CN105769329B - Disposable squash type alkali metal injection device - Google Patents
Disposable squash type alkali metal injection device Download PDFInfo
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- CN105769329B CN105769329B CN201410818356.6A CN201410818356A CN105769329B CN 105769329 B CN105769329 B CN 105769329B CN 201410818356 A CN201410818356 A CN 201410818356A CN 105769329 B CN105769329 B CN 105769329B
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- alkali metal
- memotron
- injection
- bolt
- objective table
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Abstract
The present invention relates to a kind of disposable squash type alkali metal injection device, including alkali metal memotron, alkali metal fluid, protection liquid, injection needle and injection control unit;One end of the injection needle is angle, and the other end is flat mouth, and connection overcoat is provided with outside one end of flat mouth, and the injection needle is connected with one end of alkali metal memotron and connects overcoat and is enclosed on outside connecting portion;The other end of alkali metal memotron is connected with the injection control unit;The alkali metal fluid and protection liquid are placed in alkali metal memotron.Device proposed by the present invention, alkali metal need not take out from storage container when in use, but can be used after alkali metal memotron directly is connected into injection needle and injection device, reduce the risk of alkali metal and air contact, convenience in transport and storage.Alkali metal memotron is disposable product, and every alkali metal memotron is only equipped with micro alkali metal, avoids the potential safety hazard brought because storing a large amount of alkali metal for a long time.
Description
Technical field
The invention belongs to medical instruments field, and in particular to a kind of that medium is introduced to internal apparatus with injection system.
Background technology
High temperature heating ablation is an important channel of tumor physical therapy, but is existed including radio frequency, microwave, laser, ultrasound
Interior traditional heating pattern can be to organizing to cause to scald on the way when energy is transported into deep tumor, and many equipment are complicated high
It is expensive.Alkali metal heat therapy breaks through traditional technique for hyperthermia theory, micro- by injecting by naturally occurring water environment in destination organization
Sodium, potassium or its alloy fluid of amount produce strong heat-producing chemical reaction, so as to reach efficient heating ablation purpose.
But just because of the above-mentioned characteristic of alkali metal, also alkali metal thermotherapy is caused certain safety risks to be present, in reality
Na-K alloy must be avoided to be contacted with air or water in the application of border.Na-K alloy is liquid at room temperature, can use syringe
Be expelled to target area, but ordinary syringe using when be required for first drawing alkali metal fluid, and poor sealing, this nothing
Doubt the risk for adding alkali metal and air contact.In addition, alkali metal be expelled in vivo before had always a demand for protect liquid every
Exhausted air, while micro alkali metal is only needed every time in actual applications, these are all that ordinary syringe institute is unappeasable.
The content of the invention
(1) technical problems to be solved
The purpose of the present invention is for the problems of alkali metal technique for hyperthermia, there is provided a kind of simple to operate, safe
Disposable squash type room temperature liquid alkali metal injection device.
(2) technical scheme
The purpose of the present invention is achieved through the following technical solutions:
A kind of disposable squash type alkali metal injection device, including alkali metal memotron, alkali metal
Fluid, protection liquid, injection needle and injection control unit;
Closed at both ends using preceding alkali metal memotron, alkali metal fluid and protection liquid are placed in alkali metal memotron;Make
Used time, one end was connected with injection needle;
One end of the injection needle is angle, and the other end is flat mouth, and connection overcoat, the note are provided with outside one end of flat mouth
Penetrate pin and be connected with one end of alkali metal memotron and connect overcoat and be enclosed on outside connecting portion;Alkali metal memotron does not connect injection
Pin is partially disposed in injection control unit.
Injection control unit is used to control the alkali metal forward fluid motion in alkali metal memotron, and the mode of control can adopt
With the mode to the extruding of alkali metal memotron concora crush or rolling extrusion.
Wherein, the injection control unit includes bolt, extrudate, objective table and bolt fixed station, on the objective table
Extrudate, vertical or rolling extrusion alkali metal flow of fluid are set.
As one of the preferred technical solution of the present invention, wherein, the injection control unit includes bolt, extrudate, spiral shell
Bolt fixed station and objective table, objective table and bolt fixed station are configured to reeded structure, and bolt fixed station is located at groove structure
Top, the lower end in contact of the extrudate of rectangular shape, extrudate top surface and bolt is set in groove;The bolt fixed station
On be provided with screw, the bolt is connected by screw with bolt fixed station.
Alkali metal memotron is placed between objective table and extrudate, and extrudate is pressed down against alkali metal with the rotation of bolt
Memotron.
As another optimal technical scheme of the present invention, it is provided with the objective table and places the recessed of alkali metal memotron
Groove, objective table top are provided with bolt fixed station, columned extrudate are placed between objective table and bolt fixed station.Objective table
It is bolted with bolt fixed station.Alkali metal memotron is placed between objective table and extrudate, with the rolling of extrudate
Extrude alkali metal memotron.
Preferably, the objective table projection of shape is rectangle, and major axis is the region for the groove for placing alkali metal memotron.
Further, the disposable squash type alkali metal injection device can judge alkali gold by measuring resistance variations
Whether category fluid all releases injection needle.The disposable squash type alkali metal injection device also includes resistance measurement device, institute
A measurement end for stating resistance measurement device is placed on by angle one end of injection needle in 1-5mm distances, another measurement end with
The flat mouth end thereof contacts of injection needle.
As another optimal technical scheme of the present invention, the disposable property squash type alkali metal injection device can profit
Alkali metal flow of fluid is promoted with electric field, now, there is a conductive filament in alkali metal memotron, along axis through whole storage
Pipe is deposited, when injection needle is connected with alkali metal memotron, conductive filament is connected with stainless steel needle tubing.Conductive filament in alkali metal memotron
Voltage source negative pole is connect, pin electrode connects voltage source positive pole, and pin electrode and injection needle are inserted in tissue, and pin electrode is placed on injection needle
Angle one end by 1-5mm distances, voltage range is for 2V-6V between, under electric field action, drives alkali metal fluid from negative pole
Moved to positive pole one end.
Wherein, the alkali metal fluid is Na-K alloy, and the mass ratio of sodium potassium is 1 in the Na-K alloy:0.8-9.
Wherein, the protection liquid is that to have biocompatibility is to remove the organic solvent of moisture removal, selected from olive oil, peanut
One or more in oil, soybean oil, rapeseed oil and glycerine.
Wherein, in alkali metal memotron, the protection liquid is placed on alkali metal fluid both sides.
Wherein, the alkali metal memotron is silicone tube, internal diameter 0.1-2.0mm.
Wherein, the injection needle has 1-5 roots.The setting of injection needle more than two, in use, connection alkali metal memotron
Stainless-steel pipe insert respectively in target tissue, compared with single-point is injected, increase the effective range of alkali metal thermotherapy.
(3) beneficial effect
Disposable squash type alkali metal injection device proposed by the present invention, alkali metal need not be from storage container when in use
Middle taking-up, but can be used after alkali metal memotron directly is connected into injection needle and injection device, reduce alkali metal and sky
The risk of gas contact.Meanwhile Na-K alloy is sealed in the alkali metal memotron of protection liquid, convenience in transport and storage.Alkali gold
Category memotron is disposable product, and every alkali metal memotron is only equipped with micro alkali metal, is avoided because long-term storage is big
The potential safety hazard measured alkali metal and brought.
Brief description of the drawings
Fig. 1 is the structural representation of alkali metal memotron;
Fig. 2 is injection needle structural representation;
Fig. 3 (a) is the injection control apparatus front view for taking concora crush mode;
Fig. 3 (b) is the injection control apparatus side view for taking concora crush mode;
Fig. 3 (c) is the injection control apparatus top view for taking concora crush mode;
Fig. 4 is the operation chart for taking concora crush mode to extrude alkali metal memotron;
Fig. 5 (a) is the injection control apparatus structure front view for taking rolling extrusion mode;
Fig. 5 (b) is the injection control apparatus structure right view for taking rolling extrusion mode;
Fig. 5 (c) is the injection control apparatus structure upward view for taking rolling extrusion mode;
Fig. 6 is the operation chart for taking rolling extrusion mode to extrude alkali metal memotron;
Fig. 7 (a) is the operation chart that alkali metal fluid is promoted using electric field;
Fig. 7 (b) is alkali metal memotron profile when promoting alkali metal fluid using electric field;
Fig. 8 is multi-point injection alkali metal thermotherapy schematic diagram.
In figure:1 is alkali metal memotron, and 2 be alkali metal fluid, and 3 be protection liquid, and 4 be connection inner sleeve, and 5 be stainless pin
Pipe, 6 be connection overcoat, and 7 be objective table, and 8 be bolt fixed station, and 9 be extrudate, and 10 be bolt, and 11 be target tissue, and 12 be spiral shell
Bar, 13 be nut, and 14 be through hole, and 15 be pin electrode, and 16 be conductive filament, and 17 be voltage source.
Embodiment
With reference to the accompanying drawings and examples, the embodiment of the present invention is described in further detail.Implement below
Example is used to illustrate the present invention, but is not limited to the scope of the present invention.
Embodiment 1 takes concora crush mode to extrude alkali metal memotron
The disposable squash type alkali metal injection device of this example, as shown in Figure 1, Figure 2, Figure 3 shows, by alkali metal memotron 1, alkali
Metal fluid 2, protection liquid 3, injection needle and injection control apparatus collectively constitute.Alkali metal memotron 1 is with certain elasticity
Silicone tube, protection liquid 3, alkali metal fluid 2 and protection liquid 3 are sequentially arranged with pipe.Alkali metal fluid 2 is sodium potassium mass ratio 1:3
Na-K alloy, protection liquid 3 is to remove the olive oil of moisture removal.Closed at both ends using preceding alkali metal memotron 1, interior diameter is
0.4mm.One end is connected with injection needle during use.The one end of alkali metal memotron 1 is wrapped with connection inner sleeve 4, and the connection outer wall of inner sleeve 4 has ditch
Groove, for connecting the connection overcoat on injection needle.Injection needle includes stainless steel needle tubing 5 and connection overcoat 6, stainless steel needle tubing 5 one
End is angle, and one end is flat mouth, has connection overcoat 6 on the outside of tack one end, has projection on the inside of connection overcoat.
The mode of concora crush is taken in the control of injection needle, and injection control apparatus includes objective table 7, bolt fixed station 8, extrudate
9 and bolt 10.Objective table 7 and bolt fixed station are connected as reeded structure, and (see Fig. 3 (b), side projection is shaped as rotating
90 ° " recessed " word), top is divided into bolt fixed station 8.Bolt 10 passes through bolt fixed station 8, and tail end is contacted with extrudate 9, passed through
Rotation adjustment the distance between the extrudate 9 and objective table 7 of bolt 10.Extrudate 9 is one cube of module, the top surface of extrudate 9
With the lower end in contact of bolt;There is a blind hole with threaded bolt contacts place.Extrudate bottom surface contacts with alkali metal memotron 1.
As shown in figure 4, in use, connection injection needle and alkali metal memotron 1, the flat mouth one end of stainless steel needle tubing 5 are inserted first
Enter in alkali metal memotron 1.Then be partially placed into injection control apparatus of the rear end of alkali metal memotron 1 equipped with protection liquid 3 is carried
Between thing platform 7 and extrudate 9 and fix, rotating bolt 10, alkali metal memotron 1 is extruded so as to push away by the rotation of bolt 10
Alkali metal fluid 2 flows to syringe needle in dynamic pipe.When the angle one end of stainless steel needle tubing 5 has protection liquid 3 to flow out, injection needle is inserted
11 in tissue, rotating bolt 10 is further continued for, until 2 completely out syringe needle of alkali metal fluid is entered in target tissue 11, is completed
The process of alkali metal heating ablation.
Embodiment 2:Rolling extrusion mode is taken to extrude alkali metal memotron
The disposable squash type alkali metal injection device of this example, as shown in Figure 1, Figure 2, Figure 5, by alkali metal memotron 1, alkali
Metal fluid 2, protection liquid 3, injection needle and injection control apparatus collectively constitute.Alkali metal memotron 1, alkali metal fluid 2, protect
The setting for protecting liquid 3 is same as Example 1.
The mode of rolling extrusion is taken in the control of injection needle, and injection control apparatus includes objective table 7, bolt fixed station 8, squeezed
Press thing 9 and bolt 10.Objective table 7 is a spill platform, there is the groove of semi-cylindrical, radian and alkali metal memotron 1 along axis
It coincide, depth is equal to the path length of alkali metal memotron 1 half, and effect is to prevent alkali metal memotron 1 from occurring during rolling extrusion
It is mobile.Bolt fixed station 8 is connected, and pass through bolt per side with two fixed screw rods 12 with objective table 7 in the both sides of objective table 7
The distance between the adjustment of nut 13 of the top of fixed station 8 and objective table 7, there is equidistant through hole 14 on bolt fixed station 8.Extrudate
9 be a roller, is fixed on the center of objective table 7, there is side arm at roller both ends, ridden between objective table 7 and bolt fixed station 8.
As shown in fig. 6, injection needle and alkali metal memotron 1 are connected first, the flat mouth one end of stainless steel needle tubing 5 insertion alkali metal
In memotron 1.Then the rear end of alkali metal memotron 1 is partially placed into the recessed of injection control apparatus objective table 7 equipped with protection liquid 3
In groove, the distance between the adjustment bolt fixed station 8 of nut 13 and objective table 7 on rotation screw rod 12 so that the roller of extrudate 9 is firm
It can rotate well.In use, the side arm of pushing rolling wheels both sides so that roller rolling extrusion alkali metal memotron 1 is so as to promoting pipe
Interior alkali metal fluid 2 is flowed to syringe needle, it is necessary to during fixed idler whell position, with bolt 10 through the through hole 14 on bolt fixed station,
Rotating bolt pinch rollers side arm.When the angle one end of stainless steel needle tubing 5 has protection liquid 3 to flow out, injection needle is inserted in tissue
11, pushing rolling wheels are further continued for, until 2 completely out syringe needle of alkali metal fluid is entered in target tissue 11, complete alkali metal heat
The process of ablation.
The injection device of the present invention can also judge injection process with resistance metering system.Specially by injection needle and resistance
The pin electrode insertion target tissue 11 of measuring instrument, injects needle tip and pin electrode distance closely but does not contact.Measure stainless
The flat mouth one end of draw point pipe 5 judges the process injected to the resistance variations between pin electrode.
Embodiment 3
This injection device, electric field can also be utilized to promote alkali metal fluid 2 to flow, as shown in Fig. 7 (a) and (b), now,
There is a conductive filament 16 in alkali metal memotron 1, run through whole alkali metal memotron 1 along axis, when injection needle and alkali gold
When belonging to the connection of memotron 1, conductive filament 16 is connected with stainless steel needle tubing 5.In use, conductive filament 16 meets 6V in alkali metal memotron 1
The negative pole of voltage source 17, pin electrode 15 connects the positive pole of voltage source 17.Pin electrode 15 and stainless steel needle tubing 5 are inserted in tissue, pin electricity
Pole 15 is placed on by angle one end of stainless steel needle tubing 5 in 1-5mm distances, and alkali metal fluid 2 is under electric field driven effect from negative
Moved to positive pole one end pole.
Embodiment 4:Multi-point injection alkali metal thermotherapy
In this embodiment, fashion of extrusion, injection control apparatus and embodiment one are identical.As shown in figure 8, in use,
The stainless-steel pipe 5 of connection alkali metal memotron has 3, inserts respectively in target tissue, compared with single-point is injected, increases alkali
The effective range of metal thermotherapy.
In summary, the invention provides a kind of disposable squash type room temperature liquid alkali metal note simple to operate, safe
Injection device.The invention enables alkali metal thermotherapy implement when directly by alkali metal memotron and injection needle, note equipped with alkali metal
Penetrate i.e. usable after control device connection, operation is simple and reliable, and alkali metal memotron during transport and use all
With extraordinary security.
Finally it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although reference
The present invention is described in detail for preferred embodiment, it will be appreciated by those skilled in the art that can be to the technical side of the present invention
Case is modified or equivalent substitution, and without departing from the spirit and scope of technical solution of the present invention, it should cover in this hair
Among bright right.
Claims (9)
- A kind of 1. disposable squash type alkali metal injection device, it is characterised in that including alkali metal memotron, alkali metal fluid, Protect liquid, injection needle and injection control unit;Closed at both ends using preceding alkali metal memotron, alkali metal fluid and protection liquid are placed in alkali metal memotron;During use One end is connected with injection needle;One end of the injection needle is angle, and the other end is flat mouth, and connection overcoat, the injection needle are provided with outside one end of flat mouth It is connected with one end of alkali metal memotron and connects overcoat and is enclosed on outside connecting portion;Alkali metal memotron does not connect injection needle It is partially disposed in injection control unit.
- 2. injection device according to claim 1, it is characterised in that it is described injection control unit include bolt, extrudate, Objective table and bolt fixed station, extrudate is set on the objective table, and the mode of the extrudate extruding alkali metal memotron is Concora crush or rolling extrusion.
- 3. according to the injection device described in any one of claim 1 or 2, it is characterised in that the injection control unit includes spiral shell Bolt, extrudate, bolt fixed station and objective table, objective table and bolt fixed station are configured to reeded structure, bolt fixed station The lower end in contact of the extrudate of rectangular shape, extrudate top surface and bolt is set in the top of groove structure, groove;Institute State and screw is provided with bolt fixed station, the bolt is connected by screw with bolt fixed station.
- 4. injection device according to claim 1 or 2, it is characterised in that the injection control unit includes bolt, extruding Thing and objective table, the groove for placing alkali metal memotron is provided with the objective table, and being provided with bolt above objective table fixes Platform, columned extrudate is placed between objective table and bolt fixed station;Objective table and bolt fixed station are bolted.
- 5. injection device according to claim 1, it is characterised in that the injection control unit includes 2-6V voltage sources, Voltage source is connected with positive pole and negative pole, and the positive pole and negative pole are wire, and positive pole is inserted in alkali metal memotron.
- 6. injection device according to claim 1, it is characterised in that characterized in that, the alkali metal fluid is sodium potassium Alloy;The mass ratio of sodium potassium is 1 in the Na-K alloy:3.
- 7. injection device according to claim 1, it is characterised in that the protection liquid be have biocompatibility to go The organic solvent of moisture removal, the one or more in olive oil, peanut oil, soybean oil, rapeseed oil and glycerine.
- 8. according to the injection device described in claim 1-2 and claim any one of 5-7, it is characterised in that the alkali metal Memotron is silicone tube, internal diameter 0.1-2.0mm;In alkali metal memotron, the protection liquid is placed on alkali metal fluid two Side.
- 9. according to the injection device described in claim 1-2 and claim any one of 5-7, it is characterised in that the injection needle There are 1-5 roots.
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CN201410818356.6A CN105769329B (en) | 2014-12-24 | 2014-12-24 | Disposable squash type alkali metal injection device |
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CN201410818356.6A CN105769329B (en) | 2014-12-24 | 2014-12-24 | Disposable squash type alkali metal injection device |
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CN105769329A CN105769329A (en) | 2016-07-20 |
CN105769329B true CN105769329B (en) | 2018-02-23 |
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CN107007834A (en) * | 2017-05-10 | 2017-08-04 | 苏州万化集成生物科技有限公司 | Tumor thermotherapy pill and its preparation facilities, preparation technology |
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US4525164A (en) * | 1981-04-24 | 1985-06-25 | Biotek, Inc. | Wearable medication infusion system with arcuated reservoir |
US5549569A (en) * | 1994-02-15 | 1996-08-27 | Lawrence A. Lynn | Ex vivo blood isolation system |
CN2366119Y (en) * | 1999-04-28 | 2000-03-01 | 杨忠 | Electrically driven infusion device |
CN202314718U (en) * | 2011-11-17 | 2012-07-11 | 山东大学 | Flexible microinjector |
CN202802347U (en) * | 2012-10-24 | 2013-03-20 | 王双燕 | Zero gravity infusion apparatus |
CN203043144U (en) * | 2013-01-12 | 2013-07-10 | 张艳 | Rapid blood transfusion pressurizing device for puerperae |
CN203169735U (en) * | 2013-04-29 | 2013-09-04 | 德州市第二中学 | Extruding intravenous injector |
CN203183417U (en) * | 2013-04-10 | 2013-09-11 | 杨力 | Zero-gravity infusion apparatus |
-
2014
- 2014-12-24 CN CN201410818356.6A patent/CN105769329B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4525164A (en) * | 1981-04-24 | 1985-06-25 | Biotek, Inc. | Wearable medication infusion system with arcuated reservoir |
US5549569A (en) * | 1994-02-15 | 1996-08-27 | Lawrence A. Lynn | Ex vivo blood isolation system |
CN2366119Y (en) * | 1999-04-28 | 2000-03-01 | 杨忠 | Electrically driven infusion device |
CN202314718U (en) * | 2011-11-17 | 2012-07-11 | 山东大学 | Flexible microinjector |
CN202802347U (en) * | 2012-10-24 | 2013-03-20 | 王双燕 | Zero gravity infusion apparatus |
CN203043144U (en) * | 2013-01-12 | 2013-07-10 | 张艳 | Rapid blood transfusion pressurizing device for puerperae |
CN203183417U (en) * | 2013-04-10 | 2013-09-11 | 杨力 | Zero-gravity infusion apparatus |
CN203169735U (en) * | 2013-04-29 | 2013-09-04 | 德州市第二中学 | Extruding intravenous injector |
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