CN100536887C - Compound Chinese and western medicine mixture for children stomatitis and preparation method thereof - Google Patents
Compound Chinese and western medicine mixture for children stomatitis and preparation method thereof Download PDFInfo
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- CN100536887C CN100536887C CNB2007100622137A CN200710062213A CN100536887C CN 100536887 C CN100536887 C CN 100536887C CN B2007100622137 A CNB2007100622137 A CN B2007100622137A CN 200710062213 A CN200710062213 A CN 200710062213A CN 100536887 C CN100536887 C CN 100536887C
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Abstract
The invention discloses a compound medicinal mixture for treating children's stomatitis and its preparing process, wherein the constituents comprises the following raw materials: paris rhizome 2-4g, belamcanda rhizome 3-5g, dittany bark 3g-5g, dahurian angelica root 0.5-2g, natural indigo 0.5-2g, figwirt root 0.3-3g, borax 0.5-3g, pellet sand 0.05-1g, borneol 0.02 g-2g, gentamycin 80000-160000 units, lignocaine hydrochloride 0.05-0.1g, and the preparing process comprises proportioning the medical herbs in pieces, rouging, grinding the raw materials into 120-160 mesh powder, airing, charging gentamycin, lidocaine hydrochloride and right amount of 0.9% physiological saline solution, mixing homogeneously.
Description
Technical field
The present invention relates to Chinese medicine and western medicine compound preparation field, specifically disclose a kind of compound infantile stomatitis Chinese and Western medicine mixture with and preparation method thereof.
Background technology
Infantile stomatitis is children's's common disease, and its reveal any symptoms is: oral cavity pain, sialorrhea, tongue and oral mucosa and lip all have hyperemia in various degree, pus bubble, ulcer, rotten face etc., cause the pediatric diet difficulty of sucking the breast, serious be difficult to feed, make the head of a family feel simply helpless, anxiety is worried.Mostly be conventional therapy such as antibiotic medicine, antimicrobial drug etc. and treat this symptom at present, not appearing in the newspapers as yet has specific drug to occur.As everyone knows, children's's nature are afraid of to take medicine, are afraid of to have an injection, are difficult for transfusion, and the medicine of general treatment infantile stomatitis disease, mostly be for oral administration or injection, so children's has suffered from oral inflammation in general family, children's often crys and is reluctant to take medicine or have an injection in the family, treatment is difficult to, and it is slow to take effect, weak curative effect.
Summary of the invention
Purpose of the present invention is with regard to the sprayability topical drug and the related manufacturing processes thereof of the treatment infantile stomatitis disease that is to provide a kind of Nover practical of inventing according to the unique nature of children's, curative effect height of the present invention, short treating period, be external spraying medicament, spraying gets final product, make things convenient for children's to use, existing relatively medicine and treatment advantage are clear and definite.
Technical scheme of the present invention is: the present invention is a compound infantile stomatitis Chinese and Western medicine mixture, its prescription is made up of the raw material of following component: Rhizoma Paridis 2g-4g, Rhizoma Belamcandae 3g-5g, Cortex Dictamni 3g-5g, Radix Angelicae Dahuricae 0.5g-2g, Indigo Naturalis 0.5g-2g, Radix Scrophulariae 3g-5g, Borax 0.5g-3g, cinnabar 0.05g-0.5g, Borneolum Syntheticum 0.2g-0.5g, unit of gentamycin 80,000 units-160,000, lidocaine hydrochloride 0.05g-0.1g.
The preparation method of compound infantile stomatitis Chinese and Western medicine mixture of the present invention: choose pure first-class crude drug decoction pieces according to above-mentioned each Chinese medicine component proportioning, remove clean impurity, earlier Rhizoma Paridis, Rhizoma Belamcandae, Cortex Dictamni, the Radix Angelicae Dahuricae, Radix Scrophulariae, Indigo Naturalis, Borax, Borneolum Syntheticum is ground into the thin powder of 120-160 orders, cinnabar water is flown to be ground to nothing friction sense be degree, dry and be piece, each Chinese medicine ingredients mix homogeneously that cinnabar after will grinding again is good with previous development, in the container of the lucifuge of packing into sealing, by the time the time spent adds gentamycin according to proportioning in the prescription, lidocaine hydrochloride and an amount of 0.9% normal saline mix homogeneously are made the exterior-applied liquid medicine agent medicine that can spray use then.
0.9% the normal saline that adds in above-mentioned preparation process is preferably 15ml-30ml.
Infantile stomatitis is children's's common disease, because of turbid damp pents up in the intestines and stomach, is hard and dry, makes functional activity of QI being not smooth, the disposition agitation, and cloudy gas secretly consumes, and scorching the going up of fire steamed, and aphtha of the mouth and tongue.The present invention is for the Chinese classical Chinese medical theory and use to execute in conjunction with modern Western medicine and control the Chinese and Western compound mixture that medical knowledge is invented.This prescription is separated: Radix Scrophulariae, Rhizoma Paridis, Cortex Dictamni, Indigo Naturalis function are yin nourishing removing heat from blood, clearing away heat-fire detoxifcation; Rhizoma Belamcandae, Borax, Radix Angelicae Dahuricae function are that dampness is removed expectorant; Borneolum Syntheticum, cinnabar, gentamycin and lidocaine hydrochloride function are that pain relieving is more burst, putrefaction-removing granulation-promoting.And each herbal medicine raw material cooperation can reach replenishing YIN and removing heat among the we, removing pathogenic heat from blood and toxic substance from the body, and removing dampness and eliminating phlegm, the pathogenic fire purging pain relieving is more burst, the effect of putrefaction-removing granulation-promoting.The present invention directly removes the cause of disease in a word, and relief of symptoms is the fastest, treating both the principal and secondary aspects of a disease.
The present invention is in use: for external is sprayed at ulcer surface, one is three times to five times, is 0.5ml-1ml at every turn, according to patient's situation is general use three to five days after, the patient can fully recover.
Below sum up to some clinical datas between 8 days April in 2007 on April 8th, 2006 for the present invention:
Treat 85 routine infantile stomatitis patients during this time altogether, age at 6 months to 5 one full year of life, wherein 55 examples adopt external spray liniment of the present invention, use this medicament 3-5 times on the one according to the patient is different, each use amount is at 0.5-1ml, this 55 example can be the treatment group, and other 30 examples are to adopt the matched group that can be of routine medication, and routine administration is antibiotic, QINGKAILING, VC.
Showing as of infantile stomatitis: oral cavity pain, sialorrhea, tongue and oral mucosa and lip surface all have in various degree congested, pus bubble, ulcer, have rotten face, children's to suck the breast, take food and maybe can not take food because of pain is good enough, check that the blood item is higher than normal value.
Therapeutic process and result: the treatment group through spray this preparation one day after in, the patient all can diet or is sucked the breast, congestive symptom did not have in second day, ulcer surface dwindles, children's's spirit was normal in the 3rd day, the 4th day, and symptomatology disappeared and fully recovered in the 5th day, and its effective percentage and cure rate are 100%; And treatment of control group five days, its effective percentage is 100%, but cure rate only is 70%.
Through above-mentioned actual clinical sum up and the inventor for many years result of the test can to draw medicine of the present invention be according to the practicality of the unique nature invention of children's and the external spraying medicine of novel treatment infantile stomatitis.Curative effect height of the present invention, short treating period, easy to use, spraying get final product, has solved children's and has been afraid of to have an injection, is afraid of to take medicine, is difficult for the medication problem of infusing, and it shows as safely, saves time, makes things convenient for respect to conventional therapy, curative effect is high.Being the perfect compound preparation in conjunction with ancient Chinese medicine and modern Western medicine, can removing cause of disease relief of symptoms directly, faster, is the active drug and the Therapeutic Method for the treatment of both the principal and secondary aspects of a disease.
The specific embodiment
Embodiment 1: choose pure first-class crude drug decoction pieces, remove clean impurity, elder generation is Rhizoma Paridis 2g wherein, Rhizoma Belamcandae 4g, and Cortex Dictamni 4g, Radix Angelicae Dahuricae 1g, Indigo Naturalis 1g, Radix Scrophulariae 3g, Borax 1g, Borneolum Syntheticum 0.9g grinds and makes the thin powder of 120 orders-160 order; Again 0.09g cinnabar water being flown to be ground to does not have the friction sense for spending, dry and be piece, each Chinese medicine ingredients mix homogeneously that cinnabar after will grinding again is good with previous development, in the container of the lucifuge of packing into sealing, by the time the time spent adds gentamycin 100,000 units, lidocaine hydrochloride 0.06g and 0.9% the normal saline mix homogeneously that is equipped with 18ml are made the infantile stomatitis external Chinese and Western medicine mixture that can spray use.
Embodiment 2: choose pure first-class crude drug decoction pieces, remove clean impurity, elder generation is Rhizoma Paridis 3g wherein, Rhizoma Belamcandae 3g, and Cortex Dictamni 5g, Radix Angelicae Dahuricae 2g, Indigo Naturalis 1.5g, Radix Scrophulariae 4g, Borax 2g, Borneolum Syntheticum 0.5g grinds and makes the thin powder of 120 orders-160 order; The 0.09g cinnabar being ground to does not have the friction sense for spending again, dry and be piece, each Chinese medicine ingredients mix homogeneously that cinnabar after will grinding again is good with previous development, in the container of the lucifuge of packing into sealing, by the time the time spent adds gentamycin 120,000 units, lidocaine hydrochloride 0.08g and 0.9% the normal saline mix homogeneously that is equipped with 20ml are made the infantile stomatitis external Chinese and Western medicine mixture that can spray use.
Embodiment 3: choose pure first-class crude drug decoction pieces, remove clean impurity, elder generation is Rhizoma Paridis 4g wherein, Rhizoma Belamcandae 5g, and Cortex Dictamni 3g, Radix Angelicae Dahuricae 1.5g, Indigo Naturalis 2g, Radix Scrophulariae 3g, Borax 2g, Borneolum Syntheticum 0.5g grinds and makes the thin powder of 120 orders-160 order; The 0.1g cinnabar being ground to does not have the friction sense for spending again, dry and be piece, each Chinese medicine ingredients mix homogeneously that cinnabar after will grinding again is good with previous development, in the container of the lucifuge of packing into sealing, by the time the time spent adds gentamycin 120,000 units, lidocaine hydrochloride 0.08g and 0.9% the normal saline mix homogeneously that is equipped with 25ml are made the infantile stomatitis external Chinese and Western medicine mixture that can spray use.
Claims (3)
1, compound infantile stomatitis Chinese and Western medicine mixture is characterized in that: this medicine is made up of the raw material of following component,
Rhizoma Paridis 2g one 4g, Rhizoma Belamcandae 3g one 5g, Cortex Dictamni 3g one 5g, Radix Angelicae Dahuricae 0.5g one 2g, Indigo Naturalis 0.5g one 2g, Radix Scrophulariae 3g one 5g, Borax 0.5g one 3g, cinnabar 0.05g one 0.5g, Borneolum Syntheticum 0.2g one 1g, one 16 ten thousand units of gentamycin 80,000 units, lidocaine hydrochloride 0.05g one 0.1g.
2, the preparation method of the described compound infantile stomatitis of claim 1 Chinese and Western medicine mixture, it is characterized in that: choose the crude drug decoction pieces according to above-mentioned each Chinese medicine component proportioning, remove clean impurity, earlier Rhizoma Paridis, Rhizoma Belamcandae, Cortex Dictamni, the Radix Angelicae Dahuricae, Radix Scrophulariae, Indigo Naturalis, Borax, Borneolum Syntheticum is ground into the thin powder of 120 1 160 orders, cinnabar is ground to nothing friction sense is degree, dry for soon, each Chinese medicine ingredients mix homogeneously that cinnabar after will grinding again is good with previous development, in the container of the lucifuge of packing into sealing, by the time the time spent adds gentamycin according to proportioning in the prescription, lidocaine hydrochloride and an amount of 0.9% normal saline mix homogeneously are made the exterior-applied liquid medicine agent medicine that can spray use then.
3, the preparation method of compound infantile stomatitis Chinese and Western medicine mixture according to claim 2 is characterized in that: 0.9% the normal saline that adds in above-mentioned preparation process is 15ml one 30ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100622137A CN100536887C (en) | 2007-06-28 | 2007-06-28 | Compound Chinese and western medicine mixture for children stomatitis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100622137A CN100536887C (en) | 2007-06-28 | 2007-06-28 | Compound Chinese and western medicine mixture for children stomatitis and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
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| CN101085167A CN101085167A (en) | 2007-12-12 |
| CN100536887C true CN100536887C (en) | 2009-09-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2007100622137A Expired - Fee Related CN100536887C (en) | 2007-06-28 | 2007-06-28 | Compound Chinese and western medicine mixture for children stomatitis and preparation method thereof |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110339282A (en) * | 2019-07-31 | 2019-10-18 | 吉林大学 | Chinese medicine composition and preparation method thereof for treating recurrent aphthous ulcer |
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Granted publication date: 20090909 Termination date: 20110628 |