CN105767551A - Piglet intestinal physiology regulating feed additive and use method thereof - Google Patents
Piglet intestinal physiology regulating feed additive and use method thereof Download PDFInfo
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Abstract
The present invention discloses a piglet intestinal physiology regulating feed additive added into piglet daily diet and a use method thereof. The feed additive includes the following main ingredients: 300-370 parts of calcium sulfate dihydrate, 20-40 parts of plant extracts, 10-20 parts of glutamic acid, 10-20 parts of aspartic acid, 20-30 parts of L-lysine and 40-100 parts of a carrier. The provided feed additive is mainly used in the weaned piglet daily diet at a ratio of 0.05-0.5 wt%. A feeding experiment proves that the additive can improve the granulation effect of a feed, and has very significant effects in regulating the intestinal pH value of the piglets, improving the absorption efficiencies of the piglets for calcium and other nutrients in daily diet, and promoting the growth of the piglets. The features of the invention are as follows: the feed additive can regulate intestinal acid-base balance, promote intestinal tract absorptions of the calcium and other nutrients, reduce diarrhea incidence, and promote animal growth, and is a safe, non-toxic, free of side effects, free of drug residues, and green feed additive.
Description
Technical field
The present invention relates to a kind of regulation physiological feed addictive of intestine of young pigs, belong to field of feed additive technology.
Background technology
Piglet health is the key of Swine Production, and intestinal health is core and the basis of fast-growth of Piglet Development.Especially
It is when weaned piglet, and piglet to face such as daily ration change, a large amount of physiological stresses such as female young separation, environmental change, causes son
Chitling road generation histology and physiological change, cause piglet indigestion and absorption function to decline, even immunity function fall
Low, thus suffer from diarrhoea, the situation such as growthing lag, reduce weaned piglets.Therefore, regulate intestine of young pigs acid-base balance,
Intestinal health is maintained to be to ensure that the key of piglet growth, particularly significant to whole industry meaning of raising pigs.Forefathers are used for protecting piglet to be good for
The means of health are nothing more than increasing feed nutrition concentration, or adding antibiosis in piglet diet usually reduces the generation of disease or diarrhoea.
But from the point of view of the actual conditions of piglet cultivation, these methods do not show particularly preferred effect, and Long-Time Service antibiotic
Easily have side effects.Therefore, increasing researcher starts to explore regulation intestine of young pigs physiology, maintains the side that piglet is healthy
Method.
Calcium is to maintain piglet healthy, ensures the very important mineral nutrient element of piglet growth.Calcium and protein specific bond
Form calbindin (CaBP), be the important component of Second messenger in cell system, in Ca signal system is conducted, play key
Effect, mainly show as physiological metabolism and gene expression, control the normal g and D of cell.CaBP contains in a large number
Lysine (Lys), when lysine deficiency, CaBP synthesizes decline, and calcium uptake reduces.In piglet diet, supplement Lys can promote
Enter the small intestine absorption to calcium, thus the formation of beneficially CaBP.The factor affecting calcium uptake is a lot, such as intake, the day of calcium
Grain calcium-phosphorus ratio, the dissociated state etc. of calcium all can affect the absorption of calcium.In calcium sulphate dihydrate, Ca content is 21.85%, relative stone flour
Biological value be 104%, the absorption efficiency in enteron aisle is higher.It addition, GI physiological status is also to affect calcium uptake
Key factor, Chinese herbal medicine extract can effectively regulating intestinal canal acid-base balance and physiological status, reduce calcium and other materials in enteric cavity
In conjunction with producing precipitation, maintain its ionization state, reach optimal absorption effect.
Summary of the invention
It is an object of the invention to provide a kind of regulation physiological feed addictive of intestine of young pigs and using method thereof, be by following skill
Art scheme realizes:
A kind of regulation physiological feed addictive of intestine of young pigs, by weight, by calcium sulphate dihydrate 300～370 parts, plant extracts
Preparation 20～40 parts, glutamic acid 10～20 parts, aspartic acid 10～20 parts, 1B 20～40 parts, carrier 40～100 parts of groups
Become.
Preferably scheme has, by weight by calcium sulphate dihydrate 300～350 parts, vegetable extract pre-parations 20～30 parts, paddy ammonia
Acid 10～15 parts, aspartic acid 10～12 parts, 1B 25～30 parts, carrier 40～60 parts of compositions；Or by two water sulphur
Acid calcium 350～370 parts, vegetable extract pre-parations 30～40 parts, glutamic acid 15～20 parts, aspartic acid 15～20 parts, L-rely ammonia
Acid 25～30 parts, carrier 60～100 parts of compositions；Or by calcium sulphate dihydrate 250～300 parts, vegetable extract pre-parations 25～35
Part, glutamic acid 15～20 parts, aspartic acid 10～15 parts, 1B 25～30 parts, carrier 40～80 parts of compositions；Or by
Calcium sulphate dihydrate 320～370 parts, vegetable extract pre-parations 20～35 parts, glutamic acid 10～215 parts, aspartic acid 15～20 parts,
1B 20～25 parts, carrier 80～100 parts of compositions.Described vegetable extract pre-parations is by folium isatidis water crude extract preparation or dent
Amaranth water crude extract preparation or the two mixing composition.Can also be directly raw material with folium isatidis and purslane, the most directly carry out
Adding, its addition can convert by the amount of extract.
In described vegetable extract pre-parations, folium isatidis water crude extract preparation and Portulaca water crude extract preparation, can be one of which,
Can also be the mixture of two kinds, when for the mixture of two kinds, its ratio can be any, it is also possible to is 1:1～3, plants for two kinds
Thing extract or vegetable extract pre-parations can be bought from market, or prepare in accordance with the following methods.
The preparation method of described plant extracts folium isatidis water CE preparation: extracting method is by known to a person skilled in the art
Method carry out, mainly folium isatidis is slightly pulverized, with the distilled water soak at room temperature 24 of 5 times of volumes～48 hours, coarse filtration was gone
Slag, soak is clarified, filter, after being concentrated by evaporation to 1/2, then by spray drying process, concentrate is dried to powder.Then
Folium isatidis water CE dry powder, dextrin, flour are mixed according to the ratio of 2:1:1, is prepared as graininess folium isatidis water crude extract
Preparation.Per kilogram folium isatidis can be made into water crude extract preparation 0.4kg.
The preparation method of described plant extracts Portulaca water crude extract preparation: its extracting method is by known to a person skilled in the art
Method carry out, mainly purslane is slightly pulverized, with the distilled water soak at room temperature 24 of 5 times of volumes～48 hours, coarse filtration was gone
Slag, soak is clarified, filter, after being concentrated by evaporation to 1/2, then by spray drying process, concentrate is dried to powder.Then
Portulaca water CE dry powder, dextrin, flour are mixed according to the ratio of 2:1:1, is prepared as graininess Portulaca water crude extract
Preparation, per kilogram purslane can be made into water crude extract preparation 0.4kg.
The preparation method of the physiological feed addictive of regulation intestine of young pigs of the present invention, sequentially includes the following steps:
By above-mentioned formula, weigh each component respectively, first calcium sulphate dihydrate and carrier are pulverized, cross 40 mesh sieves standby, by weight
Number weighs vegetable extract pre-parations, after mixing with the carrier of 0.5～1 times amount, adds glutamic acid, aspartic acid and L-and relies ammonia
Acid mixes, then mixes with calcium sulfate and residue carrier, finally obtains the regulation physiological feed addictive of intestine of young pigs.
The using method of the physiological feed addictive of regulation intestine of young pigs of the present invention:
The physiological feed addictive of intestine of young pigs will be regulated, add weanling pig full price to according to the ratio of 0.05%-0.5WT% and join
Close in daily ration, stir rear Direct-fed or make pellet and feed.
Advantages of the present invention:
The physiological feed addictive of regulation intestine of young pigs of the present invention is according to intestine of young pigs physilogical characteristics, and calbindin
(CaBP) is as the important component of Second messenger in cell system, regulation and control physiological metabolism and the mechanism of cell growth in vain, selects easily quilt
The calcium source calcium sulphate dihydrate absorbed and the raw material amino acid of composition CaBP, regulate intestine of young pigs acid-base balance in conjunction with plant extracts,
Thus improve piglet physiological status, promote that enteron aisle, to calcium and the absorption of other nutriments, reduces diarrhoea and occurs, promote growth.
Calcium feed addictive has the features such as wide material sources, safety non-toxic, without any side effects, drug residue free, and preparation method letter
Single easy, safe and reliable.The regulation physiological feed addictive of intestine of young pigs of the present invention is applicable to the piglet of various kind and uses.
Said preparation adds in piglet diet, can improve feed granulating effect, effectively regulation intestine of young pigs acid-base balance, improves feed and supports
Divide utilization rate, reduce diarrhea rate, promote piglet growth.
Detailed description of the invention:
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment, the present invention is made into one
Step describes in detail.But example is not as a limitation of the invention.
Embodiment 1
A kind of regulation physiological feed addictive of intestine of young pigs, main component calcium sulphate dihydrate 350 parts, vegetable extract pre-parations 40
Part, 10 parts of glutamic acid, aspartic acid 20 parts, 1B 30 parts, 50 parts of carrier.Select 72 body conditions good, body weight
21 close age in days DLY piglets, are divided into 2 process, each process 6 repetition, each repetition 6.Control group fed
Basal diet, test group daily ration adds the additive for feed for piglets of 0.1% present invention in basal diet.Feeding and management and immunity journey
Sequence is carried out according to routine, and experimental period is 14d.Result of the test is as follows:
Table 1 piglet growth performance and diarrhea rate result
| Test group | Control group | |
| Just starting weight (kg) | 8.78±0.19a | 8.76±0.13a |
| End weight (kg) | 10.75±1.52a | 10.08±0.86b |
| Average daily gain (kg/d) | 0.37±0.04a | 0.21±0.07b |
| Average feed intake (kg/d) | 0.32±0.02a | 0.25±0.10b |
| Feed-weight ratio | 1.90±0.90a | 2.20±0.52b |
| Diarrhea rate (%) | 10.59±0.87a | 13.02±1.56b |
Note: without letter or data shoulder mark same letter, colleague represents that difference is not notable (P > 0.05), different lowercase alphabet differentials are different aobvious
Writing (P < 0.05), different capitalizations represent that difference is extremely notable (P < 0.01).
As seen from the results in Table 1, test group is different not notable (P > 0.05) with the initial method of double differences of control group piglet, test group end weight peace
All daily gains are all remarkably higher than control group (P < 0.05).The feed intake of test group is higher than control group, and difference also reaches the level of signifiance
(P<0.05).The feed-weight ratio of test group is only 1.90, substantially less than the 2.20 of control group, and significant difference (P < 0.05).Examination
Testing group diarrhea rate relatively control group and reduce 2.43%, difference is also notable (P < 0.05).
Embodiment 2
A kind of regulation physiological feed addictive of intestine of young pigs, after 40 parts of vegetable extract pre-parations and 40 parts of carrier mixing, with
20 parts of glutamic acid, 20 parts of aspartic acids and 40 parts of 1Bs stir, then with 300 parts of calcium sulphate dihydrates and 40 parts of loads
Body is prepared from after being sufficiently mixed uniformly." Du × long × big " three way cross piglet 72 of wean about 28 ages in days is chosen in test,
The principle similar by body weight, sex, hereditary basis is randomly divided into 4 process, each process 3 hurdle, each process 6 (3
Male 3 is female).In 4 basal diets processed, the intestine of young pigs of interpolation 0%, 0.05%, 0.10%, 0.20% is physiological respectively
Feed addictive.Test pig uses high bed to raise, free choice feeding and drinking-water, and immunity and disinfectant program are carried out by pig farm routine, examination
Test phase 28d.Result of the test is as follows:
The impact on Growth Performance of Weaning Piglets of the table 2 intestine of young pigs physiological regulation agent
| Project | 0% | 0.05% | 0.10% | 0.20% |
| Just starting weight kg | 7.64±0.03 | 7.64±0.04 | 7.66±0.03 | 7.65±0.05 |
| End weight kg | 14.22±0.88b | 15.92±0.58ab | 15.02±1.73ab | 16.78±1.66a |
| ADG g/d | 244.42±33.46b | 297.98±28.36ab | 263.22±47.58ab | 326.09±42.66a |
| ADFI g/d | 493.73±56.83b | 560.73±78.95ab | 520.67±35.46ab | 595.24±78.40a |
| F/G | 2.02±0.20 | 1.88±0.27 | 1.97±0.58 | 1.83±0.26 |
| Diarrhea rate % | 22.37±6.78A | 13.12±6.59AB | 12.49±3.94AB | 4.86±5.33B |
Note: without letter or data shoulder mark same letter, colleague represents that difference is not notable (P > 0.05), different lowercase alphabet differentials are different aobvious
Writing (P < 0.05), different capitalizations represent that difference is extremely notable (P < 0.01).
During off-test, by the result of table 2 it can be seen that the end weight of 0.20% group of piglet, average daily ingestion amount and average daily gain
The highest, respectively 16.78kg, 595.24g/d and 326.09g/d, not notable (P > 0.05) with 0.05% group and 0.10% group of difference,
It is significantly higher than control group (0%) (P < 0.05)；Feed-weight ratio is also minimum with 0.20% group, and only 1.83, do not show with other three groups of differences
Write (P > 0.05)；Diarrhea rate 0.20% group is minimum, and only 4.86%, pole is substantially less than 22.37% (P < 0.05) of control group,
Not notable (P > 0.05) with other two groups of differences.
The constituent of the present invention is calcium sulfate, vegetable extract pre-parations, glutamic acid, aspartic acid, 1B and carrier,
Without any side effects, and environment is not had any pollution.Therefore, this achievement such as obtains popularization and application on a large scale, supports China
The sustainable health development growing industry is significant.This achievement economic benefit and social benefit are notable.
Embodiment 3 weighs the weanling pig full price ration formulation of constant weight, then according to weight ratio weighs regulation intestine of young pigs life
The feed addictive of reason, its ratio is added in weanling pig full price ration formulation according to the ratio of 0.05%WT%, is sufficiently stirred for
Direct-fed or make pellet and feed after uniformly.
Embodiment 4 weighs the weanling pig full price ration formulation of constant weight, then according to weight ratio weighs regulation intestine of young pigs life
The feed addictive of reason, its ratio is added in weanling pig full price ration formulation according to the ratio of 0.5%WT%, is sufficiently stirred for
Direct-fed or make pellet and feed after uniformly.
Embodiment 5 weighs the weanling pig full price ration formulation of constant weight, then according to weight ratio weighs regulation intestine of young pigs life
The feed addictive of reason, its ratio is added in weanling pig full price ration formulation according to the ratio of 0.25%WT%, is sufficiently stirred for
Direct-fed or make pellet and feed after uniformly.
Claims (5)
1. the regulation physiological feed addictive of intestine of young pigs, it is characterised in that: by weight, calcium sulphate dihydrate 300～370
Part, vegetable extract pre-parations 20～40 parts, glutamic acid 10～20 parts, aspartic acid 10～20 parts, 1B 20～30 parts,
Carrier 40～100 parts of compositions, described vegetable extract pre-parations is folium isatidis water crude extract preparation and the one of Portulaca water crude extract preparation
Plant or two kinds.
A kind of regulation physiological feed addictive of intestine of young pigs the most according to claim 1, it is characterised in that: described plant
Extract formulation is folium isatidis water crude extract preparation when mixing with Portulaca water crude extract preparation, and its ratio is 1:1～3.
3. the compound method regulating the physiological feed addictive of intestine of young pigs, it is characterised in that: in terms of parts by weight, by power
Profit requires to fill a prescription described in 1, weighs each component respectively, after the carrier of vegetable extract pre-parations and 0.5～1 times amount is mixed,
Add glutamic acid, aspartic acid and 1B to mix, then mix with calcium sulphate dihydrate and residue carrier, finally
To the regulation physiological feed addictive of intestine of young pigs.
4. the using method regulating the physiological feed addictive of intestine of young pigs, it is characterised in that: by the ratio of 0.05%-0.5WT%
Example is added in weanling pig full price ration formulation, stirs rear Direct-fed or makes pellet and feed.
5. the regulation physiological feed addictive of intestine of young pigs as claimed in claim 1 a kind of regulation intestine of young pigs is physiological should
With.
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Cited By (2)
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| CN111700169A (en) * | 2020-05-28 | 2020-09-25 | 中国科学院亚热带农业生态研究所 | Feed additive for improving immunity of growing pigs and application thereof |
| CN111700173A (en) * | 2020-05-28 | 2020-09-25 | 湖南师范大学 | Feed additive for improving growth performance of 22-55kg live pigs and application thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111700169A (en) * | 2020-05-28 | 2020-09-25 | 中国科学院亚热带农业生态研究所 | Feed additive for improving immunity of growing pigs and application thereof |
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Application publication date: 20160720 |