CN105779267A - Optical system used for gene sequencer - Google Patents

Optical system used for gene sequencer Download PDF

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Publication number
CN105779267A
CN105779267A CN201410782413.XA CN201410782413A CN105779267A CN 105779267 A CN105779267 A CN 105779267A CN 201410782413 A CN201410782413 A CN 201410782413A CN 105779267 A CN105779267 A CN 105779267A
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CN
China
Prior art keywords
camera
optical system
adjustment part
eyeglass
installing plate
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Granted
Application number
CN201410782413.XA
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Chinese (zh)
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CN105779267B (en
Inventor
杨斌
刘健
温欣
张永卫
倪鸣
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MGI Tech Co Ltd
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BGI Shenzhen Co Ltd
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Priority to CN201410782413.XA priority Critical patent/CN105779267B/en
Publication of CN105779267A publication Critical patent/CN105779267A/en
Priority to HK16112050.4A priority patent/HK1223966A1/en
Application granted granted Critical
Publication of CN105779267B publication Critical patent/CN105779267B/en
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Abstract

The invention discloses an optical system used for a gene sequencer. The optical system comprises a bearing platform, and a dichronic mirror, a first camera, a reflector assembly and a second camera which are positioned on the bearing platform, the reflector assembly comprises a reflector and an eyeglass adjusting structure, the first camera is arranged in the reflected light path of the dichronic mirror, the reflector assembly is arranged in the transmitted light path of the dichronic mirror, the second camera is arranged in the reflected light path of the reflector, the eyeglass adjusting structure comprises a support, an installing plate and an adjusting portion, the installing plate and the adjusting portion are positioned on the support, the reflector is fixedly arranged on the installing plate, the adjusting portion comprises a first adjusting piece, a second adjusting piece and a third adjusting piece, and the first adjusting piece, the second adjusting piece and the third adjusting piece are triangularly distributed and are connected to the installing plate. The optical system adopting the three adjusting pieces as three adjusting points to adjust the reflected light path of the reflector has the advantages of realization of high-precision camera imaging position alignment, improvement of the debugging convenience, and shortening of the debugging time of the system.

Description

Optical system for gene sequencer
Technical field
The present invention relates in gene sequencing field, more specifically, relate to a kind of optical system for gene sequencer.
Background technology
Current gene sequencer is used mostly optical system and detects system as its core, laser is conventional fluorescence excitation light source, a kind of mode reducing cost is that every kind of laser makes chip to be detected excite the fluorescence of two kinds of wavelength simultaneously, two kinds of fluorescence can be separated by dichroic mirror 102 after same micro-imaging camera lens 100, a kind of fluorescence can be reflected to and reach a camera 104 and carry out imaging and take pictures, another kind of fluorescence can penetrate dichroic mirror 102 and then enter another camera 108 then through reflecting mirror 106 and carry out imaging and take pictures, as shown in Figure 1.
In two photos photographed at the same time, the thing side on chip is same position, but is entered camera by different light paths after dichroic mirror, and the position of the fluorescence photo of two different wave lengths is overlapping theoretically.But actually owing to having the difference of the position of different light paths and camera after dichroic mirror, actually the position of imaging has difference.
Demand based on gene sequencing algorithm, in order to reduce the loss of quantity of information, two camera position deviations are more few more good in XY both direction, to require two pixels, each pixel is the square of the length of side 6.5 microns, and namely two picture location deviations should not exceed 13 microns in XY both direction.The debugging of 13 microns, without special design, alignment need to spend the substantial amounts of time, and effect is not as.
Current optical system, reflecting mirror is on the mirror holder of 45 degree, it is desirable to rely on machining accuracy and the rough alignment adjusting two camera imaging positions of guarantee, but actual effect differs bigger and bad debugging.
Summary of the invention
It is contemplated that at least solve one of technical problem of existence in prior art.For this, the present invention needs to provide a kind of optical system for gene sequencer.
nullA kind of optical system for gene sequencer,Including plummer、It is positioned at the dichroic mirror on this plummer、First camera、Mirror assembly and second camera,This mirror assembly includes reflecting mirror and eyeglass adjusts structure,This first camera is arranged on the reflected light path of this dichroic mirror,This mirror assembly is arranged on the transmitted light path of this dichroic mirror,This second camera is arranged on the reflected light path of this reflecting mirror,This eyeglass adjusts structure and includes support、Installing plate and adjustment portion,This support is fixed on this plummer,This installing plate and this adjustment portion are positioned on this support,This reflecting mirror is fixed on this installing plate,This adjustment portion includes the first adjustment part、Second adjustment part and the 3rd adjustment part,This first adjustment part、This second adjustment part and the distribution of the 3rd adjustment part triangular shape are connected on this installing plate and are provided commonly for the reflection light adjusting this reflecting mirror image space in this second camera.
In above-mentioned optical system, adjust the some reflected light path to adjust illuminator by three adjustment parts as three, it is achieved that high-precision camera imaging position alignment, and improve the convenience of debugging and shorten the debugging time of system.
In one embodiment, this eyeglass adjusts structure and also includes locating piece, and this locating piece is fixed on this plummer and for positioning this support.
In one embodiment, this support includes substrate and the loading plate being connected with this substrate, and this eyeglass adjusts structure and also includes elastomeric pad, and this elastomeric pad is between this installing plate and this loading plate.
In one embodiment, this substrate is provided with support guidance part, and this support guidance part offers the strip-shaped bracket guide hole extended in a first direction, and this first direction is the direction being perpendicular to this first camera optical axis.
In one embodiment, this optical system also includes imaging lens, and this dichroic mirror is arranged on the emitting light path of this imaging lens.
In one embodiment, this plummer offer the first groove and and second groove at this first groove interval, this first camera includes the first pedestal, and this second camera includes the second pedestal, this first pedestal is fixed in this first groove, and this second pedestal is fixed in this two groove.
In one embodiment, this first pedestal is provided with the first guidance part, this first guidance part offers strip the first guide hole extended in a first direction, this second pedestal is provided with the second guidance part, this second guidance part offers strip the second guide hole extended along this first direction, and this first direction is the direction being parallel to first camera optical axis.
In one embodiment, this optical system also includes photosurface adjustment part, and this photosurface adjustment part is arranged on the reflected light path of this reflecting mirror and for adjusting the position of the reflection light of photosurface this reflecting mirror relatively of this second camera.
A kind of optical system for gene sequencer, including plummer, it is positioned at the camera on this plummer and Lens assembly, this Lens assembly includes eyeglass and eyeglass adjusts structure, this camera is arranged on the reflected light path of this eyeglass, this eyeglass adjusts structure and includes support, installing plate and adjustment portion, this support is fixed on this plummer, this installing plate and this adjustment portion are positioned on this support, this eyeglass is fixed on this installing plate, this adjustment portion includes the first adjustment part, second adjustment part and the 3rd adjustment part, this first adjustment part, this second adjustment part and the distribution of the 3rd adjustment part triangular shape are connected on this installing plate and are provided commonly for the reflection light adjusting this eyeglass image space at this camera.
In one embodiment, this optical system also includes photosurface adjustment part, and this photosurface adjustment part is arranged on the reflected light path of this eyeglass and for adjusting the position of the reflection light of photosurface this eyeglass relatively of this camera.
The additional aspect of the present invention and advantage will part provide in the following description, and part will become apparent from the description below, or is recognized by the practice of the present invention.
Accompanying drawing explanation
Above-mentioned and/or the additional aspect of the present invention and advantage are from conjunction with will be apparent from easy to understand the accompanying drawings below description to embodiment, wherein:
Fig. 1 is the light path schematic diagram of the optical system for gene sequencer;
Fig. 2 is the schematic perspective view of the optical system for gene sequencer of better embodiment of the present invention;
Fig. 3 is the enlarged diagram of the optical system III part of Fig. 2;
Fig. 4 is another schematic perspective view of the optical system for gene sequencer of better embodiment of the present invention;
Fig. 5 is the enlarged diagram of the optical system V part of Fig. 4;
Fig. 6 is the schematic perspective view of the eyeglass adjustment structure of the optical system for gene sequencer of better embodiment of the present invention;
Fig. 7 is the part isometric schematic diagram of the eyeglass adjustment structure of the optical system for gene sequencer of better embodiment of the present invention;
Fig. 8 is the floor map of the optical system for gene sequencer of better embodiment of the present invention;And
Fig. 9 is another light path schematic diagram of the optical system for gene sequencer.
Detailed description of the invention
Being described below in detail embodiments of the present invention, the example of described embodiment is shown in the drawings, and wherein same or similar label represents same or similar element or has the element of same or like function from start to finish.The embodiment described below with reference to accompanying drawing is illustrative of, and is only used for explaining the present invention, and is not considered as limiting the invention.
In describing the invention, it is to be understood that term " first ", " second " only for descriptive purposes, and it is not intended that instruction or hint relative importance or the implicit quantity indicating indicated technical characteristic.Thus, define " first ", the feature of " second " can express or implicitly include one or more described features.In describing the invention, " multiple " are meant that two or more, unless otherwise expressly limited specifically.
In describing the invention, it is necessary to explanation, unless otherwise clearly defined and limited, term " installation ", " being connected ", " connection " should be interpreted broadly, for instance, it is possible to it is fixing connection, it is also possible to be removably connect, or connect integratedly;Can be mechanically connected, it is also possible to be electrically connect or can intercom mutually;Can be joined directly together, it is also possible to be indirectly connected to by intermediary, it is possible to be connection or the interaction relationship of two elements of two element internals.For the ordinary skill in the art, it is possible to understand above-mentioned term concrete meaning in the present invention as the case may be.
Following disclosure provides many different embodiments or example for realizing the different structure of the present invention.In order to simplify disclosure of the invention, hereinafter to the parts of specific examples and be set for describe.Certainly, they are only merely illustrative, and are not intended to the restriction present invention.Additionally, the present invention can in different examples repeat reference numerals and/or reference letter, this repetition is for purposes of simplicity and clarity, the relation between itself not indicating discussed various embodiment and/or setting.Additionally, the example of the various specific technique that the invention provides and material, but those of ordinary skill in the art are it can be appreciated that the use of the application of other techniques and/or other materials.
Referring to Fig. 2~Fig. 8, the optical system 20 for gene sequencer of better embodiment of the present invention includes plummer 202, imaging lens 204, dichroic mirror 206, first camera 208, mirror assembly 210 and second camera 212.This imaging lens 204, dichroic mirror 206, first camera 208 and second camera 212 are positioned on plummer 202.
This optical system 20 is that the fluorescence information to sample chip used in gene sequencing detects.Specifically, this sample chip is a tabular chip, and its surface offers the multiple apertures for placing such as DNA molecular.The fluorescence information of sample chip is being carried out in detection process, sample chip is placed on a chip platform being fixed together with plummer 202, each aperture is placed with a DNA molecular, then in these apertures, add corresponding solution, after adding solution, DNA molecular can send corresponding fluorescence, and optical system 20 is by gathering these fluorescence information imaging, and then realizes the detection of the fluorescence information to sample chip.
Plummer 202 is rectangle tabular, and its four angles adopt fillet design, it is to avoid human body is damaged by wedge angle.Plummer 202 offers the first groove 214 and and second groove 216 at this first groove 214 interval.First groove 214 is used for placing first camera 208, and the second groove 216 is used for placing second camera 212.This plummer 202 is further opened with through hole (not shown).
This imaging lens 204 is arranged on plummer 202.Imaging lens 204 wears the fluorescence information that the sample chip on this through hole acquisition chip platform sends.Specifically, imaging lens 204 is microcobjective, is carrying out in detection process to the fluorescence information of sample chip, and the fluorescence that DNA molecular is sent by imaging lens 204 is sent in dichroic mirror 206, first camera 208 and second camera 212.
Dichroic mirror 206 is arranged on the emitting light path of this imaging lens 204.Owing to fluorescence packets is containing multiple color light, dichroic mirror 206 for reflexing to first camera 208 and the other color of light in fluorescence being transmitted through mirror assembly 210 by the one of which color of light in fluorescence.Dichroic mirror 206 includes shell 218, dichroic mirror pedestal 220 and dichroic mirror locating piece 222.Shell 218 is fixed on dichroic mirror pedestal 220, and dichroic mirror eyeglass (not shown) is positioned at shell 218.Dichroic mirror pedestal 220 is provided with dichroic mirror guidance part 224, and this dichroic mirror guidance part 224 offers X in the first direction and extends and be the dichroic mirror guide hole 226 of strip, and the position that plummer 202 is corresponding with dichroic mirror guide hole 226 offers screw.Before fixing dichroic mirror 206, dichroic mirror 206 can be moved in the first direction and adjust the reflection light imaging in first camera 208 of dichroic mirror 206, then pass through screw wear dichroic mirror guide hole 226 and screw tight with screw and the position of fixing dichroic mirror 206, finally utilize screw to tighten dichroic mirror locating piece 222, and then the position of dichroic mirror 206 is fixed on plummer 202.This first direction X is the direction being perpendicular to this first camera 208 optical axis.
First camera 208 is fixed on plummer 202 and offers the position of the first groove 214, and specifically, first camera 208 includes this first pedestal 228 of the first pedestal 228 and is fixed in this first groove 214.By arranging groove 214 so that first camera 208 is easier to mate with the reflection light of spectroscope 206 on horizontal level.This first pedestal 228 is provided with the first guidance part 230, and this first guidance part 230 offers strip the first guide hole 232 that Y extends in a second direction.This second direction Y is perpendicular to first direction X.
This mirror assembly 210 is arranged on the transmitted light path of this dichroic mirror 206.This mirror assembly 210 includes reflecting mirror 234 and eyeglass adjusts structure 236.This eyeglass adjusts structure 236 and includes support 238, installing plate 240, adjustment portion 242 and locating piece 244.This installing plate 240 and this adjustment portion 242 are positioned on this support 238, this reflecting mirror 234 is fixed on this installing plate 240, this adjustment portion 242 includes the first adjustment part the 246, second adjustment part 248 and the 3rd adjustment part 249, and this first adjustment part 246, this second adjustment part 248 and the distribution of the 3rd adjustment part 249 triangular shape are connected on this installing plate 240 and are provided commonly for the reflection light adjusting this reflecting mirror 234 image space in this second camera 212.
This support 238 is substantially L-shaped, and it includes substrate 250 and the loading plate 252 being connected with this substrate 250.This loading plate 252 offers three screws 254.This substrate 250 is provided with support guidance part 256, and support guidance part 256 offers the strip-shaped bracket guide hole 258 that X extends in the first direction.Substrate 250 is further opened with the accepting hole 260 being positioned on this support guide hole 258 and communicating with support guide hole 258, when behind the position using screw fixed support 238, the nut of screw can be contained in accepting hole 260, nut and substrate 250 surface are substantially flush, it is to avoid human body is damaged by the nut of protrusion.
In present embodiment, first adjustment part the 246, second adjustment part 248 and the 3rd adjustment part 249 are screw, and it wears three screws 254 of loading plate 252 respectively and is connected with installing plate 240.Therefore, three adjustment parts adjust point triangular shape distribution as three so that one plane of 3 definition, by rotating the adjustment part of correspondence, more obtain installing plate 240 and reflecting mirror 234 position also changes, and then the reflection light that have adjusted reflecting mirror 234 enters the position of second camera 212.
Further, ginseng Fig. 8, this eyeglass adjusts structure 236 and also includes elastomeric pad 262, this elastomeric pad 262 is between this installing plate 240 and this loading plate 252, therefore, the vibrations passing to reflecting mirror 234 in adjustment process are reduced as far as, and are conducive to the reflection light alignment at second camera 212 image space of reflecting mirror 234.The material of elastomeric pad 262 is selected from gum elastic or other elastomeric material.
This locating piece 244 is fixed on this plummer 202 and for positioning this support 238.Locating piece 244 offers positioning through hole 264 and is fixed by screws on plummer 202.Specifically, locating piece 244 is T-shaped, and it includes two lateral mass 266, and each lateral mass 266 offers positioning through hole 264, plummer 202 offers the screw communicated with this positioning through hole 264, and screw wears positioning through hole 264 and is spirally connected with corresponding screw and is fixed on plummer 202 by locating piece 244.
Second camera 212 is fixed on plummer 202 and offers the position of the second groove 216, and specifically, second camera 212 includes this second pedestal 268 of the second pedestal 268 and is fixed in this second groove 216.By arranging groove 216 so that second camera 212 is easier to mate with the reflection light of reflecting mirror 234 on horizontal level.
This second pedestal 268 is provided with the second guidance part 270, and this second guidance part 270 offers strip the second guide hole 272 that Y extends in a second direction.Second camera 212 receives the reflection light of reflecting mirror 234 and to these photoimagings, and then realizes the detection of the fluorescence information to sample chip.
This optical system 20 also includes photosurface adjustment part 274, and this photosurface adjustment part 274 is arranged on the reflected light path of this reflecting mirror 234 and for adjusting the position of the photosurface reflected light path of this reflecting mirror 234 relatively of this second camera 212.
Specifically, second camera 212 also includes adjustment block 276, this adjustment block 276 is positioned on this second pedestal 268 and fixes with photosurface and is connected, and this photosurface adjustment part 274 includes adjusting screw 278 and elastic component (not shown), and this elastic component is positioned between this adjustment block 276 and second pedestal 268.
When adjusting the screw 278 direction to close plummer 202 and screwing in, adjusting screw 278 can will drive adjustment block 276 and the photosensitive direction towards close plummer 202 to move, adjustment block 276 compression elastic piece simultaneously.When adjusting screw 278 and screwing out to the direction away from plummer 202, elastic component promotes adjustment block 276 and the photosensitive direction away from plummer 202 to move because of the effect of restoring force.Therefore, the relative position of the photosurface of screw 278 also adjustable second camera 212 and the reflection light of reflecting mirror 234 is adjusted.
Optical system 20 is when adjusting, first imaging lens 204 and dichroic mirror 206 are adjusted, the imaging of the reflection light of dichroic mirror 206 is mixed up by first camera 208, then with first camera 208 for reference, adjusts second camera 212 and make both align the image space of the transmission light of dichroic mirror 206.Specifically, dichroic mirror 206 can pass through to translate in the first direction on plummer 202, makes the reflection light of dichroic mirror 206 and then in first camera 208, afterwards, utilizes screw lock dichroic mirror 206 by dichroic mirror pedestal 220 and tighten dichroic mirror locating piece 222.
Afterwards, translatable mirror assembly 210 in the first direction, the reflection light making reflecting mirror 234 is roughly the same with the image space of first camera 208 at the image space of second camera 212, utilizes screw lock support 238 by support guidance part 256, and tightens locating piece 244.
Then, finely tune by adjusting first adjustment part the 246, second adjustment part 248 and/or the 3rd adjustment part 249 reflection light image space in second camera 212 to reflecting mirror 234, certainly, above-mentioned adjustment can be combined with photosurface adjustment part 274 and adjusts together so that adjust more flexible.
In above-mentioned optical system 20, adjust the some reflected light path to adjust illuminator 234 by three adjustment parts 246,248,249 as three, it is achieved that high-precision camera imaging position alignment, and improve the convenience of debugging and shorten the debugging time of system.
Further, in the fluorescence photo that each camera of optical system 20 of gene sequencer photographed, the image space of each camera is more accurate to obtaining the more accurate fluorescence photo analysis to the later stage, so the accurate alignment of the image space of each camera, it is possible to improve the accuracy of order-checking very well, reduce the loss of quantity of information.
The image space of each camera of optical system 20 of gene sequencer alignment request is high, so in the debugging process of optical system 20, the debugging in this stage need to spend the result that bigger manpower and time carries out debugging and being not readily available.After adopting above-mentioned eyeglass to adjust structure 236, it is possible to more convenient debugging more efficiently to desired effect, make producers can the debugging of completion system in shorter time, shorten the debugging time of system, improve the production efficiency of system.
It is to be noted, the optical system of the present invention is not limited to the image space alignment of two cameras, when optical system demand or when increasing more imaging band, as shown in Figure 9, this optical system increases dichroic mirror and the image camera of correspondence respectively, dichroic mirror or reflecting mirror before the camera increased use above eyeglass adjustment structure 236 to install equally, and then fine setting makes the image space of each camera be directed at reference position one by one, thus reaching the effect that all camera imaging positions are accurately directed at.It is understood that reference camera is also not necessarily first camera near imaging lens, it is possible to be some of last or centre, then finely tune the reflecting mirror before other camera or dichroic mirror angle is directed at.
In the description of this specification, specific features, structure, material or feature that the description of reference term " embodiment ", " some embodiments ", " exemplary embodiment ", " example ", " concrete example " or " some examples " etc. means in conjunction with described embodiment or example describe are contained at least one embodiment or the example of the present invention.In this manual, the schematic representation of above-mentioned term is not necessarily referring to identical embodiment or example.And, the specific features of description, structure, material or feature can combine in an appropriate manner in any one or more embodiments or example.
While embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that: these embodiments can being carried out multiple change, amendment, replacement and modification when without departing from principles of the invention and objective, the scope of the present invention is limited by claim and equivalent thereof.

Claims (10)

  1. null1. the optical system for gene sequencer,It is characterized in that,Including plummer、It is positioned at the dichroic mirror on this plummer、First camera、Mirror assembly and second camera,This mirror assembly includes reflecting mirror and eyeglass adjusts structure,This first camera is arranged on the reflected light path of this dichroic mirror,This mirror assembly is arranged on the transmitted light path of this dichroic mirror,This second camera is arranged on the reflected light path of this reflecting mirror,This eyeglass adjusts structure and includes support、Installing plate and adjustment portion,This support is fixed on this plummer,This installing plate and this adjustment portion are positioned on this support,This reflecting mirror is fixed on this installing plate,This adjustment portion includes the first adjustment part、Second adjustment part and the 3rd adjustment part,This first adjustment part、This second adjustment part and the distribution of the 3rd adjustment part triangular shape are connected on this installing plate and are provided commonly for the reflection light adjusting this reflecting mirror image space in this second camera.
  2. 2. optical system as claimed in claim 1, it is characterised in that this eyeglass adjusts structure and also includes locating piece, and this locating piece is fixed on this plummer and for positioning this support.
  3. 3. optical system as claimed in claim 1, it is characterised in that this support includes substrate and the loading plate being connected with this substrate, this eyeglass adjusts structure and also includes elastomeric pad, and this elastomeric pad is between this installing plate and this loading plate.
  4. 4. optical system as claimed in claim 3, it is characterised in that this substrate is provided with support guidance part, and this support guidance part offers the strip-shaped bracket guide hole extended in a first direction, and this first direction is the direction being perpendicular to this first camera optical axis.
  5. 5. optical system as claimed in claim 1, it is characterised in that this optical system also includes imaging lens, and this dichroic mirror is arranged on the emitting light path of this imaging lens.
  6. 6. optical system as claimed in claim 1, it is characterized in that, this plummer offer the first groove and and second groove at this first groove interval, this first camera includes the first pedestal, this second camera includes the second pedestal, this first pedestal is fixed in this first groove, and this second pedestal is fixed in this two groove.
  7. 7. optical system as claimed in claim 6, it is characterized in that, this first pedestal is provided with the first guidance part, this first guidance part offers strip the first guide hole extended in a first direction, this second pedestal is provided with the second guidance part, this second guidance part offers strip the second guide hole extended along this first direction, and this first direction is the direction being parallel to first camera optical axis.
  8. 8. optical system as claimed in claim 1, it is characterized in that, this optical system also includes photosurface adjustment part, and this photosurface adjustment part is arranged on the reflected light path of this reflecting mirror and for adjusting the position of the reflection light of photosurface this reflecting mirror relatively of this second camera.
  9. 9. the optical system for gene sequencer, it is characterized in that, including plummer, it is positioned at the camera on this plummer and Lens assembly, this Lens assembly includes eyeglass and eyeglass adjusts structure, this camera is arranged on the reflected light path of this eyeglass, this eyeglass adjusts structure and includes support, installing plate and adjustment portion, this support is fixed on this plummer, this installing plate and this adjustment portion are positioned on this support, this eyeglass is fixed on this installing plate, this adjustment portion includes the first adjustment part, second adjustment part and the 3rd adjustment part, this first adjustment part, this second adjustment part and the distribution of the 3rd adjustment part triangular shape are connected on this installing plate and are provided commonly for the reflection light adjusting this eyeglass image space at this camera.
  10. 10. optical system as claimed in claim 9, it is characterised in that this optical system also includes photosurface adjustment part, this photosurface adjustment part is arranged on the reflected light path of this eyeglass and for adjusting the position of the reflection light of photosurface this eyeglass relatively of this camera.
CN201410782413.XA 2014-12-16 2014-12-16 Optical system for gene sequencer Active CN105779267B (en)

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Application Number Priority Date Filing Date Title
CN201410782413.XA CN105779267B (en) 2014-12-16 2014-12-16 Optical system for gene sequencer
HK16112050.4A HK1223966A1 (en) 2014-12-16 2016-10-19 Optical system for use in a gene sequencer

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Application Number Priority Date Filing Date Title
CN201410782413.XA CN105779267B (en) 2014-12-16 2014-12-16 Optical system for gene sequencer

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CN105779267A true CN105779267A (en) 2016-07-20
CN105779267B CN105779267B (en) 2018-01-12

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Publication number Priority date Publication date Assignee Title
CN112326553A (en) * 2018-10-30 2021-02-05 深圳市真迈生物科技有限公司 Method of regulation
CN113106012A (en) * 2021-04-08 2021-07-13 埃妥生物科技(杭州)有限公司 Gene detector
CN113125388A (en) * 2019-12-30 2021-07-16 长春长光华大智造测序设备有限公司 Fluorescence imaging device and gene sequencer

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CN1198444C (en) * 2003-05-12 2005-04-20 致伸科技股份有限公司 Fixture applied between photoelectronic module and photomechanical casing
CN1661415A (en) * 2004-02-25 2005-08-31 东友科技股份有限公司 Scanning module capable of fine adjusting optical path
CN201133953Y (en) * 2007-11-23 2008-10-15 深圳市大族激光科技股份有限公司 Light splitting adjustment spectacle-frame device
CN103186017A (en) * 2011-12-29 2013-07-03 中强光电股份有限公司 Adjusting device of projector and adjusting device of lens
CN203443767U (en) * 2013-08-28 2014-02-19 中国计量科学研究院 Auxiliary positioner for detecting integration refractometer, and optical detection system

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Publication number Priority date Publication date Assignee Title
CN1198444C (en) * 2003-05-12 2005-04-20 致伸科技股份有限公司 Fixture applied between photoelectronic module and photomechanical casing
CN1661415A (en) * 2004-02-25 2005-08-31 东友科技股份有限公司 Scanning module capable of fine adjusting optical path
CN201133953Y (en) * 2007-11-23 2008-10-15 深圳市大族激光科技股份有限公司 Light splitting adjustment spectacle-frame device
CN103186017A (en) * 2011-12-29 2013-07-03 中强光电股份有限公司 Adjusting device of projector and adjusting device of lens
CN203443767U (en) * 2013-08-28 2014-02-19 中国计量科学研究院 Auxiliary positioner for detecting integration refractometer, and optical detection system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112326553A (en) * 2018-10-30 2021-02-05 深圳市真迈生物科技有限公司 Method of regulation
CN112326553B (en) * 2018-10-30 2022-11-11 深圳市真迈生物科技有限公司 Method of regulation
CN113125388A (en) * 2019-12-30 2021-07-16 长春长光华大智造测序设备有限公司 Fluorescence imaging device and gene sequencer
CN113106012A (en) * 2021-04-08 2021-07-13 埃妥生物科技(杭州)有限公司 Gene detector

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CN105779267B (en) 2018-01-12

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