CN105770215A - Externally applied unguent for treating allergic dermatitis and preparation method thereof - Google Patents

Externally applied unguent for treating allergic dermatitis and preparation method thereof Download PDF

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CN105770215A
CN105770215A CN201610297858.8A CN201610297858A CN105770215A CN 105770215 A CN105770215 A CN 105770215A CN 201610297858 A CN201610297858 A CN 201610297858A CN 105770215 A CN105770215 A CN 105770215A
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allergic dermatitis
herba
herb
ointment
external
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张秀真
单学菊
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A61K36/855—Clerodendrum, e.g. glorybower
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses an externally applied unguent for treating allergic dermatitis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. Effective ingredients of the unguent provided by the invention are prepared from the following raw materials in parts by weight: folium isatidis, viburnum, repent pellionia herb, calamint, copperleaf herb, jave treebine herb, black nightshade herb, all-grass of linearleaf thustle, eriocarpous glochidion leaf, colebrookea, scabrous mosla herb, camphor-tree leaf, cunninghamia lanceolata, burmann cinnamon leaf, aristate goosefoot herb and sibirica walking fern herb. The externally applied unguent for treating the allergic dermatitis is formulated and prepared through finely selecting traditional Chinese medicinal materials which have the functions of clearing heat, detoxifying, cooling blood, removing ecchymosis, dispelling wind, killing insects, promoting blood circulation, deswelling, eliminating dampness, relieving itching and the like; all medicines are compatible, and can directly reach a pathological-change position; the externally applied unguent for treating the allergic dermatitis has the advantages of being quick in action, high in curative ratio, free from toxic and side effects and lasting in therapeutic effectiveness, being safe and convenient, and the like for treating symptoms of erythema, swell, papula, blister, bulla, fever and the like, which are caused by the allergic dermatitis, and is applicable to the popularization and the application of the clinical treatment and nursing of the allergic dermatitis.

Description

A kind of external-applied ointment treating allergic dermatitis and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of external-applied ointment treating allergic dermatitis and preparation method.
Background technology
Allergic dermatitis be skin or mucosa single or multiple contact exogenous material after, contact site even beyond position occur inflammatory reaction.Show as erythema, swelling, pimple, vesicle even bulla.
Allergic dermatitis performance is general without specificity.During mild, local is in erythema, light red to cerise, slightly edema, or has the big pimple of needle point intensive, and during serious symptom, erythema swelling is obvious, has most pimple, vesicle on this basis, bulla can occur during intense inflammation.Ruptured blister then has erosion, sepage and incrustation.As for strong primary stimulus, Epidermal necrosis made to come off, even deep and corium generation ulcer.When dermatitis betides tissue looseness position, as eyelid, lip, foreskin, scrotum etc. then swelling is obvious, in localized edema without clear and definite edge, glowing skin, superficial makings disappears.
The modal pruritis of allergic dermatitis can allow patient's sleeping and eating difficulty pacify, once increase the weight of, causes pruritus hard to bear, skin is scratched, erythema, sepage, erosion, even result in cutaneous necrosis, face caused serious harm.
At present, if the drug main hormone medicine for the treatment of allergic dermatitis, prolonged application hormone medicine, may occur in which the serious consequences such as central obesity, moon face, purple striae, thinning of skin, myasthenia, amyotrophy, edema, Nausea and vomiting, acne.For this, we are badly in need of developing external-applied ointment that a kind of safety has no side effect to help patient to break away from the misery that allergic dermatitis is brought.
Summary of the invention
The invention provides a kind of external-applied ointment treating allergic dermatitis and preparation method；The selected Chinese crude drug prescription with effects such as heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, wind dispelling insecticide, promoting blood circulation and detumescence, removing dampness to relieve itching of the present invention is concocted, all medicines are harmonious and can directly arrive diseased region, the advantages such as the erythema, swelling, pimple, vesicle, the bulla that cause for treatment allergic dermatitis, the symptom such as heating has instant effect, cure rate is high, have no side effect, safe ready, curative effect are lasting, are suitable to the popularization and application of allergic dermatitis clinical treatment and nursing.
For achieving the above object, technical scheme is implemented as follows:
A kind of external-applied ointment treating allergic dermatitis, make described ointment effective ingredient raw material composition and parts by weight be:
Make described ointment effective ingredient raw material composition and parts by weight be:
Make described ointment effective ingredient raw material composition and parts by weight be:
Make described ointment effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of external-applied ointment treating allergic dermatitis, comprises the following steps that:
(1) Folium Isatidis, pod, Herba Acalyphae, Herba Solani Nigri, Folium cinnamomi camphorae, Folium Cinnamomi burmannii and Herba Chenopodii Aristati are put in container, be firstly added 10-15 times amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract；Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts；Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts；United extraction liquid, filters, obtains filtrate standby；
(2) Herba Pellioniae repentis, Herba Clinopodii Polycephali, Herba Cissi Javanae and Herba Cirsii linearis are twisted respectively juice, filter impurity, stay juice, standby；
(3), after Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi), plumage calyx and Herba Camptosori Sibirici being ground into powder, immersing volumetric concentration is 90% alcoholic solution, stands 4 hours, takes out the supernatant, and the extractum precipitated is standby；
(4) Scabrous Mosla Herb and Lignum seu Ramulus Cunninghamiae Lanceolatae are placed in pot, heat with high heat, fry to surface coke black, internal coke yellow, spray 0.2 times amount clear water, take out, dry, grind into powder, obtained the fine powder of 160 orders, standby；
(5) step (1)-filtrate of (4) gained, juice, extractum and fine powder are mixed, add after vaseline, prepare for externally-applied soft ointment product, be the external-applied ointment of described treatment allergic dermatitis.
The property of medicine of Chinese medicine used by the present invention is as follows:
Folium Isatidis: bitter in the mouth, cold in nature；Return liver, the heart, stomach, spleen channel.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.The high hot excessive thirst of main calentura, coma, macule, spit blood, epistaxis, jaundice, dysentery, erysipelas, sore throat, aphtha, mumps.Modern medicine study confirms, Folium Isatidis water decoction is to staphylococcus aureus, and Staphylococcus albus, alpha streptococcus, meningococcus all have stronger inhibitory action；Diplococcus pneumoniae, hemophilus influenza and dysentery bacterium also there is certain inhibitory action.Folium Isatidis dilution factor more than 1: 100 kills leptospiral effect.Serogroup Icterohaemorrhagiae Walden type, nanukayami type also there is killing action.
Pod: sour in the mouth, cold nature.Dispelling wind detoxifies, and heat-clearing and toxic substances removing is invigorated blood circulation.Main anemopyretic cold, furuncle is generated heat, puerperal cold, injury and bone fracture.Tang Materia Medica carries: " main three worms, the therapeutic method to keep the adverse QI flowing downwards, rapid digestion of food.Boil branch juice and medicated porridge to raise children's, kill ascarid." modern medicine study confirmation, staphylococcus aureus, anthrax bacillus, diphtheria corynebacterium, bacillus pyocyaneus, group B streptococcus, friend enterobacteria, Bacillus typhi and dysentery bacterium are in vitro had inhibitory action in various degree by this product decoct.
Herba Pellioniae repentis: sweet in the mouth, micro-puckery, cool in nature；Return liver, the heart, spleen channel.Clearing away heat-damp and promoting diuresis, mind tranquilizing and the heart calming.Main damp and hot yellow cellulitis, ascites, insomnia, forgetful, allergic dermatitis, ulcer of the lower limb, furuncle toxic swelling.
Herba Clinopodii Polycephali: acrid in the mouth, hardship, cool in nature.Wind and heat dispersing, removing toxic substances and promoting subsidence of swelling, hemostasis.Main cold, fever, heatstroke, laryngopharynx swelling and pain, diphtheria, acute cholecystitis, hepatitis, enteritis, dysentery is scorching, dysentery, rib adenitis, mastitis, furuncle swelling toxin, allergic dermatitis, acute conjunctivitis, hematuria, metrorrhagia, gingival hemorrhage, traumatic hemorrhage.Guangzhou air force " conventional Chinese herbal medicine handbook " load: " clearing away heat-fire, promoting blood circulation and detumescence.Control acute cholecystitis, hepatitis, dysentery, parotitis, enteritis, hematuria, acute conjunctivitis, venom, innominate toxic swelling, mastitis, knife injury.”
Herba Acalyphae: bitter in the mouth, puckery, cool in nature；GUIXIN, lung, large intestine, small intestine meridian.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, removing food stagnancy.Main dysentery, has loose bowels, and spits blood, epistaxis, hematuria, metrorrhagia, infantile malnutrition, carbuncle furuncle infections, skin eczema." illustrated handbook planted by middle traditional Chinese medicines " carries: " painting mashed by fresh grass, controls dermatosis；Decoction, antitussive, control pneumonopathy.”
Herba Cissi Javanae: acrid in the mouth, warm in nature；Return lung, liver,spleen,kidney warp.Expelling wind and dampness, rattan stasis of blood pain relieving.Main air wets, eczema, skin pruritus, traumatic injury, rheumatic arthralgia.
Herba Solani Nigri: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Main furuncle, carbuncle, erysipelas, osteopatia sprain, chronic tracheitis, oedema due to nephritis." this sketch of the southern regions of the Yunnan Province is said " carries: " controls children's's ailment said due to cold or exposure, heat symptom-complex infantile convulsion, spasmolytic of reducing phlegm, also controls variolar carbuncle, pruritus due to wind pathogen all over.Furuncle, can attack and can dissipate.Leaf: wash skin ulcer." bacteriostatic test proves, staphylococcus aureus, dysentery bacterium, Bacillus typhi, Bacillus proteus, escherichia coli, bacillus pyocyaneus, hog cholera bacillus are all had certain bacteriostasis by Herba Solani Nigri decoct.
Herba Cirsii linearis: sour in the mouth, warm in nature.Promoting blood circulation to remove blood stasis, removing toxic substances and promoting subsidence of swelling.Main menoxenia, amenorrhea, dysmenorrhea, mastitis, traumatic injury, urinary tract infection, carbuncle furuncle, carbuncle, neurodermatitis, venom.
Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi): bitter in the mouth, puckery, property is put down；Return stomach, spleen, large intestine channel.Heat-clearing and toxic substances removing, removing dampness to relieve itching.Main Resina Toxicodendri verniciflui allergy, paddy field dermatitis, skin pruritus, urticaria, eczema, burn, mastitis, acute gastroenteritis, dysentery." Nanning City's medicine will " carries: " detumescence, pain relieving, dampness removing, removing blood stasis.Control traumatic injury, snakebite, paint erosion, skin ulcer scabies, dysentery." modern medicine study confirmation, this product decoct flat board paper disk method, staphylococcus aureus and bacillus pyocyaneus there are is inhibitory action.
Plumage calyx: acrid in the mouth, property is put down.Hemostasis, detoxifying and relieving itching.Main epistaxis, hemoptysis, traumatic hemorrhage, dermatitis, ringworm.
Scabrous Mosla Herb: acrid in the mouth, hardship, cool in nature.Dispelling wind to relieve the exterior syndrome, clearing away summer-heat is except temperature, detoxifying and relieving itching.Main headache due to common cold, cough, heatstroke, rubella is scorching, dysentery, hemorrhoidal bleeding, metrorrhagia, miliaria alba, eczema, limb tinea, snake bite and insect sting." Fujian traditional herbal medicine " carries: " dehumidifying is dispeled the wind.Treat eczema, relieving itching.”
Folium cinnamomi camphorae: acrid in the mouth, warm in nature；GUIXIN, spleen, lung meridian.Dispel the wind, dehumidifying, removing toxic substances, parasite killing.Main air pain of dampness syndrome, stomachache, burn due to hot liquid or fire, sore swollen toxin, chronic ulcer of the lower limb, scabies, skin pruritus, insect-bite." Nanning City's medicine will " carries: " dispel the wind, reduce phlegm, parasite killing.Control cold rheumatic osteopathia, stomachache.External treatment traumatic injury flutters wound, dissipates poison, circulation of qi promoting, pain relieving.”
Lignum seu Ramulus Cunninghamiae Lanceolatae: acrid in the mouth, slightly warm in nature.Return spleen, stomach warp.Ward off dirty, pain relieving, wet dissipation poison, subinverse gas.Control dermatitis rhus, rheumatism skin infection, beriberi, renal mass, trusted subordinate's distending pain.
Folium Cinnamomi burmannii: acrid in the mouth, micro-sweet, warm in nature；Return spleen, stomach warp.Expelling wind and removing dampness, antidiarrheal, hemostasis.Main itchy skin eruption, rheumatic arthralgia, to have loose bowels, dysentery is suffered from abdominal pain, constipation due to pathogenic cold toxic swelling and traumatic hemorrhage." south of the Five Ridges gather medicinal herbs record " load: " decocting water, married woman washes hair, and can dispel the wind；Ablution, can dissipate skin wind heat.”
Herba Chenopodii Aristati: lightly seasoned, property is put down.Invigorate blood circulation, regulating menstruation, dispelling wind for relieving itching.Main menorrhagia, dysmenorrhea, amenorrhea, allergic dermatitis, urticaria.
Herba Camptosori Sibirici: lightly seasoned, property is put down；GUIXIN warp.Blood circulation promoting and blood stasis dispelling, hemostasis, removing toxic substances.Main thromboangiitis obliterans, hemiplegia, metrorrhagia, traumatic hemorrhage, neurodermatitis, ulcer of the lower limb.
The present invention compared with prior art, has the advantages that
The selected Chinese crude drug prescription with effects such as heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, wind dispelling insecticide, promoting blood circulation and detumescence, removing dampness to relieve itching of the present invention is concocted, all medicines are harmonious and can directly arrive diseased region, the advantages such as the erythema, swelling, pimple, vesicle, the bulla that cause for treatment allergic dermatitis, the symptom such as heating has instant effect, cure rate is high, have no side effect, safe ready, curative effect are lasting, are suitable to the popularization and application of allergic dermatitis clinical treatment and nursing.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of ointment effective ingredient of the present invention forms and weight is:
The processing step of ointment preparation method of the present invention is:
(1) Folium Isatidis, pod, Herba Acalyphae, Herba Solani Nigri, Folium cinnamomi camphorae, Folium Cinnamomi burmannii and Herba Chenopodii Aristati are put in container, be firstly added 10-15 times amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract；Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts；Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts；United extraction liquid, filters, obtains filtrate standby；
(2) Herba Pellioniae repentis, Herba Clinopodii Polycephali, Herba Cissi Javanae and Herba Cirsii linearis are twisted respectively juice, filter impurity, stay juice, standby；
(3), after Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi), plumage calyx and Herba Camptosori Sibirici being ground into powder, immersing volumetric concentration is 90% alcoholic solution, stands 4 hours, takes out the supernatant, and the extractum precipitated is standby；
(4) Scabrous Mosla Herb and Lignum seu Ramulus Cunninghamiae Lanceolatae are placed in pot, heat with high heat, fry to surface coke black, internal coke yellow, spray 0.2 times amount clear water, take out, dry, grind into powder, obtained the fine powder of 160 orders, standby；
(5) step (1)-filtrate of (4) gained, juice, extractum and fine powder are mixed, add after vaseline, prepare for externally-applied soft ointment product, be the external-applied ointment of described treatment allergic dermatitis.
Usage and dosage: every day 3 times, each 3-6g, uniform application is in affected part.Within 5 days, it is a course for the treatment of, usual 1-3 the onset course for the treatment of.
Embodiment 2
The raw material of ointment effective ingredient of the present invention forms and weight is:
The ointment preparation method processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 3
The raw material of ointment effective ingredient of the present invention forms and weight is:
The ointment preparation method processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 4
The raw material of ointment effective ingredient of the present invention forms and weight is:
The ointment preparation method processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Clinical data:
1, case selection:
Selecting the allergic dermatitis patient 392 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group 196 example, wherein male 98 example, women 98 example, age 10-78 year, 42 years old mean age, the course of disease 1 week-5 years.Matched group 196 example, wherein male 98 example, women 98 example, age 15-68 year, 43 years old mean age, the course of disease 1 week-3 years.The course of disease of two groups of cases, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient's application external-applied ointment of the present invention, adult every day 3 times, each 3-6g, 5 days is a course for the treatment of, and usual 1-3 the course for the treatment of, effectively pertinacious disease needed 4-5 the course for the treatment of.
Matched group uses Pevisone, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: the transference cures such as skin erythema, swelling, pimple, vesicle, bulla, heating.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of external-applied ointment of the present invention, cure 130 examples, effective 63 examples, invalid 3 examples, cure rate 66.3%, total effective rate 98.5%.
Matched group is cured 40 examples, effective 51 examples, invalid 105 examples, cure rate 20.4%, total effective rate 46.4%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Chen, female, 60 years old, retired cadre, people from Liuzhou.There are the symptoms such as heating, fear of cold, shiver with cold, whole body redness macule in patient behind outer place before 3 years, after taking febrifuge and smearing ointment voluntarily, and DeGrain.Therefore to our hospital, it is diagnosed as allergic dermatitis.Being coated with after 1 course for the treatment of of external-applied ointment of the present invention, above-mentioned symptom takes a turn for the better；Continuing painting with 3 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom disappears and without cicatrix, follows up a case by regular visits to and does not recur so far.
2, certain is closed, man, 47 years old, electrician, people from Jilin songyuan.Occur after patient's tourism that red papules occurs in double; two forearm Exposure to Sunlight position, micro-itch, after spread to back, buttocks and femoribus internus, personal PIYANPING is coated with both hands, smears position pimple and take a favorable turn.To our hospital, it is diagnosed as allergic dermatitis.2 courses for the treatment of of rear painting external-applied ointment of the present invention, above-mentioned symptom takes a turn for the better；Continuing painting with 2 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom is wholly absent, and follows up a case by regular visits to and does not recur.
3, Shen, female, 38 years old, sells, people from Zhangjiajie, Hunan.Patient has chronic facial cosmetic dermatitis allergies.Afterwards because of free and at leisure from smearing " eye shadow ", cause red swelling of the skin, pain companion's pruritus, have slight desquamation.To our hospital, it is diagnosed as allergic dermatitis.Giving painting external-applied ointment of the present invention 2 courses for the treatment of, above-mentioned symptom alleviates；Continuing painting with 2 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom disappears, and recovery from illness is not recurred.
4, she certain, man, 30 years old, self-employed entrepreneurs, Zhangzhou, Fujian people.The symptoms such as patient vesicle occurred, oozes out after both hands contact explosive powder before 2 years, pruritus.To our hospital, give to be coated with outside allergic dermatitis cream, DeGrain.After 1 course for the treatment of of rear replacing painting external-applied ointment of the present invention, above-mentioned symptom alleviates；Continuing painting with 2 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom is wholly absent, and follows up a case by regular visits to and does not recur.
5, field, man, 25 years old, cook, From Anshun of Guizhou people.There are the symptoms such as red swelling of the skin is scorching hot, pain, pruritus, tight sense in 2 years causes of patient too much edible seafood, after increase the weight of gradually.Then to our hospital, it is diagnosed as allergic dermatitis on inspection.Being coated with 1 course for the treatment of of external-applied ointment of the present invention, above-mentioned symptom takes a turn for the better；Continuing painting with after 3 courses for the treatment of of external-applied ointment of the present invention, above-mentioned symptom all disappears, and follows up a case by regular visits to and does not recur.
6, river, female, 18 years old, student, people from Laiwu in Shandong province.Patient because skin care item improper use causes allergic dermatitis, did not take an evident turn for the better before 1 year after local hospital is treated, then to our hospital.Being coated with after 1 course for the treatment of of external-applied ointment of the present invention, allergic dermatitis symptom takes a turn for the better；Continuing painting with after 2 courses for the treatment of of external-applied ointment of the present invention, allergic dermatitis symptom all disappears, and follows up a case by regular visits to and does not recur.

Claims (5)

1. the external-applied ointment treating allergic dermatitis, it is characterised in that: make described ointment effective ingredient raw material composition and parts by weight be:
2. a kind of external-applied ointment treating allergic dermatitis according to claim 1, it is characterised in that: make described ointment effective ingredient raw material composition and parts by weight be:
3. a kind of external-applied ointment treating allergic dermatitis according to claim 1, it is characterised in that: make described ointment effective ingredient raw material composition and parts by weight be:
4. a kind of external-applied ointment treating allergic dermatitis according to claim 1, it is characterised in that: make described ointment effective ingredient raw material composition and parts by weight be:
5. the preparation method of the external-applied ointment of the treatment allergic dermatitis as described in any one of claim 1-4, it is characterised in that: comprise the following steps that:
(1) Folium Isatidis, pod, Herba Acalyphae, Herba Solani Nigri, Folium cinnamomi camphorae, Folium Cinnamomi burmannii and Herba Chenopodii Aristati are put in container, be firstly added 10-15 times amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract；Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts；Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts；United extraction liquid, filters, obtains filtrate standby；
(2) Herba Pellioniae repentis, Herba Clinopodii Polycephali, Herba Cissi Javanae and Herba Cirsii linearis are twisted respectively juice, filter impurity, stay juice, standby；
(3), after Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi), plumage calyx and Herba Camptosori Sibirici being ground into powder, immersing volumetric concentration is 90% alcoholic solution, stands 4 hours, takes out the supernatant, and the extractum precipitated is standby；
(4) Scabrous Mosla Herb and Lignum seu Ramulus Cunninghamiae Lanceolatae are placed in pot, heat with high heat, fry to surface coke black, internal coke yellow, spray 0.2 times amount clear water, take out, dry, grind into powder, obtained the fine powder of 160 orders, standby；
(5) step (1)-filtrate of (4) gained, juice, extractum and fine powder are mixed, add after vaseline, prepare for externally-applied soft ointment product, be the external-applied ointment of described treatment allergic dermatitis.
CN201610297858.8A 2016-04-29 2016-04-29 Externally applied unguent for treating allergic dermatitis and preparation method thereof Pending CN105770215A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068502A (en) * 2010-12-12 2011-05-25 任国祚 Skin anti-inflammation and itching relieving ointment
CN103223132A (en) * 2013-05-17 2013-07-31 陈孔春 Medicine for treating allergic dermatitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068502A (en) * 2010-12-12 2011-05-25 任国祚 Skin anti-inflammation and itching relieving ointment
CN103223132A (en) * 2013-05-17 2013-07-31 陈孔春 Medicine for treating allergic dermatitis and preparation method thereof

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