CN105770985A - Composite hydrocolloid, hydrocolloid dressing and preparation method of composite hydrocolloid - Google Patents
Composite hydrocolloid, hydrocolloid dressing and preparation method of composite hydrocolloid Download PDFInfo
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- CN105770985A CN105770985A CN201610140213.3A CN201610140213A CN105770985A CN 105770985 A CN105770985 A CN 105770985A CN 201610140213 A CN201610140213 A CN 201610140213A CN 105770985 A CN105770985 A CN 105770985A
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- compound water
- water colloid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
- A61L2300/622—Microcapsules
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
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Abstract
The invention relates to composite hydrocolloid, a preparation method thereof and a hydrocolloid dressing. The composite hydrocolloid is prepared from the following raw materials: 15 to 90 parts of an effective component, 10 to 30 parts of sodium carboxymethylcellulose and 40 to 100 parts of an adhesive, wherein the effective component comprises tourmaline powder and/or tea tree essential oil wrapped by microcapsules. The far infrared tea tree essential oil application is suitable for later recovery of superficial wounds and burn and scald wounds and inflammation elimination and nursing of acnes, and has a more outstanding effect than common inflammation elimination medicines or dressings.
Description
Technical field
The present invention relates to a kind of Compound Water colloid, bearing hydrocolloid dressing and preparation method thereof.
Background technology
Hydrocolloid functional dressing is a kind of to have the novel of advantage such as adsorptivity, waterproof, anti, moisturizing and apply ointment or plaster.Current hydrocolloid functional dressings application is extensive, and the material adopted and the auxiliary material of interpolation determine different special efficacies and the wound surface type nursed, and bearing hydrocolloid dressing quality is very different on the market, distinguishes very big.For different wound surface features, it is necessary to safety is good and has the hydrocolloid functional dressing of specific function.
From domestic and international patent retrieval to the patent of multinomial hydrocolloid, this type of hydrocolloid patent of applying ointment or plaster mainly adopts the adjuvants such as styrene, gelatin, chitosan, calcium alginate fibre, silver ion, and functional relatively single, effect cannot be lasting, and safety needs demonstration.
Summary of the invention
The technical problem to be solved is for the deficiencies in the prior art, it is provided that Compound Water colloid, its preparation method and the bearing hydrocolloid dressing that a kind of effect is good and lasting.
For solving above-mentioned technical problem, the present invention adopts the following technical scheme that:
A kind of Compound Water colloid, by weight, its composition of raw materials includes:
Effective ingredient 15~90 parts;
Sodium carboxymethyl cellulose 10~30 parts;
Adhesive 40~100 parts,
Wherein, described effective ingredient is the tea tree ethereal oil of tourmaline powder and/or encapsulation.
Preferably, described effective ingredient is the tea tree ethereal oil of the encapsulation of the tourmaline powder of 5~50 weight portions and 10~40 weight portions.
It is further preferred that the particle diameter of described tourmaline powder is 200 order~300 orders.
It is further preferred that tea tree ethereal oil is 1:1~2 with the mass ratio of microcapsule in the tea tree ethereal oil of described encapsulation.
Preferably, the preparation method of the tea tree ethereal oil of described encapsulation is: tea tree ethereal oil and microcapsule are mixed at 5~30 DEG C.
Specifically, described microcapsule is the microcapsule of the slow breaking cellular wall of meeting more than 30 DEG C.
The commercially available acquisition of microcapsule in the present invention, for instance the microcapsule being main component with pectin, maltodextrin and water can be adopted.
Tea tree ethereal oil is adopted encapsulation, overcome that tea tree ethereal oil water solublity is poor, volatile, unstable chemcial property, readily volatilized, the shortcoming such as fragrance and fragrance of scattering and disappearing during using and storing, under ensureing the premise that derived essential oil does not lose, green is harmless, there is again slow release, antioxidation, easily storage, easily interpolation and composite feature simultaneously.
Tea tree ethereal oil in the present invention is the tea tree ethereal oil extracted through steam distillation by Camellia sinensis plant, it is of course also possible to adopt city available from tea tree ethereal oil.
Preferably, described adhesive is polyisobutylene medical hot melt adhesive.
The all commercially available acquisition of other raw materials in the present invention.
The preparation method that the present invention also provides for a kind of described Compound Water colloid, described adhesive is added heat fusing at 130~150 DEG C, it is subsequently adding described sodium carboxymethyl cellulose and described effective ingredient, stirs at 100~130 DEG C, make described Compound Water colloid.
Preferably, in the adhesive after adding heat fusing, add described tourmaline powder and described sodium carboxymethyl cellulose, stir at 120~130 DEG C, then add the tea tree ethereal oil of encapsulation, at 100~120 DEG C, vacuum constant temperature stirring 5~15min, makes described Compound Water colloid.
Preferably, at 120~130 DEG C, 60~90min is stirred.
The present invention also provides for a kind of bearing hydrocolloid dressing suitable in ulceration and non-ulceration inflammation affected part, including fixed layer, peel ply and the Compound Water colloid layer between described fixed layer and described peel ply, described Compound Water colloid layer is formed by described Compound Water colloid.
Preferably, the material of described fixed layer and described peel ply is independently selected from release paper, polyurethane film, grid non-woven fabrics.
The preparation method that the invention still further relates to a kind of described bearing hydrocolloid dressing, described Compound Water colloid injection mo(u)lding is formed described Compound Water colloid layer on described fixed layer, covering described peel ply on described Compound Water colloid layer, then compression molding obtains described bearing hydrocolloid dressing.
Due to the utilization of technique scheme, the present invention compared with prior art has the advantage that
The bearing hydrocolloid dressing that the present invention prepares is applicable to postoperative, burn and scald and the nursing of other shallow wound surface, is particularly suitable for small pox acne skin, more efficient elimination wound inflammation, and timeliness and is more than 12 hours;The bearing hydrocolloid dressing of the present invention, be adopt natural plants Camellia sinensis quintessence oil be that raw material combines with hydrocolloid, utilize thermoelectricity and piezoelectric effect that constant speed Controlled release technology and tourmaline powder discharge, improve local blood circulation, promote the metabolism of muscle cell, excite that tea tree ethereal oil active component is more effective acts on wound surface, absorb wound exudate simultaneously, reach the multi-efficiency that antiphlogistic antibacterial, quickly-healing and prevention of scar are formed.
The bearing hydrocolloid dressing stable in properties that the present invention prepares, nontoxic, strong adaptability, soft comfortable, good springiness, adhesion wound, environmental protection, safe and sanitary, effect is obvious and period of storage is long.
Detailed description of the invention
The product of the present invention has the advantage that (1), antiinflammatory are invigorated blood circulation; alleviate pain: tea tree ethereal oil is combined with hydrocolloid and far infrared composition; rapid osmotic hair follicle is nursed one's health; effectively eliminate skin or wound inflammation; gel is formed after hydrocolloid and Wound contact; the teleneuron that protection exposes, alleviates pain.(2), tea tree ethereal oil: tea tree ethereal oil is the extract of Camellia sinensis.There is bactericidal antiphlogistic, restrain pore, prevent the effects such as infection.For infected wound and burn, good therapeutical effect of having tanned severely.Especially that oiliness, small pox skin nursing effect is splendid, improve wound surface redness, restrain pore, Bergamot Mint Extract, bactericidal antiphlogistic.(3), far infrared composition, activating cell: far infrared composition and contact skin can produce piezoelectric effect and pyroelectric effect, form microcirculation, increase local location metabolism, accelerate tissue to bring back to life, promote that ferment generates, thus reaching the effect of activation histiocyte, strengthening skin immunocompetence.(4), without hormone, skin friendly, safer more relieved: hydrocolloid has the effect of waterproof, anti, moisture-heat preservation, the environment of wound moist can be kept, make granulation and epithelial tissue ordering growth, accelerating wound healing, reduce the formation of cicatrix.Quickly absorb wound sepage, prevent traumatic infection, comfortable persistently, not easily stay cicatrix.This product is without adding hormone and antibiotics raw material, and colloid surface softness is gentle, to skin nonirritant, has better security performance.(5), the elite memory technology of original creation, with grid non-woven fabrics for base material, pin quintessence oil composition and not volatile, persist to wound site: far infrared tea tree ethereal oil hydrocolloid is applied ointment or plaster and mutually merged by certain proportioning by three kinds of materials, form cooperative effect, simultaneously act on wound surface or skin inflammatory body, can be applicable to shallow wound surface, the empyrosis wound surface later stage recovers, the inflammation of small pox acne class eliminates and nursing, and the Probability of effectively counteracting bedsores or pressure ulcer in advance, more more significantly than common anti-inflammatory drugs or dressing effect.
Below in conjunction with specific embodiment, the present invention is described in further details.Should be understood that these embodiments are an illustration for the ultimate principle of the present invention, principal character and advantage, and the present invention not scope by following example is limited.The implementation condition adopted in embodiment can do further adjustment according to specific requirement, and not marked implementation condition is generally the condition in normal experiment, and room temperature is generally about 25 DEG C.
Embodiment 1
A kind of bearing hydrocolloid dressing, its preparation method is as follows:
Step (1), at normal temperatures the microcapsule of the tea tree ethereal oil of 5 weight portions and 5 weight portions is mixed and made into the tea tree ethereal oil of encapsulation;
Step (2), the polyisobutylene medical hot melt adhesive of 40 weight portions is heated in blender to 130 DEG C to fusing, 5 weight portions, particle diameter are the tourmaline powder of 200 orders and the sodium carboxymethyl cellulose of 10 weight portions is slowly added to, vacuum constant temperature stirring 60min at 120 DEG C;
Step (3), being slowly added to the tea tree ethereal oil of encapsulation that step (1) prepares in the reaction system of step (2), at 100 DEG C, vacuum constant temperature stirring 5min, makes Compound Water colloid;
Step (4), Compound Water colloid injection mo(u)lding is formed on grid non-woven fabrics Compound Water colloid layer, Compound Water colloid layer covers release paper, then compression molding, then carry out cross cutting and be packaged to be bearing hydrocolloid dressing product.
Embodiment 2
A kind of bearing hydrocolloid dressing, its preparation method is as follows:
Step (1), at normal temperatures the microcapsule of the tea tree ethereal oil of 20 weight portions and 20 weight portions is mixed and made into the tea tree ethereal oil of encapsulation;
Step (2), the polyisobutylene medical hot melt adhesive of 100 weight portions is heated in blender to 150 DEG C to fusing, 50 weight portions, particle diameter are the tourmaline powder of 300 orders and the sodium carboxymethyl cellulose of 30 weight portions is slowly added to, vacuum constant temperature stirring 90min at 130 DEG C;
Step (3), being slowly added to the tea tree ethereal oil of encapsulation that step (1) prepares in the reaction system of step (2), at 120 DEG C, vacuum constant temperature stirring 15min, makes Compound Water colloid;
Step (4), Compound Water colloid injection mo(u)lding is formed on grid non-woven fabrics Compound Water colloid layer, Compound Water colloid layer covers release paper, then compression molding, then carry out cross cutting and be packaged to be bearing hydrocolloid dressing product.
Embodiment 3
A kind of bearing hydrocolloid dressing, its preparation method is as follows:
Step (1), at normal temperatures the microcapsule of the tea tree ethereal oil of 10 weight portions and 10 weight portions is mixed and made into the tea tree ethereal oil of encapsulation;
Step (2), the polyisobutylene medical hot melt adhesive of 70 weight portions is heated in blender to 140 DEG C to fusing, 30 weight portions, particle diameter are the tourmaline powder of 250 orders and the sodium carboxymethyl cellulose of 20 weight portions is slowly added to, vacuum constant temperature stirring 70min at 125 DEG C;
Step (3), being slowly added to the tea tree ethereal oil of encapsulation that step (1) prepares in the reaction system of step (2), at 110 DEG C, vacuum constant temperature stirring 10min, makes Compound Water colloid;
Step (4), Compound Water colloid injection mo(u)lding is formed on grid non-woven fabrics Compound Water colloid layer, Compound Water colloid layer covers release paper, then compression molding, then carry out cross cutting and be packaged to be bearing hydrocolloid dressing product.
The bearing hydrocolloid dressing that above-described embodiment 1 to 3 is prepared, and respectively 10 examples common scratch patient and 10 example small pox patients are tried out by common bearing hydrocolloid dressing purchased from market, use the average healing of the patient of various bearing hydrocolloid dressing and treatment situation referring to table 1.
Table 1
Above the present invention is described in detail; its object is to allow the personage being familiar with this art will appreciate that present disclosure and to be carried out; can not limit the scope of the invention with this; the equivalence that all spirit according to the present invention are made changes or modifies, and all should be encompassed in protection scope of the present invention.
Claims (10)
1. a Compound Water colloid, it is characterised in that: by weight, its composition of raw materials includes:
Effective ingredient 15 ~ 90 parts;
Sodium carboxymethyl cellulose 10 ~ 30 parts;
Adhesive 40 ~ 100 parts,
Wherein, described effective ingredient is the tea tree ethereal oil of tourmaline powder and/or encapsulation.
2. Compound Water colloid according to claim 1, it is characterised in that: described effective ingredient is the tea tree ethereal oil of the encapsulation of the tourmaline powder of 5 ~ 50 weight portions and 10 ~ 40 weight portions.
3. Compound Water colloid according to claim 2, it is characterised in that: the particle diameter of described tourmaline powder is 200 order ~ 300 orders.
4. Compound Water colloid according to claim 2, it is characterised in that: in the tea tree ethereal oil of described encapsulation, tea tree ethereal oil is 1:1 ~ 2 with the mass ratio of microcapsule.
5. Compound Water colloid according to claim 1, it is characterised in that: the preparation method of the tea tree ethereal oil of described encapsulation is: tea tree ethereal oil and microcapsule are mixed at 5 ~ 30 DEG C.
6. Compound Water colloid according to claim 1, it is characterised in that: the microcapsule that described microcapsule is described is the microcapsule of the slow breaking cellular wall of meeting more than 30 DEG C.
7. Compound Water colloid according to claim 6, it is characterised in that: described adhesive is polyisobutylene medical hot melt adhesive.
8. the preparation method of the Compound Water colloid as according to any one of claim 1 to 7, it is characterized in that: described adhesive is added heat fusing at 130 ~ 150 DEG C, it is subsequently adding described sodium carboxymethyl cellulose and described effective ingredient, stir at 100 ~ 130 DEG C, make described Compound Water colloid.
9. the preparation method of Compound Water colloid according to claim 8, it is characterized in that: in the adhesive after adding heat fusing, add described tourmaline powder and described sodium carboxymethyl cellulose, stir at 120 ~ 130 DEG C, then the tea tree ethereal oil of encapsulation is added, at 100 ~ 120 DEG C, stir 5 ~ 15min, make described Compound Water colloid.
10. the bearing hydrocolloid dressing being applicable to ulceration and non-ulceration inflammation affected part, including fixed layer, peel ply and the Compound Water colloid layer between described fixed layer and described peel ply, it is characterised in that: described Compound Water colloid layer Compound Water colloid according to any one of claim 1 to 7 is formed.
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CN201610140213.3A CN105770985A (en) | 2016-03-11 | 2016-03-11 | Composite hydrocolloid, hydrocolloid dressing and preparation method of composite hydrocolloid |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110101899A (en) * | 2019-04-10 | 2019-08-09 | 湖北中部医疗科技有限公司 | A kind of medical use hydrocolloid dressing and preparation method thereof |
CN110141678A (en) * | 2019-04-19 | 2019-08-20 | 广东泰宝医疗科技股份有限公司 | A kind of alginates physical therapy liquid dressing and preparation method thereof |
CN112716919A (en) * | 2021-01-21 | 2021-04-30 | 巍太医疗科技(常州)有限公司 | Skin protective agent and preparation method thereof |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110101899A (en) * | 2019-04-10 | 2019-08-09 | 湖北中部医疗科技有限公司 | A kind of medical use hydrocolloid dressing and preparation method thereof |
CN110141678A (en) * | 2019-04-19 | 2019-08-20 | 广东泰宝医疗科技股份有限公司 | A kind of alginates physical therapy liquid dressing and preparation method thereof |
CN112716919A (en) * | 2021-01-21 | 2021-04-30 | 巍太医疗科技(常州)有限公司 | Skin protective agent and preparation method thereof |
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