CN105769329A - Disposable extrusion-type alkali metal injection device - Google Patents
Disposable extrusion-type alkali metal injection device Download PDFInfo
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- CN105769329A CN105769329A CN201410818356.6A CN201410818356A CN105769329A CN 105769329 A CN105769329 A CN 105769329A CN 201410818356 A CN201410818356 A CN 201410818356A CN 105769329 A CN105769329 A CN 105769329A
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- alkali metal
- memotron
- injection device
- injection
- extrudate
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Abstract
The invention relates to a disposable extrusion-type alkali metal injection device. The disposable extrusion-type alkali metal injection device comprises an alkali metal storage pipe, alkali metal fluid, protection fluid, an injection needle and an injection control part, wherein one end of the injection needle is provided with a bevel opening, the other end of the injection needle is provided with a flat opening, a connecting sleeve is arranged outside the end with the flat opening, the injection needle is connected with one end of the alkali metal storage pipe, and the connecting sleeve sleeves the connecting part; the other end of the alkali metal storage pipe is connected with the injection control part; and the alkali metal fluid and the protection fluid are placed in the alkali metal storage pipe. When the disposable extrusion-type alkali metal injection device is used, alkali metal does not need to be taken out from the storage container, but can be directly used after the alkali metal storage pipe is connected with the injection needle and an injection device, therefore, the risk that the alkali metal contacts air is reduced, and the transportation and storage are also convenient; the alkali metal storage pipe is a disposable product, and each alkali metal storage pipe is only filled with trace amount of alkali metal, therefore, the potential safety hazards caused by storage of large amount of alkali metal for a long time are avoided.
Description
Technical field
The invention belongs to medical instruments field, be specifically related to a kind of medium introduce with injection system internal apparatus.
Background technology
It is an important channel of tumor physical therapy that high-temperature hot melts, but includes radio frequency, microwave, laser, ultrasonic traditional heating pattern and tissue on the way can cause when energy is transported to deep tumor scald and many equipment complex and expensive.Alkali metal heating therapy breaks through tradition thermotherapy technical concept, by water environment naturally occurring in destination organization, produces strong heat-producing chemical reaction by injecting the sodium of trace, potassium or its alloy fluid, thus reaching efficient heating ablation purpose.
But, just because of alkali-metal above-mentioned characteristic, also make alkali metal thermotherapy there is certain safety risks, Na-K alloy must be avoided in actual applications to contact with air or water.Na-K alloy is at room temperature liquid, it is possible to is expelled to target area with syringe, but is required for first absorption alkali metal fluid when ordinary syringe uses, and poor sealing, this adds the risk of alkali metal and air contact undoubtedly.It addition, alkali metal be expelled to internal before had always a demand for protection liquid isolation air, have only to the alkali metal of trace in actual applications every time simultaneously, these are all that ordinary syringe institute is unappeasable.
Summary of the invention
(1) to solve the technical problem that
It is an object of the invention to the problem existing for alkali metal technique for hyperthermia, it is provided that a kind of simple to operate, safe disposable squash type room temperature liquid alkali metal injection device.
(2) technical scheme
The purpose of the present invention is achieved through the following technical solutions:
A kind of disposable squash type alkali metal injection device, including alkali metal memotron, alkali metal
Fluid, protection liquid, entry needle and injection control parts；
Front alkali metal memotron closed at both ends, alkali metal fluid and protection liquid is used to be placed in alkali metal memotron；During use, one end is connected with entry needle；
One end of described entry needle is angle, and the other end is flat mouth, and one end of flat mouth is outside equipped with connection overcoat, and described entry needle is connected and connects overcoat with one end of alkali metal memotron and is enclosed within outside connecting portion；Alkali metal memotron does not connect the injection that is partially disposed in of entry needle and controls in parts.
Injection controls the parts alkali metal forward fluid motion for controlling in alkali metal memotron, and the mode of control can adopt the mode to the extruding of alkali metal memotron concora crush or rolling extrusion.
Wherein, described injection controls parts and includes bolt, extrudate, object stage and bolt fixed station, and described object stage arranges extrudate, vertical or rolling extrusion alkali metal fluid flowing.
As one of the preferred technical solution of the present invention, wherein, described injection controls parts and includes bolt, extrudate, bolt fixed station and object stage, object stage and bolt fixed station are configured to reeded structure, bolt fixed station is positioned at the top of groove structure, the lower end in contact of the extrudate of rectangular shape, extrudate end face and bolt is set in groove；Being provided with screw on described bolt fixed station, described bolt is connected with bolt fixed station by screw.
Alkali metal memotron is placed between object stage and extrudate, and extrudate is pressed down against alkali metal memotron along with the rotation of bolt.
As another optimal technical scheme of the present invention, described object stage being provided with the groove placing alkali metal memotron, object stage is provided above bolt fixed station, places columned extrudate between object stage and bolt fixed station.Object stage and bolt fixed station are bolted.Alkali metal memotron is placed between object stage and extrudate, along with the rolling extrusion alkali metal memotron of extrudate.
Preferably, described object stage projection of shape is rectangle, and major axis is the region of the groove placing alkali metal memotron.
Further, by measurement resistance variations, described disposable squash type alkali metal injection device can judge whether alkali metal fluid all releases entry needle.Described disposable squash type alkali metal injection device also includes resistance measurement device, and of described resistance measurement device measures end and is placed in the other 1-5mm distance in angle one end of entry needle, and another measures the flat mouth end thereof contacts of end and entry needle.
Another optimal technical scheme as the present invention, described disposable property squash type alkali metal injection device can utilize electric field to promote the flowing of alkali metal fluid, now, alkali metal memotron has a conductive filament, whole memotron is run through along axis, when entry needle is connected with alkali metal memotron, conductive filament is connected with rustless steel needle tubing.Conduction wire connection voltage source negative pole in alkali metal memotron, needle electrode connects voltage source positive pole, needle electrode and entry needle insert in tissue, and needle electrode is placed in the other 1-5mm distance in angle one end of entry needle, voltage range is between 2V-6V, under electric field action, alkali metal fluid is driven to move from negative pole to positive pole one end.
Wherein, described alkali metal fluid is Na-K alloy, and in described Na-K alloy, the mass ratio of sodium potassium is 1:0.8-9.
Wherein, described protection liquid is the organic solvent for removing moisture with biocompatibility, one or more in olive oil, Oleum Arachidis hypogaeae semen, soybean oil, Oleum Brassicae campestris and glycerol.
Wherein, in alkali metal memotron, described protection liquid is placed on alkali metal fluid both sides.
Wherein, described alkali metal memotron is silica gel tube, and internal diameter is 0.1-2.0mm.
Wherein, described entry needle has 1-5 root.The setting of the entry needle more than two, during use, the stainless-steel pipe connecting alkali metal memotron inserts in target tissue respectively, compared with injecting with single-point, increases the effective range of alkali metal thermotherapy.
(3) beneficial effect
The disposable squash type alkali metal injection device that the present invention proposes, alkali metal from storing taking-up container, but can need not use after directly alkali metal memotron being connected entry needle and injection device in use, decreases the risk of alkali metal and air contact.Meanwhile, Na-K alloy is sealed in the alkali metal memotron of protection liquid, conveniently transport and storage.Alkali metal memotron is disposable product, and every alkali metal memotron is only equipped with the alkali metal of trace, it is to avoid the potential safety hazard brought because of a large amount of alkali metal of long term storage.
Accompanying drawing explanation
Fig. 1 is the structural representation of alkali metal memotron；
Fig. 2 is entry needle structural representation；
Fig. 3 (a) is the injection control apparatus front view taking concora crush mode；
Fig. 3 (b) is the injection control apparatus side view taking concora crush mode；
Fig. 3 (c) is the injection control apparatus top view taking concora crush mode；
Fig. 4 is the operation chart taking concora crush mode to extrude alkali metal memotron；
Fig. 5 (a) is the injection control apparatus structure front view taking rolling extrusion mode；
Fig. 5 (b) is the injection control apparatus structure right view taking rolling extrusion mode；
Fig. 5 (c) is the injection control apparatus structure upward view taking rolling extrusion mode；
Fig. 6 is the operation chart taking rolling extrusion mode to extrude alkali metal memotron；
Fig. 7 (a) is the operation chart utilizing electric field to promote alkali metal fluid；
Alkali metal memotron profile when Fig. 7 (b) is to utilize electric field promotion alkali metal fluid；
Fig. 8 is multi-point injection alkali metal thermotherapy schematic diagram.
In figure: 1 is alkali metal memotron, 2 is alkali metal fluid, and 3 is protection liquid; 4 for connecting inner sleeve, and 5 is rustless steel needle tubing, and 6 for connecting overcoat; 7 is object stage, and 8 is bolt fixed station, and 9 is extrudate; 10 is bolt, and 11 is target tissue, and 12 is screw rod; 13 is nut, and 14 is through hole, and 15 is needle electrode; 16 is conductive filament, and 17 is voltage source.
Detailed description of the invention
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following example are used for illustrating the present invention, but are not limited to the scope of the present invention.
Embodiment 1 takes concora crush mode to extrude alkali metal memotron
The disposable squash type alkali metal injection device of this example, as shown in Figure 1, Figure 2, Figure 3 shows, is collectively constituted by alkali metal memotron 1, alkali metal fluid 2, protection liquid 3, entry needle and injection control apparatus.Alkali metal memotron 1, for having certain elastic silica gel tube, is sequentially arranged with protection liquid 3, alkali metal fluid 2 and protection liquid 3 in pipe.Alkali metal fluid 2 is the Na-K alloy of sodium potassium mass ratio 1:3, and protection liquid 3 is the olive oil removing moisture.Using front alkali metal memotron 1 closed at both ends, interior diameter is 0.4mm.During use, one end is connected with entry needle.Alkali metal memotron 1 one end is wrapped with connection inner sleeve 4, and connecting inner sleeve 4 outer wall has groove, for connecting the connection overcoat on entry needle.Entry needle includes rustless steel needle tubing 5 and connects overcoat 6, and rustless steel needle tubing 5 one end is angle, and one end is flat mouth, has connection overcoat 6 outside tack one end, connects and has projection inside overcoat.
The mode of concora crush is taked in the control of entry needle, and injection control apparatus includes object stage 7, bolt fixed station 8, extrudate 9 and bolt 10.Object stage 7 and bolt fixed station are connected as reeded structure (see Fig. 3 (b), side projection is shaped as " recessed " word of half-twist), and top is divided into bolt fixed station 8.Bolt 10 is through bolt fixed station 8, and tail end contacts with extrudate 9, by the distance rotated between adjustment extrudate 9 and object stage 7 of bolt 10.Extrudate 9 is a cube module, the lower end in contact of extrudate 9 end face and bolt；A blind hole is being had with threaded bolt contacts place.Extrudate bottom surface contacts with alkali metal memotron 1.
As shown in Figure 4, during use, first connecting entry needle and alkali metal memotron 1, rustless steel needle tubing 5 flat mouth one end is inserted in alkali metal memotron 1.Then by alkali metal memotron 1 rear end being partially placed between injection control apparatus object stage 7 and extrudate 9 and fixing equipped with protection liquid 3; rotating bolt 10, extrudes alkali metal memotron 1 by the rotation of bolt 10 thus promoting alkali metal fluid 2 in pipe to flow to syringe needle.When rustless steel needle tubing 5 angle one end has protection liquid 3 to flow out, by entry needle insertion tissue 11, being further continued for rotating bolt 10, until being entered in target tissue 11 by completely out for alkali metal fluid 2 syringe needle, completing the process of alkali metal heating ablation.
Embodiment 2: take rolling extrusion mode to extrude alkali metal memotron
The disposable squash type alkali metal injection device of this example, as shown in Figure 1, Figure 2, Figure 5, is collectively constituted by alkali metal memotron 1, alkali metal fluid 2, protection liquid 3, entry needle and injection control apparatus.Alkali metal memotron 1, alkali metal fluid 2, protection liquid 3 setting and embodiment 1 identical.
The mode of rolling extrusion is taked in the control of entry needle, and injection control apparatus includes object stage 7, bolt fixed station 8, extrudate 9 and bolt 10.Object stage 7 is a spill platform, has the groove of semi-cylindrical along axis, and radian coincide with alkali metal memotron 1, and the degree of depth is equal to alkali metal memotron 1 half path length, and effect is to prevent alkali metal memotron 1 to be moved in rolling extrusion process.Bolt fixed station 8 is in object stage 7 both sides, and every side is connected with object stage 7 with two fixing screw rods 12, and is bolted the nut 13 above platform 8 and adjusts the distance between object stage 7, and bolt fixed station 8 has equidistant through hole 14.Extrudate 9 is a roller, is fixed on object stage 7 central authorities, and there is side arm at roller two ends, ride between object stage 7 and bolt fixed station 8.
As shown in Figure 6, first connecting entry needle and alkali metal memotron 1, rustless steel needle tubing 5 flat mouth one end is inserted in alkali metal memotron 1.Then by alkali metal memotron 1 rear end equipped with in the groove being partially placed into injection control apparatus object stage 7 protecting liquid 3, the nut 13 rotated on screw rod 12 adjusts the distance between bolt fixed station 8 and object stage 7 so that extrudate 9 roller just can rotate.During use, the side arm of pushing rolling wheels both sides so that roller rolling extrusion alkali metal memotron 1 is thus promoting alkali metal fluid 2 in pipe to flow to syringe needle, it is necessary to during fixed idler whell position, with the through hole 14 on bolt 10 traverse bolt fixed station, rotating bolt pinch rollers side arm.When rustless steel needle tubing 5 angle one end has protection liquid 3 to flow out, by entry needle insertion tissue 11, being further continued for pushing rolling wheels, until being entered in target tissue 11 by completely out for alkali metal fluid 2 syringe needle, completing the process of alkali metal heating ablation.
The injection device of the present invention can also use resistance metering system to judge injection process.Being specially and the needle electrode of entry needle and resistance measuring instrument is inserted target tissue 11, entry needle is most advanced and sophisticated closely but not to be contacted with needle electrode distance.Measure rustless steel needle tubing 5 flat mouth one end to the resistance variations between needle electrode, it is judged that the process of injection.
Embodiment 3
This injection device, electric field can also be utilized to promote alkali metal fluid 2 to flow, as shown in Fig. 7 (a) and (b), now, alkali metal memotron 1 has a conductive filament 16, run through whole alkali metal memotron 1 along axis, when entry needle is connected with alkali metal memotron 1, conductive filament 16 is connected with rustless steel needle tubing 5.During use, in alkali metal memotron 1, conductive filament 16 connects voltage source 17 negative pole of 6V, and needle electrode 15 connects voltage source 17 positive pole.Inserting in tissue by needle electrode 15 and rustless steel needle tubing 5, needle electrode 15 is placed in the other 1-5mm distance in angle one end of rustless steel needle tubing 5, and alkali metal fluid 2 moves from negative pole to positive pole one end under electric field driven effect.
Embodiment 4: multi-point injection alkali metal thermotherapy
In this embodiment, fashion of extrusion, injection control apparatus are identical with embodiment one.As shown in Figure 8, during use, the stainless-steel pipe 5 connecting alkali metal memotron has 3, inserts in target tissue respectively, compared with injecting with single-point, increases the effective range of alkali metal thermotherapy.
In sum, the invention provides a kind of simple to operate, safe disposable squash type room temperature liquid alkali metal injection device.The invention enables alkali metal thermotherapy directly to will be equipped with alkali-metal alkali metal memotron when implementing and entry needle, injection control apparatus can use after connecting, operation is simple and reliable, and alkali metal memotron all has extraordinary safety in transport and use procedure.
Finally it should be noted that, above example is only in order to illustrate technical scheme and unrestricted, although the present invention being described in detail with reference to preferred embodiment, skilled artisan would appreciate that, technical scheme can be modified or equivalent replacement, without deviating from the spirit and scope of technical solution of the present invention, it all should be encompassed in the middle of scope of the presently claimed invention.
Claims (10)
1. a disposable squash type alkali metal injection device, it is characterised in that include alkali metal memotron, alkali metal fluid, protection liquid, entry needle and injection and control parts；
Front alkali metal memotron closed at both ends, alkali metal fluid and protection liquid is used to be placed in alkali metal memotron；During use, one end is connected with entry needle；
One end of described entry needle is angle, and the other end is flat mouth, and one end of flat mouth is outside equipped with connection overcoat, and described entry needle is connected and connects overcoat with one end of alkali metal memotron and is enclosed within outside connecting portion；Alkali metal memotron does not connect the injection that is partially disposed in of entry needle and controls in parts.
2. injection device according to claim 1, it is characterised in that the mode of described extrudate extruding alkali metal memotron is concora crush or rolling extrusion.
3. injection device according to claim 1, it is characterised in that described injection controls parts and includes bolt, extrudate, object stage and bolt fixed station, and described object stage arranges extrudate.
4. the injection device according to any one of claim 1-3, it is characterized in that, described injection controls parts and includes bolt, extrudate, bolt fixed station and object stage, object stage and bolt fixed station are configured to reeded structure, bolt fixed station is positioned at the top of groove structure, the lower end in contact of the extrudate of rectangular shape, extrudate end face and bolt is set in groove；Being provided with screw on described bolt fixed station, described bolt is connected with bolt fixed station by screw.
5. according to the arbitrary described injection device of claim 1-3, it is characterized in that, described injection controls parts and includes bolt, extrudate and object stage, described object stage is provided with the groove placing alkali metal memotron, object stage is provided above bolt fixed station, places columned extrudate between object stage and bolt fixed station；Object stage and bolt fixed station are bolted.
6. injection device according to claim 1, it is characterised in that described injection controls parts and includes 2-6.V voltage source, and it is tinsel that voltage source is connected to positive pole and negative pole, described positive pole and negative pole, and positive pole inserts in alkali metal memotron.
7. injection device according to claim 1, it is characterised in that it is characterized in that, described alkali metal fluid is Na-K alloy；In described Na-K alloy, the mass ratio of sodium potassium is 1:0.8-9.
8. injection device according to claim 1, it is characterised in that described protection liquid is the organic solvent for removing moisture with biocompatibility, one or more in olive oil, Oleum Arachidis hypogaeae semen, soybean oil, Oleum Brassicae campestris and glycerol.
9. the injection device according to claim 1-3 and any one of claim 6-8, it is characterised in that described alkali metal memotron is silica gel tube, and internal diameter is 0.1-2.0mm；In alkali metal memotron, described protection liquid is placed on alkali metal fluid both sides.
10. the injection device according to claim 1-3 and any one of claim 6-8, it is characterised in that described entry needle has 1-5 root.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410818356.6A CN105769329B (en) | 2014-12-24 | 2014-12-24 | Disposable squash type alkali metal injection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410818356.6A CN105769329B (en) | 2014-12-24 | 2014-12-24 | Disposable squash type alkali metal injection device |
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| Publication Number | Publication Date |
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| CN105769329A true CN105769329A (en) | 2016-07-20 |
| CN105769329B CN105769329B (en) | 2018-02-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410818356.6A Active CN105769329B (en) | 2014-12-24 | 2014-12-24 | Disposable squash type alkali metal injection device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107007834A (en) * | 2017-05-10 | 2017-08-04 | 苏州万化集成生物科技有限公司 | Tumor thermotherapy pill and its preparation facilities, preparation technology |
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| CN202314718U (en) * | 2011-11-17 | 2012-07-11 | 山东大学 | Flexible microinjector |
| CN202802347U (en) * | 2012-10-24 | 2013-03-20 | 王双燕 | Zero gravity infusion apparatus |
| CN203043144U (en) * | 2013-01-12 | 2013-07-10 | 张艳 | Rapid blood transfusion pressurizing device for puerperae |
| CN203169735U (en) * | 2013-04-29 | 2013-09-04 | 德州市第二中学 | Extruding intravenous injector |
| CN203183417U (en) * | 2013-04-10 | 2013-09-11 | 杨力 | Zero-gravity infusion apparatus |
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Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4525164A (en) * | 1981-04-24 | 1985-06-25 | Biotek, Inc. | Wearable medication infusion system with arcuated reservoir |
| US5549569A (en) * | 1994-02-15 | 1996-08-27 | Lawrence A. Lynn | Ex vivo blood isolation system |
| CN2366119Y (en) * | 1999-04-28 | 2000-03-01 | 杨忠 | Electrically driven infusion device |
| CN202314718U (en) * | 2011-11-17 | 2012-07-11 | 山东大学 | Flexible microinjector |
| CN202802347U (en) * | 2012-10-24 | 2013-03-20 | 王双燕 | Zero gravity infusion apparatus |
| CN203043144U (en) * | 2013-01-12 | 2013-07-10 | 张艳 | Rapid blood transfusion pressurizing device for puerperae |
| CN203183417U (en) * | 2013-04-10 | 2013-09-11 | 杨力 | Zero-gravity infusion apparatus |
| CN203169735U (en) * | 2013-04-29 | 2013-09-04 | 德州市第二中学 | Extruding intravenous injector |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107007834A (en) * | 2017-05-10 | 2017-08-04 | 苏州万化集成生物科技有限公司 | Tumor thermotherapy pill and its preparation facilities, preparation technology |
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| CN105769329B (en) | 2018-02-23 |
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