CN105789020A - Pulse sample introduction apparatus used for mass spectrometer and mass spectrum equipment - Google Patents
Pulse sample introduction apparatus used for mass spectrometer and mass spectrum equipment Download PDFInfo
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- CN105789020A CN105789020A CN201610278831.4A CN201610278831A CN105789020A CN 105789020 A CN105789020 A CN 105789020A CN 201610278831 A CN201610278831 A CN 201610278831A CN 105789020 A CN105789020 A CN 105789020A
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- centrifuge tube
- capillary
- gripper shoe
- tube
- capillary tube
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
Abstract
A pulse sample introduction apparatus used for a mass spectrometer and mass spectrum equipment possessing the apparatus are disclosed. The pulse sample introduction apparatus comprises a hollow capillary, a centrifugal tube, a driving mechanism and a control module. The driving mechanism is controlled by the control module. A driving effect of the driving mechanism makes that the centrifugal pipe and the hollow capillary generate relative motion so that a tip of the hollow capillary is contacted with a sample solution in the centrifuge tube so as to carry out sample introduction or is separated from the sample solution in the centrifuge tube. A driving mode of the driving mechanism is controlled so that the hollow capillary realizes pulse-type sample introduction. The apparatus has a simple structure, is convenient to control, can realize the pulse sample introduction of the mass spectrometer, guarantees a vacuum degree of a miniature mass spectrometer during a sample introduction process and simultaneously can increase sensitivity and signal intensity of the mass spectrometer.
Description
Technical field
The present invention relates to field of analytic instrument, particularly relate to a kind of for mass spectrometric pulse sample injection device and mass spectroscopy device.
Background technology
Mass spectrograph (MassSpectrometer, MS) is that substance ion is ionized into ion by a class, is easily separated and detects its intensity by mass-to-charge ratio to make the instrument of qualitative and quantitative analysis.One complete mass spectrograph is mainly made up of sampling system (including ion source and ion transmission system), mass analyzer, signal detection system and vacuum system.Mass spectrometric ion sampling system includes ion source and ion transport device, and it is responsible for producing gaseous ion from sample and detecting sample transfer to mass analyzer.The quality of ion sampling system performance is related to the quality of the leading indicators such as mass spectrometric sensitivity, resolution.
In small spectrometer, due to volumetric constraint, generally only set one-level vacuum chamber, when fluid sample is with big flow continuous sample introduction, it will destroy the vacuum in vacuum chamber, thus being substantially reduced the sensitivity of small spectrometer.
Vacuum in small spectrometer during in order to ensure sample introduction, an existing solution is to adopt the capillary tube that internal diameter is little to carry out sample introduction, reduces the unit interval and enters the sample in vacuum chamber and mass analyzer.But this method is unfavorable for obtaining stronger mass signal.
Vacuum in small spectrometer during in order to ensure sample introduction, the solution that another one is widely adopted is to adopt the input mode of DAPI (discontinuous atmospheric pressure lower interface), and the gaseous ion that ionization produces is entered in vacuum chamber and mass analyzer by the valve pulsed in the middle of DAPI.
Summary of the invention
Present invention is primarily targeted at and overcome the deficiencies in the prior art, there is provided one for mass spectrometric pulse sample injection device, its simple in construction, easy to control reliably, it is capable of mass spectrometric Pulsed Sampling, ensure the middle-size and small-size mass spectrometric vacuum of sample introduction process, mass spectrometric sensitivity and signal intensity can be improved simultaneously.Another object is to provide a kind of mass spectroscopy device with this pulse sample injection device.
For achieving the above object, the present invention is by the following technical solutions:
A kind of for mass spectrometric pulse sample injection device, including capillary hollow, centrifuge tube, driving mechanism and control module, described driving mechanism is controlled by described control module, the driving effect of described driving mechanism makes generation relative motion between described centrifuge tube and described capillary hollow, so that the sample solution in the most advanced and sophisticated and described centrifuge tube of described capillary hollow contacts and sample introduction or depart from the sample solution in described centrifuge tube, the type of drive of wherein said driving mechanism is controlled such that described capillary hollow realizes pulsed sample introduction.
Further:
Also including capillary tube and support fixed mechanism, described driving mechanism is drive described centrifuge tube to carry out the centrifuge tube driving mechanism moved, and described capillary hollow is fixed on described capillary tube and supports on fixed mechanism.
Described centrifuge tube driving mechanism includes motor, screw mandrel, feed screw nut and centrifuge tube gripper shoe, described motor is coupled to described screw mandrel, described feed screw nut is arranged on described screw mandrel, described centrifuge tube gripper shoe is fixed on described feed screw nut, described centrifuge tube is arranged in described centrifuge tube gripper shoe, the rotation of described motor is converted into the rectilinear motion of described centrifuge tube gripper shoe by described screw mandrel and described feed screw nut, and described centrifuge tube gripper shoe carries, between described centrifuge tube and described capillary hollow, described relative motion occurs.
Described screw mandrel is erected to arrange, described centrifuge tube gripper shoe is horizontally fixed on described feed screw nut, the rotation of described motor is converted into the rectilinear motion up and down of described centrifuge tube gripper shoe by described screw mandrel and described feed screw nut, described capillary hollow supports fixed mechanism by described capillary tube and is erected to be arranged in the top of described centrifuge tube, and described centrifuge tube gripper shoe drives described centrifuge tube to move up and down to realize the described relative motion between itself and described capillary hollow.
Described capillary tube supports fixed mechanism and includes being erected to the slide bar of layout, being fixed on the connection supports plate of the upper end of described slide bar and be arranged on the capillary tube union joint on described connection supports plate, described capillary hollow is fixed on described capillary tube union joint, described centrifuge tube gripper shoe offers slide bar through hole, described slide bar is through described slide bar through hole, so that described centrifuge tube gripper shoe can slide up and down along described slide bar.
The described slide bar through hole of described centrifuge tube gripper shoe is provided with linear bearing, with described centrifuge tube gripper shoe interference fit outside described linear bearing, the ball inside described linear bearing and described slide bar Structure deformation.
Described capillary tube union joint is logical structure in being, described capillary tube union joint is connected by external screw thread and the screwed hole offered on described connection supports plate are fixing, described capillary hollow is from the middle traverse of described capillary tube union joint and is fixed by the constraint of described capillary tube union joint, preferably, described capillary tube union joint includes annulus that one end hands twists and the gradually little pyramidal structure of the other end, and described pyramidal structure is provided with for revolving friction tight external screw thread with described gripper shoe.
It is provided with capillary tube sleeve pipe between described capillary hollow and described capillary tube union joint, described capillary tube sleeve pipe is deformable material, or described capillary tube sleeve pipe and described capillary tube union joint are variable material, so that described capillary hollow can carry out upper-lower position adjustment for described capillary tube union joint, preferably, described capillary tube sleeve pipe is elastomeric material, and described capillary tube union joint is PEEK or polytetrafluoroethylmaterial material, and described capillary hollow is quartz capillary.
Described control module includes DC source, signal generator and motor driver, described DC source connects motor driver by described signal generator, the control signal that signal generator is produced by described motor driver is modulated, generate and drive signal, and signal will be driven to export to described motor.
A kind of mass spectroscopy device, including mass spectrograph be connected to described mass spectrometric ionogenic sampling device, described sampling device is described pulse sample injection device.
Beneficial effects of the present invention:
Pulse sample injection device according to the present invention, capillary hollow is fixed on capillary tube and supports on fixed mechanism, centrifuge tube driving mechanism is controlled by controlling module, drive and relative motion occurs between centrifuge tube and capillary hollow, so that the tip of capillary hollow contacts with the sample solution in centrifuge tube and sample introduction or depart from the sample solution in centrifuge tube, capillary hollow is made to realize pulsed sample introduction, pulse sample injection device simple in construction according to above-mentioned design, easy to control reliably, it is capable of Pulsed Sampling, ensure the middle-size and small-size mass spectrometric vacuum of sample introduction process, and mass spectrometric sensitivity and signal intensity can be improved.This pulse sample injection device can with uviol lamp ionization source, the plasma source coupling of electron spray ionisation source.Pass through Pulsed Sampling, every subpulse enters into the sample in capillary tube and is not full of capillary tube all the time, but formation fluid column, tube wall is less to the resistance of fluid column, the required fluid column quality driven enters in vacuum chamber also with fluid column and is gradually reduced, this makes sample feeding speed accelerate, and is conducive to improving mass spectrometric sensitivity and signal intensity.
The present invention is capable of capillary tube and contacts with the pulsed on fluid sample surface and pulse period and dutycycle can arbitrarily regulate, it is only necessary to program parameter preset can reach the sample size in automatic-control pulse sample introduction cycle and each cycle.By pulse sample injection device, fluid sample is not continuous sample introduction, it is possible to Large Diameter Pipeline capillary tube is applied on small spectrometer, and meets the requirement of vacuum.Simultaneously, Pulsed Sampling makes fluid sample form a section little fluid column in capillary tube, tube wall is less to the resistance of little fluid column, the required fluid column quality driven enters in vacuum chamber also with fluid column and is gradually reduced, this makes sample feeding speed accelerate, this characteristic is possible not only to utilize on small-sized mass spectrum, is applied to large commercial mass spectrum, is also beneficial to improve sensitivity and the signal intensity of detection.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the pulse sample injection device whole system of the specific embodiment of the invention.
Fig. 2 is the front view of the pulse sample injection device outside the removing control module of the specific embodiment of the invention.
Fig. 3 is the axonometric drawing of the pulse sample injection device outside the removing control module of the specific embodiment of the invention.
Fig. 4 is the structural representation of a preferred embodiment of mass spectroscopy device of the present invention.
Description of reference numerals is as follows:
1 base
2 motor cover
3 motors
4 motor lead screw
5 feed screw nuts
6 linear bearings
7 slide bars
8 connection supports plates
9 capillary tube union joints
10 capillary hollows
11 centrifuge tube gripper shoes
12 centrifuge tubes
13 mass spectrographs
14 ion sources
Detailed description of the invention
Hereinafter embodiments of the present invention are elaborated.It is emphasized that the description below is merely exemplary, rather than in order to limit the scope of the present invention and application thereof.
nullConsult Fig. 1 to Fig. 4，In one embodiment，A kind of for mass spectrometric pulse sample injection device，Including capillary hollow 10、Capillary tube supports fixed mechanism、Centrifuge tube 12、Centrifuge tube driving mechanism and control module，Capillary hollow 10 one end is for being connected in the vacuum chamber of mass spectrograph 13，The other end is as sample feeding end，For contacting with the sample solution in centrifuge tube 12，Described capillary hollow 10 is fixed on described capillary tube and supports on fixed mechanism，Described centrifuge tube driving mechanism is controlled by described control module，Drive generation relative motion between described centrifuge tube 12 and described capillary hollow 10，So that the sample solution in the most advanced and sophisticated and described centrifuge tube 12 of described capillary hollow 10 contacts and sample introduction or depart from the sample solution in described centrifuge tube 12，The type of drive of wherein said centrifuge tube driving mechanism is controlled such that described capillary hollow 10 realizes pulsed sample introduction.
It addition, driving mechanism can also be drive capillary hollow 10 to carry out the driving mechanism that moves relative to centrifuge tube 12, it is also possible to be simultaneously drive capillary hollow 10 and centrifuge tube 12 carries out the driving mechanism of relative motion.
In a preferred embodiment, described centrifuge tube driving mechanism includes motor 3, screw mandrel 4, feed screw nut 5 and centrifuge tube gripper shoe 11, described motor 3 is coupled to described screw mandrel 4, described feed screw nut 5 is arranged on described screw mandrel 4, described centrifuge tube gripper shoe 11 is fixed on described feed screw nut 5, described centrifuge tube 12 is arranged in described centrifuge tube gripper shoe 11, the rotation of described motor is converted into the rectilinear motion of described centrifuge tube gripper shoe 11 by described screw mandrel 4 and described feed screw nut 5, described centrifuge tube gripper shoe 11 carries, between described centrifuge tube 12 and described capillary hollow 10, described relative motion occurs.
In a more preferred embodiment, described screw mandrel 4 is erected to arrange, described centrifuge tube gripper shoe 11 is horizontally fixed on described feed screw nut 5, the rotation of described motor is converted into the rectilinear motion up and down of described centrifuge tube gripper shoe 11 by described screw mandrel 4 and described feed screw nut 5, described capillary hollow 10 supports fixed mechanism by described capillary tube and is erected to be arranged in the top of described centrifuge tube 12, and described centrifuge tube gripper shoe 11 drives described centrifuge tube 12 to move up and down the described relative motion realizing between itself and described capillary hollow 10.
In a more preferred embodiment, described capillary tube supports fixed mechanism and includes being erected to the slide bar 7 of layout, being fixed on the connection supports plate 8 of the upper end of described slide bar 7 and be arranged on the capillary tube union joint 9 on described connection supports plate 8, described capillary hollow 10 is fixed on described capillary tube union joint 9, described centrifuge tube gripper shoe 11 offers slide bar 7 through hole, described slide bar 7 is through described slide bar 7 through hole, so that described centrifuge tube gripper shoe 11 can slide up and down along described slide bar 7.Connection supports plate 8 can be fixed by the top of nut Yu slide bar 7.
In a more preferred embodiment, described slide bar 7 through hole of described centrifuge tube gripper shoe 11 is provided with linear bearing 6, with described centrifuge tube gripper shoe 11 interference fit outside described linear bearing 6, the ball inside described linear bearing 6 and described slide bar 7 Structure deformation.
In a more preferred embodiment, described capillary tube union joint 9 is logical structure in being, described capillary tube union joint 9 is connected by external screw thread and the screwed hole offered on described connection supports plate 8 are fixing, and described capillary hollow 10 is from the middle traverse of described capillary tube union joint 9 and is retrained by described capillary tube union joint 9 and fixes.Preferably, described capillary tube union joint 9 includes annulus that one end hands twists and the gradually little pyramidal structure of the other end, and described pyramidal structure is provided with for revolving friction tight external screw thread with described gripper shoe.
In a more preferred embodiment, it is provided with capillary tube sleeve pipe between described capillary hollow 10 and described capillary tube union joint 9, described capillary tube sleeve pipe is deformable material, or described capillary tube sleeve pipe and described capillary tube union joint 9 are variable material, so that described capillary hollow 10 can carry out upper-lower position adjustment for described capillary tube union joint 9.Preferably, described capillary tube sleeve pipe is elastomeric material, and described capillary tube union joint 9 is PEEK or polytetrafluoroethylmaterial material, and described capillary hollow 10 is quartz capillary.
Capillary hollow 10 at capillary tube union joint 9 and capillary tube sleeve pipe under the constraints, is perpendicularly inserted in the sample solution in centrifuge tube 12.Under capillary hollow 10 pressure at two ends difference or other driving forces, sample solution is fed in mass spectrograph.
In certain embodiments, pulse sample injection device also includes base 1 and motor cover 2, described motor cover 2 can be fixed by screws on described base 1, the groove structure agreed with mutually with described motor 3 it is provided with in described motor cover 2, by described groove structure, described motor 3 is fixed in described motor cover 2, the lower end of described capillary tube support fixed mechanism is fixing with described base 1 to be connected, described base 1, described motor cover 2, described motor, described capillary tube support fixed mechanism and are fixed as one, form certain counterweight, the effect of stable sampling device can be played.
In certain embodiments, described control module includes DC source, signal generator (or claiming signal source) and motor driver, described DC source connects motor driver by described signal generator, the control signal that signal generator is produced by described motor driver is modulated, generate and drive signal, and signal will be driven to export to described motor 3.The up and down motion speed of centrifuge tube, moving up and down time, the highs and lows time of staying all can according to procedural freedom adjustment.
Consulting Fig. 4, in another kind of embodiment, a kind of mass spectroscopy device, including the sampling device of mass spectrograph 13 with the ion source 14 being connected in the vacuum chamber of described mass spectrograph 13, described sampling device can be the pulse sample injection device of aforementioned any embodiment.
Specific embodiments of the invention, its principle and advantage is further described below in conjunction with accompanying drawing.
Fig. 1 show structure and the principle schematic of one specific embodiment of the present invention, and pulse sample injection device includes the frame for movement of signal source, motor driver and pulse sample injection device.
As it is shown in figure 1, in a preferred embodiment of the invention, signal source is an one-chip computer module, and signal source can also is that the programs such as the labview by PC end provide.Signal source produces four road signals, and exports OPTO, DIR, FREE, CP end to motor driver respectively, and wherein OPTO is public oedoeagus, and DIR is motor drive direction level input, and FREE is off line end, and CP is pulse ends.Four tunnel inputs are modulated by motor driver, export the four road signals, four inputs to two-phase four line motor, thus controlling the start and stop of motor, motion rotating speed and turning to.
As shown in Figure 2 to Figure 3, motor lead screw 4 and feed screw nut 5 coordinate, feed screw nut 5 and centrifuge tube gripper shoe 11 are fastenedly connected, centrifuge tube gripper shoe 11 and linear bearing 6 interference fit, centrifuge tube 12 is placed on centrifuge tube gripper shoe 11, inside linear bearing 6, ball contacts with slide bar smooth surface, the start and stop of motor, rotating speed, is diverted through feed screw nut and is converted into turning to of the start and stop of centrifuge tube, shuttle speed and up and down motion.
As shown in Figure 2 to Figure 3, in a preferred embodiment of the invention, the time of sample feeding controls in the following manner: capillary hollow 10 only arrives peak place at centrifuge tube 12 and contacts with sample solution, and centrifuge tube 12 is sample injection time in peak place residence time.In addition, capillary hollow is all disengaged position with the solution in centrifuge tube.The sample injection time in sample introduction cycle and the cycle can be arbitrarily controlled by pre-set programs.
As shown in Figure 2 to Figure 3, described capillary hollow 10 is through capillary tube connector 9, and capillary tube connector 9 plays effect of contraction for capillary hollow 10 so that it is can be perpendicularly inserted in centrifuge tube 12.Preferably, capillary tube connector one end is pyramidal structure, and is provided with screw thread and screws with the screw thread on connection supports plate 8 and coordinate, and the other end is that hands twists annulus, and annulus is provided with reticulate pattern or straight burr, conveniently tightens.Capillary tube union joint 9 has the ability of certain plastic deformation, it is preferable that, it is possible to use the material such as PEEK or politef.
As shown in Figure 2 to Figure 3, nut is by screwing with slide bar 7 threaded upper ends, and by connection supports plate 8 and slide bar 7 compression fit, capillary tube union joint 9 remains static all the time, and relative motion occurs with it for centrifuge tube 12.The position of centrifuge tube 12 can carry out manually adjusting of vertical direction in capillary tube union joint.
As shown in Figure 2 to Figure 3, base 1 and motor cover 2 are fixed by screw, and in motor cover, processing has a groove structure agreed with mutually with electric machine structure, and motor 3 is fixed in motor cover by groove structure.Slide bar 7 lower end thread segment is connected by fixing with base 1 with the cooperation of the screwed hole on base 1, and base, motor cover, motor, slide bar are fixed as one, and form certain counterweight, serve the effect of stable sampling device.
Preferably, described capillary hollow 10 is quartz capillary.The external diameter of capillary hollow 10 can be 50～2000 μm, and internal diameter can be 1～100 μm.
Fig. 4 illustrates the mass spectroscopy device of a kind of embodiment, the uviol lamp ionization source coupling that wherein pulse sample injection device of the present invention is built-in with small spectrometer, it should be noted that, it is not limited to uviol lamp ionization source, it is also possible to be the ionization sources such as electron spray ionisation source (ESI) with the mass spectrometer ion source of pulse sample injection device coupling of the present invention.
Above content is to combine concrete/preferred embodiment further description made for the present invention, it is impossible to assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention; without departing from the inventive concept of the premise; these embodiments having described that can also be made some replacements or modification by it, and these substitute or variant all should be considered as belonging to protection scope of the present invention.
Claims (10)
1. one kind is used for mass spectrometric pulse sample injection device, it is characterized in that, including capillary hollow, centrifuge tube, driving mechanism and control module, described driving mechanism is controlled by described control module, the driving effect of described driving mechanism makes generation relative motion between described centrifuge tube and described capillary hollow, so that the sample solution in the most advanced and sophisticated and described centrifuge tube of described capillary hollow contacts and sample introduction or depart from the sample solution in described centrifuge tube, the type of drive of wherein said driving mechanism is controlled such that described capillary hollow realizes pulsed sample introduction.
2. pulse sample injection device as claimed in claim 1, it is characterized in that, also including capillary tube and support fixed mechanism, described driving mechanism is drive described centrifuge tube to carry out the centrifuge tube driving mechanism moved, and described capillary hollow is fixed on described capillary tube and supports on fixed mechanism.
3. pulse sample injection device as claimed in claim 2, it is characterized in that, described centrifuge tube driving mechanism includes motor, screw mandrel, feed screw nut and centrifuge tube gripper shoe, described motor is coupled to described screw mandrel, described feed screw nut is arranged on described screw mandrel, described centrifuge tube gripper shoe is fixed on described feed screw nut, described centrifuge tube is arranged in described centrifuge tube gripper shoe, the rotation of described motor is converted into the rectilinear motion of described centrifuge tube gripper shoe by described screw mandrel and described feed screw nut, described centrifuge tube gripper shoe carries, between described centrifuge tube and described capillary hollow, described relative motion occurs.
4. pulse sample injection device as claimed in claim 3, it is characterized in that, described screw mandrel is erected to arrange, described centrifuge tube gripper shoe is horizontally fixed on described feed screw nut, the rotation of described motor is converted into the rectilinear motion up and down of described centrifuge tube gripper shoe by described screw mandrel and described feed screw nut, described capillary hollow supports fixed mechanism by described capillary tube and is erected to be arranged in the top of described centrifuge tube, and described centrifuge tube gripper shoe drives described centrifuge tube to move up and down to realize the described relative motion between itself and described capillary hollow.
5. pulse sample injection device as claimed in claim 4, it is characterized in that, described capillary tube supports fixed mechanism and includes being erected to the slide bar of layout, being fixed on the connection supports plate of the upper end of described slide bar and be arranged on the capillary tube union joint on described connection supports plate, described capillary hollow is fixed on described capillary tube union joint, described centrifuge tube gripper shoe offers slide bar through hole, described slide bar is through described slide bar through hole, so that described centrifuge tube gripper shoe can slide up and down along described slide bar.
6. pulse sample injection device as claimed in claim 5, it is characterized in that, the described slide bar through hole of described centrifuge tube gripper shoe is provided with linear bearing, with described centrifuge tube gripper shoe interference fit outside described linear bearing, the ball inside described linear bearing and described slide bar Structure deformation.
7. pulse sample injection device as claimed in claim 5, it is characterized in that, described capillary tube union joint is logical structure in being, described capillary tube union joint is connected by external screw thread and the screwed hole offered on described connection supports plate are fixing, described capillary hollow is from the middle traverse of described capillary tube union joint and is fixed by the constraint of described capillary tube union joint, preferably, described capillary tube union joint includes annulus that one end hands twists and the gradually little pyramidal structure of the other end, and described pyramidal structure is provided with for revolving friction tight external screw thread with described gripper shoe.
8. pulse sample injection device as claimed in claim 7, it is characterized in that, it is provided with capillary tube sleeve pipe between described capillary hollow and described capillary tube union joint, described capillary tube sleeve pipe is deformable material, or described capillary tube sleeve pipe and described capillary tube union joint are variable material, so that described capillary hollow can carry out upper-lower position adjustment for described capillary tube union joint, preferably, described capillary tube sleeve pipe is elastomeric material, described capillary tube union joint is PEEK or polytetrafluoroethylmaterial material, and described capillary hollow is quartz capillary.
9. the pulse sample injection device as described in any one of claim 1 to 8, it is characterized in that, described control module includes DC source, signal generator and motor driver, described DC source connects motor driver by described signal generator, the control signal that signal generator is produced by described motor driver is modulated, generate and drive signal, and signal will be driven to export to described motor.
10. a mass spectroscopy device, including mass spectrograph and be connected to described mass spectrometric ionogenic sampling device, it is characterised in that described sampling device is the pulse sample injection device described in any one of claim 1 to 9.
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| CN201610278831.4A CN105789020B (en) | 2016-04-28 | 2016-04-28 | For mass spectrometric pulse sample injection device and mass spectroscopy device |
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| CN201610278831.4A CN105789020B (en) | 2016-04-28 | 2016-04-28 | For mass spectrometric pulse sample injection device and mass spectroscopy device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111243936A (en) * | 2020-01-17 | 2020-06-05 | 清华大学深圳国际研究生院 | Pulse electrospray ion source, pulse sampling method and mass spectrum detection system |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2029635A (en) * | 1978-08-30 | 1980-03-19 | Leybold Heraeus Gmbh & Co Kg | Mass spectroscopy of fluids leaving a chromatograph |
| CN102478466A (en) * | 2010-11-30 | 2012-05-30 | 中国科学院大连化学物理研究所 | Sampling and sample introduction apparatus for aerosol |
| CN203672851U (en) * | 2014-01-26 | 2014-06-25 | 中国科学院地球环境研究所 | Multi receiving ion coupled plasma mass spectroscopy sampling system |
| CN104661758A (en) * | 2012-10-11 | 2015-05-27 | 塞莫费雪科学（不来梅）有限公司 | Apparatus and method for improving throughput in spectrometry |
| CN204424208U (en) * | 2015-03-31 | 2015-06-24 | 合肥美亚光电技术股份有限公司 | A kind of sample introduction ionizing system for mass spectrometer |
| CN104849412A (en) * | 2015-05-29 | 2015-08-19 | 中国石油大学(北京) | In-situ observation testing device for simulating micro oil displacing interface |
| CN105097411A (en) * | 2014-05-21 | 2015-11-25 | 北京理工大学 | Atmospheric pressure interface device and mass spectrometer |
-
2016
- 2016-04-28 CN CN201610278831.4A patent/CN105789020B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2029635A (en) * | 1978-08-30 | 1980-03-19 | Leybold Heraeus Gmbh & Co Kg | Mass spectroscopy of fluids leaving a chromatograph |
| CN102478466A (en) * | 2010-11-30 | 2012-05-30 | 中国科学院大连化学物理研究所 | Sampling and sample introduction apparatus for aerosol |
| CN104661758A (en) * | 2012-10-11 | 2015-05-27 | 塞莫费雪科学（不来梅）有限公司 | Apparatus and method for improving throughput in spectrometry |
| CN203672851U (en) * | 2014-01-26 | 2014-06-25 | 中国科学院地球环境研究所 | Multi receiving ion coupled plasma mass spectroscopy sampling system |
| CN105097411A (en) * | 2014-05-21 | 2015-11-25 | 北京理工大学 | Atmospheric pressure interface device and mass spectrometer |
| CN204424208U (en) * | 2015-03-31 | 2015-06-24 | 合肥美亚光电技术股份有限公司 | A kind of sample introduction ionizing system for mass spectrometer |
| CN104849412A (en) * | 2015-05-29 | 2015-08-19 | 中国石油大学(北京) | In-situ observation testing device for simulating micro oil displacing interface |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111243936A (en) * | 2020-01-17 | 2020-06-05 | 清华大学深圳国际研究生院 | Pulse electrospray ion source, pulse sampling method and mass spectrum detection system |
| WO2021143078A1 (en) * | 2020-01-17 | 2021-07-22 | 清华大学深圳国际研究生院 | Pulse electrospray ion source, pulse sample injection method, and mass spectrum detection system |
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| CN105789020B (en) | 2017-07-28 |
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