CN105769165A - Biological-body-surface weak-electric-signal collecting and exciting control system - Google Patents
Biological-body-surface weak-electric-signal collecting and exciting control system Download PDFInfo
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- CN105769165A CN105769165A CN201610153586.4A CN201610153586A CN105769165A CN 105769165 A CN105769165 A CN 105769165A CN 201610153586 A CN201610153586 A CN 201610153586A CN 105769165 A CN105769165 A CN 105769165A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
Abstract
The invention discloses a biological-body-surface weak-electric-signal collecting and exciting control system.A flexible PCB is used as an electrode detecting array of a substrate at a front end, and the front end is connected with a controllable channel selector through a shielding cable, and is further connected with a single-chip microcomputer control system.A signal control end comprises a signal front-end input photocoupling amplifying module, a low-pass filtering module, a single-chip microcomputer control module, an output amplifying module, an externally-connected storage module and an input keyboard, and the single-chip microcomputer control module is connected with the storage module through a serial port.As electrode array points are scanned, controlling over the states of all the electrode points is achieved, and therefore efficient measuring of the electrode array is achieved.
Description
Technical field
The present invention relates to a kind of organism surface ultra-weak electronic signal that is applicable to gather and excitation control system, particularly relate to the electrod-array detection method of a kind of bio signal transmission characteristic.
Background technology
One of signal of telecommunication detection difficult problem being always up biomedical sector of organism surface.The signal of telecommunication detection of organism surface has problems with:
1, signal amplitude is very faint, such as neuropotential, electromyographic signal etc., cannot directly obtain with conventional detection method and equipment, if introducing amplifier, then can bring very big interference and original signal characteristic is flooded by noise signal.
2, the acquisition major part of existing bioelectrical signals adopts microelectrode, and in order to obtain the small-signal such as electroneurographic signal, biological triggering signal, in order to avoid noise, adopt intrusive mood detection method (such as needle electrode etc.), not only tested organism is brought extra injury, and new noise can be introduced.
3, bio signal is non-stationary signal, and randomness is strong, needs to change in time according to different test conditions and demand, the state of electrode and detection method.
4, because the characteristic of organism and bio signal itself, existing detection electrode cannot ensure the concordance of test condition.
For the problems referred to above, the present invention proposes a kind of collection for organism surface ultra-weak electronic signal and excitation control system.
Summary of the invention
The technical problem to be solved is to provide a kind of electrode detector system efficient, reliable for organism body surface ultra-weak electronic signal, with realize the signal of telecommunication stable, efficiently detect.
For solving above-mentioned technical problem, the present invention by the following technical solutions:
A kind of detection electrode of organism body surface signal, it includes flexible printed circuit board carrier, carrier is provided with the electrode arrangement point position of array-like, each some position arranges pad, and on circuit boards by the mode of printed wiring, each electrode points position pad being electrically connected to common interface end, common interface end can detection/excitation and level to sensing point electrode be controlled as required.On electrode points position, realized the electrical connection of scolding tin and pad by the mode of scolding tin filling pad.Scolding tin packed height should be uniformly controlled at 2mm, is shaped as hemispherical, plated surface silver chloride, avoids oxidized to adapt to the environment of repetitive measurement.
This matching used detection system of detection electrode, its designing points is as follows: adopt low frequency shielded cable to make connecting line component, it is to avoid the interfering with each other and introduce noise of ultra-weak electronic signal.Its wiring includes the data connecting line of each electrode points, ground signalling transmission special circuit.Data connecting line and ground signal line are staggered the crosstalk reducing between holding wire to greatest extent.Output port (5) is connected with control circuit plate, and control circuit plate circuit ground with electrode detector be connected, it is ensured that the unification of earth point position.
Front end adopts flexible PCB as the electrode detector array of substrate, is connected with controlled path selector by shielded cable, and then is connected with single-chip computer control system.Signal controls end and includes: the input of signal front end photoelectric coupling amplification module, low-pass filtering module, single chip control module, output amplification module, external memory module, input keyboard, described single chip control module is connected with memory module by serial port, and described external memory module adopts E2ROM chip or FLASH flash chip.The state of channel to channel adapter is controlled by mcu programming, the electrode realizing electrod-array selects, and determine that mode of operation is input or output, if input pattern, then signal inputs single-chip microcomputer after photoelectric coupling, amplifying circuit, low-pass filter circuit, single-chip microcomputer input interface, and then it is stored in external memory module by Single Chip Microcomputer (SCM) system, it is achieved the collection of electrode signal；If output mode, the signal then produced according to Single Chip Microcomputer (SCM) program specifies, by being added to after amplification module, channel to channel adapter, the excitation realizing electrode signal on electrode, and especially, the signal exported in such a mode is 0, then electrode potential is 0, and duty is ground connection (shielding)；By single-chip microcomputer, the circulation of each passage of channel to channel adapter is selected, it is achieved the control of all electrode condition on electrod-array.Single Chip Microcomputer (SCM) system is used to set the duty of each electrode respectively by address wire, data wire, for the one in ground electrode (bucking electrode), detection electrode, exciting electrode.
Described photoelectric coupling amplification module adopts OPA series photoelectric coupling integration amplification chip, and described low-pass filtering module adopts the fertile husband's wave filter of second order Bart, and cut-off frequency is designed as 11kHz-15kHz, and described channel to channel adapter can adopt 1-3 sheet CD4067 chip.
The PCB design of this control system adopts the method for designing that many group screens cover, and its ground wire adopts the ultra-wide wiring of 2-3mm, and cabling is shaped as closed loop and surrounds form, so that the electrode within the scope of ground wire encirclement realizes higher isolation effect.
Single-chip Controlling flow process is as follows:
1, first the electrode points of four positions, corner of electrod-array and four electrode points of center are scanned in the unloaded state, it is judged that the error of its level, if more than 5%, are then calibrated by the temperature of change electrode unit.By the heating resistor output of Single-chip Controlling zones of different, until systematic error meets the requirements.
2, set one by one by the input to electrode points of user's keyboard and output state.
3, preset input signal is selected.Typical input signal may select: square wave, triangular wave, sine wave, high level, low level.Concurrently set the input peak-to-peak value (mV) of signal, the cycle (ms).
4, according to setting, electrode being driven, the data of scanning probe electrode points, store it in memory cell simultaneously.
The organism body surface electric signals detection electrode of the present invention, adopt the carrier that material flexible, insulation is arranged as electrod-array, electrode base presents hemispherical surface and contacts with body surface, all electrodes can need to realize programming according to bio signal detection, signal generator can be connected as exciting electrode, can also connect oscillograph or signal pickup assembly as detection electrode, can also ground connection as bucking electrode.If need detection constant level transmission characteristic in vivo, it is also possible to detection or exciting electrode are directly set as high/low level position, it may be achieved the high speed of organism surface signal, flexibility measurement.
The control end of this detection system includes following several parts composition: circuit substrate, singlechip chip and peripheral circuit, switch arrays and address wire thereof and data wire, signal acquisition circuit module, memory module, signal stimulating module, host computer communication module, input keyboard module and display module.
Switch arrays, with single-chip microcomputer for core, are controlled by this system, and on off state is conducting, then corresponding port is to be measured or excitation state, and it is ground state that on off state disconnects then corresponding port, presents low level.Switch arrays are by address wire and data wire and single chip communication, and accept Single-chip Controlling.
Signal acquisition circuit includes pre-amplifier, photoelectric coupling circuit, power isolation module and low pass filter.Described pre-amplifier selects three groups of common amplifier device composition differential amplifiers to suppress common-mode noise；Photoelectric coupling circuit selects the internal integral type instrumentation amplifier with Phototube Coupling, and power isolation module selects DC/DC isolating chip.Low pass filter adopts Butterworth second order filter, and cut-off frequency is 8kHz-15kHz.
Above-mentioned module adopts one point grounding mode ground connection, and controls Modular surface employing metallic shield to stop electromagnetic interference.
Compared with existing electro physiology Detection Techniques, the present invention has following technical effect that
1) can detect simultaneously or encourage by on-plane surface multiple spot, and realizing high speed, high-throughout test and storage.
2) when actual detection is applied, this detection electrode system only need to be fixed once, and follow-up each electrode condition can realize according to mcu programming, with the concordance of guarantee test condition to greatest extent.
3) electrod-array adopts flexible PCB as substrate, can fit according to organism surface shape, plates silver chloride as nonpolarizable electrode at electrode surface simultaneously, reduces the introducing of contact link noise to greatest extent.
4) by setting the ground connection of the electrode several, a row or multi-row on electrod-array, it is possible to effectively realize pumping signal, detectable signal in isolation electrically, to prevent the appearance of artefact.
5) have employed Intelligent Single-Chip Based control, multiple connected mode, Low Noise Design etc. for the detection system of this electrode array designs, it is achieved that for the efficient detection of body surface electricity physiological signal.
Accompanying drawing explanation
Fig. 1 is that organism surface ultra-weak electronic signal gathers and excitation Control system architecture block diagram.
Fig. 2 is the electrod-array schematic top plan view for the detection of the body surface meridians signal of telecommunication.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention being elaborated, as shown in Figure 1 and Figure 2, adopt the soft material of surface insulation as carrier, electrode unit is arranged on strip-like carrier according to the form of array, and its strip-like carrier adopts flexible PCB as substrate.Carrier is provided with the electrode arrangement point position of array-like, each some position arranges pad, and on circuit boards by the mode of printed wiring, each electrode points position pad being electrically connected to common interface end, common interface end can detection/excitation and level to sensing point electrode be controlled as required.On electrode points position, realized the electrical connection of scolding tin and pad by the mode of scolding tin filling pad.Scolding tin packed height should be uniformly controlled at 2mm, is shaped as hemispherical, plated surface silver chloride, avoids oxidized to adapt to the environment of repetitive measurement.
Adopt low frequency shielded cable, it is preferable that coaxial cable makes connecting line component, it is to avoid the interfering with each other and introduce noise of ultra-weak electronic signal.Its wiring includes the data connecting line of each electrode points, ground signalling transmission special circuit.Data connecting line and ground signal line are staggered the crosstalk reducing between holding wire to greatest extent.Output port is connected with control circuit plate, and control circuit plate circuit ground with electrode detector be connected, it is ensured that the unification of earthing potential.
Front end adopts flexible PCB as the electrode detector array of substrate, is connected with controlled path selector by shielded cable, and then is connected with single-chip computer control system.Signal controls end and includes: the input of signal front end photoelectric coupling amplification module, low-pass filtering module, single chip control module, output amplification module, external memory module, input keyboard, described single chip control module is connected with memory module by serial port, and described external memory module adopts E2ROM chip or FLASH flash chip.The state of channel to channel adapter is controlled by mcu programming, the electrode realizing electrod-array selects, and determine that mode of operation is input or output, if input pattern, then signal inputs single-chip microcomputer after photoelectric coupling, amplifying circuit, low-pass filter circuit, single-chip microcomputer input interface, and then it is stored in external memory module by Single Chip Microcomputer (SCM) system, it is achieved the collection of electrode signal；If output mode, the signal then produced according to Single Chip Microcomputer (SCM) program specifies, by being added to after amplification module, channel to channel adapter, the excitation realizing electrode signal on electrode, and especially, the signal exported in such a mode is 0, then electrode potential is 0, and duty is ground connection (shielding)；By single-chip microcomputer, the circulation of each passage of channel to channel adapter is selected, it is achieved the control of all electrode condition on electrod-array.Single Chip Microcomputer (SCM) system is used to set the duty of each electrode respectively by address wire, data wire, for the one in ground electrode (bucking electrode), detection electrode, exciting electrode.
Whole electrode base board is divided into two regions.According to experimental program, Single Chip Microcomputer (SCM) system is used to set the duty of each electrode respectively by address wire, data wire, for the one in ground electrode, detection electrode, exciting electrode.Realize excitation, detectable signal in isolation electrically, electrode is formed a signal transmission passage.
Preset input signal is selected.Typical input signal may select: square wave, triangular wave, sine wave, high level, low level.Concurrently set the peak-to-peak value (mV) of output drive signal, cycle (ms) and the collection period of detection electrode, it is preferred to 0.05ms.According to setting, electrode is driven, simultaneously by the data of concurrently or sequentially mode scanning probe electrode points, it is stored in a memory cell with the form of discrete data point.
Claims (6)
1. an organism surface ultra-weak electronic signal gathers and excitation control system, it is characterised in that: front end adopts flexible PCB as the electrode detector array of substrate, is connected with controlled path selector by shielded cable, and then is connected with single-chip computer control system.Signal controls end and includes: the input of signal front end photoelectric coupling amplification module, low-pass filtering module, single chip control module, output amplification module, external memory module, input keyboard, described single chip control module is connected with memory module by serial port.The state of channel to channel adapter is controlled by mcu programming, the electrode realizing electrod-array selects, and determine that mode of operation is input or output, if input pattern, then signal inputs single-chip microcomputer after photoelectric coupling, amplifying circuit, low-pass filter circuit, single-chip microcomputer input interface, and then it is stored in external memory module by Single Chip Microcomputer (SCM) system, it is achieved the collection of electrode signal；If output mode, the signal then produced according to Single Chip Microcomputer (SCM) program specifies, by being added to after amplification module, channel to channel adapter, the excitation realizing electrode signal on electrode, and especially, the signal exported in such a mode is 0, then electrode potential is 0, and duty is ground connection (shielding)；By single-chip microcomputer, the circulation of each passage of channel to channel adapter is selected, it is achieved the control of all electrode condition on electrod-array.
2. organism surface ultra-weak electronic signal according to claim 1 gathers and excitation control system, it is characterized in that: use Single Chip Microcomputer (SCM) system to set the duty of each electrode respectively by address wire, data wire, for the one in ground electrode (bucking electrode), detection electrode, exciting electrode.
3. organism surface ultra-weak electronic signal according to claim 1 gathers and excitation control system, it is characterized in that: described photoelectric coupling amplification module adopts OPA series photoelectric coupling integration amplification chip, described low-pass filtering module adopts the fertile husband's wave filter of second order Bart, and cut-off frequency is designed as 11kHz-15kHz.
4. organism surface ultra-weak electronic signal according to claim 1 gathers and excitation control system, it is characterised in that: described channel to channel adapter can adopt 1-3 sheet CD4067 chip.
5. organism surface ultra-weak electronic signal according to claim 1 gathers and excitation control system, it is characterised in that: described external memory module adopts E2ROM chip or FLASH flash chip.
6. organism surface ultra-weak electronic signal according to claim 1 and 2 gathers and excitation control system, it is characterised in that: described employing flexible PCB is as the electrode detector array of substrate, and printed circuit board ground width is 2-3mm.
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| CN201610153586.4A CN105769165B (en) | 2016-03-17 | 2016-03-17 | The acquisition of organism surface ultra-weak electronic signal and excitation control system |
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| CN201610153586.4A CN105769165B (en) | 2016-03-17 | 2016-03-17 | The acquisition of organism surface ultra-weak electronic signal and excitation control system |
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| CN105769165B CN105769165B (en) | 2019-05-21 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110226927A (en) * | 2018-03-05 | 2019-09-13 | 郑惇方 | Bio-energy signal acquisition and conversion equipment |
| CN113093061A (en) * | 2021-04-22 | 2021-07-09 | 北京机械设备研究所 | Flexible array electrode on-off detection method based on sweep frequency screening |
| CN113425314A (en) * | 2021-05-26 | 2021-09-24 | 上海理工大学 | Array type high-density surface myoelectricity acquisition device and myoelectricity acquisition method |
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| CN2157794Y (en) * | 1993-04-15 | 1994-03-02 | 李笑田 | Multi-channel dot matrix electrode probe |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110226927A (en) * | 2018-03-05 | 2019-09-13 | 郑惇方 | Bio-energy signal acquisition and conversion equipment |
| CN113093061A (en) * | 2021-04-22 | 2021-07-09 | 北京机械设备研究所 | Flexible array electrode on-off detection method based on sweep frequency screening |
| CN113425314A (en) * | 2021-05-26 | 2021-09-24 | 上海理工大学 | Array type high-density surface myoelectricity acquisition device and myoelectricity acquisition method |
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| CN105769165B (en) | 2019-05-21 |
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