CN105770659A - Traditional Chinese medicine oral preparation for treating asthma and preparing method thereof - Google Patents

Traditional Chinese medicine oral preparation for treating asthma and preparing method thereof Download PDF

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Publication number
CN105770659A
CN105770659A CN201610360442.6A CN201610360442A CN105770659A CN 105770659 A CN105770659 A CN 105770659A CN 201610360442 A CN201610360442 A CN 201610360442A CN 105770659 A CN105770659 A CN 105770659A
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CN
China
Prior art keywords
medicinal liquid
heat
parts
asthma
time
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Pending
Application number
CN201610360442.6A
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Chinese (zh)
Inventor
温红媚
温腾江
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Shangrao Shajiang High-Tech Biology Co Ltd
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Shangrao Shajiang High-Tech Biology Co Ltd
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Priority to CN201610360442.6A priority Critical patent/CN105770659A/en
Publication of CN105770659A publication Critical patent/CN105770659A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention relates to a traditional Chinese medicine oral preparation for treating asthma and a preparing method thereof. The traditional Chinese medicine oral preparation is prepared from folium mori, herba polygalae japonicae, apricot kernel, papaya radix stemonae, dried tangerine or orange peel, herba selaginellae moellendorfii, licorice root and lean pork. Chinese herbal medicine is adopted, medication safety is realized, preparation is easy, and cost is low. Clinical treatment observation proves that diagnosis and treatment effect is ideal, and relapse does not occur easily after cure.

Description

A kind of extract oral agent treating asthma and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, especially a kind of extract oral agent treating asthma and preparation method thereof.
Background technology
Asthma is the commonly encountered diseases of middle-aged and elderly people, frequently-occurring disease, at present, whole world asthmatic patient about 300,000,000 people, Chinese patients with asthma about 30,000,000.Asthma is to affect the able-bodied important diseases of people.Treatment not in time, lack of standardization, asthma be likely to fatal.In use medicine prevents, treats in the process of asthma at present, and existing Chinese medicine preparation is mostly unsatisfactory, so as to asthma incidence rate increases, sequela is more serious, threatens people's life and affects patients ' life quality.
Summary of the invention
Extract oral agent for the treatment of asthma that it is an object of the invention to provide a kind of better efficacy and preparation method thereof.
The Chinese medicine preparation for the treatment of asthma of the present invention, it is made up of the raw material of following weight proportioning:
Folium Mori 2-40 part Herba Polygalae Japonicae 3-50 part
Semen Armeniacae Amarum 10-50 part Fructus Chaenomelis 3-15 part
Radix Stemonae 0.5-30 part Pericarpium Citri Reticulatae 4-13 part
Herba Selaginellae Involventis 2.5-16 part Radix Glycyrrhizae 1.5-5 part
Thin pork 1-6 part.
The preparation method of a kind of extract oral agent treating asthma of the present invention is to carry out according to following steps:
1) take above-mentioned medical material to clean, mix thoroughly by the preparation of above-mentioned medical material consumption proportion, pack with gauze bag and put into extraction pot;
2) in extraction pot, add the drinkable water being higher than bundle pack 10-15 centimetre to soak 10-20 minute, heat 1 hour, obtain first time medicinal liquid, then medicinal liquid is pumped into heat-preserving container and store, then add second time water, after second time heating 40~50 minutes, obtain second time medicinal liquid, squeeze in heat insulation tank with pump again and store, add again third time water again, heat again 40~50 minutes, it is thus achieved that third time medicinal liquid;
3) in extraction pot, take out bundle pack, then the medicinal liquid pump being stored in heat-preserving container is returned Hybrid Heating in extraction pot be concentrated to medicinal liquid molten long-pending 1/3, the medicinal liquid of concentration is got to defecator through pump and carries out essence filtration;
4) thin pork is individually extracted decoction and 3) in concentrated medicament be mixed in proportion stirring, add mountain plough acid potassium food antiseptics and namely make the extract oral agent of asthma, by after different size medicine bottle fill product.
Above-mentioned each medicine composition consumption represents their proportionate relationship, in actual production can expanding or shrinking at double as required, this all represents protection scope of the present invention.
Above-mentioned each taste medicine has the pharmacological action of self, in respective dosage range, can show its intended pharmacological action.
In side the Radix Stemonae have control lung man heat, upper gas, cough, main lung moistening;Folium Mori have clearing away lung-heat and moistening for dryness, cough-relieving, reduce phlegm and internal heat, reduce phlegm, control night sweat;Herba Polygalae Japonicae has antitussive, reduces phlegm, and invigorates blood circulation, hemostasis, calms the nerves, removing toxic substances;Herba Selaginellae Involventis has clearing away heat and promoting diuresis,;Pericarpium Citri Reticulatae has the merit of appetizing in regulating QI and lowering the adverseness, tune, drying dampness to eliminate phlegm;Radix Glycyrrhizae can cover the pharyngeal mucosa of inflammation, relaxes the inflammation stimulation to it, thus playing antitussive effect;Containing amygdaloside in Semen Armeniacae Amarum, amygdaloside can be hydrolyzed by the emulsin that enteric microorganism enzyme or Semen Armeniacae Amarum itself are contained in vivo, produces hydrocyanic acid and the benzaldehyde of trace, respiratory center is had inhibitory action, reaches antitussive, antiasthmatic effect.
All medicines in the middle of full side share, and to relieving asthma, profit larynx, bactericidal antiphlogistic, expectorant activating QI is primary efficacy.
The oral preparation of Chinese traditional medicinal clinical treatment observation result of the present invention is as follows:
One, basic document: have complete documentation asthma cases 160 example, the oldest 86 years old, minimum 8 years old.
Two, Therapeutic Method: each serving 50ml, three times on the one, child is cut down according to the circumstance, and takes 2 day.
Within 6th, it is a course for the treatment of, according to its body situation, takes 3-4 the asthma recovery from illness course for the treatment of.
Three, efficacy result: above-mentioned case is through taking asthma extract oral agent, and cure rate reaches 75%, improves filter and reaches 20%, inefficiency 5%.
Detailed description of the invention
The raw material components of embodiment and weight thereof is:
20 parts of Herba Polygalae Japonicae of Folium Mori 30 parts
30 portions of Fructus Chaenomeliss of Semen Armeniacae Amarum 10 parts
5 parts of Pericarpium Citri Reticulataes of the Radix Stemonae 6 parts
3 parts of 8 portions of Radix Glycyrrhizaes of Herba Selaginellae Involventis
Thin pork 2 parts.
The preparation method of a kind of extract oral agent treating asthma of embodiment is to carry out according to following steps:
1) take above-mentioned medical material to clean, mix thoroughly by the preparation of above-mentioned medical material consumption proportion, pack with gauze bag and put into extraction pot;
2) in extraction pot, add the drinkable water being higher than bundle pack 15 centimeters to soak 20 minutes, heat 1 hour, obtain first time medicinal liquid, then medicinal liquid is pumped into heat-preserving container and store, then add second time water, after second time heating 50 minutes, obtain second time medicinal liquid, squeeze in heat insulation tank with pump again and store, add again third time water again, heating 45 minutes again, it is thus achieved that third time medicinal liquid;
3) in extraction pot, take out bundle pack, then the medicinal liquid pump being stored in heat-preserving container is returned Hybrid Heating in extraction pot be concentrated to medicinal liquid molten long-pending 1/3, the medicinal liquid of concentration is got to defecator through pump and carries out essence filtration;
4) thin pork is individually extracted decoction and 3) in concentrated medicament be mixed in proportion stirring, add mountain plough acid potassium food antiseptics and namely make the extract oral agent of asthma, by after different size medicine bottle fill product.

Claims (2)

1. the extract oral agent treating asthma, it is characterised in that: the medicament that it is mainly made up of the crude drug of following weight portion:
2~40 parts of Herba Polygalae Japonicae of Folium Mori 3~50 parts
10~50 portions of Fructus Chaenomeliss of Semen Armeniacae Amarum 3~15 parts
0.5~30 part of Pericarpium Citri Reticulatae of the Radix Stemonae 4~13% parts
1.5~5 parts of 2.5~16 portions of Radix Glycyrrhizaes of Herba Selaginellae Involventis
Thin pork 1~6 part.
2. the extract oral agent for the treatment of asthma according to claim 1, it is characterised in that it carries out according to following steps:
1) take above-mentioned medical material to clean, mix thoroughly by the preparation of above-mentioned medical material consumption proportion, pack with gauze bag and put into extraction pot;
2) in extraction pot, add the drinkable water being higher than bundle pack 10-15 centimetre to soak 10-20 minute, heat 1 hour, obtain first time medicinal liquid, then medicinal liquid is pumped into heat-preserving container and store, then add second time water, after second time heating 40~50 minutes, obtain second time medicinal liquid, squeeze in heat insulation tank with pump again and store, add again third time water again, heat again 40~50 minutes, it is thus achieved that third time medicinal liquid;
3) in extraction pot, take out bundle pack, then the medicinal liquid pump being stored in heat-preserving container is returned Hybrid Heating in extraction pot be concentrated to medicinal liquid molten long-pending 1/3, the medicinal liquid of concentration is got to defecator through pump and carries out essence filtration;
4) thin pork is individually extracted decoction and 3) in concentrated medicament be mixed in proportion stirring, add mountain plough acid potassium food antiseptics and namely make the extract oral agent of asthma, by after different size medicine bottle fill product.
CN201610360442.6A 2016-05-28 2016-05-28 Traditional Chinese medicine oral preparation for treating asthma and preparing method thereof Pending CN105770659A (en)

Priority Applications (1)

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CN201610360442.6A CN105770659A (en) 2016-05-28 2016-05-28 Traditional Chinese medicine oral preparation for treating asthma and preparing method thereof

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Application Number Priority Date Filing Date Title
CN201610360442.6A CN105770659A (en) 2016-05-28 2016-05-28 Traditional Chinese medicine oral preparation for treating asthma and preparing method thereof

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Publication Number Publication Date
CN105770659A true CN105770659A (en) 2016-07-20

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CN201610360442.6A Pending CN105770659A (en) 2016-05-28 2016-05-28 Traditional Chinese medicine oral preparation for treating asthma and preparing method thereof

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1947754A (en) * 2006-10-23 2007-04-18 北京羚锐伟业科技有限公司 Medicine for treating infantile asthma and its prepn. method
CN104383397A (en) * 2014-12-06 2015-03-04 唐云峰 Traditional Chinese medicine composition for treating cough type asthma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1947754A (en) * 2006-10-23 2007-04-18 北京羚锐伟业科技有限公司 Medicine for treating infantile asthma and its prepn. method
CN104383397A (en) * 2014-12-06 2015-03-04 唐云峰 Traditional Chinese medicine composition for treating cough type asthma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吕传彬: "春暖饮汤有讲究", 《烹调知识》 *
贺振泉: "《一病一食疗》", 30 September 1999, 广东经济出版社 *

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Application publication date: 20160720