CN105769329B - Disposable injection device of extruded alkali metal - Google Patents

Disposable injection device of extruded alkali metal Download PDF

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Publication number
CN105769329B
CN105769329B CN201410818356.6A CN201410818356A CN105769329B CN 105769329 B CN105769329 B CN 105769329B CN 201410818356 A CN201410818356 A CN 201410818356A CN 105769329 B CN105769329 B CN 105769329B
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alkali metal
injection
needle
bolt
tube
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CN201410818356.6A
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CN105769329A (en
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王倩
刘静
周欣
周一欣
陈柏炜
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中国科学院理化技术研究所
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Abstract

本发明涉及一种一次性挤压式碱金属注射装置,包括碱金属储存管、碱金属流体、保护液、注射针以及注射控制部件;所述注射针的一端为斜口,另一端为平口,平口的一端外设置有连接外套,所述注射针与碱金属储存管的一端连接且连接外套套在连接部位外;碱金属储存管的另一端与所述注射控制部件连接;所述碱金属流体和保护液放置在碱金属储存管中。 The present invention relates to a disposable injection device squeeze an alkali metal, an alkali metal reservoir comprises a tube, the fluid an alkali metal, protection liquid, an injection needle and an injection control means; end of the needle is beveled, and the other end is flat, an outer end provided with a flat connecting outer end, the injection needle with an alkali metal storage tube is connected to the outer sleeve and the outer connector connection portion; alkali metal reservoir and the other end is connected to the injection tube control member; said fluid an alkali metal and protection was placed in an alkali metal storage tube. 本发明提出的装置,在使用时碱金属不需要从储存容器中取出,而是直接将碱金属储存管连接注射针和注射装置后即可使用,减少了碱金属和空气接触的风险,方便运输和储存。 Means proposed by the invention, the alkali metal in use need not removed from the reservoir, but directly to the store to use an alkali metal pipe connecting the needle and the injection device, and reduces the risk of an alkali metal in contact with air, easy to transport and storage. 碱金属储存管为一次性用品,且每只碱金属储存管只装有微量的碱金属,避免了因长期储存大量碱金属而带来的安全隐患。 Alkali metal storage tube is one-time items, and each alkali metal storage tube containing only trace amounts of alkali metal, to avoid the long-term storage due to a large number of alkali metal and potential safety problems.

Description

一次性挤压式碱金属注射装置 Disposable injection device of extruded alkali metal

技术领域 FIELD

[0001] 本发明属于医疗器械领域,具体涉及一种以注射方式将介质引入体内的器械。 [0001] The present invention belongs to the field of medical devices, particularly, to a medium by injection into the body of the instrument.

背景技术 Background technique

[0002] 高温热消融是肿瘤物理治疗的一条重要途径,但是包括射频、微波、激光、超声在内的传统加热模式在将能量输往深部肿瘤时会对沿途组织造成烫伤,且不少设备复杂昂贵。 [0002] The high temperature thermal ablation therapy is an important way of physical tumors, conventional heating mode includes a radio frequency, microwave, laser, ultrasonic energy, including when exported deep tumors would cause burns along the tissue, a lot of equipment and complex expensive. 碱金属热疗法突破传统热疗技术理念,借助目标组织内天然存在的水环境,通过注射微量的钠、钾或其合金流体产生强烈的放热化学反应,从而达到高效的热消融目的。 Alkali metal hyperthermia thermotherapy break the traditional technical idea, by means of naturally occurring target tissue environment of water, a strong exothermic chemical reaction by microinjection of sodium, potassium or an alloy thereof the fluid, so as to achieve efficient thermal ablation purposes.

[0003] 但是,正是由于碱金属的上述特性,也使得碱金属热疗存在一定安全性隐患,在实际应用中一定要避免钠钾合金与空气或水接触。 [0003] However, the above characteristic is an alkali metal, an alkali metal makes certain security risks hyperthermia, in practical applications must avoid sodium-potassium alloy is contacted with air or water. 钠钾合金在室温下是液态,可以用注射器注射到靶向区域,但是普通注射器使用时都需要先吸取碱金属流体,而且密封性不好,这无疑增加了碱金属和空气接触的风险。 Sodium potassium alloy is liquid at room temperature, can be injected with a syringe into the targeted region, but all need to draw the alkali metal when an ordinary syringe using the fluid, and sealing is not good, it will increase the risk of an alkali metal and contact with air. 另外,碱金属在注射到体内之前一直需要有保护液隔绝空气,同时在实际应用中每次只需要微量的碱金属,这些都是普通注射器所不能满足的。 Further, the alkali metal prior to injection into the body fluid has been isolated from the air requires protection, while in practical applications a time trace amounts of alkali metals, which are not met by an ordinary syringe.

发明内容 SUMMARY

[0004] (一)要解决的技术问题 [0004] (a) To solve technical problems

[0005] 本发明的目的是针对碱金属热疗技术所存在的问题,提供一种操作简单、安全的一次性挤压式室温液态碱金属注射装置。 Simple [0005] The object of the present invention is directed to an alkali metal Hyperthermia the problems, there is provided a method of operating, squeeze safe disposable injection device rt liquid alkali metal.

[0006] (二)技术方案 [0006] (ii) Technical Solution

[0007] 本发明的目的通过以下技术方案来实现: [0007] The object of the present invention is achieved by the following technical solutions:

[0008] —种一次性挤压式碱金属注射装置,包括碱金属储存管、碱金属 [0008] - The disposable squeeze type alkali metal injection apparatus, comprising a storage tube alkali metal, an alkali metal

[0009] 流体、保护液、注射针以及注射控制部件; [0009] fluid, the protection liquid, an injection needle and an injection control means;

[0010] 使用前碱金属储存管两端封闭,碱金属流体和保护液放置在碱金属储存管中;使用时一端与注射针连接; [0010] prior to use an alkali metal storage tube closed at both ends, and an alkali metal protection liquid fluid is placed in an alkali metal storage tube; one end connected to the injection needle during use;

[0011] 所述注射针的一端为斜口,另一端为平口,平口的一端外设置有连接外套,所述注射针与碱金属储存管的一端连接且连接外套套在连接部位外;碱金属储存管没有连接注射针的部分放置在注射控制部件中。 [0011] The end of the needle is beveled, and the other end is flat, the outer end flat is provided with one end connected to the jacket, the injection needle with an alkali metal storage tube is connected and the connection outer sleeve outer connection portion; alkali metal storage tube portion connected to the injection needle is not placed in the injection control member.

[0012] 注射控制部件用于控制碱金属储存管内的碱金属流体向前流动,控制的方式可采用对碱金属储存管平压挤压、或者滚动挤压的方式。 [0012] control means for controlling the injection of alkali metal in the alkali metal reservoir fluid forward flow tube, in a controlled manner can be stored for an alkali metal tube platen pressing, extrusion or rolling manner.

[0013] 其中,所述注射控制部件包括螺栓、挤压物、载物台和螺栓固定台,所述载物台上设置挤压物,垂直或滚动挤压碱金属流体流动。 [0013] wherein, said injection control means includes a bolt, extrudates, and bolted stage table, the stage of the extrudate is provided, the vertical scroll or an alkali metal extruded fluid flow.

[0014] 作为本发明的优选技术方案之一,其中,所述注射控制部件包括螺栓、挤压物、螺栓固定台和载物台,载物台和螺栓固定台构成为有凹槽的结构,螺栓固定台位于凹槽结构的上方,凹槽内设置长方体形状的挤压物,挤压物顶面与螺栓的下端接触;所述螺栓固定台上设置有螺孔,所述螺栓通过螺孔与螺栓固定台连接。 [0014] As one preferred aspect of the present invention, wherein said injection control means includes a bolt, extrudates, bolt and the stage table, the stage table and bolted structure configured as a recess, bolt station is located above the groove structure is provided in the shape of a rectangular parallelepiped recess extrudate, the extrudate into contact with a top surface of the lower end of the bolt; and the fixing table is provided with a screw bolt, the bolt through holes and bolted connection table.

[0015] 碱金属储存管置于载物台和挤压物之间,挤压物随着螺栓的转动向下挤压碱金属储存管。 [0015] alkali metal between the storage stage and the tube is placed in the extrudate, the extrudate is pressed down with the rotation of the bolt alkali metal storage tube.

[0016] 作为本发明的另一优选技术方案,所述载物台上设置有放置碱金属储存管的凹槽,载物台上方设置有螺栓固定台,载物台和螺栓固定台之间放置圆柱状的挤压物。 [0016] As another preferred aspect of the present invention, there is provided on the stage placed in a recess of an alkali metal storage tube, the stage side fixing table is provided with a bolt, disposed between the stage and the stage bolts cylindrical extrudate. 载物台和螺栓固定台通过螺栓连接。 Stage and the stage is fixed by screwing bolts. 碱金属储存管置于载物台和挤压物之间,随着挤压物的滚动挤压碱金属储存管。 An alkali metal reservoir between the stage and the extruded tube was placed, with the rolling extrudate extruded alkali metal storage tube.

[0017] 优选地,所述载物台投影形状为长方形,长轴为放置碱金属储存管的凹槽的区域。 [0017] Preferably, the rectangular shape, the major axis of the groove area is placed in an alkali metal storage tube carrier stage projection shape.

[0018] 进一步地,所述一次性挤压式碱金属注射装置可以通过测量电阻变化来判断碱金属流体是否全部推出注射针。 [0018] Further, the disposable injection device squeeze alkali metal can be determined by measuring the change in resistance whether all of the alkali metal Release fluid injection needle. 所述一次性挤压式碱金属注射装置还包括电阻测量器件,所述电阻测量器件的一个测量端放置在注射针的斜口一端旁1_5mm距离内,另一个测量端与注射针的平口一端接触。 The squeeze type disposable injection device further comprises an alkali metal resistance measuring device, a measuring device measuring end of the resistor is placed within the range side 1_5mm beveled needle end, flat end of the other end of the measuring contact needle .

[0019] 作为本发明的再一个优选技术方案,所述一次性性挤压式碱金属注射装置可以利用电场推动碱金属流体流动,此时,在碱金属储存管中有一根导电丝,沿中轴线贯穿整个储存管,当注射针与碱金属储存管连接时,导电丝与不锈钢针管相连。 [0019] As the present invention is a further preferred aspect, the crush of the disposable injection device may utilize an alkali metal of alkali metal push fluid flow field, In this case, there is an alkali metal conductive yarn storage tube, along throughout the storage tube axis, when the needle tube is connected with an alkali metal reservoir, a conductive wire and a stainless steel tube connected to the needle. 碱金属储存管中导电丝接电压源负极,针电极接电压源正极,针电极和注射针插入组织中,且针电极放置在注射针的斜口一端旁l-5mm距离内,电压范围为2V-6V之间,在电场作用下,驱动碱金属流体从负极向正极一端移动。 Alkali metal storage tube of the conductive wire to the voltage source a negative needle electrode connected to a voltage source of the positive electrode, the needle electrode and the injection needle into the tissue, and the needle electrode is placed in a l-5mm range side beveled needle end, a voltage range of 2V between -6V, in the electric field, driving an alkali metal anode fluid moving from one end to the positive electrode.

[0020] 其中,所述碱金属流体为钠钾合金,所述钠钾合金中钠钾的质量比为1:0.8-9。 [0020] wherein the fluid is an alkali metal sodium potassium alloy, sodium-potassium alloy, the mass ratio of sodium and potassium is 1: 0.8-9. [0021]其中,所述保护液是具有生物相容性的为去除水分的有机溶剂,选自橄榄油、花生油、大豆油、菜籽油以及甘油中的一种或多种。 [0021] wherein the protective liquid is a biocompatible organic solvent for the removal of moisture, is selected from olive oil, one or more peanut oil, soybean oil, rapeseed oil and glycerol.

[0022]其中,在碱金属储存管中,所述保护液放置在碱金属流体两边。 [0022] wherein the alkali metal in the storage tube, the protection liquid on both sides of the fluid is placed in an alkali metal.

[0023] 其中,所述碱金属储存管为硅胶管,内径为0. :L-2. Oram。 [0023] wherein the alkali metal storage tube silicone tube, an inner diameter of 0.:. L-2 Oram.

[0024]其中,所述注射针有1-5根。 [0024] wherein the injection needle has 1-5 roots. 超过二根的注射针的设置,使用时,连接碱金属储存管的不锈钢钢管分别插入靶向组织中,与单点注射相比,增大了碱金属热疗的有效范围。 More than two injection needle is provided, in use, an alkali metal reservoir connected to stainless steel pipes are inserted into the targeted tissue as compared with a single point of injection, increasing the effective range of the alkali metal hyperthermia.

[0025](三)有益效果 [0025] (c) beneficial effect

[0026]本发明提出的一次性挤压式碱金属注射装置,在使用时碱金属不需要从储存容器中取出,而是直接将碱金属储存管连接注射针和注射装置后即可使用,减少了碱金属和空气接触的风险。 [0026] Disposable injection device of an alkali metal crush proposed by the invention, the alkali metal in use need not removed from the reservoir, but directly to the store to use an alkali metal pipe connecting the needle and the injection device to reduce alkali metal and risk of contact with air. 同时,钠钾合金密封在有保护液的碱金属储存管中,方便运输和储存。 Meanwhile, sodium-potassium alloy of an alkali metal storage tube sealed with a protective liquid, to facilitate transport and storage. 碱金属储存管为一次性用品,且每只碱金属储存管只装有微量的碱金属,避免了因长期储存大量碱金属而带来的安全隐患。 Alkali metal storage tube is one-time items, and each alkali metal storage tube containing only trace amounts of alkali metal, to avoid the long-term storage due to a large number of alkali metal and potential safety problems.

附图说明 BRIEF DESCRIPTION

[0027]图丨是碱金属储存管的结构示意图; [0027] FIG Shu is a schematic of an alkali metal storage tube;

[0028]图2是注射针结构示意图; [0028] FIG. 2 is a schematic view of the needle structure;

[0029] 图3⑸是采取平压方式的注射控制装置正视图; [0029] FIG 3⑸ injection control apparatus is to take a front view of platen embodiment;

[0030] 图3⑹是f取平压方式的注射控制装置侧视图; [0030] FIG 3⑹ f is a side view of the injection control device to take the pressure level of the embodiment;

[0031]图3 (c)_是采取平压方式的注射控制装置俯视图; [0031] FIG. 3 (c) _ take platen embodiment of a plan view of the injection control means;

[0032]图4是采取平压方式挤压碱金属储存管的操作示意图; [0032] FIG. 4 is a schematic view of the operation to take platen embodiment of an alkali metal storage tube extrusion;

[0033]图5 (a)是f取滚动挤压方式的注射控制装置结构正视图; [0033] FIG. 5 (a) is a control arrangement for injection f extruded rolling manner a front view;

[0034]图5⑹是采取滚动挤压方式的注射控制装置结构右视图; [0034] FIG 5⑹ way is to take a rolling pressing injection control arrangement a right side view;

[0035]图5 (c)是采取滚动挤压方式的注射控制装置结构仰视图; [0035] FIG. 5 (c) is a rolling take-injection control device configuration mode extruded bottom view;

[0036]图6是采取滚动挤压方式挤压碱金属储存管的操作示意图; [0036] FIG. 6 is a schematic view of the way to take a rolling pressing operation of pressing the alkali metal storage tube;

[0037]图7 (a)是利用电场推动碱金属流体的操作示意图; [0037] FIG. 7 (a) is a schematic view of the operation using an electric field of an alkali metal push fluid;

[0038]图7⑹是利用电场推动碱金属流体时碱金属储存管剖面图; [0038] FIG 7⑹ is an alkali metal using an electric field to promote alkali metal tube fluid storage sectional view when;

[0039]图8是多点注射碱金属热疗示意图。 [0039] FIG. 8 is a multi-point injection alkali metal hyperthermia FIG.

[0040]图中:1为碱金属储存管,2为碱金属流体,3为保护液,4为连接内套,5为不锈钢针管,6为连接外套,7为载物台,8为螺栓固定台,9为挤压物,10为螺栓,11为靶向组织,12为螺杆,13为螺母,14为通孔,15为针电极,16为导电丝,17为电压源。 [0040] FIG: 1 is an alkali metal storage tube, 2 is an alkali metal fluid, 3 is a protective solution, 4 connected to the inner sleeve, 5 a stainless steel needle tube 6 is connected to the jacket, 7 stage 8 is bolted Taiwan, was extruded 9, bolts 10, 11 to target tissue, a screw 12, a nut 13, a through hole 14, a needle electrode 15, electrically conductive wires 16, 17 to a voltage source.

具体实施方式 Detailed ways

[0041]下面结合附图和实施例,对本发明的具体实施方式作进一步详细描述。 [0041] The following embodiments and the accompanying drawings, specific embodiments of the present invention will be further described in detail. 以下实施例用于说明本发明,但不用来限制本发明的范围。 The following examples serve to illustrate the present invention but are not intended to limit the scope of the present invention.

[0042]实施例1采取平压方式挤压碱金属储存管 [0042] Example 1 taken by an alkali metal platen squeezing the storage pipe

[0043]本例的一次性挤压式碱金属注射装置,如图1、图2、图3所示,由碱金属储存管1、碱金属流体2、保护液3、注射针以及注射控制装置共同组成。 [0043] This embodiment of the disposable squeeze alkali metal injection apparatus, FIG. 1, FIG. 2, FIG. 3, an alkali metal storage tube 1, fluid 2 is an alkali metal, protection of liquid 3, an injection needle and an injection control means common components. 碱金属储存管1为具有一定弹性的桂胶管,管内依次装有保护液3、碱金属流体2和保护液3。 Alkali metal hose Gui storage tube 1 having a certain elasticity, the protection liquid sequentially with inner tube 3, an alkali metal, and protective solution 3 2 fluid. 碱金属流体2为钠钾质量比1:3 的钠钾合金,保护液3为去除水分的橄榄油。 2 is an alkali metal sodium, potassium, fluid mass ratio of 1: 3 sodium-potassium alloy, protective solution 3 to remove moisture olive oil. 使用前碱金属储存管1两端封闭,内直径为0.4mm。 Storage prior to use alkali metal tube 1 closed at both ends, an inner diameter of 0.4mm. 使用时一端与注射针连接。 One end connected to the injection needle during use. 碱金属储存管1 一端裹有连接内套4,连接内套4外壁有沟槽,用于连接注射针上的连接外套。 One end of an alkali metal reservoir connected to the inner pipe wrapped sleeve 4, inner sleeve 4 connected to an outer wall with a groove for connecting to the injection needle connector sleeve. 注射针包括不锈钢针管5和连接外套6,不锈钢针管5— 端是斜口,一端是平口,平头一端外侧有连接外套6,连接外套内侧有凸起。 The needle comprises a stainless steel needle tube 5 and connector sleeve 6, a stainless steel needle cannula is beveled end 5-, one end of a flat, blunt outer jacket 6 is connected at one end connected to the outer medial protrusions.

[0044] 注射针的控制采取平压的方式,注射控制装置包括载物台7、螺栓固定台8、挤压物9和螺栓10。 [0044] Control of the needle taken platen way, the injection control means comprises a stage 7, a bolt fixing table 8, 9 and the bolt 10 extrudate. 载物台7和螺栓固定台连接为有凹槽的结构(见图3(b),侧面投影形状为旋转90°的“凹”字),上部分为螺栓固定台8。 Stage fixing table 7 and the screw groove connection structure (see FIG. 3 (b), the side surface of the projected shape rotated by 90 ° "concave") to the upper part of a bolt fixing table 8. 螺栓10穿过螺栓固定台8,尾端与挤压物9接触,通过螺栓10的转动调整挤压物9和载物台7之间的距离。 8 through the bolt 10, in contact with the tail 9 was bolted pressing station, the distance between the object 9 and the stage 7 by turning the adjusting bolt 10 pressed in. 挤压物9为一立方体模块,挤压物9顶面与螺栓的下端接触;在与螺栓接触地方有一盲孔。 Extrudate is a cube modules 9, the lower end 9 a top surface of the extrudate in contact with the bolt; a blind hole in the contact place with the bolt. 挤压物底面与碱金属储存管1接触。 Extrudate contacts the bottom surface with an alkali metal storage tube 1.

[0045]如图4所示,使用时,首先连接注射针和碱金属储存管1,不锈钢针管5平口一端插入碱金属储存管1内。 [0045] As shown in FIG. 4, when used, is first connected to the injection needle and storage tube 1 is an alkali metal, stainless steel flat end of the needle tube 5 is inserted into an alkali metal storage tube 1. 然后将碱金属储存管1后端装有保护液3的部分放入注射控制装置载物台7和挤压物9之间并固定好,转动螺栓10,通过螺栓10的转动挤压碱金属储存管1从而推动管内碱金属流体2向针头流动。 Then a rear end of the tube contains an alkali metal protection liquid storage portion 3 into the injection control means and fixed between the loading station 7 and 9 extrudates, turn the bolt 10, pressed by the rotation of an alkali metal reservoir bolt 10 thus promoting the tube 1 tube 2 to the alkali metal needle fluid flow. 待不锈钢针管5斜口一端有保护液3流出时,将注射针插入组织中11,再继续转动螺栓10,直至将碱金属流体2完全推出针头进入靶向组织11内,完成碱金属热消融的过程。 Be stainless steel needle 5 mule when one end 3 effluent protection liquid, the injection needle is inserted into the tissue 11, then continued rotation of the bolt 10, until the alkali metal fluid 2 completely out of the needle into the targeted tissue 11, the completion of the alkali metal thermoablation process.

[0046]实施例2:采取滚动挤压方式挤压碱金属储存管 [0046] Example 2: taking an alkali metal rolling extrusion squeezing the storage pipe

[0047]本例的一次性挤压式碱金属注射装置,如图1、图2、图5所示,由碱金属储存管1、碱金属流体2、保护液3、注射针以及注射控制装置共同组成。 [0047] This embodiment of the disposable squeeze alkali metal injection apparatus, FIG. 1, FIG. 2, FIG. 5, an alkali metal storage tube 1, fluid 2 is an alkali metal, protection of liquid 3, an injection needle and an injection control means common components. 碱金属储存管1、碱金属流体2、保护液3的设置与实施例1相同。 An alkali metal storage tube 1, fluid 2 is an alkali metal, provided the protective solution 3 are the same as in Example 1.

[0048]注射针的控制采取滚动挤压的方式,注射控制装置包括载物台7、螺栓固定台8、挤压物9和螺栓10。 [0048] Control of the needle rolling take pressing manner, the injection control means comprises a stage 7, a bolt fixing table 8, 9 and the bolt 10 extrudate. 载物台7为一凹形台,沿中轴线有半圆柱面的凹槽,弧度与碱金属储存管丄吻合,深度等于碱金属储存管1半径长,作用是防止碱金属储存管1在滚动挤压过程中发生移动。 The stage 7 is a concave station, along the axis of the semicylindrical groove, arc tube with an alkali metal reservoir Shang anastomosis, a depth equal to a radius of an alkali metal storage tube length, is to prevent an alkali metal storage tube rolling moves during extrusion. 螺栓固定台8在载物台7两侧,每侧用两个固定的螺杆12与载物台7连接,并通过螺栓固定台8上方的螺母I3调整与载物台7之间的距离,螺栓固定台8上有等距的通孔14。 8 bolt fixing table 7 at both sides of the stage, each side with two fixing screw 12 is connected to the stage 7, and by a nut with the stage I3 adjusting bolt 8 over the distance between the fixing table 7, a bolt fixing table 8 equidistant through holes 14. 挤压物9为一滚轮,固定在载物台7中央,滚轮两端有侧臂,搭在载物台7和螺栓固定台8之间。 9 is a pressing roller was fixed to the center of the loading station 7, both ends of the rollers with a side arm, take between stage 7 and the bolt 8 fixed to the loading station.

[0049]如图6所示,首先连接注射针和碱金属储存管1,不锈钢针管5平口一端插入碱金属储存管1内。 [0049] As shown in FIG 6, first connect the injection needle 1 and an alkali metal storage tube, stainless steel flat end of the needle tube 5 is inserted into an alkali metal storage tube 1. 然后将碱金属储存管1后端装有保护液3的部分放入注射控制装置载物台7的凹槽中,转动螺杆12上的螺母13调整螺栓固定台8和载物台7之间的距离,使得挤压物9滚轮刚好能够转动。 Then an alkali metal storage tube 1 with the rear end portion of the protection liquid injection control apparatus 3 into the loading stage 7 in the groove, rotation of the nut screw 12 on the bolt 13 adjusts the fixing table 8 and the stage 7 between the distance, such that the pressing roller 9 was just rotatable. 使用时,推动滚轮两侧的侧臂,使得滚轮滚动挤压碱金属储存管1从而推动管内碱金属流体2向针头流动,需要固定滚轮位置时,用螺栓10穿过螺栓固定台上的通孔14, 转动螺栓压紧滚轮侧臂。 In use, the side arms push both sides of the roller, so that the pressing roller rolling an alkali metal storage tube 1 so as to promote the inner tube 2 to the alkali metal needle fluid flow necessary to fix the position of the wheel, the bolts passing through the through hole of the fixed table 10 by bolts 14, rotation of the bolt-side pinch roller arm. 待不锈钢针管5斜口一端有保护液3流出时,将注射针插入组织中11,再继续推动滚轮,直至将碱金属流体2完全推出针头进入靶向组织11内,完成碱金属热消融的过程。 To be a stainless steel needle tube 5 beveled end of a protective fluid 3 flows, the injection needle is inserted into the tissue 11, and then continue to drive the wheel, until the alkali metal fluid 2 completely out of the needle into the targeted tissue 11, to complete the process of the alkali metal thermoablation .

[0050] 本发明的注射装置还可以用电阻测量方式判断注射进程。 [0050] The injection device of the present invention may also be determined by resistance measurement injection procedure. 具体为将注射针和电阻测量仪的针电极插入靶向组织11,注射针尖端和针电极距离非常接近但不接触。 Specifically needle and the needle electrode resistance measuring instrument 11 is inserted into the targeted tissue, the needle tip and needle-electrode distance is very close but not touching. 测量不锈钢针管5平口一端到针电极之间的电阻变化,判断注射的进程。 Measuring flat stainless steel needle tube 5 to the end of change in resistance between the electrode needle, the injection process is determined.

[0051] 实施例3 [0051] Example 3

[0052] 本注射装置,还可以利用电场推动碱金属流体2流动,如图7 (a)和⑹所示,此时, 在碱金属储存管1中有一根导电丝16,沿中轴线贯穿整个碱金属储存管1,当注射针与碱金属储存管1连接时,导电丝16与不锈钢针管5相连。 [0052] The present injection apparatus, an electric field can also be used to promote the flow of fluid an alkali metal 2, FIG. 7 (a) and FIG ⑹, at this time, there is an electrically conductive wire 16 in an alkali metal storage tube 1, along the axis throughout an alkali metal storage tube 1, when the injection needle with an alkali metal reservoir connected to the tube 1, is connected to the conductive wire 16 and stainless steel needle tube 5. 使用时,碱金属储存管1中导电丝16接6V 的电压源17负极,针电极15接电压源17正极。 When used, the alkali metal in a conductive yarn storage tube 16 connected to a negative voltage source 17 is 6V, the needle electrode 15 is connected to a positive voltage source 17. 将针电极15和不锈钢针管5插入组织中,针电极15放置在不锈钢针管5的斜口一端旁l_5mm距离内,碱金属流体2在电场驱动作用下从负极向正极一端移动。 The needle electrode 15 and the stainless steel needle tube 5 is inserted into the tissue, the needle electrode 15 is placed in a stainless steel l_5mm range side beveled end of the needle tube 5, the alkali metal anode fluid 2 moves from the one end to the positive electrode in the electric field driving action.

[0053] 实施例4:多点注射碱金属热疗 [0053] Example 4: Multi-point injection alkali metal hyperthermia

[0054] 在这一实施例中,挤压方式、注射控制装置和实施例一相同。 [0054] In this embodiment, the pressing mode, the injection control means and a same embodiment. 如图8所示,使用时, 连接碱金属储存管的不锈钢钢管5有3个,分别插入靶向组织中,与单点注射相比,增大了碱金属热疗的有效范围。 As shown, in use, an alkali metal reservoir connected to stainless steel tube with a 3 5 8, are inserted into the targeted tissue as compared with a single point of injection, increasing the effective range of the alkali metal hyperthermia.

[0055] 综上所述,本发明提供了一种操作简单、安全的一次性挤压式室温液态碱金属注射装置。 [0055] In summary, the present invention provides a simple, safe disposable squeeze liquid alkali metal temperature of the injection device. 本发明使得碱金属热疗在实施时直接将装有碱金属的碱金属储存管和注射针、注射控制装置连接以后即可使用,操作简单可靠,而且碱金属储存管在运输和使用过程中都具有非常好的安全性0 The present invention is such that the alkali metal base hyperthermia directly with the alkali metal in the practice of storage tubes and a metal injection needle, can be used after an injection control device is connected, simple and reliable operation, and an alkali metal storage tube in both transport and use It has a very good safety 0

[0056] 最后应说明的是,以上实施例仅用以说明本发明的技术方案而非限制,尽管参照较佳实施例对本发明进行了详细说明,本领域技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本发明技术方案的精神和范围,其均应当涵盖在本发明的权利要求范围当中。 [0056] Finally, it should be noted that the above embodiments are intended to illustrate and not limit the present invention, although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should appreciate that the techniques of the present invention program modifications or equivalent replacements without departing from the spirit and scope of the technical solutions of the present invention, each of which should cover the claimed invention in which the required range.

Claims (9)

1.一种一次性挤压式碱金属注射装置,其特征在于,包括碱金属储存管、碱金属流体、 保护液、注射针以及注射控制部件; 使用前碱金属储存管两端封闭,碱金属流体和保护液放置在碱金属储存管中;使用时一端与注射针连接; 所述注射针的一端为斜口,另一端为平口,平口的一端外设置有连接外套,所述注射针与碱金属储存管的一端连接且连接外套套在连接部位外;碱金属储存管没有连接注射针的部分放置在注射控制部件中。 1. A disposable squeeze alkali metal injection apparatus, wherein the storage tube comprising an alkali metal, an alkali metal fluids, protection liquid, an injection needle and an injection control means; storage pipe ends prior to use alkali metal closure, an alkali metal fluid and protection was placed in an alkali metal storage pipe; one end connected to the injection needle use; end of the needle is beveled, and the other end is flat, the outer end flat is provided with a connector sleeve, the injection needle with a base end of the metal tube is connected to and stored in the external connecting portion connected to the outer sleeve; an alkali metal storage tube portion is not connected to the injection needle is placed in the control member.
2.根据权利要求1所述的注射装置,其特征在于所述注射控制部件包括螺栓、挤压物、 载物台和螺栓固定台,所述载物台上设置挤压物,所述挤压物挤压碱金属储存管的方式为平压或滚动挤压。 2. The injection device according to claim 1, wherein said injection control means includes a bolt, extrudates, and bolted stage table, the stage of the extrudate is provided, the pressing extruding an alkali metal storage tube way for pressing or rolling platen.
3. 根据权利要求1或2任一项所述的注射装置,其特征在于,所述注射控制部件包括螺栓、挤压物、螺栓固定台和载物台,载物台和螺栓固定台构成为有凹槽的结构,螺栓固定台位于凹槽结构的上方,凹槽内设置长方体形状的挤压物,挤压物顶面与螺栓的下端接触;所述螺栓固定台上设置有螺孔,所述螺栓通过螺孔与螺栓固定台连接。 The injection device according to any of claims 1 and 2, wherein said injection control means includes a bolt, extrudates, bolt fixing table and the stage, the stage and the stage is configured to be bolted a groove structure, is located above the fixing table bolt groove structure is provided in the shape of rectangular parallelepiped recess extrudate, the top surface of the lower end of the bolt extrudate; contacting the fixing table is provided with a screw bolt, the said screw bolt via a bolt fixing table.
4. 根据权利要求1或2所述的注射装置,其特征在于,所述注射控制部件包括螺栓、挤压物和载物台,所述载物台上设置有放置碱金属储存管的凹槽,载物台上方设置有螺栓固定台,载物台和螺栓固定台之间放置圆柱状的挤压物;载物台和螺栓固定台通过螺栓连接。 An injection device according to claim 1 or claim 2, wherein said injection control means includes a bolt, extrudates and the stage, the stage is provided with a recess placed in an alkali metal storage tube , the stage side fixing table is provided with a bolt, the cylindrical extrudate is placed between the stage and the bolt fixing table; stage station and bolts bolted.
5. 根据权利要求1所述的注射装置,其特征在于,所述注射控制部件包括2-6V电压源, 电压源连接有正极和负极,所述正极和负极为金属丝,正极插入碱金属储存管中。 The injection device according to claim 1, wherein said injection control means includes 2-6V voltage source, a voltage source connected to positive and negative electrodes, the positive electrode and the negative electrode is a wire, is inserted into the positive electrode alkali metal reservoir tube.
6.根据权利要求1所述的注射装置,其特征在于,其特征在于,所述碱金属流体为钠钾合金;所述钠钾合金中钠钾的质量比为1:3。 6. The injection device according to claim 1, wherein, wherein the alkali metal is sodium potassium alloy fluid; a sodium-potassium alloy, sodium and potassium in the mass ratio of 1: 3.
7. 根据权利要求1所述的注射装置,其特征在于,所述保护液是具有生物相容性的为去除水分的有机溶剂,选自橄榄油、花生油、大豆油、菜籽油以及甘油中的一种或多种。 7. The injection device according to claim 1, wherein said protective liquid is a biocompatible organic solvent for the removal of moisture, is selected from olive oil, peanut oil, soybean oil, rapeseed oil and glycerin one or more.
8. 根据权利要求1-2和权利要求5-7任一项所述的注射装置,其特征在于,所述碱金属储存管为硅胶管,内径为0.1-2. Omm;在碱金属储存管中,所述保护液放置在碱金属流体两边。 An injection device according to claim any one of claims 5-71-2 and claims, characterized in that the alkali metal storage tube silicone tube, an inner diameter of 0.1-2 Omm;. An alkali metal storage pipe , the alkali metal protection liquid is placed on both sides of the fluid.
9. 根据权利要求1-2和权利要求5-7任一项所述的注射装置,其特征在于,所述注射针有1-5根。 9. An injection device according to any one of 5-71-2 and claims, characterized in that said injection needle has the root according to claim 1-5.
CN201410818356.6A 2014-12-24 2014-12-24 Disposable injection device of extruded alkali metal CN105769329B (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525164A (en) * 1981-04-24 1985-06-25 Biotek, Inc. Wearable medication infusion system with arcuated reservoir
US5549569A (en) * 1994-02-15 1996-08-27 Lawrence A. Lynn Ex vivo blood isolation system
CN2366119Y (en) * 1999-04-28 2000-03-01 杨忠 Electrically driven infusion device
CN202314718U (en) * 2011-11-17 2012-07-11 山东大学 Flexible microinjector
CN202802347U (en) * 2012-10-24 2013-03-20 王双燕 Zero gravity infusion apparatus
CN203043144U (en) * 2013-01-12 2013-07-10 张艳 Rapid blood transfusion pressurizing device for puerperae
CN203169735U (en) * 2013-04-29 2013-09-04 德州市第二中学 Extruding intravenous injector
CN203183417U (en) * 2013-04-10 2013-09-11 杨力 Zero-gravity infusion apparatus

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525164A (en) * 1981-04-24 1985-06-25 Biotek, Inc. Wearable medication infusion system with arcuated reservoir
US5549569A (en) * 1994-02-15 1996-08-27 Lawrence A. Lynn Ex vivo blood isolation system
CN2366119Y (en) * 1999-04-28 2000-03-01 杨忠 Electrically driven infusion device
CN202314718U (en) * 2011-11-17 2012-07-11 山东大学 Flexible microinjector
CN202802347U (en) * 2012-10-24 2013-03-20 王双燕 Zero gravity infusion apparatus
CN203043144U (en) * 2013-01-12 2013-07-10 张艳 Rapid blood transfusion pressurizing device for puerperae
CN203183417U (en) * 2013-04-10 2013-09-11 杨力 Zero-gravity infusion apparatus
CN203169735U (en) * 2013-04-29 2013-09-04 德州市第二中学 Extruding intravenous injector

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