CN105770498A - Traditional Chinese medicine liquor for treating hemiplegia occurring after ischemic cerebral apoplexy and preparation method thereof - Google Patents
Traditional Chinese medicine liquor for treating hemiplegia occurring after ischemic cerebral apoplexy and preparation method thereof Download PDFInfo
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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Abstract
The invention belongs to traditional Chinese medicine liquor for treating hemiplegia occurring after ischemic cerebral apoplexy and a preparation method thereof. The traditional Chinese medicine liquor is prepared from, by weight, 40-240 parts of milkvetch roots, 40-60 parts of caulis spatholobi, 6-12 parts of leeches, 20-60 parts of earthworms, 20-40 parts of zaocys dhumnade, 12-40 parts of rhizoma gastrodiae, 40-60 parts of herba aristolochiae mollissimae and 800-5000 parts of pure grain baijiu. The traditional Chinese medicine liquor prepared from milkvetch roots, caulis spatholobi, leeches, earthworms, zaocys dhumnade, rhizoma gastrodiae, herba aristolochiae mollissimae and the pure grain baijiu has the effects of reinforcing qi, nourishing blood, dispersing blood stasis and dredging the collaterals and is significant in treatment effect on the symptoms such as the hemiplegia, weak, limp and useless affected extremities and numbness and inconvenient flexion and extension which occur due to qi deficiency and blood stasis generated after the ischemic cerebral apoplexy.
Description
Technical field
The invention belongs to medicated wine technical field, be specifically related to a kind of treat Chinese medicinal liquor of hemiplegia and preparation method thereof after ischemia apoplexy.
Background technology
Apoplexy is due to imbalance of YIN and YANG, and QI and blood is inverse disorderly, on violate in caused by brain.Stroke in convalescent stage, deficiency of qi and blood, hyperamization row is unable, blood vessels numbness resistance occur hemiplegia, suffering limb weak and limp need not, numbness, joint stuffiness etc. be primary symptom.And use merely western medicine primary disease, DeGrain, most of patients easily leaves the sequela such as deformity or aphasis, brings great misery to patient.
Summary of the invention
It is an object of the invention to provide Chinese medicinal liquor of hemiplegia and preparation method thereof after a kind for the treatment of ischemia apoplexy that can significantly improve clinical symptoms, safe and reliable, taking convenience.
For achieving the above object, the technical solution used in the present invention is, a kind of treat the Chinese medicinal liquor of hemiplegia after ischemia apoplexy, be made up of the crude drug of following portions by weight: Radix Astragali 40-240 part, Caulis Spatholobi 40-60 part, Hirudo 6-12 part, Pheretima 20-60 part, Zaocys 20-40 part, Rhizoma Gastrodiae 12-40 part, Herba Aristolochiae Mollissimae 40-60 part, 40 ~ 60 ° of brewing grains white spirit 800-5000 parts.
Preferably, after described treatment ischemia apoplexy, the Chinese medicinal liquor of hemiplegia, is made up of the crude drug of following portions by weight: the Radix Astragali 120 parts, Caulis Spatholobi 50 parts, Hirudo 8 parts, Pheretima 40 parts, Zaocys 30 parts, 30 parts of Rhizoma Gastrodiae, 50 parts, 40 ~ 60 ° brewing grains white spirits of Herba Aristolochiae Mollissimae 1200 parts.
The preparation method of the Chinese medicinal liquor of hemiplegia after described treatment ischemia apoplexy: add after the Radix Astragali, Caulis Spatholobi, Hirudo, Pheretima, Zaocys, Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae are all pulverized and mixed in container, add 40 ~ 60 ° of brewing grains white spirits, soak 25 ~ 35 days, isolate medicated liquor, to obtain final product.
Usage and dosage: oral, a 20ml, within 1st, take twice.
The pharmacology of Chinese medicinal liquor of the present invention is as follows:
Brewing grains white spirit: acrid in the mouth, sweet, extremely hot in nature, can cold expelling, promoting the circulation of blood, dredging collateral.Have and easily dissipate, encourage the characteristic of drug effect.With wine as the leaching extracting solvent, beneficially Effective Component of Chinese Medicine.Medicated wine can strengthen again expelling wind and cold, promoting blood circulation to remove obstruction in the collateral, the merit of eliminating stasis to stop pain.
The Radix Astragali: sweet in the mouth, slightly warm in nature, return spleen, lung meridian.Can QI invigorating with hemopoietic, can manage it again stagnant.The hemiplegia not all right to blood stagnancy due to deficiency of QI or numb and weak and limp unable, compatibility Pheretima curative effect is more preferably.It is additionally operable to the diseases such as the phlegm-damp caused by deficiency of vital energy water wet mistake fortune, edema.
Caulis Spatholobi: bitter in the mouth, sweet, warm in nature, return Liver Channel.This product energy nourshing blood and promoting blood circulation relaxing muscles and tendons and activating QI and blood in the collateral, control quadriplegia after apoplexy, and the medicine of compatibility benefiting QI for activating blood circulation dredging collateral is with more excellent by curative effect.
Hirudo: salty in the mouth, hardship, property is put down, is returned Liver Channel.This product can enter blood system, removing blood stasis, and the high effect of its power is grand.Hirudin in fresh Hirudo salivary gland, hirudin can stop the thrombin effect to Fibrinogen, stops blood coagulation.
Pheretima: salty in the mouth, cold in nature, return liver, spleen, bladder warp.Pheretima is longer than current meridians, is used for treating the disease such as blood stagnancy due to deficiency of QI, hemiplegia.
Zaocys: property is flat, sweet in the mouth, returns Liver Channel.This product can search ailment said due to cold or exposure, the meridian dredging, controls brothers and delays, it is impossible to stretches the migratory arthralgia etc. of act.
Rhizoma Gastrodiae: sweet in the mouth, property is put down, is returned Liver Channel.Rhizoma Gastrodiae can be dispelled exogenous wind, and the meridian dredging is used for treating the diseases such as wind apoplex involving the channels and collaterals, hands and feet caused by paralysis, numb limbs and tense tendons.
Herba Aristolochiae Mollissimae: acrid in the mouth, hardship, property is put down, is returned Liver Channel.There is the merit of removing obstruction in the collateral to relieve pain, for diseases such as numb limbs and tense tendons.
The beneficial effect comprise that, the Chinese medicinal liquor that the Radix Astragali, Caulis Spatholobi, Hirudo, Pheretima, Zaocys, Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae, brewing grains white spirit are made, there is benefiting QI and nourishing blood, the merit of disperse blood stasis and dredge collateral, blood stagnancy due to deficiency of QI occurs after treating ischemia apoplexy hemiplegia, suffering limb weak and limp need not, the disease such as numb joint stuffiness, evident in efficacy.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme is described in further detail, but protection scope of the present invention is not limited only to this.
Embodiment 1
A kind of treat the Chinese medicinal liquor of hemiplegia after ischemia apoplexy, be made up of the crude drug of following portions by weight: the Radix Astragali 120 parts, Caulis Spatholobi 50 parts, Hirudo 8 parts, Pheretima 40 parts, Zaocys 30 parts, 30 parts of Rhizoma Gastrodiae, 50 parts, 50 ° brewing grains white spirits of Herba Aristolochiae Mollissimae 1200 parts.
The preparation method of the Chinese medicinal liquor of hemiplegia after described treatment ischemia apoplexy: add after the Radix Astragali, Caulis Spatholobi, Hirudo, Pheretima, Zaocys, Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae are all pulverized and mixed in container, add 50 ° of brewing grains white spirits, soak 30 days, isolate medicated liquor, to obtain final product.
Usage and dosage: oral, a 20ml, within 1st, take twice.
Embodiment 2
A kind of treat the Chinese medicinal liquor of hemiplegia after ischemia apoplexy, be made up of the crude drug of following portions by weight: the Radix Astragali 40 parts, Caulis Spatholobi 60 parts, Hirudo 6 parts, Pheretima 20 parts, Zaocys 20 parts, 12 parts of Rhizoma Gastrodiae, 40 parts, 60 ° brewing grains white spirits of Herba Aristolochiae Mollissimae 800 parts.
The preparation method of the Chinese medicinal liquor of hemiplegia after described treatment ischemia apoplexy: add after the Radix Astragali, Caulis Spatholobi, Hirudo, Pheretima, Zaocys, Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae are all pulverized and mixed in container, add 60 ° of brewing grains white spirits, soak 35 days, isolate medicated liquor, to obtain final product.
Usage and dosage: oral, a 20ml, within 1st, take twice.
Embodiment 3
A kind of treat the Chinese medicinal liquor of hemiplegia after ischemia apoplexy, be made up of the crude drug of following portions by weight: the Radix Astragali 240 parts, Caulis Spatholobi 40 parts, Hirudo 12 parts, Pheretima 60 parts, Zaocys 40 parts, 40 parts of Rhizoma Gastrodiae, 60 parts, 40 ° brewing grains white spirits of Herba Aristolochiae Mollissimae 5000 parts.
The preparation method of the Chinese medicinal liquor of hemiplegia after described treatment ischemia apoplexy: add after the Radix Astragali, Caulis Spatholobi, Hirudo, Pheretima, Zaocys, Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae are all pulverized and mixed in container, add 40 ° of brewing grains white spirits, soak 25 days, isolate medicated liquor, to obtain final product.
Usage and dosage: oral, a 20ml, within 1st, take twice.
Clinical trial
1.1 physical data
From in January, 2010 in February, 2016, hemiplegic patient screens after accepting ischemia apoplexy for medical treatment 100 examples.All cases is all made a definite diagnosis through the multiple inspection such as health check-up and head CT, and bad without organ functions such as serious liver, kidney, the hearts.And it is randomly divided into treatment group 50 example, the maleest 32 examples, female 18 example, age 26-70 year, 48.6 years old mean age.Matched group 50 example, the maleest 31 examples, female 19 example, age 27-71 year, 49 years old mean age.Two groups of patients all without significant difference (p 0.05) at the aspect such as age, the state of an illness, have comparability, refer to table 1.
1 liang of table group case ordinary circumstance compares
| Group (example) | Male/female | Mean age (year) | Basal ganglia region is blocked | Cerebellar infarction | Brain stem infarct |
| Treatment group (50) | 32/18 | 48.6 | 41 | 6 | 3 |
| Matched group (50) | 31/19 | 49 | 43 | 5 | 2 |
Note: two groups are compared: p 0.05.
1.2 diagnostic criteria
1. there are hypertension, diabetes or dyslipidemia medical history；2. there is the sings and symptoms of focal neurologic impairment, such as the symptom such as hemiplegia, hemidysesthesia；3. head CT shows: occur low-density focus in brain.
1.3 Therapeutic Method
Matched group: use western medicine routine treatment, regulates blood pressure irbesartan, regulates blood fat Atorvastatin calcium, and other take symptomatic treatment.
Treatment group: on the basis of matched group western medicine routine treatment, adds the Chinese medicinal liquor in the embodiment of the present invention 1, preparation method and using method.
After two groups are treated 8 weeks, before and after two groups of treatments, all carry out head CT inspection, observe clinical symptoms and improve situation.
1.4 therapeutic evaluation
The most effective: clinical symptoms significantly improves, limb function substantially recovers, and muscular strength is more than III grade.
The most effective: the more apparent improvement of clinical symptoms, limb function substantially recovers, and muscular strength is between II-III grade.
1.4.3 it is invalid: clinical symptoms is without improving, and limb function is without recovering, and muscular strength is below II grade.
1.5 statistical method
Data rate represents, uses x2Inspection, statistically significant for difference with p ＜ 0.05.
1.6 result
1.6.1 before and after treatment, two groups of clinical symptoms improvement situations compare:
Treatment group, on the basis of matched group is merely with western medicine routine treatment, adds Chinese medicinal liquor clinical symptoms improvement rate (93.98%) of the present invention, hence it is evident that be better than matched group and use merely clinical symptoms improvement rate (46.51%) after western medicine routine treatment, refer to table 2.
Before and after the group treatment of 2 liang of table, clinical symptoms improves number of cases and improvement rate
Note: improve=effective+effectively (p ＜ 0.05).
1.6.2
Untoward reaction
Two groups are showed no obvious adverse reaction during treating, but the functional defect person such as child, anemia of pregnant woman, hypertension and severe cardiac, liver, kidney, forbid the Chinese medicinal liquor taking in the present invention.
Model case
Case 1
Lee so-and-so, man, 58 years old, builder, Xi Xishao township Li Xi Shao Cun people.Go to a doctor with " hemiplegia after cerebral infarction " on May 16th, 2015.Patient during work, occurred suddenly that left limb was unable, dysphonia before 6 days.Once treated at this village health posts, less effective, therefore to seek medical advice at inventor.Disease is seen: dizzy, left limb limitation of activity, numbness of hand, aphasia, dimly red tongue, tongue is the most greasy, stringy and rolling pulse.Head CT shows: basal ganglia region, right side, the other cerebral infarction stove of ventricular anterior horn.
Dialectical Analyses: addiction delicious food savoury usually, in cause, burnt mistake is transported, accumulatively wet raise phlegm, and phlegm-damp is disturbed clear key, and the resistance of brain network numbness is obstructed, therefore sees dizziness, aphasia.Phlegm stagnating in meridian, QI and blood is obstructed, then see hemiplegia, numbness of hand.Tongue is the most greasy, stringy and rolling pulse be Sheng in phlegm-damp as.Dark tongue quality is the card of blood stasis of holding concurrently.
Diagnosis: apoplexy (phlegm stagnation in collateral)
The rule for the treatment of: replenishing QI to invigorate the spleen, reduces phlegm, and nourishes blood, disperse blood stasis and dredge collateral.
Side's medicine: the embodiment of the present invention 1 Chinese medicinal liquor and preparation method, using method.
Western medicine: 1. antiplatelet aggregation Bayaspirin.2. blood fat reducing Atorvastatin calcium.3. Neuroprotective Therapy in Treating Acute Edaravones etc., remaining gives symptomatic treatment.
After treating two weeks, dizzy disappearance, remaining all symptom all alleviates.After treating 6 weeks, hemiplegia, numbness of hand disappear, and speech is gradually clear and fully recovers.Advise and continue to take in the present invention embodiment 1 Chinese medicinal liquor 2 months to consolidate curative effect.By repeatedly following up a case by regular visits to, do not recur so far.
Case 2
Zhao so-and-so, man, 60 years old, peasant, was Qian Kou township, Nanyue County Bei Chouzhuan people from village, on March 19th, 2013, went to a doctor with " hemiplegia after cerebral infarction ", patient before 2 days during work, occur suddenly on the right side of myasthenia of limbs, aphasia.Once in county hospital, symptom gradually increases the weight of, and seeks medical advice at emergency inventor.Disease is seen: right half body limbs are unsuccessful, weak and limp unable, slurred speech, and the tip of the tongue is to the left, and tongue fur is white, dimly pale tongue, thready and hesitant pulse.Head CT shows: basal ganglia region, left side and left side occipital lobe cerebral infarction stove.
Dialectical Analyses: patient is worn with age, causes the deficiency of vital energy and blood vessels can not be agitated to run, and blood blocks, and stasis blocking brain arteries and veins is then shown in weak and limp unable, the tip of the tongue deflection of hemiplegia, limbs, aphasia.Dimly pale tongue, thready and hesitant pulse be blood stasis due to qi deficiency as.
Diagnosis: apoplexy (blood stasis due to qi deficiency)
The rule for the treatment of: benefiting QI and nourishing blood, disperse blood stasis and dredge collateral
Side's medicine: the embodiment of the present invention 1 Chinese medicinal liquor and preparation method, using method.
Western medicine: 1. blood fat reducing Atorvastatin calcium etc., 2. antiplatelet aggregation Bayaspirin, the 3. symptomatic treatment such as Neuroprotective Therapy in Treating Acute Edaravone.
After treating two weeks, hemiplegia, aphasia gradually recovers, and after treating 6 weeks, right side limb functional recover is normal, and speech understands, dispute has recovered the most to normally fully recovering.Advise and continue to take in the present invention embodiment 1 Chinese medicinal liquor 2 months to consolidate curative effect.By repeatedly following up a case by regular visits to, do not recur so far.
Claims (3)
1. treat the Chinese medicinal liquor of hemiplegia after ischemia apoplexy for one kind, it is characterized in that, be made up of the crude drug of following portions by weight: Radix Astragali 40-240 part, Caulis Spatholobi 40-60 part, Hirudo 6-12 part, Pheretima 20-60 part, Zaocys 20-40 part, Rhizoma Gastrodiae 12-40 part, Herba Aristolochiae Mollissimae 40-60 part, brewing grains white spirit 800-5000 part.
2. the Chinese medicinal liquor of hemiplegia after treatment ischemia apoplexy as claimed in claim 2, it is characterized in that, be made up of the crude drug of following portions by weight: the Radix Astragali 120 parts, Caulis Spatholobi 50 parts, Hirudo 8 parts, Pheretima 40 parts, Zaocys 30 parts, 30 parts of Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae 50 parts, brewing grains white spirit 1200 parts.
3. the preparation method of the Chinese medicinal liquor of hemiplegia after treatment ischemia apoplexy as claimed in claim 1 or 2, it is characterized in that: the Radix Astragali, Caulis Spatholobi, Hirudo, Pheretima, Zaocys, Rhizoma Gastrodiae, Herba Aristolochiae Mollissimae are all pulverized, add after mixing in container, add brewing grains white spirit, soak 25 ~ 35 days, isolate medicated liquor, to obtain final product.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112603968A (en) * | 2021-01-14 | 2021-04-06 | 刘光星 | Medicine for treating cardiovascular and cerebrovascular diseases |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861171A (en) * | 2006-04-18 | 2006-11-15 | 钟龙 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
| CN101194939A (en) * | 2007-12-07 | 2008-06-11 | 刘晓祥 | Chinese medicine prescription for treating early apoplexy and hemiplegia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861171A (en) * | 2006-04-18 | 2006-11-15 | 钟龙 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
| CN101194939A (en) * | 2007-12-07 | 2008-06-11 | 刘晓祥 | Chinese medicine prescription for treating early apoplexy and hemiplegia |
Non-Patent Citations (1)
| Title |
|---|
| 刘树增: "补阳还五汤加味治疗中风后遗症临床体会", 《湖南中医杂志》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603968A (en) * | 2021-01-14 | 2021-04-06 | 刘光星 | Medicine for treating cardiovascular and cerebrovascular diseases |
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