CN105755065A - 赖氨酸的发酵及其中所用的设备和部件 - Google Patents
赖氨酸的发酵及其中所用的设备和部件 Download PDFInfo
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- CN105755065A CN105755065A CN201410777788.7A CN201410777788A CN105755065A CN 105755065 A CN105755065 A CN 105755065A CN 201410777788 A CN201410777788 A CN 201410777788A CN 105755065 A CN105755065 A CN 105755065A
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- 238000000034 method Methods 0.000 title claims abstract description 25
- 239000004472 Lysine Substances 0.000 title abstract description 13
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title description 9
- 102000000818 NADP Transhydrogenases Human genes 0.000 claims abstract description 38
- 108010001609 NADP Transhydrogenases Proteins 0.000 claims abstract description 38
- 241000894006 Bacteria Species 0.000 claims abstract description 22
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- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 22
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 22
- 239000001963 growth medium Substances 0.000 claims description 21
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 20
- 239000004744 fabric Substances 0.000 claims description 20
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- 239000008103 glucose Substances 0.000 claims description 13
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 11
- 229960002685 biotin Drugs 0.000 claims description 11
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- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 claims description 10
- 229910000359 iron(II) sulfate Inorganic materials 0.000 claims description 10
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 10
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 claims description 10
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- 235000013379 molasses Nutrition 0.000 claims description 10
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- 238000012366 Fed-batch cultivation Methods 0.000 claims description 7
- 239000002054 inoculum Substances 0.000 claims description 6
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 6
- 238000009923 sugaring Methods 0.000 claims description 6
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- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 2
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- 235000001727 glucose Nutrition 0.000 description 14
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- 229940023064 escherichia coli Drugs 0.000 description 5
- 150000002304 glucoses Chemical class 0.000 description 5
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- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
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- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
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CN201410777788.7A CN105755065B (zh) | 2014-12-17 | 2014-12-17 | 赖氨酸的发酵及其中所用的设备和部件 |
CN201811225779.1A CN109370882B (zh) | 2014-12-17 | 2014-12-17 | 赖氨酸的发酵中所用的设备和部件 |
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CN201410777788.7A CN105755065B (zh) | 2014-12-17 | 2014-12-17 | 赖氨酸的发酵及其中所用的设备和部件 |
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CN201811225779.1A Division CN109370882B (zh) | 2014-12-17 | 2014-12-17 | 赖氨酸的发酵中所用的设备和部件 |
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CN105755065A true CN105755065A (zh) | 2016-07-13 |
CN105755065B CN105755065B (zh) | 2019-01-08 |
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CN201410777788.7A Active CN105755065B (zh) | 2014-12-17 | 2014-12-17 | 赖氨酸的发酵及其中所用的设备和部件 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110042043A (zh) * | 2019-04-24 | 2019-07-23 | 王珍 | 一种微生物发酵用分压式发酵设备 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102191289A (zh) * | 2011-03-18 | 2011-09-21 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的发酵制备 |
CN102234666A (zh) * | 2011-06-08 | 2011-11-09 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的流加发酵制备 |
CN102318739A (zh) * | 2011-06-08 | 2012-01-18 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的三级发酵及其包被制品 |
Family Cites Families (5)
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GB357783A (en) * | 1929-09-28 | 1931-10-01 | Meissner Fa Josef | A process for the continuous production of pentaerythrite |
CN100513549C (zh) * | 2006-02-23 | 2009-07-15 | 文红涛 | 液态菌蕈生产方法及其液态菌蕈发酵设备 |
CN201704332U (zh) * | 2010-06-10 | 2011-01-12 | 贵州大学 | 小户型连续式太阳能生物质能发酵装置 |
CN102234667B (zh) * | 2011-06-08 | 2012-08-15 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的三级发酵制备 |
CN203955232U (zh) * | 2014-06-04 | 2014-11-26 | 江苏洁净环境科技有限公司 | 餐饮垃圾处理用热水解装置 |
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2014
- 2014-12-17 CN CN201811225779.1A patent/CN109370882B/zh active Active
- 2014-12-17 CN CN201410777788.7A patent/CN105755065B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102191289A (zh) * | 2011-03-18 | 2011-09-21 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的发酵制备 |
CN102234666A (zh) * | 2011-06-08 | 2011-11-09 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的流加发酵制备 |
CN102318739A (zh) * | 2011-06-08 | 2012-01-18 | 宁夏伊品生物科技股份有限公司 | 赖氨酸的三级发酵及其包被制品 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110042043A (zh) * | 2019-04-24 | 2019-07-23 | 王珍 | 一种微生物发酵用分压式发酵设备 |
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Publication number | Publication date |
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CN109370882A (zh) | 2019-02-22 |
CN105755065B (zh) | 2019-01-08 |
CN109370882B (zh) | 2021-08-20 |
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Denomination of invention: Lysine fermentation method, and device and part used in method Effective date of registration: 20200120 Granted publication date: 20190108 Pledgee: Yongning County Branch of China Agricultural Development Bank Pledgor: INNER MONGOLIA EPPEN BIOTECH Co.,Ltd. Registration number: Y2020640000002 |
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Denomination of invention: Fermentation of lysine and the equipment and parts used in it Effective date of registration: 20210127 Granted publication date: 20190108 Pledgee: Yongning County Branch of China Agricultural Development Bank Pledgor: INNER MONGOLIA EPPEN BIOTECH Co.,Ltd. Registration number: Y2021640000001 |
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Denomination of invention: Lysine fermentation and equipment and components used therein Effective date of registration: 20220323 Granted publication date: 20190108 Pledgee: Yongning County Branch of China Agricultural Development Bank Pledgor: INNER MONGOLIA EPPEN BIOTECH Co.,Ltd. Registration number: Y2022640000002 |
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Date of cancellation: 20230315 Granted publication date: 20190108 Pledgee: Yongning County Branch of China Agricultural Development Bank Pledgor: NINGXIA EPPEN BIOTECH Co.,Ltd.|INNER MONGOLIA EPPEN BIOTECH Co.,Ltd.|Heilongjiang Yipin Biotechnology Co.,Ltd. Registration number: Y2022640000002 |
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Denomination of invention: The fermentation of lysine and the equipment and components used in it Granted publication date: 20190108 Pledgee: Yongning County Branch of China Agricultural Development Bank Pledgor: NINGXIA EPPEN BIOTECH Co.,Ltd.|INNER MONGOLIA EPPEN BIOTECH Co.,Ltd.|Heilongjiang Yipin Biotechnology Co.,Ltd. Registration number: Y2024640000005 |
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