arabic gum, maltodextrin, soybean protein
Material, wall material only has one layer, and stability is relatively poor.
Summary of the invention
In place of it is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of Double-wall-layer Rhizoma Zingiberis Recens volatile oil is micro-
The preparation method of capsule, this method double-layer embedment protection Rhizoma Zingiberis Recens volatile oil, improve the stability of capsule.
The present invention realizes the technical scheme of purpose:
A kind of preparation method of Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule, step is as follows:
(1) Rhizoma Zingiberis Recens volatile oil is scattered in internal layer wall material, normal temperature high voltage homogenizing, prepares primary suspension；
(2) primary suspension is distributed in outer layer wall material, adds emulsifying agent, normal temperature high voltage homogenizing, obtain
Secondary suspension；
(3) after secondary suspension lyophilization or spray drying, i.e. obtain Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule.
And, described internal layer wall material be gelatin, Cera Flava, monoglyceride, sodium alginate, chitosan,
One or more mixture of cyclodextrin.
And, described Rhizoma Zingiberis Recens volatile oil is 1:2-8 with the mass ratio of internal layer wall material.
And, described outer layer wall material be ocentyl succinic Rhizoma Dioscoreae starch ester, arabic gum, carrageenan,
Carboxymethyl cellulose, soybean protein isolate, one or more mixture of maltodextrin.
And, the preparation method of described ocentyl succinic Rhizoma Dioscoreae starch ester is: (1) washed by fresh Rhizoma Dioscoreae
Section is removed the peel after Jing, hot air drying at 40～60 DEG C, dried yam slice is pulverized, sieves, according to 1:8
Solid-liquid ratio, in the sodium hydroxide solution of pH=8～10 soak 2～3h, by washing with alcohol for several times, will precipitation
Drying obtains Rhizoma Dioscoreae starch；(2), with Rhizoma Dioscoreae starch as raw material, a certain amount of Rhizoma Dioscoreae starch adds octenyl amber
Amber acid, sodium bicarbonate, mix homogeneously, it is dissolved in a certain amount of ethanol, water bath with thermostatic control concussion 3～6h, treats anti-
After Ying, washing with alcohol, the wet ocentyl succinic Rhizoma Dioscoreae starch ester that centrifugal, collection prepares；By wet
Ocentyl succinic Rhizoma Dioscoreae starch ester is made into certain density starch milk, adds dibastic sodium phosphate-citrate buffer solution,
Regulate certain pH, 40～50 DEG C of preheatings 30～40min, add and account for starch on dry basis content 4～the enzyme of 6%, described
Enzyme include that the mass ratio of alpha-amylase and saccharifying enzyme, alpha-amylase and saccharifying enzyme is 1:8, puts to constant temperature
Shaking table reacts, and reaction is the most alkaline with NaOH solution regulation pH after terminating, enzyme denaturing, sucking filtration, and washing is dried,
Pulverize, sieve and i.e. obtain dry ocentyl succinic Rhizoma Dioscoreae starch ester.And, described emulsifying agent be lecithin,
Tween 80, polysorbate60, sorbester p17, monoglyceride, soybean phospholipid, one or more mixed of sucrose ester
Compound.
And, described Rhizoma Zingiberis Recens volatile oil is the Rhizoma Zingiberis Recens volatile oil of supercritical extraction.
And, described homogenizing is 30-100MPa high pressure homogenize.
And, the component of described Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule and weight fraction are than for ocentyl succinic mountain
Medicine starch ester: gelatin: lecithin: Rhizoma Zingiberis Recens volatile oil: distilled water=5-15: 2-10: 3-10: 1-5: 60-90.
Advantages of the present invention and good effect be:
1, the present invention uses double wall material embedding protection Rhizoma Zingiberis Recens volatile oil, can improve Rhizoma Zingiberis Recens volatile oil and effectively become
Dividing stability, bioavailability is high, solves existing method and can not effectively protect Rhizoma Zingiberis Recens volatile oil effective ingredient
Problem.
2, the Rhizoma Zingiberis Recens volatile oil microcapsule that prepared by the inventive method, product embedding rate is high, reaches 81-98%, bag
Burying effective, microcapsule is prepared under normal temperature condition, uses high pressure homogenize, and the microcapsule ultra-micro powder of formation is equal
Even, good fluidity.
3, the ocentyl succinic Rhizoma Dioscoreae starch ester that prepared by the present invention is shaped as elliposoidal, porous, as outer layer
Wall material embedding rate is high, good stability.Ocentyl succinic Rhizoma Dioscoreae starch ester is natural edible product, and toxicity is less
And free from extraneous odour, preparation technology flow process is succinct, distinct, it is easy to industrialization.
4, the micro encapsulation of the present invention is inherently a kind of protection to Rhizoma Zingiberis Recens volatile oil, can play suppression volatile oil
Volatilization loss, protection volatile oil sensitive composition, avoid its composition to react with other food compositions and reach control
Releasing effect processed, changes the state of Rhizoma Zingiberis Recens volatile oil, Rhizoma Zingiberis Recens volatile oil is transformed into fast dissolving solid powder, effectively
Solve storage and the transportation problem of product.
Accompanying drawing explanation
Fig. 1 is the Electronic Speculum figure of ocentyl succinic Rhizoma Dioscoreae starch ester；
Fig. 2 is the Electronic Speculum figure (display tangent plane) of ocentyl succinic Rhizoma Dioscoreae starch ester.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, and following example are illustrative, no
It is determinate, it is impossible to limit protection scope of the present invention with this.
Embodiment 1:
A kind of preparation method of Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule, step is:
The weighing core materials of 1:2-8 the most in mass ratio is the oil of Rhizoma Zingiberis Recens of supercritical extraction, and inner layer wall material is gelatin, room temperature
Homogenizing, supending；
(2), by outer wall material ocentyl succinic Rhizoma Dioscoreae starch ester 5-15 part, it is dissolved in 60-90 part hot water, cold
But to room temperature, adding 3-10 part lecithin is emulsifying agent, regulates PH2-6；
(3) the suspension that step (1) prepares is distributed in step (2) solution, 15000r/min high speed dispersion
2min, at 30-100MPa high pressure homogenize, is repeated 3 times；
(4), by suspension lyophilization, obtain Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule.
The composition of this Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule is: ocentyl succinic Rhizoma Dioscoreae starch ester: gelatin: ovum
Phospholipid: Rhizoma Zingiberis Recens volatile oil: distilled water=10:5:6:2:80.
Described ocentyl succinic Rhizoma Dioscoreae starch preparation method:
(1) peeling section after fresh Rhizoma Dioscoreae is cleaned, hot air drying at 50 DEG C, by dried Rhizoma Dioscoreae
Sheet is pulverized, and crosses 100 mesh sieves, according to the solid-liquid ratio of 1:8, soaks 2h in the sodium hydroxide solution of pH=9,
Utilize 90% washing with alcohol for several times, precipitation drying is obtained Rhizoma Dioscoreae starch.
(2) with Rhizoma Dioscoreae starch as raw material, a certain amount of Rhizoma Dioscoreae starch will add ocentyl succinic, carbonic acid
Hydrogen sodium, mix homogeneously, it is dissolved in a certain amount of 90% ethanol, water bath with thermostatic control concussion 4h, after question response,
Washing with alcohol 3 times, centrifugal collection wet starch；Ocentyl succinic Rhizoma Dioscoreae starch ester is made into certain density shallow lake
Powder breast, adds dibastic sodium phosphate-citrate buffer solution, regulates certain pH, 40 DEG C of preheating 30min, adds 4%
The enzyme (alpha-amylase: saccharifying enzyme=1:8) of (accounting for starch on dry basis content), puts to constant-temperature table reaction, instead
3 should be precipitated with distilled water wash with 3%NaOH solution regulation pH extremely alkalescence, enzyme denaturing, sucking filtration after terminating
Secondary, then by 70% washing with alcohol three times, dry (45 DEG C), pulverize, cross 100 mesh sieves and i.e. obtain octenyl succinic
Acid Rhizoma Dioscoreae starch ester.Ocentyl succinic Rhizoma Dioscoreae starch ester is white to micro-yellow powder, and product meets China
People's republic's standard GB/T 28,303 2012, is shaped as elliposoidal, porous, as shown in Figure 1, Figure 2 institute
Show.
Embodiment 2:
Ocentyl succinic Rhizoma Dioscoreae starch preparation method as different from Example 1
(1) peeling section after fresh Rhizoma Dioscoreae is cleaned, hot air drying at 50 DEG C, by dried Rhizoma Dioscoreae
Sheet is pulverized, and crosses 100 mesh sieves, according to the solid-liquid ratio of 1:8, soaks 2h in the sodium hydroxide solution of pH=9,
Utilize 90% washing with alcohol for several times, precipitation drying is obtained Rhizoma Dioscoreae starch.
(2) a certain amount of Rhizoma Dioscoreae starch distilled water being configured to certain density starch milk, quick agitating makes
Becoming homogenate, the sodium hydroxide with 2% adjusts the pH value of starch milk, and makes whole course of reaction be maintained at this pH
Value, (addition of anhydride is the 3% of starch on dry basis, adds to add octenyl succinic acid anhydride at a certain temperature
Entering front anhydride dehydrated alcohol to be diluted, anhydride is slowly added in starch milk in 2h), react certain time
With the hydrochloric acid of 5%, pH value is adjusted to 6.5 afterwards, sucking filtration, washing (ethanol solution of 70% washs 3 times)；By pungent
Alkenyl succinic acid Rhizoma Dioscoreae starch ester is made into certain density starch milk, adds dibastic sodium phosphate-citrate buffer solution,
Regulate certain pH, 40 DEG C of preheating 30min, add the enzyme (high-temperature starch of 4% (accounting for starch on dry basis content)
Enzyme: saccharifying enzyme=1:8), to put and react to constant-temperature table, reaction regulates pH extremely with 3%NaOH solution after terminating
Alkalescence, enzyme denaturing, sucking filtration, precipitate 3 times with distilled water wash, then by 70% washing with alcohol three times, drying (45 DEG C),
Cross 100 mesh sieves and i.e. obtain ocentyl succinic Rhizoma Dioscoreae starch ester.Ocentyl succinic Rhizoma Dioscoreae starch ester is white extremely
Micro-yellow powder, product meets National Standard of the People's Republic of China GB 28,303 2012.
Embodiment 3:
As different from Example 1, inner layer wall material is monoglyceride, and outer wall material is sodium carboxymethyl cellulose.
Embodiment 4:
As different from Example 1, inner layer wall material is Cera Flava, and outer wall material is arabic gum and maltodextrin.
Embodiment 5:
As different from Example 1, inner layer wall material is gelatin, and outer wall material is ocentyl succinic Rhizoma Dioscoreae starch
Ester and maltodextrin.
Embodiment 6:
As different from Example 1, inner layer wall material is chitosan, and outer wall material is carrageenan and soybean separation protein
In vain.
Claims (10)
1. the preparation method of a Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule, it is characterised in that: step is as follows:
(1) Rhizoma Zingiberis Recens volatile oil is scattered in internal layer wall material, normal temperature high voltage homogenizing, prepares primary suspension；
(2) primary suspension is distributed in outer layer wall material, adds emulsifying agent, normal temperature high voltage homogenizing, obtain secondary suspension；
(3) after secondary suspension lyophilization or spray drying, i.e. obtain Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule.
Preparation method the most according to claim 1, it is characterised in that: described internal layer wall material be gelatin, Cera Flava,
Monoglyceride, sodium alginate, chitosan, one or more mixture of cyclodextrin.
Preparation method the most according to claim 1, it is characterised in that: described Rhizoma Zingiberis Recens volatile oil and internal layer wall material
Mass ratio is 1:2-8.
Preparation method the most according to claim 1, it is characterised in that: described outer layer wall material is ocentyl succinic
Rhizoma Dioscoreae starch ester, arabic gum, carrageenan, carboxymethyl cellulose, soybean protein isolate, maltodextrin one or both with
On mixture.
Preparation method the most according to claim 1, it is characterised in that: the system of described ocentyl succinic Rhizoma Dioscoreae starch ester
Preparation Method is:
(1) after being cleaned by fresh Rhizoma Dioscoreae, peeling section, hot air drying at 40～60 DEG C, pulverize dried yam slice, mistake
Sieve, according to the solid-liquid ratio of 1:8, soaks 2～3h in the sodium hydroxide solution of pH=8～10, by washing with alcohol for several times, will precipitate
Drying obtains Rhizoma Dioscoreae starch；
(2) with Rhizoma Dioscoreae starch as raw material, addition ocentyl succinic, sodium bicarbonate in a certain amount of Rhizoma Dioscoreae starch, mix homogeneously,
Being dissolved in a certain amount of ethanol, water bath with thermostatic control concussion 3～6h, after question response, washing with alcohol, it is wet that centrifugal, collection prepares
Ocentyl succinic Rhizoma Dioscoreae starch ester；Wet ocentyl succinic Rhizoma Dioscoreae starch ester is made into certain density starch milk, adds
Dibastic sodium phosphate-citrate buffer solution, regulates certain pH, 40～50 DEG C of preheatings 30～40min, adds and account for starch on dry basis content 4～6%
Enzyme, described enzyme includes that the mass ratio of alpha-amylase and saccharifying enzyme, alpha-amylase and saccharifying enzyme is 1:8, puts to constant temperature and shakes
Bed reaction, reaction regulates pH extremely alkalescence, enzyme denaturing, sucking filtration, washing by NaOH solution after terminating, dries, pulverizing, sieve
Obtain dry ocentyl succinic Rhizoma Dioscoreae starch ester.
Preparation method the most according to claim 1, it is characterised in that: described emulsifying agent be lecithin, Tween 80,
Polysorbate60, sorbester p17, monoglyceride, soybean phospholipid, one or more mixture of sucrose ester.
Preparation method the most according to claim 1, it is characterised in that: described Rhizoma Zingiberis Recens volatile oil is the Rhizoma Zingiberis Recens of supercritical extraction
Volatile oil.
Preparation method the most according to claim 1, it is characterised in that: described homogenizing is 30-100MPa high pressure homogenize.
The Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule that preparation method the most according to claim 1 prepares.
Double-wall-layer Rhizoma Zingiberis Recens volatile oil microcapsule the most according to claim 9, it is characterised in that: component and weight fraction ratio
For ocentyl succinic Rhizoma Dioscoreae starch ester: gelatin: lecithin: Rhizoma Zingiberis Recens volatile oil: distilled water=
5-15∶2-10∶3-10∶1-5∶60-90。
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Effective date of registration: 20201112 Address after: No.31 Fu No.1, gengjiaying Village North Street, Kaiping Town, Kaiping District, Tangshan City, Hebei Province 063000 Patentee after: Li Hongqing Address before: No.278, Zone C, 1st floor, block B, investment service center, Caofeidian Comprehensive Bonded Zone, Caofeidian pilot Free Trade Zone, Tangshan, Hebei Patentee before: Hummfrog e-commerce Tangshan Co.,Ltd. Effective date of registration: 20201112 Address after: No.278, Zone C, 1st floor, block B, investment service center, Caofeidian Comprehensive Bonded Zone, Caofeidian pilot Free Trade Zone, Tangshan, Hebei Patentee after: Hummfrog e-commerce Tangshan Co.,Ltd. Address before: 300222 Tianjin University of Science and Technology, 1038 South Road, Tianjin, Hexi District, Dagu Patentee before: Tianjin University of Science and Technology |